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Search results 201 to 252 out of 252 for Rad52

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Type Details Score
Allele
Rdm1<Gt(OST394717)Lex> | MGI:4304667
 
Name: RAD52 motif 1; gene trap OST394717, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Rdm1<Gt(OST410968)Lex> | MGI:4308538
 
Name: RAD52 motif 1; gene trap OST410968, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Rad52<Gt(OST424194)Lex> | MGI:4312480
 
Name: RAD52 homolog, DNA repair protein; gene trap OST424194, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Rad52<em1Cya> | MGI:7795731
Name: RAD52 homolog, DNA repair protein; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Rad52<em2Cya> | MGI:7795732
Name: RAD52 homolog, DNA repair protein; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
11914131 | -
 
First Author: Iyer LM
Year: 2002
Journal: BMC Genomics
Title: Classification and evolutionary history of the single-strand annealing proteins, RecT, Redbeta, ERF and RAD52.
Volume: 3
Pages: 8
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Publication
18085829 | -
First Author: Alvaro D
Year: 2007
Journal: PLoS Genet
Title: Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination.
Volume: 3
Issue: 12
Pages: e228
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Allele
Rad52<Gt(P022B06)Wrst> | MGI:3866160
 
Name: RAD52 homolog, DNA repair protein; gene trap P022B06, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Rad52<Gt(D161G03)Wrst> | MGI:3892557
 
Name: RAD52 homolog, DNA repair protein; gene trap D161G03, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Rdm1<Gt(IST10672D9)Tigm> | MGI:5143349
 
Name: RAD52 motif 1; gene trap IST10672D9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Rdm1<Gt(IST10921E1)Tigm> | MGI:5146434
 
Name: RAD52 motif 1; gene trap IST10921E1, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Rdm1<Gt(IST13210F8)Tigm> | MGI:5156280
 
Name: RAD52 motif 1; gene trap IST13210F8, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Rdm1<Gt(IST13339G2)Tigm> | MGI:5160168
 
Name: RAD52 motif 1; gene trap IST13339G2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Rad52<Gt(IST13955D4)Tigm> | MGI:5197385
 
Name: RAD52 homolog, DNA repair protein; gene trap IST13955D4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Rdm1<Gt(IST14351B11)Tigm> | MGI:5228549
 
Name: RAD52 motif 1; gene trap IST14351B11, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Rad52<em1Gpt> | MGI:7305137
Name: RAD52 homolog, DNA repair protein; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Rad52<em82Gpt> | MGI:7305138
Name: RAD52 homolog, DNA repair protein; endonuclease-mediated mutation 82, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7835416 | C57BL/6JCya-Rad52<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7838375 | C57BL/6JCya-Rad52<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Rad52/Rad52
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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GO Term
GO:0070312 | RAD52-ERCC4-ERCC1 complex
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Protein Domain
IPR016810 | Rad59
Type: Family
Description: Rad59 is a paralogue of Rad52 and is involved in double-strand breaks (DSBs) DNA repair during vegetative growth via recombination and single-strand annealing []. It is required for loading of Rad52 to DSBs [].
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Genotype
Genotype
Symbol: Atm/Atm Rad52/Rad52
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
Zygosity: cx
Has Mutant Allele: true
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Protein Domain
IPR037489 | RAD52-like
Type: Family
Description: Homologues of the DNA-repair protein RAD52 are present in all plants. There are two identified RAD52 genes in Arabidopsis thaliana (RAD52-1 and RAD52-2), which encode four open reading frames (ORFs) through differential splicing, each of which specifically localized to the nucleus, mitochondria, or chloroplast, which suggests a role in maintaining nuclear and organellar genomes. The diverse plant RAD52 proteins affect DNA repair and fertility [].
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Genotype
Genotype
Symbol: Rad52/Rad52 Rad54l/Rad54l
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Protein Domain
IPR042525 | Rad52_Rad59_Rad22_sf
Type: Homologous_superfamily
Description: The DNA single-strand annealing proteins (SSAPs), such as RecT, Red-beta, ERF and Rad52, function in RecA-dependent and RecA-independent DNA recombination pathways. This superfamily includes proteins related to Rad52. These proteins contain two helix-hairpin-helix motifs [].Rad52 was identified in Saccharomyces cerevisiae (Baker's yeast) as a component of the homologous recombination repair pathway and to play an important role in both meiotic and mitotic recombination. The human protein is highly homologous in both structure and function. Inthe presence of absence of DNA, Rad52 forms ring-shaped oligomers which bind both single and double stranded DNA, stimulating annealing of complimentary DNA strands and promoting ligation of both cohesive and blunt-end fragments. Rad52 may act as a recombination mediator, optimising catalysis of strand exchange by the Rad51 protein.A C-terminal self-association domain has been identified that mediates formation of higher order oligomers of Rad52 rings. Formation of these oligomers may be important for interaction with more than one DNA molecule [].
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Protein Domain
IPR034200 | RDM1_RRM
Type: Domain
Description: This entry represents the RNA recognition motif (RRM) of RDM1, also termed RAD52 homologue B, a novel factor involved in the cellular response to the anti-cancer drug cisplatin in vertebrates []. RDM1 contains a small RD motif that is shared with the recombination and repair protein RAD52, and an RNA recognition motif (RRM). The RD motif is responsible for the acidic pH-dependent DNA-binding properties of RDM1. It interacts with ss- and dsDNA, and may act as a DNA-damage recognition factor by recognizing the distortions of the double helix caused by cisplatin-DNA adducts in vitro. In addition, due to the presence of RRM, RDM1 can bind to RNA as well as DNA [].
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Publication
1302006 | J:1014
First Author: Chartier FL
Year: 1992
Journal: Nat Genet
Title: Construction of a mouse yeast artificial chromosome library in a recombination-deficient strain of yeast.
Volume: 1
Issue: 2
Pages: 132-6
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Publication
9108475 | J:39642
First Author: Essers J
Year: 1997
Journal: Cell
Title: Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination.
Volume: 89
Issue: 2
Pages: 195-204
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Publication
34798058 | J:325961
First Author: Zada D
Year: 2021
Journal: Mol Cell
Title: Parp1 promotes sleep, which enhances DNA repair in neurons.
Volume: 81
Issue: 24
Pages: 4979-4993.e7
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Publication
8406471 | J:13245
First Author: Hamvas RM
Year: 1993
Journal: Genomics
Title: YAC clone contigs surrounding the Zfx and Pola loci on the mouse X chromosome.
Volume: 17
Issue: 1
Pages: 52-8
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Publication
8812453 | J:46976
First Author: Shen Z
Year: 1996
Journal: Genomics
Title: UBL1, a human ubiquitin-like protein associating with human RAD51/RAD52 proteins.
Volume: 36
Issue: 2
Pages: 271-9
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Publication
8341671 | J:13206
First Author: Morita T
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: A mouse homolog of the Escherichia coli recA and Saccharomyces cerevisiae RAD51 genes.
Volume: 90
Issue: 14
Pages: 6577-80
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Publication
8805304 | J:34999
First Author: Kanaar R
Year: 1996
Journal: Curr Biol
Title: Human and mouse homologs of the Saccharomyces cerevisiae RAD54 DNA repair gene: evidence for functional conservation.
Volume: 6
Issue: 7
Pages: 828-38
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Publication
10209103 | J:146730
First Author: Tan TL
Year: 1999
Journal: Curr Biol
Title: Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation.
Volume: 9
Issue: 6
Pages: 325-8
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Publication
12727892 | J:83373
First Author: Savouret C
Year: 2003
Journal: EMBO J
Title: CTG repeat instability and size variation timing in DNA repair-deficient mice.
Volume: 22
Issue: 9
Pages: 2264-73
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Publication
30811824 | J:292589
First Author: Kwon MS
Year: 2019
Journal: FEBS J
Title: Brca2 abrogation engages with the alternative lengthening of telomeres via break-induced replication.
Volume: 286
Issue: 10
Pages: 1841-1858
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Publication
38030626 | J:343250
First Author: Ronson GE
Year: 2023
Journal: Nat Commun
Title: Mechanisms of synthetic lethality between BRCA1/2 and 53BP1 deficiencies and DNA polymerase theta targeting.
Volume: 14
Issue: 1
Pages: 7834
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Publication
18584027 | J:161655
First Author: Bennardo N
Year: 2008
Journal: PLoS Genet
Title: Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair.
Volume: 4
Issue: 6
Pages: e1000110
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Publication
24569637 | J:237465
First Author: Cheverud JM
Year: 2014
Journal: Heredity (Edinb)
Title: Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line.
Volume: 112
Issue: 5
Pages: 508-18
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Publication
15485900 | J:94149
First Author: Stark JM
Year: 2004
Journal: Mol Cell Biol
Title: Genetic steps of mammalian homologous repair with distinct mutagenic consequences.
Volume: 24
Issue: 21
Pages: 9305-16
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Publication
27480124 | J:237787
First Author: Liu X
Year: 2016
Journal: BMC Immunol
Title: Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Volume: 17
Issue: 1
Pages: 25
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Publication
16033648 | J:103446
 
First Author: McKee AE
Year: 2005
Journal: BMC Dev Biol
Title: A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
Volume: 5
Pages: 14
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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