| Type |
Details |
Score |
| Publication |
| First Author: |
Krispel CM |
| Year: |
2003 |
| Journal: |
J Neurosci |
| Title: |
Prolonged photoresponses and defective adaptation in rods of Gbeta5-/- mice. |
| Volume: |
23 |
| Issue: |
18 |
| Pages: |
6965-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xie K |
| Year: |
2012 |
| Journal: |
Psychopharmacology (Berl) |
| Title: |
Gβ5-RGS complexes are gatekeepers of hyperactivity involved in control of multiple neurotransmitter systems. |
| Volume: |
219 |
| Issue: |
3 |
| Pages: |
823-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nini L |
| Year: |
2012 |
| Journal: |
Endocrine |
| Title: |
Expression of the Gβ5/R7-RGS protein complex in pituitary and pancreatic islet cells. |
| Volume: |
42 |
| Issue: |
1 |
| Pages: |
214-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Q |
| Year: |
2017 |
| Journal: |
FASEB J |
| Title: |
Regulator of G-protein signaling Gβ5-R7 is a crucial activator of muscarinic M3 receptor-stimulated insulin secretion. |
| Volume: |
31 |
| Issue: |
11 |
| Pages: |
4734-4744 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Q |
| Year: |
2011 |
| Journal: |
FASEB J |
| Title: |
Targeted deletion of one or two copies of the G protein β subunit Gβ5 gene has distinct effects on body weight and behavior in mice. |
| Volume: |
25 |
| Issue: |
11 |
| Pages: |
3949-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang JH |
| Year: |
2011 |
| Journal: |
J Neurochem |
| Title: |
Knockout of G protein β5 impairs brain development and causes multiple neurologic abnormalities in mice. |
| Volume: |
119 |
| Issue: |
3 |
| Pages: |
544-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Q |
| Year: |
2020 |
| Journal: |
J Biol Chem |
| Title: |
The regulatory G protein signaling complex, Gβ5-R7, promotes glucose- and extracellular signal-stimulated insulin secretion. |
| Volume: |
295 |
| Issue: |
21 |
| Pages: |
7213-7223 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
De Nittis P |
| Year: |
2021 |
| Journal: |
J Med Genet |
| Title: |
Inhibition of G-protein signalling in cardiac dysfunction of intellectual developmental disorder with cardiac arrhythmia (IDDCA) syndrome. |
| Volume: |
58 |
| Issue: |
12 |
| Pages: |
815-831 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gnb5/Gnb5 |
| Background: |
either: (involves: 129S/SvEv * 129S1/Sv) or (involves: 129S/SvEv * 129S1/Sv * C57BL/6) |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gnb5/Gnb5 |
| Background: |
involves: 129S1/Sv |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gnb5/Gnb5 |
| Background: |
involves: 129S1/Sv * C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Umino Y |
| Year: |
2012 |
| Journal: |
J Neurosci |
| Title: |
The relationship between slow photoresponse recovery rate and temporal resolution of vision. |
| Volume: |
32 |
| Issue: |
41 |
| Pages: |
14364-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xie K |
| Year: |
2010 |
| Journal: |
Nat Neurosci |
| Title: |
Gbeta5 recruits R7 RGS proteins to GIRK channels to regulate the timing of neuronal inhibitory signaling. |
| Volume: |
13 |
| Issue: |
6 |
| Pages: |
661-3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhou H |
| Year: |
2012 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
GIRK channel modulation by assembly with allosterically regulated RGS proteins. |
| Volume: |
109 |
| Issue: |
49 |
| Pages: |
19977-82 |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE53411 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Martemyanov KA |
| Year: |
2005 |
| Journal: |
J Biol Chem |
| Title: |
R7BP, a novel neuronal protein interacting with RGS proteins of the R7 family. |
| Volume: |
280 |
| Issue: |
7 |
| Pages: |
5133-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stanwood GD |
| Year: |
2006 |
| Journal: |
Eur J Neurosci |
| Title: |
Genetic or pharmacological inactivation of the dopamine D1 receptor differentially alters the expression of regulator of G-protein signalling (Rgs) transcripts. |
| Volume: |
24 |
| Issue: |
3 |
| Pages: |
806-18 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ziccardi L |
| Year: |
2012 |
| Journal: |
J Neurosci |
| Title: |
Loss of retinoschisin (RS1) cell surface protein in maturing mouse rod photoreceptors elevates the luminance threshold for light-driven translocation of transducin but not arrestin. |
| Volume: |
32 |
| Issue: |
38 |
| Pages: |
13010-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sundermeier TR |
| Year: |
2014 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
R9AP overexpression alters phototransduction kinetics in iCre75 mice. |
| Volume: |
55 |
| Issue: |
3 |
| Pages: |
1339-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Song JH |
| Year: |
2007 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. |
| Volume: |
35 |
| Issue: |
2 |
| Pages: |
311-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rao A |
| Year: |
2007 |
| Journal: |
J Neurosci |
| Title: |
Gbeta5 is required for normal light responses and morphology of retinal ON-bipolar cells. |
| Volume: |
27 |
| Issue: |
51 |
| Pages: |
14199-204 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Posokhova E |
| Year: |
2010 |
| Journal: |
Circ Res |
| Title: |
RGS6/Gβ5 complex accelerates IKACh gating kinetics in atrial myocytes and modulates parasympathetic regulation of heart rate. |
| Volume: |
107 |
| Issue: |
11 |
| Pages: |
1350-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ostrovskaya OI |
| Year: |
2018 |
| Journal: |
J Neurosci |
| Title: |
Inhibitory Signaling to Ion Channels in Hippocampal Neurons Is Differentially Regulated by Alternative Macromolecular Complexes of RGS7. |
| Volume: |
38 |
| Issue: |
46 |
| Pages: |
10002-10015 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cao Y |
| Year: |
2008 |
| Journal: |
J Neurosci |
| Title: |
Targeting of RGS7/Gbeta5 to the dendritic tips of ON-bipolar cells is independent of its association with membrane anchor R7BP. |
| Volume: |
28 |
| Issue: |
41 |
| Pages: |
10443-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang J |
| Year: |
2024 |
| Journal: |
Am J Hum Genet |
| Title: |
The association of GNB5 with Alzheimer disease revealed by genomic analysis restricted to variants impacting gene function. |
| Volume: |
111 |
| Issue: |
3 |
| Pages: |
473-486 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
232
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
206
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
368
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sheng Y |
| Year: |
2021 |
| Journal: |
Sci Rep |
| Title: |
Molecular determinants of response kinetics of mouse M1 intrinsically-photosensitive retinal ganglion cells. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
23424 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
443
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
469
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
470
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
477
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
464
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
466
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
484
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Leo D |
| Year: |
2013 |
| Journal: |
Cell Tissue Res |
| Title: |
Transgenic mouse models for ADHD. |
| Volume: |
354 |
| Issue: |
1 |
| Pages: |
259-71 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
472
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
465
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
435
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
453
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
437
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
495
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
502
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
505
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
456
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
490
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gerhard DS |
| Year: |
2004 |
| Journal: |
Genome Res |
| Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
| Volume: |
14 |
| Issue: |
10B |
| Pages: |
2121-7 |
|
•
•
•
•
•
|