| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2089
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
91
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Trivedi D |
| Year: |
2012 |
| Journal: |
J Neurosci |
| Title: |
Live-cell imaging evidence for the ciliary transport of rod photoreceptor opsin by heterotrimeric kinesin-2. |
| Volume: |
32 |
| Issue: |
31 |
| Pages: |
10587-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Samaranayake S |
| Year: |
2018 |
| Journal: |
Front Mol Neurosci |
| Title: |
Enhanced Mutant Compensates for Defects in Rhodopsin Phosphorylation in the Presence of Endogenous Arrestin-1. |
| Volume: |
11 |
|
| Pages: |
203 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Loscher CJ |
| Year: |
2008 |
| Journal: |
Exp Eye Res |
| Title: |
A common microRNA signature in mouse models of retinal degeneration. |
| Volume: |
87 |
| Issue: |
6 |
| Pages: |
529-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Calabro KR |
| Year: |
2019 |
| Journal: |
Front Neurosci |
| Title: |
A Novel Mouse Model of MYO7A USH1B Reveals Auditory and Visual System Haploinsufficiencies. |
| Volume: |
13 |
|
| Pages: |
1255 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
737
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sakami S |
| Year: |
2011 |
| Journal: |
J Biol Chem |
| Title: |
Probing mechanisms of photoreceptor degeneration in a new mouse model of the common form of autosomal dominant retinitis pigmentosa due to P23H opsin mutations. |
| Volume: |
286 |
| Issue: |
12 |
| Pages: |
10551-67 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Azevedo AW |
| Year: |
2015 |
| Journal: |
Elife |
| Title: |
C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor. |
| Volume: |
4 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Comitato A |
| Year: |
2016 |
| Journal: |
Hum Mol Genet |
| Title: |
Dominant and recessive mutations in rhodopsin activate different cell death pathways. |
| Volume: |
25 |
| Issue: |
13 |
| Pages: |
2801-2812 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
O'Reilly M |
| Year: |
2007 |
| Journal: |
Am J Hum Genet |
| Title: |
RNA interference-mediated suppression and replacement of human rhodopsin in vivo. |
| Volume: |
81 |
| Issue: |
1 |
| Pages: |
127-35 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GarcÃa-Caballero C |
| Year: |
2018 |
| Journal: |
Mol Vis |
| Title: |
Photoreceptor preservation induced by intravitreal controlled delivery of GDNF and GDNF/melatonin in rhodopsin knockout mice. |
| Volume: |
24 |
|
| Pages: |
733-745 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gunes K |
| Year: |
2024 |
| Journal: |
Front Cell Dev Biol |
| Title: |
Preservation of vision by transpalpebral electrical stimulation in mice with inherited retinal degeneration. |
| Volume: |
12 |
|
| Pages: |
1412909 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Giannelli SG |
| Year: |
2018 |
| Journal: |
Hum Mol Genet |
| Title: |
Cas9/sgRNA selective targeting of the P23H Rhodopsin mutant allele for treating retinitis pigmentosa by intravitreal AAV9.PHP.B-based delivery. |
| Volume: |
27 |
| Issue: |
5 |
| Pages: |
761-779 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ortega JT |
| Year: |
2022 |
| Journal: |
J Neurosci Res |
| Title: |
Flavonoids improve the stability and function of P23H rhodopsin slowing down the progression of retinitis pigmentosa in mice. |
| Volume: |
100 |
| Issue: |
4 |
| Pages: |
1063-1083 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mitra RN |
| Year: |
2018 |
| Journal: |
Biomaterials |
| Title: |
Genomic form of rhodopsin DNA nanoparticles rescued autosomal dominant Retinitis pigmentosa in the P23H knock-in mouse model. |
| Volume: |
157 |
|
| Pages: |
26-39 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mao H |
| Year: |
2011 |
| Journal: |
Hum Gene Ther |
| Title: |
AAV delivery of wild-type rhodopsin preserves retinal function in a mouse model of autosomal dominant retinitis pigmentosa. |
| Volume: |
22 |
| Issue: |
5 |
| Pages: |
567-75 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
714
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Elliott RW |
| Year: |
1990 |
| Journal: |
Genomics |
| Title: |
Localization of the rhodopsin gene to the distal half of mouse chromosome 6. |
| Volume: |
6 |
| Issue: |
4 |
| Pages: |
635-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pinto LH |
| Year: |
2005 |
| Journal: |
Vis Neurosci |
| Title: |
Generation, characterization, and molecular cloning of the Noerg-1 mutation of rhodopsin in the mouse. |
| Volume: |
22 |
| Issue: |
5 |
| Pages: |
619-29 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kunte MM |
| Year: |
2012 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
ER stress is involved in T17M rhodopsin-induced retinal degeneration. |
| Volume: |
53 |
| Issue: |
7 |
| Pages: |
3792-800 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liang Y |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
Rhodopsin signaling and organization in heterozygote rhodopsin knockout mice. |
| Volume: |
279 |
| Issue: |
46 |
| Pages: |
48189-96 |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Arango-Gonzalez B |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration. |
| Volume: |
9 |
| Issue: |
11 |
| Pages: |
e112142 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He F |
| Year: |
2016 |
| Journal: |
Sci Rep |
| Title: |
Phosphatidylinositol-3-phosphate is light-regulated and essential for survival in retinal rods. |
| Volume: |
6 |
|
| Pages: |
26978 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Leinonen H |
| Year: |
2022 |
| Journal: |
eNeuro |
| Title: |
Visual System Hyperexcitability and Compromised V1 Receptive Field Properties in Early-Stage Retinitis Pigmentosa in Mice. |
| Volume: |
9 |
| Issue: |
3 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ozaki E |
| Year: |
2020 |
| Journal: |
Life Sci Alliance |
| Title: |
SARM1 deficiency promotes rod and cone photoreceptor cell survival in a model of retinal degeneration. |
| Volume: |
3 |
| Issue: |
5 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Comitato A |
| Year: |
2020 |
| Journal: |
Mol Neurobiol |
| Title: |
Calpain Activation Is the Major Cause of Cell Death in Photoreceptors Expressing a Rhodopsin Misfolding Mutation. |
| Volume: |
57 |
| Issue: |
2 |
| Pages: |
589-599 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Glushakova LG |
| Year: |
2006 |
| Journal: |
Mol Vis |
| Title: |
Does recombinant adeno-associated virus-vectored proximal region of mouse rhodopsin promoter support only rod-type specific expression in vivo? |
| Volume: |
12 |
|
| Pages: |
298-309 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Charish J |
| Year: |
2020 |
| Journal: |
J Clin Invest |
| Title: |
Neogenin neutralization prevents photoreceptor loss in inherited retinal degeneration. |
| Volume: |
130 |
| Issue: |
4 |
| Pages: |
2054-2068 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ortega JT |
| Year: |
2022 |
| Journal: |
Hum Mol Genet |
| Title: |
Chromenone derivatives as novel pharmacological chaperones for retinitis pigmentosa-linked rod opsin mutants. |
| Volume: |
31 |
| Issue: |
20 |
| Pages: |
3439-3457 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sakami S |
| Year: |
2014 |
| Journal: |
Hum Mol Genet |
| Title: |
P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis. |
| Volume: |
23 |
| Issue: |
7 |
| Pages: |
1723-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yao J |
| Year: |
2018 |
| Journal: |
Autophagy |
| Title: |
Inhibiting autophagy reduces retinal degeneration caused by protein misfolding. |
| Volume: |
14 |
| Issue: |
7 |
| Pages: |
1226-1238 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Destaing O |
| Year: |
2005 |
| Journal: |
J Cell Sci |
| Title: |
A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts. |
| Volume: |
118 |
| Issue: |
Pt 13 |
| Pages: |
2901-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guilluy C |
| Year: |
2010 |
| Journal: |
Nat Med |
| Title: |
The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure. |
| Volume: |
16 |
| Issue: |
2 |
| Pages: |
183-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Comitato A |
| Year: |
2014 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Activation of Bax in three models of retinitis pigmentosa. |
| Volume: |
55 |
| Issue: |
6 |
| Pages: |
3555-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ortega JT |
| Year: |
2023 |
| Journal: |
Pharmacol Res |
| Title: |
Galanin receptor 3 - A new pharmacological target in retina degeneration. |
| Volume: |
188 |
|
| Pages: |
106675 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tanimoto N |
| Year: |
2014 |
| Journal: |
Doc Ophthalmol |
| Title: |
Auditory event-related signals in mouse ERG recordings. |
| Volume: |
128 |
| Issue: |
1 |
| Pages: |
25-32 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
648
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kerloch T |
| Year: |
2021 |
| Journal: |
Mol Psychiatry |
| Title: |
The atypical Rho GTPase Rnd2 is critical for dentate granule neuron development and anxiety-like behavior during adult but not neonatal neurogenesis. |
| Volume: |
26 |
| Issue: |
12 |
| Pages: |
7280-7295 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao C |
| Year: |
2003 |
| Journal: |
J Biol Chem |
| Title: |
GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2. |
| Volume: |
278 |
| Issue: |
36 |
| Pages: |
34641-53 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
425
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
987
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baehr W |
| Year: |
1988 |
| Journal: |
FEBS Lett |
| Title: |
Isolation and analysis of the mouse opsin gene. |
| Volume: |
238 |
| Issue: |
2 |
| Pages: |
253-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
al-Ubaidi MR |
| Year: |
1990 |
| Journal: |
J Biol Chem |
| Title: |
Mouse opsin. Gene structure and molecular basis of multiple transcripts. |
| Volume: |
265 |
| Issue: |
33 |
| Pages: |
20563-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Humphries MM |
| Year: |
1997 |
| Journal: |
Nat Genet |
| Title: |
Retinopathy induced in mice by targeted disruption of the rhodopsin gene. |
| Volume: |
15 |
| Issue: |
2 |
| Pages: |
216-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hollingsworth TJ |
| Year: |
2013 |
| Journal: |
J Biol Chem |
| Title: |
The severe autosomal dominant retinitis pigmentosa rhodopsin mutant Ter349Glu mislocalizes and induces rapid rod cell death. |
| Volume: |
288 |
| Issue: |
40 |
| Pages: |
29047-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Olsson JE |
| Year: |
1992 |
| Journal: |
Neuron |
| Title: |
Transgenic mice with a rhodopsin mutation (Pro23His): a mouse model of autosomal dominant retinitis pigmentosa. |
| Volume: |
9 |
| Issue: |
5 |
| Pages: |
815-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McNally N |
| Year: |
1999 |
| Journal: |
Hum Mol Genet |
| Title: |
Structural and functional rescue of murine rod photoreceptors by human rhodopsin transgene. |
| Volume: |
8 |
| Issue: |
7 |
| Pages: |
1309-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Butler MC |
| Year: |
2015 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
A Novel, Real-Time, In Vivo Mouse Retinal Imaging System. |
| Volume: |
56 |
| Issue: |
12 |
| Pages: |
7159-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jaissle GB |
| Year: |
2001 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Evaluation of the rhodopsin knockout mouse as a model of pure cone function. |
| Volume: |
42 |
| Issue: |
2 |
| Pages: |
506-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawamura S |
| Year: |
2012 |
| Journal: |
J Biol Chem |
| Title: |
Structural, energetic, and mechanical perturbations in rhodopsin mutant that causes congenital stationary night blindness. |
| Volume: |
287 |
| Issue: |
26 |
| Pages: |
21826-35 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xiao J |
| Year: |
2019 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Visual Contrast Sensitivity Correlates to the Retinal Degeneration in Rhodopsin Knockout Mice. |
| Volume: |
60 |
| Issue: |
13 |
| Pages: |
4196-4204 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ma J |
| Year: |
2011 |
| Journal: |
Mol Vis |
| Title: |
Combining chondroitinase ABC and growth factors promotes the integration of murine retinal progenitor cells transplanted into Rho(-/-) mice. |
| Volume: |
17 |
|
| Pages: |
1759-70 |
|
•
•
•
•
•
|
| Publication |
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Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes. |
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