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Search results 201 to 300 out of 431 for Rictor

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Type Details Score
Publication
First Author: Guo R
Year: 2023
Journal: Int Immunopharmacol
Title: Depletion of mTOR ameliorates CD(4)(+) T cell pyroptosis by promoting autophagy activity in septic mice.
Volume: 124
Issue: Pt B
Pages: 110964
Publication
First Author: Cho SH
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Hypoxia-inducible factors in CD4+ T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity.
Volume: 116
Issue: 18
Pages: 8975-8984
Publication
First Author: Liang Z
Year: 2018
Journal: Autophagy
Title: MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance.
Volume: 14
Issue: 3
Pages: 505-517
Publication
First Author: Lee K
Year: 2012
Journal: J Exp Med
Title: Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia.
Volume: 209
Issue: 4
Pages: 713-28
Publication
First Author: Lee K
Year: 2010
Journal: Immunity
Title: Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways.
Volume: 32
Issue: 6
Pages: 743-53
Publication
First Author: Chimin P
Year: 2017
Journal: J Lipid Res
Title: Adipocyte mTORC1 deficiency promotes adipose tissue inflammation and NLRP3 inflammasome activation via oxidative stress and de novo ceramide synthesis.
Volume: 58
Issue: 9
Pages: 1797-1807
Publication    
First Author: McCabe MP
Year: 2020
Journal: Elife
Title: Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission.
Volume: 9
Publication
First Author: Betz C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Feature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology.
Volume: 110
Issue: 31
Pages: 12526-34
Publication
First Author: Tao R
Year: 2015
Journal: Diabetes
Title: Sestrin 3 protein enhances hepatic insulin sensitivity by direct activation of the mTORC2-Akt signaling.
Volume: 64
Issue: 4
Pages: 1211-23
Publication
First Author: Newton RH
Year: 2018
Journal: Nat Immunol
Title: Maintenance of CD4 T cell fitness through regulation of Foxo1.
Volume: 19
Issue: 8
Pages: 838-848
Publication
First Author: Yang K
Year: 2013
Journal: Immunity
Title: T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming.
Volume: 39
Issue: 6
Pages: 1043-56
Publication
First Author: Werlen G
Year: 2022
Journal: Nat Commun
Title: Dietary glucosamine overcomes the defects in αβ-T cell ontogeny caused by the loss of de novo hexosamine biosynthesis.
Volume: 13
Issue: 1
Pages: 7404
Publication
First Author: Monteiro LB
Year: 2022
Journal: Diabetes
Title: Leptin Signaling Suppression in Macrophages Improves Immunometabolic Outcomes in Obesity.
Volume: 71
Issue: 7
Pages: 1546-1561
Publication
First Author: Menk AV
Year: 2018
Journal: Cell Rep
Title: Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions.
Volume: 22
Issue: 6
Pages: 1509-1521
Publication
First Author: Pollizzi KN
Year: 2015
Journal: J Clin Invest
Title: mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.
Volume: 125
Issue: 5
Pages: 2090-108
Publication
First Author: Delgoffe GM
Year: 2011
Journal: Nat Immunol
Title: The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.
Volume: 12
Issue: 4
Pages: 295-303
Publication
First Author: Romanino K
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function.
Volume: 108
Issue: 51
Pages: 20808-13
Publication
First Author: Gödel M
Year: 2011
Journal: J Clin Invest
Title: Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.
Volume: 121
Issue: 6
Pages: 2197-209
Publication  
First Author: Wu T
Year: 2016
Journal: Sci Rep
Title: mTOR masters monocytic myeloid-derived suppressor cells in mice with allografts or tumors.
Volume: 6
Pages: 20250
Publication
First Author: Wang H
Year: 2019
Journal: Virulence
Title: T-cell-specific mTOR deletion in mice ameliorated CD4+ T-cell survival in lethal sepsis induced by severe invasive candidiasis.
Volume: 10
Issue: 1
Pages: 892-901
Publication
First Author: Grahammer F
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress.
Volume: 111
Issue: 27
Pages: E2817-26
Publication
First Author: Limon JJ
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition.
Volume: 111
Issue: 47
Pages: E5076-85
Publication    
First Author: Kosillo P
Year: 2022
Journal: Elife
Title: Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2.
Volume: 11
Publication  
First Author: Baffi TR
Year: 2021
Journal: Sci Signal
Title: mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif.
Volume: 14
Issue: 678
Publication
First Author: Ou YH
Year: 2011
Journal: Mol Cell
Title: TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation.
Volume: 41
Issue: 4
Pages: 458-70
Publication
First Author: Deng J
Year: 2021
Journal: Nat Commun
Title: The metabolic hormone leptin promotes the function of T(FH) cells and supports vaccine responses.
Volume: 12
Issue: 1
Pages: 3073
Publication
First Author: Bai X
Year: 2021
Journal: Cell Rep
Title: Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation.
Volume: 36
Issue: 10
Pages: 109659
Publication  
First Author: Byles V
Year: 2013
Journal: Nat Commun
Title: The TSC-mTOR pathway regulates macrophage polarization.
Volume: 4
Pages: 2834
Publication
First Author: Kersten K
Year: 2023
Journal: Cell Rep
Title: Uptake of tumor-derived microparticles induces metabolic reprogramming of macrophages in the early metastatic lung.
Volume: 42
Issue: 6
Pages: 112582
Publication
First Author: Kalaitzidis D
Year: 2012
Journal: Cell Stem Cell
Title: mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis.
Volume: 11
Issue: 3
Pages: 429-39
Publication
First Author: Xu W
Year: 2023
Journal: Cell Rep
Title: Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells.
Volume: 42
Issue: 5
Pages: 112529
Publication
First Author: Robitaille AM
Year: 2013
Journal: Science
Title: Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis.
Volume: 339
Issue: 6125
Pages: 1320-3
Publication
First Author: Wang Y
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Tuberous sclerosis 1 (Tsc1)-dependent metabolic checkpoint controls development of dendritic cells.
Volume: 110
Issue: 50
Pages: E4894-903
Publication
First Author: Saucisse N
Year: 2021
Journal: Cell Rep
Title: Functional heterogeneity of POMC neurons relies on mTORC1 signaling.
Volume: 37
Issue: 2
Pages: 109800
Publication
First Author: Van de Velde LA
Year: 2017
Journal: J Biol Chem
Title: T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions.
Volume: 292
Issue: 1
Pages: 15-30
Publication
First Author: Zhao Y
Year: 2021
Journal: Gastroenterology
Title: mTORC1 and mTORC2 Converge on the Arp2/3 Complex to Promote KrasG12D-Induced Acinar-to-Ductal Metaplasia and Early Pancreatic Carcinogenesis.
Volume: 160
Issue: 5
Pages: 1755-1770.e17
Publication
First Author: Karalis V
Year: 2022
Journal: Nat Commun
Title: Raptor downregulation rescues neuronal phenotypes in mouse models of Tuberous Sclerosis Complex.
Volume: 13
Issue: 1
Pages: 4665
Publication
First Author: Zhang C
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor.
Volume: 307
Issue: 3
Pages: E305-15
Publication
First Author: Zhao Y
Year: 2018
Journal: Blood
Title: mTOR masters monocyte development in bone marrow by decreasing the inhibition of STAT5 on IRF8.
Volume: 131
Issue: 14
Pages: 1587-1599
Publication
First Author: Sato R
Year: 2018
Journal: Nat Immunol
Title: Combating herpesvirus encephalitis by potentiating a TLR3-mTORC2 axis.
Volume: 19
Issue: 10
Pages: 1071-1082
Publication  
First Author: Gupta A
Year: 2023
Journal: Int J Mol Sci
Title: mTORC1 Deficiency Prevents the Development of MC903-Induced Atopic Dermatitis through the Downregulation of Type 2 Inflammation.
Volume: 24
Issue: 6
Publication
First Author: Laplante M
Year: 2012
Journal: Cell
Title: mTOR signaling in growth control and disease.
Volume: 149
Issue: 2
Pages: 274-93
Publication
First Author: Lamouille S
Year: 2012
Journal: J Cell Sci
Title: TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion.
Volume: 125
Issue: Pt 5
Pages: 1259-73
Publication
First Author: Akgül S
Year: 2018
Journal: Cell Rep
Title: Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma.
Volume: 24
Issue: 2
Pages: 463-478.e5
Publication
First Author: Takai H
Year: 2010
Journal: Genes Dev
Title: Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
Volume: 24
Issue: 18
Pages: 2019-30
Publication
First Author: Gan X
Year: 2012
Journal: Nat Cell Biol
Title: PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12.
Volume: 14
Issue: 7
Pages: 686-96
Publication
First Author: Kohnke S
Year: 2021
Journal: Cell Rep
Title: Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence.
Volume: 36
Issue: 2
Pages: 109362
Publication
First Author: Sun F
Year: 2020
Journal: Cell Rep
Title: Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.
Volume: 30
Issue: 6
Pages: 1835-1847.e9
Publication
First Author: Signer RA
Year: 2014
Journal: Nature
Title: Haematopoietic stem cells require a highly regulated protein synthesis rate.
Volume: 509
Issue: 7498
Pages: 49-54
Publication
First Author: Hertzler-Schaefer K
Year: 2014
Journal: Cell Rep
Title: Pten loss induces autocrine FGF signaling to promote skin tumorigenesis.
Volume: 6
Issue: 5
Pages: 818-26
Publication
First Author: Fu X
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Activation of Rictor/mTORC2 signaling acts as a pivotal strategy to protect against sensorineural hearing loss.
Volume: 119
Issue: 10
Pages: e2107357119
Publication  
First Author: Yang M
Year: 2016
Journal: Nat Commun
Title: NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Volume: 7
Pages: 12730
Publication
First Author: Zeng H
Year: 2013
Journal: Nature
Title: mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function.
Volume: 499
Issue: 7459
Pages: 485-90
Publication
First Author: Shrestha S
Year: 2015
Journal: Nat Immunol
Title: Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.
Volume: 16
Issue: 2
Pages: 178-87
Publication
First Author: Zeng H
Year: 2018
Journal: Sci Adv
Title: Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.
Volume: 4
Issue: 1
Pages: eaar5701
Publication  
First Author: Zhu L
Year: 2014
Journal: Nat Commun
Title: TSC1 controls macrophage polarization to prevent inflammatory disease.
Volume: 5
Pages: 4696
Publication
First Author: Cai Y
Year: 2019
Journal: Cell Rep
Title: Differential Roles of the mTOR-STAT3 Signaling in Dermal γδ T Cell Effector Function in Skin Inflammation.
Volume: 27
Issue: 10
Pages: 3034-3048.e5
Publication
First Author: Huang SC
Year: 2016
Journal: Immunity
Title: Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation.
Volume: 45
Issue: 4
Pages: 817-830
Publication
First Author: Harada Y
Year: 2022
Journal: iScience
Title: Intracellular metabolic adaptation of intraepithelial CD4+CD8αα+ T lymphocytes.
Volume: 25
Issue: 4
Pages: 104021
Publication
First Author: Karmaus PWF
Year: 2017
Journal: J Exp Med
Title: Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis.
Volume: 214
Issue: 9
Pages: 2629-2647
Publication    
First Author: Cullen ER
Year: 2024
Journal: Elife
Title: Hyperactivity of mTORC1- and mTORC2-dependent signaling mediates epilepsy downstream of somatic PTEN loss.
Volume: 12
Publication
First Author: Moloughney JG
Year: 2016
Journal: Mol Cell
Title: mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1.
Volume: 63
Issue: 5
Pages: 811-26
Publication
First Author: Liu L
Year: 2020
Journal: Blood
Title: ER-associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity.
Volume: 136
Issue: 26
Pages: 2975-2986
Publication
First Author: Lee D
Year: 2014
Journal: Stem Cell Reports
Title: Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors.
Volume: 3
Issue: 5
Pages: 832-40
Publication
First Author: Liu P
Year: 2014
Journal: Nature
Title: Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus.
Volume: 508
Issue: 7497
Pages: 541-5
Publication
First Author: Guri Y
Year: 2017
Journal: Cancer Cell
Title: mTORC2 Promotes Tumorigenesis via Lipid Synthesis.
Volume: 32
Issue: 6
Pages: 807-823.e12
Publication
First Author: Tao H
Year: 2021
Journal: Nat Commun
Title: Differential controls of MAIT cell effector polarization by mTORC1/mTORC2 via integrating cytokine and costimulatory signals.
Volume: 12
Issue: 1
Pages: 2029
Publication
First Author: Mills JR
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: mTORC1 promotes survival through translational control of Mcl-1.
Volume: 105
Issue: 31
Pages: 10853-8
Publication
First Author: Liu C
Year: 2021
Journal: Sci Adv
Title: Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt.
Volume: 7
Issue: 41
Pages: eabg6262
Publication
First Author: Wang Y
Year: 2023
Journal: iScience
Title: Natural γδT17 cell development and functional acquisition is governed by the mTORC2-c-Maf-controlled mitochondrial fission pathway.
Volume: 26
Issue: 5
Pages: 106630
Publication
First Author: McGuire VA
Year: 2013
Journal: Mol Cell Biol
Title: Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling.
Volume: 33
Issue: 21
Pages: 4152-65
Publication
First Author: Yilmaz ÖH
Year: 2012
Journal: Nature
Title: mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.
Volume: 486
Issue: 7404
Pages: 490-5
Publication
First Author: Martinez-Lopez N
Year: 2023
Journal: Nat Cell Biol
Title: mTORC2-NDRG1-CDC42 axis couples fasting to mitochondrial fission.
Volume: 25
Issue: 7
Pages: 989-1003
Publication
First Author: Xie X
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: IkappaB kinase epsilon and TANK-binding kinase 1 activate AKT by direct phosphorylation.
Volume: 108
Issue: 16
Pages: 6474-9
Publication
First Author: Martinez Calejman C
Year: 2020
Journal: Nat Commun
Title: mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis.
Volume: 11
Issue: 1
Pages: 575
Publication
First Author: Li T
Year: 2019
Journal: Protein Cell
Title: PKM2 coordinates glycolysis with mitochondrial fusion and oxidative phosphorylation.
Volume: 10
Issue: 8
Pages: 583-594
Publication
First Author: Facchinetti V
Year: 2008
Journal: EMBO J
Title: The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C.
Volume: 27
Issue: 14
Pages: 1932-43
Publication
First Author: Ikenoue T
Year: 2008
Journal: EMBO J
Title: Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling.
Volume: 27
Issue: 14
Pages: 1919-31
Publication
First Author: Delgoffe GM
Year: 2009
Journal: Mol Immunol
Title: Enhanced interaction between Hsp90 and raptor regulates mTOR signaling upon T cell activation.
Volume: 46
Issue: 13
Pages: 2694-8
Publication
First Author: Oh WJ
Year: 2010
Journal: EMBO J
Title: mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide.
Volume: 29
Issue: 23
Pages: 3939-51
Publication
First Author: Jacinto E
Year: 2004
Journal: Nat Cell Biol
Title: Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
Volume: 6
Issue: 11
Pages: 1122-8
Publication
First Author: Venkatesh A
Year: 2015
Journal: J Clin Invest
Title: Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice.
Volume: 125
Issue: 4
Pages: 1446-58
Publication
First Author: Wu CC
Year: 2017
Journal: Dev Cell
Title: mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma.
Volume: 43
Issue: 6
Pages: 673-688.e5
Publication
First Author: Xu L
Year: 2017
Journal: Immunity
Title: The Kinase mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells.
Volume: 47
Issue: 3
Pages: 538-551.e5
Publication  
First Author: Raynor JL
Year: 2020
Journal: J Exp Med
Title: Hippo/Mst signaling coordinates cellular quiescence with terminal maturation in iNKT cell development and fate decisions.
Volume: 217
Issue: 6
Publication
First Author: Green RM
Year: 2017
Journal: Nat Commun
Title: Developmental nonlinearity drives phenotypic robustness.
Volume: 8
Issue: 1
Pages: 1970
Publication
First Author: Nobs SP
Year: 2015
Journal: Immunity
Title: PI3-Kinase-γ Has a Distinct and Essential Role in Lung-Specific Dendritic Cell Development.
Volume: 43
Issue: 4
Pages: 674-89
Publication    
First Author: Porter SN
Year: 2016
Journal: Elife
Title: Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations.
Volume: 5
Publication
First Author: Smithson LJ
Year: 2016
Journal: Genes Dev
Title: Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival.
Volume: 30
Issue: 12
Pages: 1383-8
Publication
First Author: Sinclair C
Year: 2017
Journal: Science
Title: mTOR regulates metabolic adaptation of APCs in the lung and controls the outcome of allergic inflammation.
Volume: 357
Issue: 6355
Pages: 1014-1021
Publication
First Author: Rosenlehner T
Year: 2024
Journal: Sci Signal
Title: Reciprocal regulation of mTORC1 signaling and ribosomal biosynthesis determines cell cycle progression in activated T cells.
Volume: 17
Issue: 859
Pages: eadi8753
Publication
First Author: Li M
Year: 2024
Journal: Cell Res
Title: AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine.
Volume: 34
Issue: 10
Pages: 683-706
Publication  
First Author: Miao L
Year: 2016
Journal: Elife
Title: mTORC1 is necessary but mTORC2 and GSK3β are inhibitory for AKT3-induced axon regeneration in the central nervous system.
Volume: 5
Pages: e14908
Publication  
First Author: Rion N
Year: 2019
Journal: Development
Title: mTOR controls embryonic and adult myogenesis via mTORC1.
Volume: 146
Issue: 7
Publication
First Author: Malik N
Year: 2019
Journal: Sci Rep
Title: mTORC1 activity is essential for erythropoiesis and B cell lineage commitment.
Volume: 9
Issue: 1
Pages: 16917
Publication
First Author: Babetto E
Year: 2020
Journal: Nat Neurosci
Title: A glycolytic shift in Schwann cells supports injured axons.
Volume: 23
Issue: 10
Pages: 1215-1228
Publication
First Author: Partovian C
Year: 2008
Journal: Mol Cell
Title: Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells.
Volume: 32
Issue: 1
Pages: 140-9
Publication  
First Author: Serra I
Year: 2022
Journal: Front Mol Neurosci
Title: Tsc1 Haploinsufficiency Leads to Pax2 Dysregulation in the Developing Murine Cerebellum.
Volume: 15
Pages: 831687
Publication
First Author: Zamfirescu RC
Year: 2021
Journal: Am J Physiol Cell Physiol
Title: mTORC1/2 signaling is downregulated by amino acid-free culture of mouse preimplantation embryos and is only partially restored by amino acid readdition.
Volume: 320
Issue: 1
Pages: C30-C44
Publication
First Author: Hasumi Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2.
Volume: 106
Issue: 44
Pages: 18722-7