|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 300 out of 702 for Ring1

0.03s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
GXD Expression
Probe: MGI:1101911
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:3688558
Age: embryonic day 10.5
Image: 3A
Note: Expression is in all neuroepithelia lining the ventricle.
Specimen Label: 3A
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3506606
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:2864323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539590
Age: embryonic day 15.5
Image: GUDMAP:13827
Specimen Label: GUDMAP:13827
Specimen Num: 4
GXD Expression  
Probe: MGI:3506606
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539590
Age: embryonic day 15.5
Image: GUDMAP:5942
Specimen Label: GUDMAP:5942
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506606
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539590
Age: embryonic day 15.5
Image: GUDMAP:12684
Specimen Label: GUDMAP:12684
Detected: true
Specimen Num: 3
Publication
First Author: Caron KM
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia.
Volume: 94
Issue: 21
Pages: 11540-5
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Protein
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: false
Publication
First Author: Sun X
Year: 2020
Journal: Br J Pharmacol
Title: Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys(44) to prevent cardiac structural damage in diabetic cardiomyopathy.
Volume: 177
Issue: 4
Pages: 836-856
Publication
First Author: Meng S
Year: 2016
Journal: Circ Res
Title: Transdifferentiation Requires iNOS Activation: Role of RING1A S-Nitrosylation.
Volume: 119
Issue: 9
Pages: e129-e138
Publication
First Author: del Mar Lorente M
Year: 2000
Journal: Development
Title: Loss- and gain-of-function mutations show a polycomb group function for Ring1A in mice.
Volume: 127
Issue: 23
Pages: 5093-100
Publication
First Author: Maezawa S
Year: 2017
Journal: Genes Dev
Title: Polycomb directs timely activation of germline genes in spermatogenesis.
Volume: 31
Issue: 16
Pages: 1693-1703
Publication
First Author: Blackledge NP
Year: 2014
Journal: Cell
Title: Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation.
Volume: 157
Issue: 6
Pages: 1445-1459
Publication
First Author: Cohen I
Year: 2021
Journal: Genes Dev
Title: Polycomb complexes redundantly maintain epidermal stem cell identity during development.
Volume: 35
Issue: 5-6
Pages: 354-366
Publication
First Author: Endoh M
Year: 2008
Journal: Development
Title: Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity.
Volume: 135
Issue: 8
Pages: 1513-24
Publication
First Author: Ikawa T
Year: 2016
Journal: Genes Dev
Title: Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program.
Volume: 30
Issue: 22
Pages: 2475-2485
Publication
First Author: Schoenfelder S
Year: 2015
Journal: Nat Genet
Title: Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome.
Volume: 47
Issue: 10
Pages: 1179-1186
Publication
First Author: Kondo T
Year: 2014
Journal: Dev Cell
Title: Polycomb potentiates meis2 activation in midbrain by mediating interaction of the promoter with a tissue-specific enhancer.
Volume: 28
Issue: 1
Pages: 94-101
Publication
First Author: Fielitz J
Year: 2007
Journal: J Clin Invest
Title: Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3.
Volume: 117
Issue: 9
Pages: 2486-95
Publication  
First Author: Piunti A
Year: 2014
Journal: Nat Commun
Title: Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication.
Volume: 5
Pages: 3649
Publication
First Author: Shima H
Year: 2018
Journal: Blood
Title: Ring1A and Ring1B inhibit expression of Glis2 to maintain murine MOZ-TIF2 AML stem cells.
Volume: 131
Issue: 16
Pages: 1833-1845
Publication
First Author: Rossi A
Year: 2016
Journal: Sci Adv
Title: Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice.
Volume: 2
Issue: 10
Pages: e1600972
Publication
First Author: Tsuboi M
Year: 2018
Journal: Dev Cell
Title: Ubiquitination-Independent Repression of PRC1 Targets during Neuronal Fate Restriction in the Developing Mouse Neocortex.
Volume: 47
Issue: 6
Pages: 758-772.e5
Publication
First Author: Li MY
Year: 2021
Journal: Dev Cell
Title: UV-induced reduction in Polycomb repression promotes epidermal pigmentation.
Volume: 56
Issue: 18
Pages: 2547-2561.e8
Publication
First Author: An Z
Year: 2018
Journal: Cell Rep
Title: Regulation of Mesenchymal Stem to Transit-Amplifying Cell Transition in the Continuously Growing Mouse Incisor.
Volume: 23
Issue: 10
Pages: 3102-3111
Publication
First Author: Jansz N
Year: 2018
Journal: Cell Rep
Title: Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway.
Volume: 25
Issue: 7
Pages: 1912-1923.e9
Publication
First Author: Du Z
Year: 2020
Journal: Mol Cell
Title: Polycomb Group Proteins Regulate Chromatin Architecture in Mouse Oocytes and Early Embryos.
Volume: 77
Issue: 4
Pages: 825-839.e7
Publication
First Author: Takano J
Year: 2022
Journal: Nat Commun
Title: PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment.
Volume: 13
Issue: 1
Pages: 7159
Publication
First Author: Ning B
Year: 2017
Journal: Nat Commun
Title: USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components.
Volume: 8
Issue: 1
Pages: 349
Publication
First Author: Fursova NA
Year: 2019
Journal: Mol Cell
Title: Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression.
Volume: 74
Issue: 5
Pages: 1020-1036.e8
Publication
First Author: Bruggeman SW
Year: 2005
Journal: Genes Dev
Title: Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.
Volume: 19
Issue: 12
Pages: 1438-43
Publication
First Author: Ren X
Year: 2011
Journal: Mol Cell Biol
Title: REST interacts with Cbx proteins and regulates polycomb repressive complex 1 occupancy at RE1 elements.
Volume: 31
Issue: 10
Pages: 2100-10
Publication
First Author: Chiacchiera F
Year: 2016
Journal: Cell Stem Cell
Title: Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity.
Volume: 18
Issue: 1
Pages: 91-103
Publication
First Author: Vogel T
Year: 2006
Journal: Dev Dyn
Title: Differential expression of polycomb repression complex 1 (PRC1) members in the developing mouse brain reveals multiple complexes.
Volume: 235
Issue: 9
Pages: 2574-85
Publication
First Author: Liang Q
Year: 2022
Journal: Dev Cell
Title: Essential role of MESP1-RING1A complex in cardiac differentiation.
Volume: 57
Issue: 22
Pages: 2533-2549.e7
Publication
First Author: Riising EM
Year: 2014
Journal: Mol Cell
Title: Gene silencing triggers polycomb repressive complex 2 recruitment to CpG islands genome wide.
Volume: 55
Issue: 3
Pages: 347-60
Publication
First Author: Suzuki M
Year: 2002
Journal: Development
Title: Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice.
Volume: 129
Issue: 18
Pages: 4171-83
Publication  
First Author: Yakushiji-Kaminatsui N
Year: 2018
Journal: Development
Title: Variant PRC1 competes with retinoic acid-related signals to repress Meis2 in the mouse distal forelimb bud.
Volume: 145
Issue: 19
Publication
First Author: Masui O
Year: 2023
Journal: Nat Cell Biol
Title: Polycomb repressive complexes 1 and 2 are each essential for maintenance of X inactivation in extra-embryonic lineages.
Volume: 25
Issue: 1
Pages: 134-144
Publication
First Author: Maezawa S
Year: 2023
Journal: Cell Death Dis
Title: PRC1 suppresses a female gene regulatory network to ensure testicular differentiation.
Volume: 14
Issue: 8
Pages: 501
Publication
First Author: Fujimura Y
Year: 2006
Journal: Development
Title: Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8.
Volume: 133
Issue: 12
Pages: 2371-81
Publication
First Author: Sánchez C
Year: 2007
Journal: Mol Cell Proteomics
Title: Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor.
Volume: 6
Issue: 5
Pages: 820-34
Protein
Organism: Mus musculus/domesticus
Length: 183  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 377  
Fragment?: false
Publication
First Author: Cohen I
Year: 2018
Journal: Cell Stem Cell
Title: PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification.
Volume: 22
Issue: 5
Pages: 726-739.e7
Publication
First Author: Bar C
Year: 2019
Journal: Cell Rep
Title: Polycomb Repressive Complex 1 Controls Maintenance of Fungiform Papillae by Repressing Sonic Hedgehog Expression.
Volume: 28
Issue: 1
Pages: 257-266.e5
Publication
First Author: Cohen I
Year: 2019
Journal: Genes Dev
Title: PRC1 preserves epidermal tissue integrity independently of PRC2.
Volume: 33
Issue: 1-2
Pages: 55-60
Publication
First Author: Puschendorf M
Year: 2008
Journal: Nat Genet
Title: PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos.
Volume: 40
Issue: 4
Pages: 411-20
Publication
First Author: Abe K
Year: 2004
Journal: Mamm Genome
Title: Gene content of the 750-kb critical region for mouse embryonic ectoderm lethal tcl-w5.
Volume: 15
Issue: 4
Pages: 265-76
Publication
First Author: Cho KW
Year: 2023
Journal: Circulation
Title: Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis.
Volume: 147
Issue: 24
Pages: 1823-1842
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication
First Author: Burton A
Year: 2013
Journal: Cell Rep
Title: Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.
Volume: 5
Issue: 3
Pages: 687-701
Publication
First Author: Allcock RJ
Year: 2000
Journal: Immunol Today
Title: The mouse as a model for the effects of MHC genes on human disease.
Volume: 21
Issue: 7
Pages: 328-32
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
Publication  
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
UniProt Feature
Begin: 1
Description: RING1 and YY1-binding protein
Type: chain
End: 228
UniProt Feature
Begin: 1
Description: E3 ubiquitin-protein ligase RING1
Type: chain
End: 406
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Publication
First Author: McGinty RK
Year: 2014
Journal: Nature
Title: Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome.
Volume: 514
Issue: 7524
Pages: 591-6
Protein Domain
Type: Domain
Description: RING1 is a transcriptional repressor associated with the Polycomb group (PcG) protein complex involved in stable repression of gene activity. It is a core component of polycomb repressive complex 1 (PRC1) that functions as an E3-ubuiquitin ligase that transferring the mono-ubuiquitin mark to the C-terminal tail of Histone H2A at K118/K119 []. PRC1 is also capable of chromatin compaction, a function not requiring histone tails, and this activity appears important in gene silencing []. RING1 interacts with multiple PcG proteins and displays tumorigenic activity[]. It also shows zinc-dependent DNA binding activity. Moreover, RING1 inhibits transactivation of the DNA-binding protein recombination signal binding protein-Jkappa (RBP-J) by Notch through interaction with the LIM domains of KyoT2 []. RING1 contains a C3HC4-type RING-HC finger [].
Publication
First Author: Danen-van Oorschot AA
Year: 2004
Journal: Cell Death Differ
Title: Human death effector domain-associated factor interacts with the viral apoptosis agonist Apoptin and exerts tumor-preferential cell killing.
Volume: 11
Issue: 5
Pages: 564-73
Publication  
First Author: He Z
Year: 2020
Journal: Genes (Basel)
Title: Ring 1 and YY1 Binding Protein Expressed in Murine Spermatocytes but Dispensable for Spermatogenesis.
Volume: 11
Issue: 1
Publication
First Author: Lin SS
Year: 2008
Journal: Plant J
Title: RING1 E3 ligase localizes to plasma membrane lipid rafts to trigger FB1-induced programmed cell death in Arabidopsis.
Volume: 56
Issue: 4
Pages: 550-61
Protein Domain
Type: Family
Description: Proteins included in this entry have an N-terminal RanBP2-type zinc finger and a Yaf2/RYBP C-terminal binding motif. Proteins with these regions include Yaf2 and RYBP proteins, which are homologous parts of the PRC1 complex [].RYBP is a zinc finger protein with an essential role during embryonic development, which binds transcriptional factors, Polycomb products, and mediators of apoptosisis []. RYBP also binds ubiquitin and Cbx proteins via the C-terminal docking module [, ]. RYBP is natively unstructured until it binds to the C-terminal region of the Polycomb protein Ring1B or to DNA []. Yaf2 binds to MYC and inhibits MYC-mediated transactivation [].
Pseudogene
Type: pseudogene
Organism: Mus caroli
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory