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Search results 201 to 258 out of 258 for Rnd3

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein
Q68FH0
Organism: Mus musculus/domesticus
Length: 1190  
Fragment?: false
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Protein
Q9JHJ0
Organism: Mus musculus/domesticus
Length: 352  
Fragment?: false
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Protein
Q99ME2
Organism: Mus musculus/domesticus
Length: 1125  
Fragment?: false
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Protein
E9PW37
Organism: Mus musculus/domesticus
Length: 1286  
Fragment?: false
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Protein Coding Gene
MGI:104627 | Dst
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2444926 | Ckap4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:103309 | Flot2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1332637 | Arhgap5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109611 | Dsp
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:103190 | Muc13
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:94930 | Dsg1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1860078 | Txnl1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1918685 | Arhgap21
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95278 | Epha2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2652860 | Plekhg5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:103293 | Ptpn13
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1343044 | Rbmx
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q8BMK4
Organism: Mus musculus/domesticus
Length: 575  
Fragment?: false
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Protein
E9Q557
Organism: Mus musculus/domesticus
Length: 2883  
Fragment?: false
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Protein
Q9WV02
Organism: Mus musculus/domesticus
Length: 391  
Fragment?: false
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Protein
Q66T02
Organism: Mus musculus/domesticus
Length: 1073  
Fragment?: false
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Protein
Q91ZU6
Organism: Mus musculus/domesticus
Length: 7393  
Fragment?: false
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Protein
Q60634
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: false
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Protein
Q61495
Organism: Mus musculus/domesticus
Length: 1057  
Fragment?: false
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Protein
Q03145
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
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Protein
P97393
Organism: Mus musculus/domesticus
Length: 1501  
Fragment?: false
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Protein
Q6DFV3
Organism: Mus musculus/domesticus
Length: 1944  
Fragment?: false
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Protein
P19467
Organism: Mus musculus/domesticus
Length: 573  
Fragment?: false
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Protein
Q64512
Organism: Mus musculus/domesticus
Length: 2453  
Fragment?: false
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Protein
Q8CDN6
Organism: Mus musculus/domesticus
Length: 289  
Fragment?: false
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Protein Coding Gene
MGI:2145425 | Depdc1b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109153 | Ktn1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2159344 | Vangl1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q80Z96
Organism: Mus musculus/domesticus
Length: 526  
Fragment?: false
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Protein
Q61595
Organism: Mus musculus/domesticus
Length: 1327  
Fragment?: false
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Protein
Q8BH88
Organism: Mus musculus/domesticus
Length: 529  
Fragment?: false
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Protein Coding Gene
MGI:107927 | Rock1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2157953 | Rbm39
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1929494 | Arhgap35
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q8VH51
Organism: Mus musculus/domesticus
Length: 530  
Fragment?: false
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Protein
P70335
Organism: Mus musculus/domesticus
Length: 1354  
Fragment?: false
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Protein
Q91YM2
Organism: Mus musculus/domesticus
Length: 1499  
Fragment?: false
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Publication
15775972 | -
First Author: Riento K
Year: 2005
Journal: EMBO J
Title: RhoE function is regulated by ROCK I-mediated phosphorylation.
Volume: 24
Issue: 6
Pages: 1170-80
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Publication
15754346 | -
First Author: Bektic J
Year: 2005
Journal: Prostate
Title: Small G-protein RhoE is underexpressed in prostate cancer and induces cell cycle arrest and apoptosis.
Volume: 64
Issue: 4
Pages: 332-40
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Publication
15777789 | -
First Author: Rubenstein NM
Year: 2005
Journal: Exp Cell Res
Title: Rnd3/RhoE induces tight junction formation in mammary epithelial tumor cells.
Volume: 305
Issue: 1
Pages: 74-82
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Publication
9671486 | -
First Author: Guasch RM
Year: 1998
Journal: Mol Cell Biol
Title: RhoE regulates actin cytoskeleton organization and cell migration.
Volume: 18
Issue: 8
Pages: 4761-71
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Protein Domain
IPR041843 | RhoE
Type: Family
Description: The Rnd proteins, which form a distinct sub-group of the Rho family of small GTP-binding proteins, have been shown to regulate the organization of the actin cytoskeleton in several tissues []. This entry represents RhoE (also known as Rnd3 or Rho8), which is a member of the Rnd subfamily. Unlike other small G proteins, RhoE, along with two other proteins Rnd1/Rho6 and Rnd2/RhoN, does not hydrolyze GTP []. This is due to changes in key amino acids involved in catalysing GTP hydrolysis []. RhoE is known to bind the serine-threonine kinase ROCK I. Unphosphorylated RhoE associates primarily with membranes, but ROCK I-phosphorylated RhoE localizes in the cytosol []. Phosphorylation of RhoE correlates with its activity in disrupting RhoA-induced stress fibres and inhibiting Ras-induced fibroblast transformation []. In mammary epithelial tumor cells, RhoE regulates the assembly of the apical junction complex and tight junction formation []. In cells that lack stress fibres, such as macrophages and monocytes, RhoE induces a redistribution of actin, causing morphological changes in the cell []. In addition, RhoE has been shown to inhibit cell cycle progression in G1 phase at a point upstream of the pRb family pocket protein checkpoint []. RhoE has also been shown to inhibit Ras- and Raf-induced fibroblast transformation. RhoE is underexpressed in prostate cancer cells both in vitro and in vivo; re-expression of RhoE suppresses cell cycle progression and increases apoptosis, suggesting it may play a role in tumor suppression [].
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Publication
11940653 | J:78928
First Author: Katoh H
Year: 2002
Journal: Mol Cell Biol
Title: Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers.
Volume: 22
Issue: 9
Pages: 2952-64
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Publication
26969432 | J:231580
 
First Author: Gladwyn-Ng I
Year: 2016
Journal: Neural Dev
Title: Bacurd1/Kctd13 and Bacurd2/Tnfaip1 are interacting partners to Rnd proteins which influence the long-term positioning and dendritic maturation of cerebral cortical neurons.
Volume: 11
Pages: 7
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Protein Coding Gene
MGI:102709 | Cav1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P49817
Organism: Mus musculus/domesticus
Length: 178  
Fragment?: false
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Protein Coding Gene
MGI:1098772 | Pik3r2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
O08908
Organism: Mus musculus/domesticus
Length: 722  
Fragment?: false
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Publication
12009891 | -
First Author: Garavini H
Year: 2002
Journal: Biochemistry
Title: Crystal structure of the core domain of RhoE/Rnd3: a constitutively activated small G protein.
Volume: 41
Issue: 20
Pages: 6303-10
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Publication
16042565 | -
First Author: Riento K
Year: 2005
Journal: Biochem Soc Trans
Title: Function and regulation of RhoE.
Volume: 33
Issue: Pt 4
Pages: 649-51
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Publication
16493413 | -
First Author: Chardin P
Year: 2006
Journal: Nat Rev Mol Cell Biol
Title: Function and regulation of Rnd proteins.
Volume: 7
Issue: 1
Pages: 54-62
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Protein Coding Gene
MGI:97583 | Pik3r1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P26450
Organism: Mus musculus/domesticus
Length: 724  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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