Type |
Details |
Score |
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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|
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•
•
•
•
•
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Publication |
First Author: |
Dabertrand F |
Year: |
2007 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Role of RYR3 splice variants in calcium signaling in mouse nonpregnant and pregnant myometrium. |
Volume: |
293 |
Issue: |
3 |
Pages: |
C848-54 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4863
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4834
 |
Fragment?: |
false |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Allele |
Name: |
ryanodine receptor 3; targeted mutation 1, Institute of Medical Science, Japan |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
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•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ryr3/Ryr3 |
Background: |
involves: 129P2/OlaHsd * C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
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•
•
•
•
•
|
Publication |
First Author: |
Cabra V |
Year: |
2016 |
Journal: |
Biophys J |
Title: |
Ultrastructural Analysis of Self-Associated RyR2s. |
Volume: |
110 |
Issue: |
12 |
Pages: |
2651-2662 |
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•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This SPRY domain is the first of three structural repeats in all three isoforms of the ryanodine receptor (RyR), which are the major Ca2+ release channels in the membranes of sarcoplasmic reticulum (SR) []. There are three RyR genes in mammals; the skeletal RyR1, the cardiac RyR2 and the brain RyR3 []. The three SPRY domains are located in the N-terminal part of the cytoplasmic region of the RyRs []. The first domain may be involved in RyR2 dimerization []. |
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•
•
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•
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Protein Domain |
Type: |
Domain |
Description: |
This SPRY domain is the third of three structural repeats in all three isoforms of the ryanodine receptor (RyR), which are the major Ca2+ release channels in the membranes of sarcoplasmic reticulum (SR) []. There are three RyR genes in mammals; the skeletal RyR1, the cardiac RyR2 and the brain RyR3 []. The three SPRY domains are located in the N-terminal part of the cytoplasmic region of the RyRs, but no specific function has been found for this third SPRY domain of the RyRs []. |
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•
•
•
•
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Publication |
First Author: |
Lanner JT |
Year: |
2010 |
Journal: |
Cold Spring Harb Perspect Biol |
Title: |
Ryanodine receptors: structure, expression, molecular details, and function in calcium release. |
Volume: |
2 |
Issue: |
11 |
Pages: |
a003996 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tae H |
Year: |
2009 |
Journal: |
Eur Biophys J |
Title: |
Ubiquitous SPRY domains and their role in the skeletal type ryanodine receptor. |
Volume: |
39 |
Issue: |
1 |
Pages: |
51-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marziali G |
Year: |
1996 |
Journal: |
FEBS Lett |
Title: |
cDNA cloning reveals a tissue specific expression of alternatively spliced transcripts of the ryanodine receptor type 3 (RyR3) calcium release channel. |
Volume: |
394 |
Issue: |
1 |
Pages: |
76-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakashima Y |
Year: |
1997 |
Journal: |
FEBS Lett |
Title: |
Molecular cloning and characterization of a human brain ryanodine receptor. |
Volume: |
417 |
Issue: |
1 |
Pages: |
157-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Torres RF |
Year: |
2017 |
Journal: |
Front Mol Neurosci |
Title: |
Mecp2 Mediates Experience-Dependent Transcriptional Upregulation of Ryanodine Receptor Type-3. |
Volume: |
10 |
|
Pages: |
188 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang KY |
Year: |
2024 |
Journal: |
Br J Pharmacol |
Title: |
Differential contributions of G protein- or arrestin subtype-mediated signalling underlie urocortin 3-induced somatostatin secretion in pancreatic δ cells. |
Volume: |
181 |
Issue: |
15 |
Pages: |
2600-2621 |
|
•
•
•
•
•
|
Publication |
First Author: |
Supnet C |
Year: |
2010 |
Journal: |
J Neurochem |
Title: |
Up-regulation of the type 3 ryanodine receptor is neuroprotective in the TgCRND8 mouse model of Alzheimer's disease. |
Volume: |
112 |
Issue: |
2 |
Pages: |
356-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wen N |
Year: |
2018 |
Journal: |
PLoS One |
Title: |
Deficiency of MTMR14 impairs male fertility in Mus musculus. |
Volume: |
13 |
Issue: |
11 |
Pages: |
e0206224 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fritz N |
Year: |
2007 |
Journal: |
J Cell Sci |
Title: |
RyR1-specific requirement for depolarization-induced Ca2+ sparks in urinary bladder smooth muscle. |
Volume: |
120 |
Issue: |
Pt 21 |
Pages: |
3784-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang W |
Year: |
2011 |
Journal: |
Exp Eye Res |
Title: |
Localization and phenotype-specific expression of ryanodine calcium release channels in C57BL6 and DBA/2J mouse strains. |
Volume: |
93 |
Issue: |
5 |
Pages: |
700-9 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
5035
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4966
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4868
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4966
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
5033
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4858
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
5061
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4888
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1020
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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•
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•
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