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Search results 201 to 260 out of 260 for Scd2

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0.094s
Type Details Score
GXD Expression
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1876522
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Note: Expression was strong in the immune system.
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1741222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3062605
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2757317
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5538967
Age: embryonic day 10.5
Image: GUDMAP:91
Specimen Label: GUDMAP:91
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754022
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Specimen Label: EH2751; Specimen C3324
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3599822
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3655216
Assay Type: RNA in situ
Annotation Date: 2006-09-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1737518
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3655396
Age: embryonic day 10.5
Specimen Label: 3B E10.5 Embryo
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3655216
Assay Type: RNA in situ
Annotation Date: 2006-09-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1737518
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3655396
Age: embryonic day 10.5
Specimen Label: 3B E10.5 Embryo (MM region)
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3062605
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5538967
Age: embryonic day 10.5
Image: GUDMAP:91
Specimen Label: GUDMAP:91
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3280922
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1833322
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3287022
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1821522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3557722
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1702122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1668822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757522
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1738322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1802422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3514216
Assay Type: RNA in situ
Annotation Date: 2005-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3514302
Age: embryonic day 13.0
Image: 1A E13.0
Note: Extensively expressed in other brain regions.
Specimen Label: 1A E13.0
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3514216
Assay Type: RNA in situ
Annotation Date: 2005-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:3514302
Age: embryonic day 17.0
Note: Extensively expressed in other brain regions.
Specimen Label: E17.0
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3514216
Assay Type: RNA in situ
Annotation Date: 2005-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3514302
Age: postnatal day 1
Image: 1A P1
Note: Extensively expressed in other brain regions.
Specimen Label: 1A P1
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Note: Expression was strong in the skull (base and vault).
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5310197
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423521
Age: embryonic day 14.5
Image: EH2751; Specimen C3324
Note: Expression was strong in whisker follicle.
Specimen Label: EH2751; Specimen C3324
Detected: true
Specimen Num: 1
Publication        
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Allele
Name: stearoyl-Coenzyme A desaturase 2; targeted mutation 2.1, Makoto Miyazaki
Allele Type: Targeted
Attribute String: Conditional ready
Publication
First Author: McMichael CM
Year: 2013
Journal: Plant Cell
Title: Mediation of clathrin-dependent trafficking during cytokinesis and cell expansion by Arabidopsis stomatal cytokinesis defective proteins.
Volume: 25
Issue: 10
Pages: 3910-25
Protein Domain
Type: Family
Description: This entry represents a group of plant proteins, including SCD2 from Arabidopsis. SCD2 (STOMATAL CYTOKINESIS DEFECTIVE 2) functions in clathrin-mediated membrane transport. In Arabidopsis, loss of SCD2 function disrupts cytokinesis and cell expansion and impairs fertility [].
Protein Domain
Type: Family
Description: This entry includes a group of fungal SH3 domain-containing proteins, including Bem1 from budding yeasts and Scd2 (Ral3) from fission yeasts. Bem1 (Bud emergence protein 1) is involved in establishing cell polarity and morphogenesis []. It interacts with Axl2 (required for axial budding in haploid cells) and forms a complex with Cdc42, Cdc24, and Cla4 []. Scd2 forms complexes with both scd1 and cdc42sp and is required for normal morphology and mating [].
Publication
First Author: Bender A
Year: 1991
Journal: Mol Cell Biol
Title: Use of a screen for synthetic lethal and multicopy suppressee mutants to identify two new genes involved in morphogenesis in Saccharomyces cerevisiae.
Volume: 11
Issue: 3
Pages: 1295-305
Publication
First Author: Chang EC
Year: 1994
Journal: Cell
Title: Cooperative interaction of S. pombe proteins required for mating and morphogenesis.
Volume: 79
Issue: 1
Pages: 131-41
Protein Domain
Type: Domain
Description: This entry represents the first SH3 domain found in budding yeast Bem1 and fission yeast Scd2.Bem1 (Bud emergence protein 1) is involved in establishing cell polarity and morphogenesis []. It interacts with Axl2 (required for axial budding in haploid cells) and forms a complex with Cdc42, Cdc24, and Cla4 [, ]. Scd2 forms complexes with both scd1 and cdc42sp and is required for normal morphology and mating [].
Protein Domain
Type: Domain
Description: This entry represents the second SH3 domain found in budding yeast Bem1 and fission yeast Scd2.Bem1 (Bud emergence protein 1) is involved in establishing cell polarity and morphogenesis []. It interacts with Axl2 (required for axial budding in haploid cells) and forms a complex with Cdc42, Cdc24, and Cla4 [, ]. Scd2 forms complexes with both scd1 and cdc42sp and is required for normal morphology and mating [].
Publication
First Author: Smith SE
Year: 2013
Journal: J Cell Biol
Title: Independence of symmetry breaking on Bem1-mediated autocatalytic activation of Cdc42.
Volume: 202
Issue: 7
Pages: 1091-106
Publication
First Author: Gao XD
Year: 2007
Journal: Mol Biol Cell
Title: Sequential and distinct roles of the cadherin domain-containing protein Axl2p in cell polarization in yeast cell cycle.
Volume: 18
Issue: 7
Pages: 2542-60
Publication
First Author: Stahelin RV
Year: 2007
Journal: J Biol Chem
Title: Structural and membrane binding analysis of the Phox homology domain of Bem1p: basis of phosphatidylinositol 4-phosphate specificity.
Volume: 282
Issue: 35
Pages: 25737-47
Protein Domain
Type: Domain
Description: This entry represents the phox homology (PX) domain found in budding yeast Bem1 and fission yeast Scd2. The PX domain is a phosphoinositide (PI) binding module present in many proteins with diverse functions such as cell signaling, vesicular trafficking, protein sorting, and lipid modification. The PX domain of Bem1 specifically binds phosphatidylinositol-4-phosphate (PI4P) [].Bem1 (Bud emergence protein 1) is involved in establishing cell polarity and morphogenesis []. It interacts with Axl2 (required for axial budding in haploid cells) and forms a complex with Cdc42, Cdc24, and Cla4 [, ]. Scd2 forms complexes with both scd1 and cdc42sp and is required for normal morphology and mating [].
Publication
First Author: Miyazaki M
Year: 2001
Journal: J Biol Chem
Title: Oleoyl-CoA is the major de novo product of stearoyl-CoA desaturase 1 gene isoform and substrate for the biosynthesis of the Harderian gland 1-alkyl-2,3-diacylglycerol.
Volume: 276
Issue: 42
Pages: 39455-61
Publication
First Author: Miyazaki M
Year: 2001
Journal: J Nutr
Title: Targeted disruption of stearoyl-CoA desaturase1 gene in mice causes atrophy of sebaceous and meibomian glands and depletion of wax esters in the eyelid.
Volume: 131
Issue: 9
Pages: 2260-8
Publication
First Author: Miyazaki M
Year: 2003
Journal: J Biol Chem
Title: Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors.
Volume: 278
Issue: 36
Pages: 33904-11
Publication
First Author: Chu K
Year: 2006
Journal: Mol Cell Biol
Title: Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation.
Volume: 26
Issue: 18
Pages: 6786-98
Publication
First Author: Li L
Year: 2013
Journal: PLoS One
Title: SCD1 Expression is dispensable for hepatocarcinogenesis induced by AKT and Ras oncogenes in mice.
Volume: 8
Issue: 9
Pages: e75104
Publication
First Author: Miyazaki M
Year: 2002
Journal: J Lipid Res
Title: Lack of stearoyl-CoA desaturase-1 function induces a palmitoyl-CoA Delta6 desaturase and represses the stearoyl-CoA desaturase-3 gene in the preputial glands of the mouse.
Volume: 43
Issue: 12
Pages: 2146-54
Publication
First Author: Garbay B
Year: 1997
Journal: Brain Res Dev Brain Res
Title: Acetyl-CoA carboxylase gene expression in the developing mouse brain. Comparison with other genes involved in lipid biosynthesis.
Volume: 98
Issue: 2
Pages: 197-203
Publication
First Author: Lai KKY
Year: 2017
Journal: Gastroenterology
Title: Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6.
Volume: 152
Issue: 6
Pages: 1477-1491