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Search results 201 to 293 out of 293 for Scgn

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827897
Age: embryonic day 14.5
Image: euxassay_002978_20
Specimen Label: euxassay_002978_20
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827898
Age: embryonic day 14.5
Image: euxassay_001144_06
Specimen Label: euxassay_001144_06
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827898
Age: embryonic day 14.5
Image: euxassay_001144_07
Specimen Label: euxassay_001144_07
Detected: true
Specimen Num: 5
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•
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•
GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827898
Age: embryonic day 14.5
Image: euxassay_001144_17
Specimen Label: euxassay_001144_17
Detected: true
Specimen Num: 15
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•
GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827898
Age: embryonic day 14.5
Image: euxassay_001144_18
Specimen Label: euxassay_001144_18
Detected: true
Specimen Num: 16
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•
GXD Expression
GXD Expression
 
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903827
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6491315
Age: postnatal newborn
Note: Expressing neurons are seen in the interstitial nucleus of the posterior limb of the anterior commissure (IPAC).
Specimen Label: 5A2
Detected: true
Specimen Num: 20
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•
GXD Expression
GXD Expression
 
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903827
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6491315
Age: postnatal newborn
Note: Expressing neurons are seen in the interstitial nucleus of the posterior limb of the anterior commissure (IPAC).
Specimen Label: 5A3
Detected: true
Specimen Num: 21
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•
GXD Expression
GXD Expression
 
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903827
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6491315
Age: postnatal newborn
Note: Expressing neurons are seen in the interstitial nucleus of the posterior limb of the anterior commissure (IPAC).
Specimen Label: 5A4
Detected: true
Specimen Num: 22
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•
GXD Expression
GXD Expression
 
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903827
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6491315
Age: postnatal newborn
Note: Expressing neurons are seen in the interstitial nucleus of the posterior limb of the anterior commissure (IPAC).
Specimen Label: 5A5
Detected: true
Specimen Num: 23
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•
GXD Expression
GXD Expression
 
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6491315
Age: postnatal adult
Note: Expression is seen in multipolar cells in the interstitial nucleus of the posterior limb of the anterior commissure (IPAC); they are not GABAergic.
Specimen Label: 7E1
Detected: true
Specimen Num: 32
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•
GXD Expression
GXD Expression
   
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3566627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6491315
Age: postnatal newborn
Specimen Label: 5A4
Detected: true
Specimen Num: 22
•
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3566627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6491315
Age: postnatal newborn
Specimen Label: 5A5
Detected: true
Specimen Num: 23
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3599823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827898
Age: embryonic day 14.5
Image: euxassay_001144_10
Specimen Label: euxassay_001144_10
Detected: true
Specimen Num: 8
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3599823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827898
Age: embryonic day 14.5
Image: euxassay_001144_11
Specimen Label: euxassay_001144_11
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3599823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827898
Age: embryonic day 14.5
Image: euxassay_001144_12
Specimen Label: euxassay_001144_12
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3599823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827898
Age: embryonic day 14.5
Image: euxassay_001144_13
Specimen Label: euxassay_001144_13
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3599823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827898
Age: embryonic day 14.5
Image: euxassay_001144_14
Specimen Label: euxassay_001144_14
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3599823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827897
Age: embryonic day 14.5
Image: euxassay_002978_10
Specimen Label: euxassay_002978_10
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3599823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827897
Age: embryonic day 14.5
Image: euxassay_002978_11
Specimen Label: euxassay_002978_11
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3599823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827897
Age: embryonic day 14.5
Image: euxassay_002978_12
Specimen Label: euxassay_002978_12
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3599823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827897
Age: embryonic day 14.5
Image: euxassay_002978_13
Specimen Label: euxassay_002978_13
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3599823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827897
Age: embryonic day 14.5
Image: euxassay_002978_14
Specimen Label: euxassay_002978_14
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2018-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6197051
Age: embryonic day 14.5
Specimen Label: S4I
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2018-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6197051
Age: embryonic day 14.5
Specimen Label: S4J
Detected: true
Specimen Num: 3
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:6197048
Assay Type: Immunohistochemistry
Annotation Date: 2018-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6197060
Age: embryonic day 13.5
Specimen Label: S4A/D
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280921
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6491315
Age: embryonic day 13.0
Note: Expression is seen in the olfactory bulb; double labeling shows these are GABAergic cells.
Specimen Label: 5C
Detected: true
Specimen Num: 26
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GXD Expression
GXD Expression
   
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6491315
Age: embryonic day 13.0
Specimen Label: 5C1
Detected: true
Specimen Num: 27
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:1627274
Assay Type: RNA in situ
Annotation Date: 2024-12-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7786477
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3520427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6491315
Age: postnatal newborn
Specimen Label: 5A5
Detected: true
Specimen Num: 23
•
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3520427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6491315
Age: postnatal newborn
Specimen Label: 5A6
Detected: true
Specimen Num: 24
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3520428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6491315
Age: postnatal adult
Note: Expression is seen in a subset of GABAergic neurons.
Specimen Label: 7E
Detected: true
Specimen Num: 31
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•
GXD Expression
GXD Expression
 
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3520427
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6491315
Age: postnatal newborn
Note: Expression is seen in GABAergic neurons.
Specimen Label: 5D1
Detected: true
Specimen Num: 29
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6491315
Age: postnatal adult
Specimen Label: 7B
Detected: true
Specimen Num: 30
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702121
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6491315
Age: embryonic day 13.0
Note: Expression is seen in putative enteroendocrine cells.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1738321
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6491315
Age: embryonic day 13.0
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6197048
Assay Type: Immunohistochemistry
Annotation Date: 2018-09-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3747121
Stage: TS21
Assay Id: MGI:6197060
Age: embryonic day 13.5
Specimen Label: S4A/D
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:6490647
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3791723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6491313
Age: embryonic day 15.0
Note: Expression is seen in the granular layer.
Specimen Label: S2C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6490647
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3791723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6491313
Age: embryonic day 15.0
Note: Expression is seen in the granular layer.
Specimen Label: S2C1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3791723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6491315
Age: embryonic day 15.0
Note: Expression is seen in the granular layer.
Specimen Label: 3E
Detected: true
Specimen Num: 11
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•
GXD Expression
GXD Expression
 
Probe: MGI:6490652
Assay Type: Immunohistochemistry
Annotation Date: 2021-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3791723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6491315
Age: embryonic day 15.0
Note: Expression is seen in the granular layer.
Specimen Label: 3E1
Detected: true
Specimen Num: 12
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Publication
28637794 | J:244668
First Author: Malenczyk K
Year: 2017
Journal: EMBO J
Title: A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover.
Volume: 36
Issue: 14
Pages: 2107-2125
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Publication
28223495 | J:241650
First Author: Hanics J
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Secretagogin-dependent matrix metalloprotease-2 release from neurons regulates neuroblast migration.
Volume: 114
Issue: 10
Pages: E2006-E2015
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Publication
27669410 | J:238093
   
First Author: Garas FN
Year: 2016
Journal: Elife
Title: Secretagogin expression delineates functionally-specialized populations of striatal parvalbumin-containing interneurons.
Volume: 5
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Publication
31144035 | J:277363
First Author: Zahola P
Year: 2019
Journal: Brain Struct Funct
Title: Secretagogin expression in the vertebrate brainstem with focus on the noradrenergic system and implications for Alzheimer's disease.
Volume: 224
Issue: 6
Pages: 2061-2078
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Publication
23430976 | J:199962
First Author: Hasegawa K
Year: 2013
Journal: FASEB J
Title: The hydrolase DDAH2 enhances pancreatic insulin secretion by transcriptional regulation of secretagogin through a Sirt1-dependent mechanism in mice.
Volume: 27
Issue: 6
Pages: 2301-15
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Publication
16939418 | J:117967
First Author: Rogstam A
Year: 2007
Journal: Biochem J
Title: Binding of calcium ions and SNAP-25 to the hexa EF-hand protein secretagogin.
Volume: 401
Issue: 1
Pages: 353-63
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Publication
30209240 | J:283858
 
First Author: Alpár A
Year: 2018
Journal: EMBO J
Title: Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress.
Volume: 37
Issue: 21
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Publication
24506885 | J:210169
First Author: Shinagawa T
Year: 2014
Journal: Cell Stem Cell
Title: Histone variants enriched in oocytes enhance reprogramming to induced pluripotent stem cells.
Volume: 14
Issue: 2
Pages: 217-27
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Publication
29910119 | J:264987
     
First Author: Malenczyk K
Year: 2018
Journal: Mol Metab
Title: Secretagogin protects Pdx1 from proteasomal degradation to control a transcriptional program required for β cell specification.
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Publication
24125957 | J:204690
First Author: Brzezinski JA 4th
Year: 2013
Journal: Dev Biol
Title: Blimp1 (Prdm1) prevents re-specification of photoreceptors into retinal bipolar cells by restricting competence.
Volume: 384
Issue: 2
Pages: 194-204
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Publication
36070775 | J:330584
First Author: Hamnett R
Year: 2022
Journal: Curr Biol
Title: Regional cytoarchitecture of the adult and developing mouse enteric nervous system.
Volume: 32
Issue: 20
Pages: 4483-4492.e5
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Publication
28760865 | J:248927
First Author: Clements R
Year: 2017
Journal: J Neurosci
Title: Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development.
Volume: 37
Issue: 35
Pages: 8559-8574
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Publication
18199763 | J:131380
First Author: Arlotta P
Year: 2008
Journal: J Neurosci
Title: Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum.
Volume: 28
Issue: 3
Pages: 622-32
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Publication
28199486 | J:240687
First Author: Park KU
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Gsg1, Trnp1, and Tmem215 Mark Subpopulations of Bipolar Interneurons in the Mouse Retina.
Volume: 58
Issue: 2
Pages: 1137-1150
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Publication
20463215 | J:160529
First Author: Katoh K
Year: 2010
Journal: J Neurosci
Title: Blimp1 suppresses Chx10 expression in differentiating retinal photoreceptor precursors to ensure proper photoreceptor development.
Volume: 30
Issue: 19
Pages: 6515-26
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Scgn<em1Smoc> | MGI:7292190
Name: secretagogin, EF-hand calcium binding protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7718244 | C57BL/6JSmoc-Scgn<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
10811645 | J:63913
First Author: Wagner L
Year: 2000
Journal: J Biol Chem
Title: Cloning and expression of secretagogin, a novel neuroendocrine- and pancreatic islet of Langerhans-specific Ca2+-binding protein.
Volume: 275
Issue: 32
Pages: 24740-51
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Publication
20020539 | -
First Author: Puthussery T
Year: 2010
Journal: J Comp Neurol
Title: Localization of the calcium-binding protein secretagogin in cone bipolar cells of the mammalian retina.
Volume: 518
Issue: 4
Pages: 513-25
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Publication
21528130 | -
First Author: Bauer MC
Year: 2011
Journal: Mol Biosyst
Title: Identification of a high-affinity network of secretagogin-binding proteins involved in vesicle secretion.
Volume: 7
Issue: 7
Pages: 2196-204
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Publication
21982882 | -
First Author: Alpár A
Year: 2012
Journal: Cell Signal
Title: The renaissance of Ca2+-binding proteins in the nervous system: secretagogin takes center stage.
Volume: 24
Issue: 2
Pages: 378-87
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Publication
19241471 | -
First Author: Bitto E
Year: 2009
Journal: Proteins
Title: X-ray structure of Danio rerio secretagogin: A hexa-EF-hand calcium sensor.
Volume: 76
Issue: 2
Pages: 477-83
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Protein Domain
IPR035798 | EFh_SCGN
Type: Domain
Description: Secretagogin (SCGN) is a six EF-hand calcium-binding protein expressed in neuroendocrine, pancreatic endocrine and retinal cells [, ]. It plays a crucial role in cell apoptosis, receptor signaling and differentiation. It is also involved in vesicle secretion through binding to various proteins, including SNAP25, SNAP23, DOC2alpha, ARFGAP2, rootletin, KIF5B, beta-tubulin, DDAH-2, ATP-synthase and myeloid leukemiafactor 2 []. SCGN functions as a calcium sensor/coincidence detector modulating vesicular exocytosis of neurotransmitters, neuropeptides or hormones. It also serves as a calcium buffer in neurons []. Thus, SCGN may be linked to the pathogenesis of neurological diseases such as Alzheimer's, and also acts as a serum marker of neuronal damage, or as a tumor biomarker.SCGN consists of the three globular domains each of which contains a pair of EF-hand motifs []. All six EF hand motifs of SCGN in some eukaryotes, including D. rerio, X. laevis, M. domestica, G. gallus, O. anatinus, could potentially bind six calcium ions. In contrast, SCGNs from higher eukaryotes have at least one non-functional EF-hand motif due to the mutation(s) or deletions. For instance, the EF1 loop does not coordinate calcium ion due to the key residue asparagine replaced by lysine in SCGNs of many mammalian species. Moreover, the EF2 loop seems to be competent for calcium-binding in most mammalian SCGNs except for human and chimpanzee orthologues [].
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Publication
31734536 | J:311519
 
First Author: Sharma AK
Year: 2019
Journal: iScience
Title: Secretagogin Regulates Insulin Signaling by Direct Insulin Binding.
Volume: 21
Pages: 736-753
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Protein
Q91WD9
Organism: Mus musculus/domesticus
Length: 276  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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