Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3724849 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1738322 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5421501 |
Age: |
embryonic day 14.5 |
Image: |
MH1427; Specimen C1565 |
|
Specimen Label: |
MH1427; Specimen C1565 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724849 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1802422 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5421501 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH1427; Specimen C1565 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691644 |
Age: |
postnatal adult |
Image: |
MRC Harwell_902095 |
|
Specimen Label: |
MRC Harwell_902095 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691644 |
Age: |
postnatal adult |
Image: |
MRC Harwell_902101 |
|
Specimen Label: |
MRC Harwell_902101 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691644 |
Age: |
postnatal adult |
Image: |
MRC Harwell_902105 |
|
Specimen Label: |
MRC Harwell_902105 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724849 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1768022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5421501 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was not detected in the skull (base and vault). |
Specimen Label: |
MH1427; Specimen C1565 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724849 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:2672022 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5421501 |
Age: |
embryonic day 14.5 |
Image: |
MH1427; Specimen C1565 |
Note: |
Expression was weak in whisker follicle. |
Specimen Label: |
MH1427; Specimen C1565 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jones KS |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Neonatal NMDA receptor blockade disrupts spike timing and glutamatergic synapses in fast spiking interneurons in a NMDA receptor hypofunction model of schizophrenia. |
Volume: |
9 |
Issue: |
10 |
Pages: |
e109303 |
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•
•
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Publication |
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2022 |
Journal: |
JCI Insight |
Title: |
Succinate dehydrogenase inversely regulates red cell distribution width and healthy life span in chronically hypoxic mice. |
Volume: |
7 |
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17 |
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•
•
•
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Publication |
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Journal: |
J Biol Chem |
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Publication |
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2021 |
Journal: |
Biochim Biophys Acta Gen Subj |
Title: |
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1865 |
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3 |
Pages: |
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Publication |
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Journal: |
Cell Metab |
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Publication |
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Journal: |
Biochim Biophys Acta |
Title: |
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2 |
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Publication |
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Publication |
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Year: |
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Volume: |
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Publication |
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Genome Res |
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Post-entrapment genome engineering: first exon size does not affect the expression of fusion transcripts generated by gene entrapment. |
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428-35 |
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Publication |
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Title: |
Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin. |
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Publication |
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Journal: |
Essays Biochem |
Title: |
Assembly of mammalian oxidative phosphorylation complexes I-V and supercomplexes. |
Volume: |
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Issue: |
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Pages: |
255-270 |
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•
•
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Publication |
First Author: |
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Year: |
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Journal: |
BMC Genomics |
Title: |
An analysis of expression patterns of genes encoding proteins with catalytic activities. |
Volume: |
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Pages: |
232 |
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Publication |
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Mol Cell Biol |
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737-50 |
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Publication |
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Title: |
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Database Release |
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UniProt-GOA |
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Title: |
Gene Ontology annotation based on UniPathway vocabulary mapping |
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PLoS Biol |
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MGI download of modified allele data from IKMC and creation of new knockout alleles |
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Characterization of the human SDHC gene encoding of the integral membrane proteins of succinate-quinone oxidoreductase in mitochondria. |
Volume: |
213 |
Issue: |
1-2 |
Pages: |
133-40 |
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•
•
•
•
•
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UniProt Feature |
Begin: |
102 |
Description: |
Iron (heme b axial ligand); shared with SDHC |
Type: |
metal ion-binding site |
End: |
102 |
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•
•
•
•
•
|
Publication |
First Author: |
Burger G |
Year: |
1996 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Genes encoding the same three subunits of respiratory complex II are present in the mitochondrial DNA of two phylogenetically distant eukaryotes. |
Volume: |
93 |
Issue: |
6 |
Pages: |
2328-32 |
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•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
In Escherichia coli and many other bacteria, two small, hydrophobic, mutually homologous subunits of succinate dehydrogenase (a TCA cycle enzyme) are SdhC and SdhD []. This entry is the SdhD, the hydrophobic membrane anchor protein. SdhC is apocytochrome b558, which also plays a role in anchoring the complex. |
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•
•
•
•
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Publication |
First Author: |
Hartman T |
Year: |
2014 |
Journal: |
PLoS Pathog |
Title: |
Succinate dehydrogenase is the regulator of respiration in Mycobacterium tuberculosis. |
Volume: |
10 |
Issue: |
11 |
Pages: |
e1004510 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
In Escherichia coli and many other bacteria, two small, hydrophobic, mutually homologous subunits of succinate dehydrogenase (a TCA cycle enzyme) are SdhC and SdhD. Both SdhC and SdhD participate in anchoring the complex. This entry represents SdhC, the cytochrome b subunit, also called b556 in bacteria.Mycobacterium contains two operons which are predicted to encode succinate dehydrogenase enzymes (Sdh-1 and Sdh-2). SdhC is encoded in the operon sdhCDAB for Sdh-2. Sdh1 (and not Sdh2) seems to be the primary aerobic succinate dehydrogenase of M. tuberculosis []. |
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•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
In Escherichia coli and many other bacteria, two small, hydrophobic, mutually homologous subunits of succinate dehydrogenase (a TCA cycle enzyme) are SdhC and SdhD. This entry represents SdhC, the cytochrome b subunit, called b556 in bacteria and b560 in mitochondria. SdhD (see ) is called the hydrophobic membrane anchor subunit, although both SdhC and SdhD participate in anchoring the complex. In some bacteria, this cytochrome b subunit is replaced my a member of the cytochrome b558 family (see ). |
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Publication |
First Author: |
Dong Q |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia. |
Volume: |
13 |
Issue: |
1 |
Pages: |
6107 |
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•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
169
 |
Fragment?: |
false |
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•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
135
 |
Fragment?: |
false |
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•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
169
 |
Fragment?: |
false |
|
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•
•
•
•
|
Publication |
First Author: |
Paddenberg R |
Year: |
2012 |
Journal: |
Cardiovasc Res |
Title: |
Mitochondrial complex II is essential for hypoxia-induced pulmonary vasoconstriction of intra- but not of pre-acinar arteries. |
Volume: |
93 |
Issue: |
4 |
Pages: |
702-10 |
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•
•
•
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