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Search results 201 to 277 out of 277 for Sdhd

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Type Details Score
Publication
26522426 | J:227906
 
First Author: Lussey-Lepoutre C
Year: 2015
Journal: Nat Commun
Title: Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism.
Volume: 6
Pages: 8784
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Publication
24439383 | J:205562
First Author: Platero-Luengo A
Year: 2014
Journal: Cell
Title: An O2-sensitive glomus cell-stem cell synapse induces carotid body growth in chronic hypoxia.
Volume: 156
Issue: 1-2
Pages: 291-303
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Publication
35486677 | J:333884
First Author: Chen X
Year: 2022
Journal: Sci Immunol
Title: Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation.
Volume: 7
Issue: 70
Pages: eabm8161
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Publication
3003061 | J:320283
First Author: Corbin JD
Year: 1986
Journal: J Biol Chem
Title: Studies of cGMP analog specificity and function of the two intrasubunit binding sites of cGMP-dependent protein kinase.
Volume: 261
Issue: 3
Pages: 1208-14
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Publication
19808025 | J:153657
First Author: Forner F
Year: 2009
Journal: Cell Metab
Title: Proteome differences between brown and white fat mitochondria reveal specialized metabolic functions.
Volume: 10
Issue: 4
Pages: 324-35
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Publication
16120479 | J:109661
First Author: Schilling B
Year: 2006
Journal: Biochim Biophys Acta
Title: Proteomic analysis of succinate dehydrogenase and ubiquinol-cytochrome c reductase (Complex II and III) isolated by immunoprecipitation from bovine and mouse heart mitochondria.
Volume: 1762
Issue: 2
Pages: 213-22
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Publication
26123588 | J:236514
 
First Author: Lepoutre-Lussey C
Year: 2016
Journal: Mol Cell Endocrinol
Title: From Nf1 to Sdhb knockout: Successes and failures in the quest for animal models of pheochromocytoma.
Volume: 421
Pages: 40-8
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Publication
28204537 | J:242046
First Author: Sharma S
Year: 2017
Journal: Hum Mol Genet
Title: Mitochondrial complex II regulates a distinct oxygen sensing mechanism in monocytes.
Volume: 26
Issue: 7
Pages: 1328-1339
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Publication
28619824 | J:242895
First Author: Brici D
Year: 2017
Journal: Development
Title: Setd1b, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression program.
Volume: 144
Issue: 14
Pages: 2606-2617
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Publication
15939374 | J:98707
First Author: Ferguson DA
Year: 2005
Journal: Gene Expr Patterns
Title: eXPRESSION: an in silico tool to predict patterns of gene expression.
Volume: 5
Issue: 5
Pages: 619-28
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Publication
38418556 | J:346910
First Author: Ayyangar U
Year: 2024
Journal: EMBO J
Title: Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin.
Volume: 43
Issue: 7
Pages: 1113-1134
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Publication
30030361 | J:320063
First Author: Signes A
Year: 2018
Journal: Essays Biochem
Title: Assembly of mammalian oxidative phosphorylation complexes I-V and supercomplexes.
Volume: 62
Issue: 3
Pages: 255-270
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Publication
15031102 | J:92177
First Author: Powles N
Year: 2004
Journal: Dev Biol
Title: Identification and analysis of genes from the mouse otic vesicle and their association with developmental subprocesses through in situ hybridization.
Volume: 268
Issue: 1
Pages: 24-38
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Publication
14595844 | J:86589
First Author: McClive PJ
Year: 2003
Journal: Genesis
Title: Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad.
Volume: 37
Issue: 2
Pages: 84-90
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Publication
17626619 | J:125993
 
First Author: Cankaya M
Year: 2007
Journal: BMC Genomics
Title: An analysis of expression patterns of genes encoding proteins with catalytic activities.
Volume: 8
Pages: 232
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Publication
27215380 | J:236179
First Author: Bowman CE
Year: 2016
Journal: Mol Cell Biol
Title: Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Volume: 36
Issue: 15
Pages: 2089-104
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Publication
14651853 | J:86816
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
15883710 | -
First Author: Pawlu C
Year: 2005
Journal: Fam Cancer
Title: Mutations of the SDHB and SDHD genes.
Volume: 4
Issue: 1
Pages: 49-54
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UniProt Feature
UniProt Feature
Begin: 127
Description: Iron (heme b axial ligand); shared with SDHD
Type: metal ion-binding site
End: 127
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Gene
644096 | SDHAF1
Type: gene
Organism: human
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Protein Domain
IPR014314 | Succ_DH_cytb556
Type: Family
Description: In Escherichia coli and many other bacteria, two small, hydrophobic, mutually homologous subunits of succinate dehydrogenase (a TCA cycle enzyme) are SdhC and SdhD. This entry represents SdhC, the cytochrome b subunit, called b556 in bacteria and b560 in mitochondria. SdhD (see ) is called the hydrophobic membrane anchor subunit, although both SdhC and SdhD participate in anchoring the complex. In some bacteria, this cytochrome b subunit is replaced my a member of the cytochrome b558 family (see ).
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Gene
6390 | SDHB
Type: gene
Organism: human
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Gene
6389 | SDHA
Type: gene
Organism: human
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DO Term
DOID:0060537 | mitochondrial complex II deficiency
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Publication
8637872 | -
First Author: Burger G
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Genes encoding the same three subunits of respiratory complex II are present in the mitochondrial DNA of two phylogenetically distant eukaryotes.
Volume: 93
Issue: 6
Pages: 2328-32
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Protein Domain
IPR014312 | Succ_DH_anchor
Type: Family
Description: In Escherichia coli and many other bacteria, two small, hydrophobic, mutually homologous subunits of succinate dehydrogenase (a TCA cycle enzyme) are SdhC and SdhD []. This entry is the SdhD, the hydrophobic membrane anchor protein. SdhC is apocytochrome b558, which also plays a role in anchoring the complex.
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Publication
25412183 | -
First Author: Hartman T
Year: 2014
Journal: PLoS Pathog
Title: Succinate dehydrogenase is the regulator of respiration in Mycobacterium tuberculosis.
Volume: 10
Issue: 11
Pages: e1004510
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Protein Domain
IPR039023 | SdhC_prok
Type: Family
Description: In Escherichia coli and many other bacteria, two small, hydrophobic, mutually homologous subunits of succinate dehydrogenase (a TCA cycle enzyme) are SdhC and SdhD. Both SdhC and SdhD participate in anchoring the complex. This entry represents SdhC, the cytochrome b subunit, also called b556 in bacteria.Mycobacterium contains two operons which are predicted to encode succinate dehydrogenase enzymes (Sdh-1 and Sdh-2). SdhC is encoded in the operon sdhCDAB for Sdh-2. Sdh1 (and not Sdh2) seems to be the primary aerobic succinate dehydrogenase of M. tuberculosis [].
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Publication
39357516 | J:358146
     
First Author: Han G
Year: 2024
Journal: Cell Stem Cell
Title: Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance.
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Publication
15989954 | -
First Author: Sun F
Year: 2005
Journal: Cell
Title: Crystal structure of mitochondrial respiratory membrane protein complex II.
Volume: 121
Issue: 7
Pages: 1043-57
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Publication
10648604 | -
First Author: Koehler CM
Year: 2000
Journal: Mol Cell Biol
Title: Tim18p, a new subunit of the TIM22 complex that mediates insertion of imported proteins into the yeast mitochondrial inner membrane.
Volume: 20
Issue: 4
Pages: 1187-93
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Publication
10637294 | -
First Author: Kerscher O
Year: 2000
Journal: Mol Biol Cell
Title: Tim18p is a new component of the Tim54p-Tim22p translocon in the mitochondrial inner membrane.
Volume: 11
Issue: 1
Pages: 103-16
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Publication
14504216 | -
First Author: Dunn CD
Year: 2003
Journal: Genetics
Title: Suppression of a defect in mitochondrial protein import identifies cytosolic proteins required for viability of yeast cells lacking mitochondrial DNA.
Volume: 165
Issue: 1
Pages: 35-45
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Publication
16288654 | -
 
First Author: Bayley JP
Year: 2005
Journal: BMC Med Genet
Title: The SDH mutation database: an online resource for succinate dehydrogenase sequence variants involved in pheochromocytoma, paraganglioma and mitochondrial complex II deficiency.
Volume: 6
Pages: 39
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Publication
12844553 | -
First Author: Kristal BS
Year: 2003
Journal: Sci Aging Knowledge Environ
Title: Structure-(Dys)function relationships in mitochondrial electron transport chain complex II?
Volume: 2003
Issue: 5
Pages: PE3
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Publication
16143825 | -
First Author: Brière JJ
Year: 2005
Journal: Cell Mol Life Sci
Title: Succinate dehydrogenase deficiency in human.
Volume: 62
Issue: 19-20
Pages: 2317-24
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Protein Domain
IPR007992 | CybS
Type: Family
Description: This family consists of mitochondrial succinate dehydrogenase [ubiquinone]cytochrome b small subunit CybS (also known an SQR) and import inner membrane translocase subunit Tim18. Members of this subfamily are classified as Type C SQRs because they contain two transmembrane subunits and one heme group. CybS and CybL are the two transmembrane proteins of eukaryotic SQRs. They contain heme and quinone binding sites. CybS is the eukaryotic homologue of the bacterial SdhD subunit.CybS is a membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) []. CybS is composed of a flavoprotein catalytic subunit, an iron-sulfur protein and one or two hydrophobic transmembrane subunits []. The two-electron oxidation of succinate in the flavoprotein active site is coupled to the two-electron reduction of quinone in the transmembrane subunits via electron transport through FAD and three iron-sulfur centres []. The reversible reduction of quinone is an essential feature of respiration, allowing transfer of electrons between respiratory complexes. Mutations in human Complex II result in various physiological disorders including hereditary paraganglioma and pheochromocytoma tumors. The gene encoding for the SdhD subunit is classified as a tumor suppressor gene [, , ].In Saccharomyces cerevisiae, Tim18 is a component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force. Its role in the complex is unclear but it may be involved in the assembly and stabilisation of the TIM22 complex [, , ].
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Publication
25695889 | J:317001
First Author: Xekouki P
Year: 2015
Journal: J Clin Endocrinol Metab
Title: Pituitary adenoma with paraganglioma/pheochromocytoma (3PAs) and succinate dehydrogenase defects in humans and mice.
Volume: 100
Issue: 5
Pages: E710-9
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Protein
Q9CXV1
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: false
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Protein
Q9CZB0
Organism: Mus musculus/domesticus
Length: 169  
Fragment?: false
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Protein
Q9D6J9
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: false
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Protein
F8WGB3
Organism: Mus musculus/domesticus
Length: 135  
Fragment?: false
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Protein
Q5XK33
Organism: Mus musculus/domesticus
Length: 169  
Fragment?: false
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