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Search results 201 to 300 out of 573 for Sds

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Type Details Score
Protein Domain
IPR038536 | Alkyl/aryl-sulf_dimr_sf
Type: Homologous_superfamily
Description: This α-helical dimerisation domain is found in alkyl/aryl-sulfatases such as the Saccharomyces cerevisiae BDS1 (). BDS1 enables the use of SDS and 4-nitrocatechol as sulfur source [].
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Protein Domain
IPR029228 | Alkyl_sulf_dimr
Type: Domain
Description: Thisdomain is found in alkyl sulfatases such as the Pseudomonas aeruginosa SDS hydrolase SdsA1 (), where it acts as a dimerisation domain [].
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Protein Domain
IPR023740 | Spermidine_export_MdtJ
Type: Family
Description: Spermidine export protein MdtJ catalyzes the excretion of spermidine. It can also confer resistance to deoxycholate and SDS [, ]. It is induced by spermidine.
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Protein Domain
IPR023737 | Spermidine_export_MdtI
Type: Family
Description: Spermidine export protein MdtI catalyzes the excretion of spermidine. It can also confer resistance to deoxycholate and SDS [, ]. It is integral to membrane [].
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Publication
18039771 | -
First Author: Higashi K
Year: 2008
Journal: J Bacteriol
Title: Identification of a spermidine excretion protein complex (MdtJI) in Escherichia coli.
Volume: 190
Issue: 3
Pages: 872-8
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Publication
23061549 | -
First Author: Knaus T
Year: 2012
Journal: FEBS J
Title: Structure and mechanism of an inverting alkylsulfatase from Pseudomonas sp. DSM6611 specific for secondary alkyl sulfates.
Volume: 279
Issue: 23
Pages: 4374-84
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Publication
31907968 | -
First Author: Kida Y
Year: 2020
Journal: Microbiol Immunol
Title: SdsA1, a secreted sulfatase, contributes to the in vivo virulence of Pseudomonas aeruginosa in mice.
Volume: 64
Issue: 4
Pages: 280-295
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Publication
25066955 | -
First Author: Liang Y
Year: 2014
Journal: Protein Sci
Title: Structural and functional analysis show that the Escherichia coli uncharacterized protein YjcS is likely an alkylsulfatase.
Volume: 23
Issue: 10
Pages: 1442-50
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Protein Domain
IPR044097 | Bds1/SdsA1_MBL-fold
Type: Domain
Description: This entry represents a group of arylsulfatases, including Bds1 from budding yeasts, SdsA1 from Pseudomonas aeruginosa and YjcS from E. coli. SdsA1 is a secreted SDS hydrolase that allows the bacterium to use primary sulfates such as the detergent SDS common in commercial personal hygiene products as a sole carbon or sulfur source [, ]. SdsA1 also contributes to the in vivo virulence of P. aeruginosa by playing a central role in the degradation of mucin []. YjcS is also able to cleave SDS []. Bds1, also known as bacterially-derived sulfatase, is required for use of alkyl- and aryl-sulfates as sulfur sources [].
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Strain
MGI:2162979 | BXD32/TyJ
Attribute String: recombinant inbred (RI)
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Strain
MGI:2160892 | C3.SW-H2<b>/SnJ
Attribute String: congenic, mutant strain, major histocompatibility congenic
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Allele
Psen1<tm1Pcw> | MGI:1930934
Name: presenilin 1; targeted mutation 1, Philip C Wong
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:2163011 | D1.LP-H2<b> H2-T18<b?>/SnJ
Attribute String: congenic, mutant strain, major histocompatibility congenic
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Strain
MGI:3051844 | BXD24/TyJ
Attribute String: recombinant inbred (RI)
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Strain
MGI:6357686 | B10Sn.LP-Zfp106<H3a-b> B2m<a>/DcrMmjax
Attribute String: variant allele, mutant strain, congenic
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Strain
MGI:6357685 | B10Sn.LP-Zfp106<H3a-b> B2m<a> H3b<b>/DcrMmjax
Attribute String: congenic, mutant strain, variant allele
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Strain
MGI:2162539 | BXD12/TyJ
Attribute String: recombinant inbred (RI)
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Strain
MGI:2162396 | BXD23/TyJ
Attribute String: recombinant inbred (RI)
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Strain
MGI:2163572 | BXD15/TyJ
Attribute String: recombinant inbred (RI)
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Strain
MGI:6117222 | BXD29/TyJ
Attribute String: Not specified
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Strain
MGI:2162368 | BXD20/TyJ
Attribute String: recombinant inbred (RI)
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Strain
MGI:2161806 | B10.C-H3<c> H13<?> A/(28NX)SnJ
Attribute String: congenic, mutant strain, minor histocompatibility congenic
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Allele
B2m<b> | MGI:6711994
 
Name: beta-2 microglobulin; b variant
Allele Type: Spontaneous
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Publication
16684886 | -
First Author: Hagelueken G
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases.
Volume: 103
Issue: 20
Pages: 7631-6
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Publication
15947202 | -
First Author: Hall C
Year: 2005
Journal: Eukaryot Cell
Title: Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae.
Volume: 4
Issue: 6
Pages: 1102-15
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Publication
15163631 | J:91057
First Author: Louvi A
Year: 2004
Journal: Development
Title: Presenilin 1 in migration and morphogenesis in the central nervous system.
Volume: 131
Issue: 13
Pages: 3093-105
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Publication
11814648 | J:107974
First Author: Morton RA
Year: 2002
Journal: Neurosci Lett
Title: Impairment in hippocampal long-term potentiation in mice under-expressing the Alzheimer's disease related gene presenilin-1.
Volume: 319
Issue: 1
Pages: 37-40
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Publication
15123735 | J:90565
First Author: Wilson CA
Year: 2004
Journal: J Cell Biol
Title: Degradative organelles containing mislocalized alpha-and beta-synuclein proliferate in presenilin-1 null neurons.
Volume: 165
Issue: 3
Pages: 335-46
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Publication
15972961 | J:99508
First Author: Chevallier NL
Year: 2005
Journal: Am J Pathol
Title: Perturbed neurogenesis in the adult hippocampus associated with presenilin-1 A246E mutation.
Volume: 167
Issue: 1
Pages: 151-9
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Publication
35486730 | J:338551
First Author: Lie PPY
Year: 2022
Journal: Sci Adv
Title: Axonal transport of late endosomes and amphisomes is selectively modulated by local Ca(2+) efflux and disrupted by PSEN1 loss of function.
Volume: 8
Issue: 17
Pages: eabj5716
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Publication
15703408 | J:98238
First Author: Parent AT
Year: 2005
Journal: J Neurosci
Title: Presenilin attenuates receptor-mediated signaling and synaptic function.
Volume: 25
Issue: 6
Pages: 1540-9
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Publication
9856475 | J:111807
First Author: Naruse S
Year: 1998
Journal: Neuron
Title: Effects of PS1 deficiency on membrane protein trafficking in neurons.
Volume: 21
Issue: 5
Pages: 1213-21
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Strain
MGI:2160345 | DBA/2-B2m<b>
Attribute String: mutant strain
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Strain
MGI:5649597 | (C57BL/6 x BALB/c)F1-B2m<b>
Attribute String: F1 hybrid, mutant stock
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Genotype
Genotype
Symbol: Psen1/Psen1
Background: involves: 129S7/SvEvBrd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Psen1/Psen1<+>
Background: involves: 129S7/SvEvBrd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Psen1/Psen1
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:2162200 | BXD18/TyJ
Attribute String: recombinant inbred (RI)
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Strain
MGI:2163875 | BXD19/TyJ
Attribute String: recombinant inbred (RI)
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Strain
MGI:2163892 | BXD21/TyJ
Attribute String: recombinant inbred (RI)
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Strain
MGI:2384208 | BXD16/TyJ
Attribute String: recombinant inbred (RI)
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Strain
MGI:2165478 | NOD.Cg Prkdc<scid>-B2m<b>/Dvs
Attribute String: congenic, mutant strain
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Publication
17359917 | J:132095
First Author: Peng CY
Year: 2007
Journal: Neuron
Title: Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord.
Volume: 53
Issue: 6
Pages: 813-27
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HT Experiment
E-GEOD-17324 | Sex-dependent gene regulatory networks of the heart rhythm
Series Id: GSE17324
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Publication
8187880 | J:113692
First Author: Loeber G
Year: 1994
Journal: FEBS Lett
Title: Characterization of cytosolic malic enzyme in human tumor cells.
Volume: 344
Issue: 2-3
Pages: 181-6
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Publication
6165997 | J:6520
First Author: Gates FT 3rd
Year: 1981
Journal: Proc Natl Acad Sci U S A
Title: Complete amino acid sequence of murine beta 2-microglobulin: structural evidence for strain-related polymorphism.
Volume: 78
Issue: 1
Pages: 554-8
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Strain
MGI:2163277 | BXD8/TyJ
Attribute String: recombinant inbred (RI)
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Strain
MGI:2161567 | A.BY-H2<bc> H2-T18<f>/SnJ
Attribute String: congenic, mutant strain, major histocompatibility congenic
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Publication
9153393 | J:40308
First Author: Wong PC
Year: 1997
Journal: Nature
Title: Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm.
Volume: 387
Issue: 6630
Pages: 288-92
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Publication
10557208 | J:58465
First Author: Donoviel DB
Year: 1999
Journal: Genes Dev
Title: Mice lacking both presenilin genes exhibit early embryonic patterning defects.
Volume: 13
Issue: 21
Pages: 2801-10
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Publication
15122901 | J:115485
First Author: Qyang Y
Year: 2004
Journal: Biochemistry
Title: Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage.
Volume: 43
Issue: 18
Pages: 5352-9
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Publication
18539391 | J:138403
First Author: Gu F
Year: 2008
Journal: Neurosci Lett
Title: Enhanced oxidative stress is an early event during development of Alzheimer-like pathologies in presenilin conditional knock-out mice.
Volume: 440
Issue: 1
Pages: 44-8
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Publication
12684521 | J:84109
First Author: Lai MT
Year: 2003
Journal: J Biol Chem
Title: Presenilin-1 and presenilin-2 exhibit distinct yet overlapping gamma-secretase activities.
Volume: 278
Issue: 25
Pages: 22475-81
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Publication
18822370 | J:143331
First Author: Zhu M
Year: 2008
Journal: Free Radic Biol Med
Title: Increased oxidative stress and astrogliosis responses in conditional double-knockout mice of Alzheimer-like presenilin-1 and presenilin-2.
Volume: 45
Issue: 10
Pages: 1493-9
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Publication
17222949 | J:137701
First Author: Zhang H
Year: 2008
Journal: Neurobiol Aging
Title: Presenilins regulate the cellular level of the tumor suppressor PTEN.
Volume: 29
Issue: 5
Pages: 653-60
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Publication
21910732 | J:178371
First Author: Kim J
Year: 2011
Journal: J Neurochem
Title: Characterization of nectin processing mediated by presenilin-dependent γ-secretase.
Volume: 119
Issue: 5
Pages: 945-56
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Publication
12717232 | J:267087
First Author: Haskova Z
Year: 2003
Journal: Transplantation
Title: An immunodominant minor histocompatibility alloantigen that initiates corneal allograft rejection.
Volume: 75
Issue: 8
Pages: 1368-74
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Publication
6187676 | J:7014
First Author: Michaelson J
Year: 1983
Journal: Immunogenetics
Title: Genetics of beta-2 microglobulin in the mouse.
Volume: 17
Issue: 3
Pages: 219-60
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Genotype
Genotype
Symbol: Psen1/Psen1 Psen2/Psen2<+>
Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Psen1/Psen1<+> Psen2/Psen2<+>
Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Psen1/Psen1<+> Psen2/Psen2
Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Psen1/Psen1 Psen2/Psen2
Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Protein Domain
IPR042079 | ATP_synt_F1_beta_sf
Type: Homologous_superfamily
Description: This superfamily includes the F1 beta subunit of ATP synthase.F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c.The NMR solution structure of the protein in SDS micelles was found to contain two helices, an N-terminal amphipathic α-helix and a C-terminal α-helix separated by a large unstructured internal domain. The N-terminal α-helix is the Tom20 receptor binding site whereas the C-terminal α-helix is located upstream of the mitochondrial processing peptidase cleavage site [].
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Protein Domain
IPR020971 | ATP_synth_F1_beta_su
Type: Domain
Description: F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c. This entry represents the beta subunit of the F1 component.The NMR solution structure of the protein in SDS micelles was found to contain two helices, an N-terminal amphipathic α-helix and a C-terminal α-helix separated by a large unstructured internal domain. The N-terminal α-helix is the Tom20 receptor binding site whereas the C-terminal α-helix is located upstream of the mitochondrial processing peptidase cleavage site [].
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Protein Domain
IPR021187 | Band_41_protein_chordates
Type: Family
Description: Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating physical properties of the membrane, such as mechanical stability and de-formability, by stabilising spectrin-actin interactions [, , ]. It is required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase [].The protein has been shown to associate with the nuclear mitotic apparatus, the contractile apparatus and tight junctions. Defects in this protein can cause elliptocytosis type 1 and hereditary pyropoikilocytosis.Note: Band 4.1 and Band 7 () proteins refer to human erythrocyte membrane proteins separated by SDS polyacrylamide gels and stained with coomassie blue [].
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Protein Domain
IPR021566 | Doppel
Type: Family
Description: Dpl is a homologue related to the prion protein (PrP). Dpl is toxic to neurons and is expressed in the brains of mice that do not express PrP. In DHPC and SDS micelles, Dpl shoes about 40% α-helical structure however in aqueous solution it consists of a random coil. The alpha helical segment can adopt a transmembrane localisation also in a membrane. The unprocessed Dpl protein is thought to posses a possible channel formation mechanism which may be related to toxicity through direct interaction with cell membranes and damage to the cell membrane.
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Publication
11566977 | -
First Author: Nishino K
Year: 2001
Journal: J Bacteriol
Title: Analysis of a complete library of putative drug transporter genes in Escherichia coli.
Volume: 183
Issue: 20
Pages: 5803-12
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Publication
15037074 | -
First Author: Moberg P
Year: 2004
Journal: J Mol Biol
Title: NMR solution structure of the mitochondrial F1beta presequence from Nicotiana plumbaginifolia.
Volume: 336
Issue: 5
Pages: 1129-40
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Publication
11017195 | -
First Author: Han BG
Year: 2000
Journal: Nat Struct Biol
Title: Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization.
Volume: 7
Issue: 10
Pages: 871-5
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Publication
1647028 | -
First Author: Subrahmanyam G
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation of protein 4.1 on tyrosine-418 modulates its function in vitro.
Volume: 88
Issue: 12
Pages: 5222-6
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Publication
23870127 | -
First Author: Kiyomitsu T
Year: 2013
Journal: Cell
Title: Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase.
Volume: 154
Issue: 2
Pages: 391-402
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Publication
10350628 | J:55426
First Author: Morris NJ
Year: 1999
Journal: Biochim Biophys Acta
Title: Cloning and preliminary characterization of a 121 kDa protein with multiple predicted C2 domains.
Volume: 1431
Issue: 2
Pages: 525-30
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Publication
16971387 | J:117255
First Author: Liu Y
Year: 2006
Journal: J Biol Chem
Title: Dimerization of Laforin is required for its optimal phosphatase activity, regulation of GSK3beta phosphorylation, and Wnt signaling.
Volume: 281
Issue: 46
Pages: 34768-74
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Publication
9518179 | J:45610
First Author: Kaplan B
Year: 1997
Journal: J Chromatogr B Biomed Sci Appl
Title: Isolation and purification of two major serum amyloid A isotypes SAA1 and SAA2 from the acute phase plasma of mice.
Volume: 704
Issue: 1-2
Pages: 69-76
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Publication
32726631 | J:323524
First Author: Holderith N
Year: 2020
Journal: Cell Rep
Title: A High-Resolution Method for Quantitative Molecular Analysis of Functionally Characterized Individual Synapses.
Volume: 32
Issue: 4
Pages: 107968
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Publication
11290790 | J:113714
First Author: Bikoff EK
Year: 2001
Journal: J Immunol
Title: Relaxed DM requirements during class II peptide loading and CD4+ T cell maturation in BALB/c mice.
Volume: 166
Issue: 8
Pages: 5087-98
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Publication
9723702 | J:136433
First Author: Barton GM
Year: 1998
Journal: Int Immunol
Title: An altered invariant chain protein with an antigenic peptide in place of CLIP forms SDS-stable complexes with class II alphabeta dimers and facilitates highly efficient peptide loading.
Volume: 10
Issue: 8
Pages: 1159-65
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Publication
27666011 | J:239112
First Author: Zambetti NA
Year: 2016
Journal: Cell Stem Cell
Title: Mesenchymal Inflammation Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Disease Evolution in Human Pre-leukemia.
Volume: 19
Issue: 5
Pages: 613-627
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Publication
7969452 | J:21373
First Author: Tamemoto H
Year: 1994
Journal: Nature
Title: Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.
Volume: 372
Issue: 6502
Pages: 182-6
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Publication
34826234 | J:321992
First Author: Hoshi Y
Year: 2021
Journal: Sci Adv
Title: Thermosensitive receptors in neural stem cells link stress-induced hyperthermia to impaired neurogenesis via microglial engulfment.
Volume: 7
Issue: 48
Pages: eabj8080
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Publication
33850125 | J:333602
First Author: Tamim I
Year: 2021
Journal: Nat Commun
Title: Spreading depression as an innate antiseizure mechanism.
Volume: 12
Issue: 1
Pages: 2206
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Publication
31151987 | J:280074
First Author: Tan S
Year: 2019
Journal: Blood
Title: EFL1 mutations impair eIF6 release to cause Shwachman-Diamond syndrome.
Volume: 134
Issue: 3
Pages: 277-290
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Publication
6352806 | J:7192
First Author: Farrar JJ
Year: 1983
Journal: J Immunol
Title: Biochemical and physicochemical characterization of mouse B cell growth factor: a lymphokine distinct from interleukin 2.
Volume: 131
Issue: 4
Pages: 1838-42
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Publication
10193409 | J:53533
First Author: Fernando GJ
Year: 1999
Journal: Clin Exp Immunol
Title: Expression, purification and immunological characterization of the transforming protein E7, from cervical cancer-associated human papillomavirus type 16.
Volume: 115
Issue: 3
Pages: 397-403
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Strain
MGI:2161533 | B10.UW-H3<b> Tgm3<we> Pax1<un> a<t>/SnJ
Attribute String: mutant strain, minor histocompatibility congenic
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Strain
MGI:2159873 | C3HeB/FeJ
Attribute String: inbred strain
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Publication
11937492 | J:75878
First Author: Hitoshi S
Year: 2002
Journal: Genes Dev
Title: Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells.
Volume: 16
Issue: 7
Pages: 846-58
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Publication
31042463 | J:284880
First Author: Deyts C
Year: 2019
Journal: Cell Rep
Title: APP-Mediated Signaling Prevents Memory Decline in Alzheimer's Disease Mouse Model.
Volume: 27
Issue: 5
Pages: 1345-1355.e6
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Publication
9539133 | J:77306
First Author: Qian S
Year: 1998
Journal: Neuron
Title: Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression.
Volume: 20
Issue: 3
Pages: 611-7
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Publication
17556541 | J:122380
First Author: Zhang YW
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression.
Volume: 104
Issue: 25
Pages: 10613-8
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Publication
23563578 | J:197603
First Author: Dolev I
Year: 2013
Journal: Nat Neurosci
Title: Spike bursts increase amyloid-β 40/42 ratio by inducing a presenilin-1 conformational change.
Volume: 16
Issue: 5
Pages: 587-95
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Publication
9539132 | J:182724
First Author: Davis JA
Year: 1998
Journal: Neuron
Title: An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos.
Volume: 20
Issue: 3
Pages: 603-9
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Publication
31221985 | J:279897
First Author: Kastanenka KV
Year: 2019
Journal: Sci Rep
Title: Frequency-dependent exacerbation of Alzheimer's disease neuropathophysiology.
Volume: 9
Issue: 1
Pages: 8964
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Publication
16103124 | J:128865
First Author: Hass MR
Year: 2005
Journal: J Biol Chem
Title: A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein.
Volume: 280
Issue: 44
Pages: 36895-904
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Publication
15207348 | J:91277
First Author: Wang R
Year: 2004
Journal: Neuroscience
Title: Presenilin 1 familial Alzheimer's disease mutation leads to defective associative learning and impaired adult neurogenesis.
Volume: 126
Issue: 2
Pages: 305-12
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Genotype
Genotype
Symbol: Psen1/Psen1
Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Protein
Q9EPM7
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: true
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Protein
A0A1W2P8C0
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: true
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Protein
Q9EPM8
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: true
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Publication
4326772 | -
First Author: Fairbanks G
Year: 1971
Journal: Biochemistry
Title: Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane.
Volume: 10
Issue: 13
Pages: 2606-17
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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