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Search results 201 to 300 out of 331 for Shc3

0.032s
Type Details Score
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_22
Specimen Label: euxassay_009466_22
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_23
Specimen Label: euxassay_009466_23
Detected: true
Specimen Num: 21
GXD Expression  
Probe: MGI:4944267
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4946258
Age: embryonic day 16.5
Image: 3 E16.5
Specimen Label: 3 E16.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4944267
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4946258
Age: embryonic day 16.5
Image: 3 Gut
Specimen Label: 3 Gut
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4944267
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1800824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:4946258
Age: embryonic day 16.5
Image: 3 E16.5
Note: Expression was detected in the hypertrophic chondrocytes and chondrocyte-like cells contained within the nucleus pulposus in the central region of the intervertebral discs.
Specimen Label: 3 E16.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4944267
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1800824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:4946258
Age: embryonic day 16.5
Image: 3 Bone
Note: Expression was detected in the hypertrophic chondrocytes and chondrocyte-like cells contained within the nucleus pulposus in the central region of the intervertebral discs.
Specimen Label: 3 Bone
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_07
Specimen Label: euxassay_009466_07
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_08
Specimen Label: euxassay_009466_08
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_09
Specimen Label: euxassay_009466_09
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_10
Specimen Label: euxassay_009466_10
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_11
Specimen Label: euxassay_009466_11
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_12
Specimen Label: euxassay_009466_12
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_13
Specimen Label: euxassay_009466_13
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_14
Specimen Label: euxassay_009466_14
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_15
Specimen Label: euxassay_009466_15
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_16
Specimen Label: euxassay_009466_16
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_11
Specimen Label: euxassay_009466_11
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_12
Specimen Label: euxassay_009466_12
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_13
Specimen Label: euxassay_009466_13
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_14
Specimen Label: euxassay_009466_14
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_15
Specimen Label: euxassay_009466_15
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_11
Specimen Label: euxassay_009466_11
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_12
Specimen Label: euxassay_009466_12
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_13
Specimen Label: euxassay_009466_13
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_14
Specimen Label: euxassay_009466_14
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_15
Specimen Label: euxassay_009466_15
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_04
Specimen Label: euxassay_009466_04
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_05
Specimen Label: euxassay_009466_05
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_06
Specimen Label: euxassay_009466_06
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_07
Specimen Label: euxassay_009466_07
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_08
Specimen Label: euxassay_009466_08
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_09
Specimen Label: euxassay_009466_09
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_10
Specimen Label: euxassay_009466_10
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_11
Specimen Label: euxassay_009466_11
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_12
Specimen Label: euxassay_009466_12
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_13
Specimen Label: euxassay_009466_13
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_14
Specimen Label: euxassay_009466_14
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_15
Specimen Label: euxassay_009466_15
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_16
Specimen Label: euxassay_009466_16
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_18
Specimen Label: euxassay_009466_18
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_19
Specimen Label: euxassay_009466_19
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_20
Specimen Label: euxassay_009466_20
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1759823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_04
Specimen Label: euxassay_009466_04
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1759823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_05
Specimen Label: euxassay_009466_05
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1759823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_06
Specimen Label: euxassay_009466_06
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1759823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_07
Specimen Label: euxassay_009466_07
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1759823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_08
Specimen Label: euxassay_009466_08
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1759823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_16
Specimen Label: euxassay_009466_16
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1759823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_17
Specimen Label: euxassay_009466_17
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1759823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_18
Specimen Label: euxassay_009466_18
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:7540407
Age: embryonic day 14.5
Note: Rostral expression was greater than caudal.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6159696
Assay Type: RNA in situ
Annotation Date: 2018-06-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6159762
Age: postnatal week 10
Image: 1C ShcC
Specimen Label: 1C ShcC
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_11
Specimen Label: euxassay_009466_11
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_12
Specimen Label: euxassay_009466_12
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_16
Specimen Label: euxassay_009466_16
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_17
Specimen Label: euxassay_009466_17
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4944267
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4946258
Age: embryonic day 12.5
Image: 3 E12.5
Specimen Label: 3 E12.5
Detected: true
Specimen Num: 1
Publication
First Author: Ishii S
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription.
Volume: 101
Issue: 44
Pages: 15597-602
Publication
First Author: Luzi L
Year: 2000
Journal: Curr Opin Genet Dev
Title: Evolution of Shc functions from nematode to human.
Volume: 10
Issue: 6
Pages: 668-74
Publication
First Author: Hawley SP
Year: 2011
Journal: Dev Dyn
Title: Expression patterns of ShcD and Shc family adaptor proteins during mouse embryonic development.
Volume: 240
Issue: 1
Pages: 221-31
Publication
First Author: Garlow SJ
Year: 2005
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Allele
Name: src homology 2 domain-containing transforming protein C3; targeted mutation 1, Tony Pawson
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Genotype
Symbol: Shc3/Shc3
Background: involves: 129
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Shc3/Shc3<+>
Background: involves: 129
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Shc2/Shc2 Shc3/Shc3
Background: involves: 129
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Shc2/Shc2<+> Shc3/Shc3<+>
Background: involves: 129
Zygosity: cx
Has Mutant Allele: true
Protein Domain
Type: Family
Description: The SH2-containing Shc adapter proteins are targets of activated tyrosine kinases and are implicated in the transmission of activation signals to the Ras/mitogen-activated protein kinase (MAPK) pathway []. Three Shc genes were originally identified in mammals that encode proteins characterised by an amino-terminal phosphotyrosine binding (PTB) domain and a carboxy-terminal Src homology 2 domain. Shc1 (ShcA) is ubiquitously expressed, whereas expression of Shc2 (ShcB) and Shc3 (ShcC) appears to be limited to neuronal cells [].This entry represents Shc2.
Protein
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: false