|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 300 out of 1428 for Sirt1

<< First    < Previous  |  Next >    Last >>
0.032s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
28533219 | J:244387
 
First Author: Choi SE
Year: 2017
Journal: Mol Cell Biol
Title: Obesity-Linked Phosphorylation of SIRT1 by Casein Kinase 2 Inhibits Its Nuclear Localization and Promotes Fatty Liver.
Volume: 37
Issue: 15
•
•
•
•
•
Publication
34867800 | J:316582
 
First Author: Shtaif B
Year: 2021
Journal: Front Endocrinol (Lausanne)
Title: Anxiety and Cognition in Cre- Collagen Type II Sirt1 K/O Male Mice.
Volume: 12
Pages: 756909
•
•
•
•
•
Publication
32342656 | J:325258
First Author: Yang HY
Year: 2020
Journal: J Cell Mol Med
Title: The effect of Sirt1 deficiency on Ca2+ and Na+ regulation in mouse ventricular myocytes.
Volume: 24
Issue: 12
Pages: 6762-6772
•
•
•
•
•
Publication
24449278 | J:211212
First Author: Ou X
Year: 2014
Journal: Stem Cells
Title: SIRT1 positively regulates autophagy and mitochondria function in embryonic stem cells under oxidative stress.
Volume: 32
Issue: 5
Pages: 1183-94
•
•
•
•
•
Publication
30054388 | J:264507
 
First Author: Kumar A
Year: 2018
Journal: J Cell Sci
Title: A predicted unstructured C-terminal loop domain in SIRT1 is required for cathepsin B cleavage.
Volume: 131
Issue: 16
•
•
•
•
•
Publication
18987333 | J:146009
First Author: Kolthur-Seetharam U
Year: 2009
Journal: Biol Reprod
Title: The histone deacetylase SIRT1 controls male fertility in mice through regulation of hypothalamic-pituitary gonadotropin signaling.
Volume: 80
Issue: 2
Pages: 384-91
•
•
•
•
•
Publication
22006157 | J:180627
First Author: Purushotham A
Year: 2012
Journal: FASEB J
Title: Systemic SIRT1 insufficiency results in disruption of energy homeostasis and steroid hormone metabolism upon high-fat-diet feeding.
Volume: 26
Issue: 2
Pages: 656-67
•
•
•
•
•
Publication
33513830 | J:305379
 
First Author: Chou YT
Year: 2021
Journal: Int J Mol Sci
Title: Intestinal SIRT1 Deficiency-Related Intestinal Inflammation and Dysbiosis Aggravate TNFα-Mediated Renal Dysfunction in Cirrhotic Ascitic Mice.
Volume: 22
Issue: 3
•
•
•
•
•
Publication
23457303 | J:197948
First Author: Lu M
Year: 2013
Journal: J Biol Chem
Title: Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues.
Volume: 288
Issue: 15
Pages: 10722-35
•
•
•
•
•
Publication
29571747 | J:266606
First Author: Zhang Q
Year: 2018
Journal: Biochim Biophys Acta Gen Subj
Title: Cdk5 suppression blocks SIRT1 degradation via the ubiquitin-proteasome pathway in Parkinson's disease models.
Volume: 1862
Issue: 6
Pages: 1443-1451
•
•
•
•
•
Publication
31599935 | J:281732
First Author: Jin X
Year: 2019
Journal: Endocrinology
Title: Cartilage Ablation of Sirt1 Causes Inhibition of Growth Plate Chondrogenesis by Hyperactivation of mTORC1 Signaling.
Volume: 160
Issue: 12
Pages: 3001-3017
•
•
•
•
•
Publication
27634039 | J:237349
First Author: Bellet MM
Year: 2016
Journal: J Biol Chem
Title: Histone Deacetylase SIRT1 Controls Proliferation, Circadian Rhythm, and Lipid Metabolism during Liver Regeneration in Mice.
Volume: 291
Issue: 44
Pages: 23318-23329
•
•
•
•
•
Publication
29540553 | J:261203
First Author: Min SW
Year: 2018
Journal: J Neurosci
Title: SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.
Volume: 38
Issue: 15
Pages: 3680-3688
•
•
•
•
•
Publication
36136587 | J:331715
 
First Author: Zhang W
Year: 2022
Journal: J Clin Invest
Title: SIRT1 inactivation switches reactive astrocytes to an antiinflammatory phenotype in CNS autoimmunity.
Volume: 132
Issue: 22
•
•
•
•
•
Publication
20071779 | J:156677
First Author: Escande C
Year: 2010
Journal: J Clin Invest
Title: Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice.
Volume: 120
Issue: 2
Pages: 545-58
•
•
•
•
•
Publication
31145942 | J:275679
 
First Author: Yamamoto T
Year: 2019
Journal: J Mol Cell Cardiol
Title: Sirt1 counteracts decrease in membrane phospholipid unsaturation and diastolic dysfunction during saturated fatty acid overload.
Volume: 133
Pages: 1-11
•
•
•
•
•
Publication
23644469 | J:198936
First Author: Rafalski VA
Year: 2013
Journal: Nat Cell Biol
Title: Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain.
Volume: 15
Issue: 6
Pages: 614-24
•
•
•
•
•
Publication
32630813 | J:303400
 
First Author: Bulvik R
Year: 2020
Journal: Biomolecules
Title: SIRT1 Deficiency, Specifically in Fibroblasts, Decreases Apoptosis Resistance and Is Associated with Resolution of Lung-Fibrosis.
Volume: 10
Issue: 7
•
•
•
•
•
Publication
20139070 | J:161719
First Author: Hasegawa K
Year: 2010
Journal: J Biol Chem
Title: Kidney-specific overexpression of Sirt1 protects against acute kidney injury by retaining peroxisome function.
Volume: 285
Issue: 17
Pages: 13045-56
•
•
•
•
•
Publication
21947282 | J:178879
First Author: Peng L
Year: 2011
Journal: Mol Cell Biol
Title: SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities.
Volume: 31
Issue: 23
Pages: 4720-34
•
•
•
•
•
Publication
21474819 | J:185700
First Author: Li L
Year: 2011
Journal: Circ Res
Title: SIRT1 acts as a modulator of neointima formation following vascular injury in mice.
Volume: 108
Issue: 10
Pages: 1180-9
•
•
•
•
•
Publication
21964378 | J:196560
First Author: Kawashima T
Year: 2011
Journal: J Mol Cell Cardiol
Title: Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice.
Volume: 51
Issue: 6
Pages: 1026-36
•
•
•
•
•
Publication
27021582 | J:248698
 
First Author: Kim SY
Year: 2016
Journal: Arch Biochem Biophys
Title: Acetylome study in mouse adipocytes identifies targets of SIRT1 deacetylation in chromatin organization and RNA processing.
Volume: 598
Pages: 1-10
•
•
•
•
•
Publication
28254441 | J:250697
First Author: Inoue T
Year: 2017
Journal: Biochim Biophys Acta
Title: Omega-3 polyunsaturated fatty acids suppress the inflammatory responses of lipopolysaccharide-stimulated mouse microglia by activating SIRT1 pathways.
Volume: 1862
Issue: 5
Pages: 552-560
•
•
•
•
•
Publication
30771486 | J:275462
First Author: Di Emidio G
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: SIRT1 participates in the response to methylglyoxal-dependent glycative stress in mouse oocytes and ovary.
Volume: 1865
Issue: 6
Pages: 1389-1401
•
•
•
•
•
Publication
30552873 | J:277646
 
First Author: Cao M
Year: 2019
Journal: Arch Biochem Biophys
Title: Inhibition of SIRT1 by microRNA-9, the key point in process of LPS-induced severe inflammation.
Volume: 666
Pages: 148-155
•
•
•
•
•
Publication
27614878 | J:315583
First Author: Corpas R
Year: 2017
Journal: Mol Neurobiol
Title: SIRT1 Overexpression in Mouse Hippocampus Induces Cognitive Enhancement Through Proteostatic and Neurotrophic Mechanisms.
Volume: 54
Issue: 7
Pages: 5604-5619
•
•
•
•
•
Publication
29851253 | J:315609
First Author: Snyder-Warwick AK
Year: 2018
Journal: Aging Cell
Title: Hypothalamic Sirt1 protects terminal Schwann cells and neuromuscular junctions from age-related morphological changes.
Volume: 17
Issue: 4
Pages: e12776
•
•
•
•
•
Publication
34099590 | J:322073
First Author: Lai T
Year: 2021
Journal: Aging (Albany NY)
Title: Myeloid-specific SIRT1 deletion exacerbates airway inflammatory response in a mouse model of allergic asthma.
Volume: 13
Issue: 11
Pages: 15479-15490
•
•
•
•
•
Publication
30157481 | J:318524
First Author: Bai XZ
Year: 2018
Journal: Cell Physiol Biochem
Title: MicroRNA-138 Aggravates Inflammatory Responses of Macrophages by Targeting SIRT1 and Regulating the NF-κB and AKT Pathways.
Volume: 49
Issue: 2
Pages: 489-500
•
•
•
•
•
Publication
35158021 | J:326674
First Author: Yang Y
Year: 2022
Journal: Biochim Biophys Acta Mol Basis Dis
Title: SIRT1 attenuates neuroinflammation by deacetylating HSPA4 in a mouse model of Parkinson's disease.
Volume: 1868
Issue: 5
Pages: 166365
•
•
•
•
•
Publication
35906886 | J:345340
First Author: Zhou J
Year: 2022
Journal: Aging Cell
Title: Sirt1 overexpression improves senescence-associated pulmonary fibrosis induced by vitamin D deficiency through downregulating IL-11 transcription.
Volume: 21
Issue: 8
Pages: e13680
•
•
•
•
•
Publication
17964266 | -
First Author: Kim EJ
Year: 2007
Journal: Mol Cell
Title: Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity.
Volume: 28
Issue: 2
Pages: 277-90
•
•
•
•
•
Publication
23297412 | J:196087
First Author: Kuno A
Year: 2013
Journal: J Biol Chem
Title: Resveratrol improves cardiomyopathy in dystrophin-deficient mice through SIRT1 protein-mediated modulation of p300 protein.
Volume: 288
Issue: 8
Pages: 5963-72
•
•
•
•
•
Publication
27991597 | J:243450
 
First Author: Jablonska B
Year: 2016
Journal: Nat Commun
Title: Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury.
Volume: 7
Pages: 13866
•
•
•
•
•
Publication
31859031 | J:290619
First Author: Stoyas CA
Year: 2020
Journal: Neuron
Title: Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7.
Volume: 105
Issue: 4
Pages: 630-644.e9
•
•
•
•
•
Publication
18371449 | J:149804
First Author: Han MK
Year: 2008
Journal: Cell Stem Cell
Title: SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization.
Volume: 2
Issue: 3
Pages: 241-51
•
•
•
•
•
Publication
23791176 | J:200008
First Author: Chang HC
Year: 2013
Journal: Cell
Title: SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging.
Volume: 153
Issue: 7
Pages: 1448-60
•
•
•
•
•
Publication
30389922 | J:268698
First Author: Matsui S
Year: 2018
Journal: Nat Commun
Title: Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice.
Volume: 9
Issue: 1
Pages: 4604
•
•
•
•
•
Publication
19680552 | J:152462
First Author: Kang H
Year: 2009
Journal: PLoS One
Title: CK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage.
Volume: 4
Issue: 8
Pages: e6611
•
•
•
•
•
Publication
20647536 | J:164917
First Author: Schug TT
Year: 2010
Journal: Mol Cell Biol
Title: Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress.
Volume: 30
Issue: 19
Pages: 4712-21
•
•
•
•
•
Publication
25613939 | J:230981
First Author: Gao J
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: MicroRNA-204-5p-Mediated Regulation of SIRT1 Contributes to the Delay of Epithelial Cell Cycle Traversal in Diabetic Corneas.
Volume: 56
Issue: 3
Pages: 1493-504
•
•
•
•
•
Publication
27620389 | J:280533
First Author: Gao D
Year: 2016
Journal: Hypertension
Title: Activation of SIRT1 Attenuates Klotho Deficiency-Induced Arterial Stiffness and Hypertension by Enhancing AMP-Activated Protein Kinase Activity.
Volume: 68
Issue: 5
Pages: 1191-1199
•
•
•
•
•
Publication
24498364 | J:212845
First Author: Hah YS
Year: 2014
Journal: PLoS One
Title: Myeloid deletion of SIRT1 aggravates serum transfer arthritis in mice via nuclear factor-κB activation.
Volume: 9
Issue: 2
Pages: e87733
•
•
•
•
•
Publication
23821198 | J:214183
First Author: Zuo L
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: SIRT1 promotes RGC survival and delays loss of function following optic nerve crush.
Volume: 54
Issue: 7
Pages: 5097-102
•
•
•
•
•
Publication
36716673 | J:341705
 
First Author: Jiang T
Year: 2023
Journal: Redox Biol
Title: SIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc.
Volume: 60
Pages: 102615
•
•
•
•
•
Publication
28984870 | J:274045
First Author: Lee IC
Year: 2018
Journal: Cell Death Differ
Title: Oxidative stress promotes SIRT1 recruitment to the GADD34/PP1α complex to activate its deacetylase function.
Volume: 25
Issue: 2
Pages: 255-267
•
•
•
•
•
Publication
25763637 | J:222087
First Author: Orozco-Solis R
Year: 2015
Journal: Endocrinology
Title: SIRT1 Relays Nutritional Inputs to the Circadian Clock Through the Sf1 Neurons of the Ventromedial Hypothalamus.
Volume: 156
Issue: 6
Pages: 2174-84
•
•
•
•
•
Publication
24639483 | J:222762
First Author: Sin TK
Year: 2014
Journal: J Physiol
Title: Modulating effect of SIRT1 activation induced by resveratrol on Foxo1-associated apoptotic signalling in senescent heart.
Volume: 592
Issue: 12
Pages: 2535-48
•
•
•
•
•
Publication
27317762 | J:234337
First Author: Liu Z
Year: 2016
Journal: J Lipid Res
Title: Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice.
Volume: 57
Issue: 8
Pages: 1373-81
•
•
•
•
•
Publication
27693787 | J:240560
First Author: Hao Y
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Lin28a protects against postinfarction myocardial remodeling and dysfunction through Sirt1 activation and autophagy enhancement.
Volume: 479
Issue: 4
Pages: 833-840
•
•
•
•
•
Publication
26352206 | J:251178
First Author: Li J
Year: 2015
Journal: Biochim Biophys Acta
Title: Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation.
Volume: 1853
Issue: 11 Pt A
Pages: 2929-36
•
•
•
•
•
Publication
23834033 | J:318991
First Author: Choi SE
Year: 2013
Journal: Aging Cell
Title: Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT.
Volume: 12
Issue: 6
Pages: 1062-72
•
•
•
•
•
Publication
29178516 | J:329850
First Author: Khaidizar FD
Year: 2017
Journal: Genes Cells
Title: Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating SIRT1 activity and antioxidant gene expression in mouse cells.
Volume: 22
Issue: 12
Pages: 982-992
•
•
•
•
•
Publication
17201918 | J:121948
First Author: Li H
Year: 2007
Journal: Breast Cancer Res
Title: SirT1 modulates the estrogen-insulin-like growth factor-1 signaling for postnatal development of mammary gland in mice.
Volume: 9
Issue: 1
Pages: R1
•
•
•
•
•
Publication
24262277 | J:268875
First Author: Yin H
Year: 2014
Journal: Gastroenterology
Title: Deletion of SIRT1 from hepatocytes in mice disrupts lipin-1 signaling and aggravates alcoholic fatty liver.
Volume: 146
Issue: 3
Pages: 801-11
•
•
•
•
•
Publication
25973386 | J:270580
First Author: Mayoral R
Year: 2015
Journal: Mol Metab
Title: Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity.
Volume: 4
Issue: 5
Pages: 378-91
•
•
•
•
•
Publication
37670386 | J:340547
First Author: Yao K
Year: 2023
Journal: J Neuroinflammation
Title: Microglial SIRT1 activation attenuates synapse loss in retinal inner plexiform layer via mTORC1 inhibition.
Volume: 20
Issue: 1
Pages: 202
•
•
•
•
•
Publication
22078933 | J:179674
First Author: Qiang L
Year: 2011
Journal: Cell Metab
Title: Proatherogenic abnormalities of lipid metabolism in SirT1 transgenic mice are mediated through Creb deacetylation.
Volume: 14
Issue: 6
Pages: 758-67
•
•
•
•
•
Publication
20817729 | J:182476
First Author: Ponugoti B
Year: 2010
Journal: J Biol Chem
Title: SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism.
Volume: 285
Issue: 44
Pages: 33959-70
•
•
•
•
•
Publication
24141423 | J:203764
First Author: Hasegawa K
Year: 2013
Journal: Nat Med
Title: Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes.
Volume: 19
Issue: 11
Pages: 1496-504
•
•
•
•
•
Publication
21115502 | J:186032
First Author: Planavila A
Year: 2011
Journal: Cardiovasc Res
Title: Sirt1 acts in association with PPARα to protect the heart from hypertrophy, metabolic dysregulation, and inflammation.
Volume: 90
Issue: 2
Pages: 276-84
•
•
•
•
•
Publication
27711079 | J:274147
First Author: Cui X
Year: 2016
Journal: Cell Death Dis
Title: Inactivation of Sirt1 in mouse livers protects against endotoxemic liver injury by acetylating and activating NF-κB.
Volume: 7
Issue: 10
Pages: e2403
•
•
•
•
•
Publication
30746504 | J:307567
First Author: Rickert E
Year: 2019
Journal: J Endocr Soc
Title: Neuronal SIRT1 Regulates Metabolic and Reproductive Function and the Response to Caloric Restriction.
Volume: 3
Issue: 2
Pages: 427-445
•
•
•
•
•
Publication
25159328 | J:215559
First Author: White AT
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: High-fat diet-induced impairment of skeletal muscle insulin sensitivity is not prevented by SIRT1 overexpression.
Volume: 307
Issue: 9
Pages: E764-72
•
•
•
•
•
Publication
19470756 | J:151441
First Author: Rajamohan SB
Year: 2009
Journal: Mol Cell Biol
Title: SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1.
Volume: 29
Issue: 15
Pages: 4116-29
•
•
•
•
•
Publication
28558013 | J:243645
First Author: Cho JH
Year: 2017
Journal: PLoS Genet
Title: Downregulation of SIRT1 signaling underlies hepatic autophagy impairment in glycogen storage disease type Ia.
Volume: 13
Issue: 5
Pages: e1006819
•
•
•
•
•
Publication
17452443 | J:122786
First Author: Qiang L
Year: 2007
Journal: Mol Cell Biol
Title: Adiponectin secretion is regulated by SIRT1 and the endoplasmic reticulum oxidoreductase Ero1-L alpha.
Volume: 27
Issue: 13
Pages: 4698-707
•
•
•
•
•
Publication
17785417 | J:124959
First Author: Mattagajasingh I
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase.
Volume: 104
Issue: 37
Pages: 14855-60
•
•
•
•
•
Publication
21593185 | J:175266
First Author: Kim DH
Year: 2011
Journal: Am J Physiol Renal Physiol
Title: SIRT1 activation by resveratrol ameliorates cisplatin-induced renal injury through deacetylation of p53.
Volume: 301
Issue: 2
Pages: F427-35
•
•
•
•
•
Publication
22179316 | J:180782
First Author: Jeong H
Year: 2011
Journal: Nat Med
Title: Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway.
Volume: 18
Issue: 1
Pages: 159-65
•
•
•
•
•
Publication
32325423 | J:315655
 
First Author: Han Y
Year: 2020
Journal: Redox Biol
Title: SIRT1 agonism modulates cardiac NLRP3 inflammasome through pyruvate dehydrogenase during ischemia and reperfusion.
Volume: 34
Pages: 101538
•
•
•
•
•
Publication
37779142 | J:342131
First Author: Shin DH
Year: 2023
Journal: Exp Mol Med
Title: Oncogenic KRAS mutation confers chemoresistance by upregulating SIRT1 in non-small cell lung cancer.
Volume: 55
Issue: 10
Pages: 2220-2237
•
•
•
•
•
Publication
30786847 | J:293239
First Author: Gorski PA
Year: 2019
Journal: Circ Res
Title: Role of SIRT1 in Modulating Acetylation of the Sarco-Endoplasmic Reticulum Ca2+-ATPase in Heart Failure.
Volume: 124
Issue: 9
Pages: e63-e80
•
•
•
•
•
Publication
30452596 | J:266975
First Author: Lin Y
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: SIRT1 Deletion Impairs Retinal Endothelial Cell Migration Through Downregulation of VEGF-A/VEGFR-2 and MMP14.
Volume: 59
Issue: 13
Pages: 5431-5440
•
•
•
•
•
Publication
20668706 | J:163081
First Author: Akieda-Asai S
Year: 2010
Journal: PLoS One
Title: SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5Kgamma Activity through Deacetylation of Specific Lysine Residues in Mammals.
Volume: 5
Issue: 7
Pages: e11755
•
•
•
•
•
Publication
27255815 | J:234995
 
First Author: Han C
Year: 2016
Journal: Neurobiol Aging
Title: Sirt1 deficiency protects cochlear cells and delays the early onset of age-related hearing loss in C57BL/6 mice.
Volume: 43
Pages: 58-71
•
•
•
•
•
Publication
24278473 | J:209772
First Author: Clark-Knowles KV
Year: 2013
Journal: PLoS One
Title: SIRT1 catalytic activity has little effect on tumor formation and metastases in a mouse model of breast cancer.
Volume: 8
Issue: 11
Pages: e82106
•
•
•
•
•
Publication
24169546 | J:207716
First Author: Quinn LS
Year: 2014
Journal: Endocrinology
Title: IL-15 is required for postexercise induction of the pro-oxidative mediators PPARδ and SIRT1 in male mice.
Volume: 155
Issue: 1
Pages: 143-55
•
•
•
•
•
Publication
25948680 | J:246870
First Author: Qiao L
Year: 2015
Journal: Diabetes
Title: Maternal High-Fat Feeding Increases Placental Lipoprotein Lipase Activity by Reducing SIRT1 Expression in Mice.
Volume: 64
Issue: 9
Pages: 3111-20
•
•
•
•
•
Publication
17098745 | J:180466
First Author: Kume S
Year: 2007
Journal: J Biol Chem
Title: SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation.
Volume: 282
Issue: 1
Pages: 151-8
•
•
•
•
•
Publication
22546858 | J:188297
First Author: Yao H
Year: 2012
Journal: J Clin Invest
Title: SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice.
Volume: 122
Issue: 6
Pages: 2032-45
•
•
•
•
•
Publication
28069388 | J:323214
First Author: Chandel N
Year: 2017
Journal: Exp Mol Pathol
Title: Vitamin D receptor deficit induces activation of renin angiotensin system via SIRT1 modulation in podocytes.
Volume: 102
Issue: 1
Pages: 97-105
•
•
•
•
•
Publication
24633890 | J:211201
First Author: Yao H
Year: 2014
Journal: Am J Physiol Lung Cell Mol Physiol
Title: SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism.
Volume: 306
Issue: 9
Pages: L816-28
•
•
•
•
•
Publication
30581279 | J:311945
 
First Author: Jiang Y
Year: 2018
Journal: Mol Vis
Title: Epac1 deacetylates HMGB1 through increased IGFBP-3 and SIRT1 levels in the retinal vasculature.
Volume: 24
Pages: 727-732
•
•
•
•
•
Publication
20947830 | J:178511
First Author: Hariharan N
Year: 2010
Journal: Circ Res
Title: Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes.
Volume: 107
Issue: 12
Pages: 1470-82
•
•
•
•
•
Publication
34597611 | J:333928
First Author: Chhabra G
Year: 2022
Journal: J Invest Dermatol
Title: Antimelanoma Effects of Concomitant Inhibition of SIRT1 and SIRT3 in Braf(V600E)/Pten(NULL) Mice.
Volume: 142
Issue: 4
Pages: 1145-1157.e7
•
•
•
•
•
Publication
21081708 | J:172321
First Author: Wei D
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Feedback regulation of hepatic gluconeogenesis through modulation of SHP/Nr0b2 gene expression by Sirt1 and FoxO1.
Volume: 300
Issue: 2
Pages: E312-20
•
•
•
•
•
Publication
35134122 | J:330211
First Author: Hwang YJ
Year: 2022
Journal: Biol Reprod
Title: SIRT1 plays an important role in implantation and decidualization during mouse early pregnancy.
Volume: 106
Issue: 6
Pages: 1072-1082
•
•
•
•
•
Publication
24389307 | J:245857
First Author: Kazgan N
Year: 2014
Journal: Gastroenterology
Title: Intestine-specific deletion of SIRT1 in mice impairs DCoH2-HNF-1α-FXR signaling and alters systemic bile acid homeostasis.
Volume: 146
Issue: 4
Pages: 1006-16
•
•
•
•
•
Publication
30381838 | J:348451
First Author: Nguyen LT
Year: 2019
Journal: J Physiol
Title: SIRT1 overexpression attenuates offspring metabolic and liver disorders as a result of maternal high-fat feeding.
Volume: 597
Issue: 2
Pages: 467-480
•
•
•
•
•
Publication
16751189 | J:116473
First Author: Qin W
Year: 2006
Journal: J Biol Chem
Title: Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction.
Volume: 281
Issue: 31
Pages: 21745-54
•
•
•
•
•
Publication
20966168 | J:168412
First Author: Ou X
Year: 2011
Journal: Blood
Title: SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouse.
Volume: 117
Issue: 2
Pages: 440-50
•
•
•
•
•
Publication
20668205 | J:162852
First Author: Satoh A
Year: 2010
Journal: J Neurosci
Title: SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus.
Volume: 30
Issue: 30
Pages: 10220-32
•
•
•
•
•
Publication
28789977 | J:256233
First Author: Cheng J
Year: 2017
Journal: Biochim Biophys Acta
Title: Ablation of systemic SIRT1 activity promotes nonalcoholic fatty liver disease by affecting liver-mesenteric adipose tissue fatty acid mobilization.
Volume: 1863
Issue: 11
Pages: 2783-2790
•
•
•
•
•
Publication
29331532 | J:258112
 
First Author: Xu L
Year: 2018
Journal: Neuroscience
Title: High-fat Diet Mediates Anxiolytic-like Behaviors in a Time-dependent Manner Through the Regulation of SIRT1 in the Brain.
Volume: 372
Pages: 237-245
•
•
•
•
•
Publication
25104317 | J:326994
First Author: Mu W
Year: 2014
Journal: Sci China Life Sci
Title: Overexpression of a dominant-negative mutant of SIRT1 in mouse heart causes cardiomyocyte apoptosis and early-onset heart failure.
Volume: 57
Issue: 9
Pages: 915-24
•
•
•
•
•
Publication
22542455 | J:188021
First Author: Lin Z
Year: 2012
Journal: Mol Cell
Title: USP22 antagonizes p53 transcriptional activation by deubiquitinating Sirt1 to suppress cell apoptosis and is required for mouse embryonic development.
Volume: 46
Issue: 4
Pages: 484-94
•
•
•
•
•
Publication
25032964 | J:228605
First Author: Chalkiadaki A
Year: 2014
Journal: PLoS Genet
Title: Muscle-specific SIRT1 gain-of-function increases slow-twitch fibers and ameliorates pathophysiology in a mouse model of duchenne muscular dystrophy.
Volume: 10
Issue: 7
Pages: e1004490
•
•
•
•
•
Publication
25589773 | J:217723
First Author: Cho SH
Year: 2015
Journal: J Neurosci
Title: SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β.
Volume: 35
Issue: 2
Pages: 807-18
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom