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Slc12a8
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0.017s
Type
Details
Score
Publication
First Author:
Mouse Genome Informatics Scientific Curators
Year:
2005
Title:
Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
First Author:
Mouse Genome Informatics Scientific Curators
Year:
2009
Journal:
Database Download
Title:
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Organism:
Mus musculus/domesticus
Length:
914
Fragment?:
false
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Allele
Name:
solute carrier family 12 (potassium/chloride transporters), member 8; endonuclease-mediated mutation 2, Shin-ichiro Imai
Allele Type:
Endonuclease-mediated
Attribute String:
Inducible, Recombinase
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Publication
First Author:
Gagnon KB
Year:
2013
Journal:
Am J Physiol Cell Physiol
Title:
Physiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockouts.
Volume:
304
Issue:
8
Pages:
C693-714
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Protein Domain
Type:
Family
Description:
The electroneutral cation-chloride-coupled cotransporter gene family (SLC12) consists of nine members and encompasses two major branches. One brach includes three genes (SLC12A1-SLC12A3) encoding two bumetanide-sensitive Na+-K+-2Cl- cotransporters (NKC) and a thiazide-sensitive Na+:Cl- cotransporter (NC). The second branch includes four genes (SLC12A4-7) encoding electroneutral K+-Cl- cotransporters (KCC). The transported substrates of the remaining two SLC12 family members, SLC12A8 and SLC12A9, are unknown [].This entry represents SLC12A9. No physiological role has been ascribed to SLC12A9 [, ].
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Genotype
Symbol:
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Slc12a8/Slc12a8<+>
Background:
involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity:
cx
Has Mutant Allele:
true
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Genotype
Symbol:
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Slc12a8/Slc12a8<+>
Background:
involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity:
cn
Has Mutant Allele:
true
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Protein
Organism:
Mus musculus/domesticus
Length:
60
Fragment?:
true
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