| Type |
Details |
Score |
| Publication |
| First Author: |
Zhou Q |
| Year: |
2001 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Estrogen action and male fertility: roles of the sodium/hydrogen exchanger-3 and fluid reabsorption in reproductive tract function. |
| Volume: |
98 |
| Issue: |
24 |
| Pages: |
14132-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chou SY |
| Year: |
2016 |
| Journal: |
Nat Commun |
| Title: |
CLIC4 regulates apical exocytosis and renal tube luminogenesis through retromer- and actin-mediated endocytic trafficking. |
| Volume: |
7 |
|
| Pages: |
10412 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sizova D |
| Year: |
2013 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
Renalase regulates renal dopamine and phosphate metabolism. |
| Volume: |
305 |
| Issue: |
6 |
| Pages: |
F839-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bosse A |
| Year: |
2000 |
| Journal: |
Dev Dyn |
| Title: |
Identification of a novel mouse Iroquois homeobox gene, Irx5, and chromosomal localisation of all members of the mouse Iroquois gene family. |
| Volume: |
218 |
| Issue: |
1 |
| Pages: |
160-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nakamura K |
| Year: |
2002 |
| Journal: |
Am J Physiol Cell Physiol |
| Title: |
Endogenous and exogenous glucocorticoid regulation of ENaC mRNA expression in developing kidney and lung. |
| Volume: |
283 |
| Issue: |
3 |
| Pages: |
C762-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Siyanov V |
| Year: |
2013 |
| Journal: |
Biol Reprod |
| Title: |
NHE1 is the sodium-hydrogen exchanger active in acute intracellular pH regulation in preimplantation mouse embryos. |
| Volume: |
88 |
| Issue: |
6 |
| Pages: |
157 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shull GE |
| Year: |
2000 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
Lessons from genetically engineered animal models VIII. Absorption and secretion of ions in the gastrointestinal tract. |
| Volume: |
278 |
| Issue: |
2 |
| Pages: |
G185-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kühn R |
| Year: |
1993 |
| Journal: |
Cell |
| Title: |
Interleukin-10-deficient mice develop chronic enterocolitis. |
| Volume: |
75 |
| Issue: |
2 |
| Pages: |
263-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tan SH |
| Year: |
2020 |
| Journal: |
Nature |
| Title: |
AQP5 enriches for stem cells and cancer origins in the distal stomach. |
| Volume: |
578 |
| Issue: |
7795 |
| Pages: |
437-443 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nührenberg TG |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
Cardiac Myocyte De Novo DNA Methyltransferases 3a/3b Are Dispensable for Cardiac Function and Remodeling after Chronic Pressure Overload in Mice. |
| Volume: |
10 |
| Issue: |
6 |
| Pages: |
e0131019 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tamimi RM |
| Year: |
1997 |
| Journal: |
Genomics |
| Title: |
NEUROD2 and NEUROD3 genes map to human chromosomes 17q12 and 5q23-q31 and mouse chromosomes 11 and 13, respectively. |
| Volume: |
40 |
| Issue: |
2 |
| Pages: |
355-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Park JH |
| Year: |
2012 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Fibronectin stimulates migration through lipid raft dependent NHE-1 activation in mouse embryonic stem cells: involvement of RhoA, Ca(2+)/CaM, and ERK. |
| Volume: |
1820 |
| Issue: |
10 |
| Pages: |
1618-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gisler SM |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
Interaction of the type IIa Na/Pi cotransporter with PDZ proteins. |
| Volume: |
276 |
| Issue: |
12 |
| Pages: |
9206-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pathak BG |
| Year: |
1996 |
| Journal: |
Genomics |
| Title: |
Mouse chromosomal location of four Na/H exchanger isoform genes. |
| Volume: |
31 |
| Issue: |
2 |
| Pages: |
261-3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Weis VG |
| Year: |
2016 |
| Journal: |
Cell Mol Gastroenterol Hepatol |
| Title: |
Loss of MYO5B in mice recapitulates Microvillus Inclusion Disease and reveals an apical trafficking pathway distinct to neonatal duodenum. |
| Volume: |
2 |
| Issue: |
2 |
| Pages: |
131-157 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jeong HW |
| Year: |
2009 |
| Journal: |
J Clin Invest |
| Title: |
Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice. |
| Volume: |
119 |
| Issue: |
11 |
| Pages: |
3290-300 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
De Arcangelis A |
| Year: |
2017 |
| Journal: |
Gut |
| Title: |
Hemidesmosome integrity protects the colon against colitis and colorectal cancer. |
| Volume: |
66 |
| Issue: |
10 |
| Pages: |
1748-1760 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Trinh LT |
| Year: |
2025 |
| Journal: |
Development |
| Title: |
Positive autoregulation of Sox17 is necessary for gallbladder and extrahepatic bile duct formation. |
| Volume: |
152 |
| Issue: |
2 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Oh Y |
| Year: |
2023 |
| Journal: |
Biol Reprod |
| Title: |
Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice†. |
| Volume: |
109 |
| Issue: |
4 |
| Pages: |
520-532 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Toronto Centre for Phenogenomics |
| Year: |
2013 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Willnow T |
| Year: |
2005 |
| Journal: |
Organogenesis |
| Title: |
The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease. |
| Volume: |
2 |
| Issue: |
2 |
| Pages: |
42-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shanghai Model Organisms Center |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mammalian Functional Genomics Centre |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dickinson ME |
| Year: |
2016 |
| Journal: |
Nature |
| Title: |
High-throughput discovery of novel developmental phenotypes. |
| Volume: |
537 |
| Issue: |
7621 |
| Pages: |
508-514 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Knockout Mouse Consortium |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lennon G |
| Year: |
1999 |
| Journal: |
Database Download |
| Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GUDMAP Consortium |
| Year: |
2004 |
| Journal: |
www.gudmap.org |
| Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE10740 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Allele |
| Name: |
solute carrier family 9 (sodium/hydrogen exchanger), member 3; targeted mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Scott RO |
| Year: |
2002 |
| Journal: |
J Biol Chem |
| Title: |
A novel PDZ protein regulates the activity of guanylyl cyclase C, the heat-stable enterotoxin receptor. |
| Volume: |
277 |
| Issue: |
25 |
| Pages: |
22934-41 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Na(+)/H(+) exchange regulatory cofactor NHERF-4 is PDZ domain containing protein that regulates the activity of guanylyl cyclase C, the heat-stable enterotoxin receptor []. It stimulates SLC9A3 (NHE3) activity in the presence of elevated calcium ions []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hoshii T |
| Year: |
2007 |
| Journal: |
Biol Reprod |
| Title: |
LGR4 regulates the postnatal development and integrity of male reproductive tracts in mice. |
| Volume: |
76 |
| Issue: |
2 |
| Pages: |
303-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang J |
| Year: |
2019 |
| Journal: |
Sci Rep |
| Title: |
Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
17220 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yao G |
| Year: |
2017 |
| Journal: |
Endocrinology |
| Title: |
Genome-Wide Mapping of In Vivo ERα-Binding Sites in Male Mouse Efferent Ductules. |
| Volume: |
158 |
| Issue: |
11 |
| Pages: |
3724-3737 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Joseph A |
| Year: |
2010 |
| Journal: |
Biol Reprod |
| Title: |
Absence of estrogen receptor alpha leads to physiological alterations in the mouse epididymis and consequent defects in sperm function. |
| Volume: |
82 |
| Issue: |
5 |
| Pages: |
948-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Engevik AC |
| Year: |
2018 |
| Journal: |
Gastroenterology |
| Title: |
Loss of MYO5B Leads to Reductions in Na(+) Absorption With Maintenance of CFTR-Dependent Cl(-) Secretion in Enterocytes. |
| Volume: |
155 |
| Issue: |
6 |
| Pages: |
1883-1897.e10 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
498
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
498
 |
| Fragment?: |
false |
|
•
•
•
•
•
|