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Search results 201 to 300 out of 327 for Slitrk2

0.015s
Type Details Score
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_11
Specimen Label: euxassay_012159_11
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_12
Specimen Label: euxassay_012159_12
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_13
Specimen Label: euxassay_012159_13
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_14
Specimen Label: euxassay_012159_14
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_15
Specimen Label: euxassay_012159_15
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:2680191
Assay Type: RNA in situ
Annotation Date: 2003-12-01
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:2680224
Age: embryonic day 11.5
Specimen Label: 4b
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4882492
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4945200
Age: embryonic day 11.5
Image: g00669 E11.5
Note: Expression was region specific and scattered.
Specimen Label: g00669 E11.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4882492
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3266028
Stage: TS28
Assay Id: MGI:4945200
Age: postnatal day 7
Image: g00669 P7
Specimen Label: g00669 P7
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:4882492
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3266028
Stage: TS28
Assay Id: MGI:4945200
Age: postnatal day 42
Image: g00669 Adult
Specimen Label: g00669 Adult
Detected: false
Specimen Num: 4
GXD Expression  
Probe: MGI:2680191
Assay Type: RNA in situ
Annotation Date: 2003-12-01
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1758222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:2680224
Age: embryonic day 14.5
Note: Expression was strong in the ventral motor columns.
Specimen Label: 4d
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2018-07-06
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:2692222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6164609
Age: embryonic day 14.5
Specimen Label: Table S7 - E14.5
Specimen Num: 1
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_03
Specimen Label: euxassay_012159_03
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_04
Specimen Label: euxassay_012159_04
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_05
Specimen Label: euxassay_012159_05
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_06
Specimen Label: euxassay_012159_06
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_07
Specimen Label: euxassay_012159_07
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_08
Specimen Label: euxassay_012159_08
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_16
Specimen Label: euxassay_012159_16
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_17
Specimen Label: euxassay_012159_17
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_18
Specimen Label: euxassay_012159_18
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_19
Specimen Label: euxassay_012159_19
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_20
Specimen Label: euxassay_012159_20
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_21
Specimen Label: euxassay_012159_21
Detected: true
Specimen Num: 20
GXD Expression
Probe: MGI:4400941
Assay Type: RNA in situ
Annotation Date: 2014-08-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5578585
Age: embryonic day 18.5
Image: 9B
Note: Expressed in subsets of cell bodies.
Specimen Label: 9B
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:2680191
Assay Type: RNA in situ
Annotation Date: 2003-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754025
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:2680224
Age: embryonic day 17.0
Specimen Label: 3b
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:4882492
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945200
Age: postnatal day 7
Image: g00669 P7
Note: Expression was region specific and scattered.
Specimen Label: g00669 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4882492
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945200
Age: postnatal day 42
Image: g00669 Adult
Specimen Label: g00669 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_03
Specimen Label: euxassay_012159_03
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_04
Specimen Label: euxassay_012159_04
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_05
Specimen Label: euxassay_012159_05
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_19
Specimen Label: euxassay_012159_19
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_20
Specimen Label: euxassay_012159_20
Detected: true
Specimen Num: 19
GXD Expression
Probe: MGI:4882492
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945200
Age: embryonic day 15.5
Image: g00669 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00669 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4882492
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945200
Age: postnatal day 7
Image: g00669 P7
Specimen Label: g00669 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4882492
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945200
Age: postnatal day 42
Image: g00669 Adult
Note: Expression was region specific and scattered.
Specimen Label: g00669 Adult
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4400941
Assay Type: RNA in situ
Annotation Date: 2014-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5578585
Age: embryonic day 18.5
Image: 2B
Note: Expressed in cells lining the olfactory ventricule, in the glomerular layer, and at low levels in the olfactory nerve layer.
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4400941
Assay Type: RNA in situ
Annotation Date: 2014-08-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:5578585
Age: postnatal day 10
Image: 2H
Specimen Label: 2H
Detected: false
Specimen Num: 3
GXD Expression  
Probe: MGI:2680191
Assay Type: RNA in situ
Annotation Date: 2003-12-01
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1715219
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:2680224
Age: embryonic day 11.5
Note: Expression was strong on the ventral side.
Specimen Label: 4b
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4882492
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945200
Age: embryonic day 15.5
Image: g00669 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00669 E15.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4400941
Assay Type: RNA in situ
Annotation Date: 2014-08-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1761226
Stage: TS26
Assay Id: MGI:5578585
Age: embryonic day 18.5
Specimen Label: not shown
Detected: false
Specimen Num: 13
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_06
Specimen Label: euxassay_012159_06
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_07
Specimen Label: euxassay_012159_07
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_18
Specimen Label: euxassay_012159_18
Detected: true
Specimen Num: 17
GXD Expression    
Probe: MGI:2680191
Assay Type: RNA in situ
Annotation Date: 2003-12-01
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270725
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:2680224
Age: embryonic day 17.0
Specimen Label: 3h
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4400941
Assay Type: RNA in situ
Annotation Date: 2014-08-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5578585
Age: embryonic day 18.5
Image: 3C
Note: Expressed in the basal layer.
Specimen Label: 3C
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4882492
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945200
Age: embryonic day 15.5
Image: g00669 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00669 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4882492
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945200
Age: postnatal day 7
Image: g00669 P7
Note: Expression was region specific and scattered.
Specimen Label: g00669 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4882492
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945200
Age: postnatal day 42
Image: g00669 Adult
Note: Expression was region specific and scattered.
Specimen Label: g00669 Adult
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4400941
Assay Type: RNA in situ
Annotation Date: 2014-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5578585
Age: embryonic day 18.5
Image: 8B
Note: Expressed in the gray matter. Higher levels of expression are observed in the ventral part where motor neurons are located.
Specimen Label: 8B
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4424023
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828305
Age: embryonic day 14.5
Image: euxassay_012159_07
Specimen Label: euxassay_012159_07
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3609760
Assay Type: RNA in situ
Annotation Date: 2006-01-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3610165
Age: embryonic day 14.5
Specimen Label: 1 slitrk E14.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3609760
Assay Type: RNA in situ
Annotation Date: 2006-01-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3610165
Age: embryonic day 16.5
Specimen Label: 1 slitrk E16.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4400941
Assay Type: RNA in situ
Annotation Date: 2014-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Pattern: Widespread
Stage: TS26
Assay Id: MGI:5578585
Age: embryonic day 18.5
Image: 1B
Note: Expressed widely in the brain. Highly expressed in the neuroepithelium.
Specimen Label: 1B
Detected: true
Specimen Num: 1
Publication
First Author: Han KA
Year: 2019
Journal: Sci Rep
Title: Slitrk2 controls excitatory synapse development via PDZ-mediated protein interactions.
Volume: 9
Issue: 1
Pages: 17094
Publication
First Author: Morimoto K
Year: 2020
Journal: Sci Rep
Title: Reverse genetics reveals single gene of every candidate on Hybrid sterility, X Chromosome QTL 2 (Hstx2) are dispensable for spermatogenesis.
Volume: 10
Issue: 1
Pages: 9060
Publication  
First Author: Aruga J
Year: 2003
Journal: Gene
Title: Human SLITRK family genes: genomic organization and expression profiling in normal brain and brain tumor tissue.
Volume: 315
Pages: 87-94
Publication
First Author: Beaubien F
Year: 2009
Journal: Dev Dyn
Title: Differential expression of Slitrk family members in the mouse nervous system.
Volume: 238
Issue: 12
Pages: 3285-96
Publication  
First Author: Matsumoto Y
Year: 2024
Journal: Front Mol Neurosci
Title: Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala.
Volume: 17
Pages: 1386924
Publication
First Author: Um JW
Year: 2014
Journal: Cell Rep
Title: Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.
Volume: 6
Issue: 6
Pages: 1096-1109
Publication
First Author: Yoshida Y
Year: 2006
Journal: Neuron
Title: PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.
Volume: 52
Issue: 5
Pages: 775-88
Publication
First Author: Jensen P
Year: 2004
Journal: Brain Res Mol Brain Res
Title: A neurogenomics approach to gene expression analysis in the developing brain.
Volume: 132
Issue: 2
Pages: 116-27
Publication
First Author: Memic F
Year: 2018
Journal: Gastroenterology
Title: Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Volume: 154
Issue: 3
Pages: 624-636
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Genotype
Symbol: Slitrk2/? Tg(Nes-cre)1Atp/?
Background: involves: C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
DO Term
Publication  
First Author: Beaubien F
Year: 2016
Journal: Sci Rep
Title: Slitrk1 is localized to excitatory synapses and promotes their development.
Volume: 6
Pages: 27343
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Protein
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: true
Publication  
First Author: Won SY
Year: 2019
Journal: Curr Opin Struct Biol
Title: Synaptic organizer: Slitrks and type IIa receptor protein tyrosine phosphatases.
Volume: 54
Pages: 95-103
Publication
First Author: Yim YS
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases.
Volume: 110
Issue: 10
Pages: 4057-62
Publication
First Author: Won SY
Year: 2018
Journal: Mol Cells
Title: Structural Basis for LAR-RPTP-Mediated Synaptogenesis.
Volume: 41
Issue: 7
Pages: 622-630
Publication
First Author: Wallace MJ
Year: 1998
Journal: Mol Cell Biol
Title: The second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigma.
Volume: 18
Issue: 5
Pages: 2608-16
Publication
First Author: Um JW
Year: 2013
Journal: Trends Cell Biol
Title: LAR-RPTPs: synaptic adhesion molecules that shape synapse development.
Volume: 23
Issue: 10
Pages: 465-75
Publication
First Author: Tomita H
Year: 2020
Journal: Cell Rep
Title: The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis.
Volume: 30
Issue: 1
Pages: 215-228.e5
Publication  
First Author: Han KA
Year: 2016
Journal: Int Rev Cell Mol Biol
Title: Emergent Synapse Organizers: LAR-RPTPs and Their Companions.
Volume: 324
Pages: 39-65
Protein Domain
Type: Family
Description: The Slitrk family comprises six vertebrate members (Slitrk1-6) that are highly expressed in the central nervous system (CNS), where they modulate neurite outgrowth. In humans, Slitrk1-6 are neuronal transmembrane proteins and are key synapse organizers at neuronal synapses through interactions with specific members of the presynaptic type IIa receptor protein tyrosine phosphatase (RPTP) family []. They contain two consecutive extracellular LRR modules, LRR1 and LRR2, and a single transmembrane domain, followed by an intracellular domain that is homologous to Trks. Mutations in human SLITRKs have been implicated in several neuropsychiatric disorders, including Tourette's syndrome, schizophrenia, trichotillomania and obsessive-compulsive disorder (OCD) []. Slitrk1 and Slitrk2 have been shown to regulate synapse formation between hippocampal neurons [].
Protein Domain
Type: Domain
Description: Receptor-type tyrosine-protein phosphatase delta (R-PTP-delta, also known as PTPRD), belongs to the LAR (leukocyte common antigen-related) family of receptor-type tyrosine-protein phosphatases (RPTPs), which belong to the larger family of classical tyrosine-specific protein tyrosine phosphatases (PTPs). PTPs () catalyze the dephosphorylation of phosphotyrosine peptides. LAR-RPTPs are synaptic adhesion molecules that play roles in various aspects of neuronal development, including axon guidance, neurite extension, and synapse formation and function [, , ]. PTPRD is involved in pre-synaptic differentiation through interaction with SLITRK2 [, ]. It contains an extracellular region with three immunoglobulin-like (Ig) domains and four to eight fibronectin type III (FN3) repeats (determined by alternative splicing), a single transmembrane domain, followed by an intracellular region with a membrane-proximal catalytic PTP domain (repeat 1, also called D1) and a membrane-distal non-catalytic PTP-like domain (repeat 2, also called D2) [, , ].This entry represents the catalytic PTP domain (repeat 1) found in the protein PTPRD from chordates.