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Search results 201 to 265 out of 265 for Smc1a

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Type Details Score
HT Sample
GSM1036116 1
       
Organism Name: mouse, laboratory
Notes: Smc1a binding
Curation Status: Not curated (Different assay type)
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HT Sample
GSM1036119 1
       
Organism Name: mouse, laboratory
Notes: Smc1a binding
Curation Status: Not curated (Different assay type)
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HT Sample
GSM1036127 1
       
Organism Name: mouse, laboratory
Notes: Smc1a binding
Curation Status: Not curated (Different assay type)
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HT Sample
GSM1036128 1
       
Organism Name: mouse, laboratory
Notes: Smc1a binding
Curation Status: Not curated (Different assay type)
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HT Sample
GSM1036129 1
       
Organism Name: mouse, laboratory
Notes: Smc1a binding
Curation Status: Not curated (Different assay type)
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HT Sample
GSM1036130 1
       
Organism Name: mouse, laboratory
Notes: Smc1a binding
Curation Status: Not curated (Different assay type)
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HT Sample
GSM1036133 1
       
Organism Name: mouse, laboratory
Notes: Smc1a binding
Curation Status: Not curated (Different assay type)
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Publication
34746147 | J:314268
 
First Author: Akagawa R
Year: 2021
Journal: Front Cell Dev Biol
Title: Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons.
Volume: 9
Pages: 753175
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Publication
22560297 | J:184521
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
18996922 | -
First Author: Revenkova E
Year: 2009
Journal: Hum Mol Genet
Title: Cornelia de Lange syndrome mutations in SMC1A or SMC3 affect binding to DNA.
Volume: 18
Issue: 3
Pages: 418-27
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Publication
24756084 | -
First Author: Parenti I
Year: 2014
Journal: Epigenetics
Title: Overall and allele-specific expression of the SMC1A gene in female Cornelia de Lange syndrome patients and healthy controls.
Volume: 9
Issue: 7
Pages: 973-9
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Publication
23106691 | -
First Author: Gimigliano A
Year: 2012
Journal: J Proteome Res
Title: Proteomic profile identifies dysregulated pathways in Cornelia de Lange syndrome cells with distinct mutations in SMC1A and SMC3 genes.
Volume: 11
Issue: 12
Pages: 6111-23
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HT Experiment
E-GEOD-42237 | The genomic landscape of cohesin-associated chromatin interactions
Series Id: GSE42237
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
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DO Term
DOID:0080506 | Cornelia de Lange syndrome 2
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Allele
Col1a1<tm2(tetO-GFP/RNAi:Smc1a)Iaai> | MGI:5911565
Name: collagen, type I, alpha 1; targeted mutation 2, Iannis Aifantis
Allele Type: Targeted
Attribute String: Inducible, Knockdown, Reporter
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DO Term
DOID:0070380 | developmental and epileptic encephalopathy 85
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Genotype
Genotype
Symbol: Col1a1/Col1a1<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Col1a1/Col1a1 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
11877377 | -
First Author: Yazdi PT
Year: 2002
Journal: Genes Dev
Title: SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint.
Volume: 16
Issue: 5
Pages: 571-82
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Publication
22885700 | -
First Author: Deardorff MA
Year: 2012
Journal: Nature
Title: HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle.
Volume: 489
Issue: 7415
Pages: 313-7
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Publication
8392064 | -
First Author: Jessberger R
Year: 1993
Journal: J Biol Chem
Title: A mammalian protein complex that repairs double-strand breaks and deletions by recombination.
Volume: 268
Issue: 20
Pages: 15070-9
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Publication
28301465 | -
First Author: Chao LF
Year: 2017
Journal: PLoS Genet
Title: An SMC-like protein binds and regulates Caenorhabditis elegans condensins.
Volume: 13
Issue: 3
Pages: e1006614
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Protein Domain
IPR029683 | SMC1A_metazoan
Type: Family
Description: Structural maintenance of chromosomes protein 1A (SMC1A) is a homologue of the yeast Smc1 protein, which is a component of the cohesin complex required for sister chromatid cohesion []. In human, it is part of the core cohesion complex composed of SMC1A, SMC3, RAD21 and STAG proteins []. These proteins form a ring structure that encircles sister chromatids to mediate sister chromatid cohesion []. SMC1A binds to SMC3 through its hinge domain []. Besides sister chromatid cohesion function, SMC1A-SMC3 heterodimer can also found in the RC-1 complex, a mammalian protein complex that promotes repair of DNA gaps and deletions through recombination [, ]. This entry also includes Smc1 homologue from Caenorhabditis elegans, SMCL-1. Unlike canonical SMC proteins, SMCL-1 lacks hinge and coil domains, and its ATPase domain lacks conserved amino acids required for ATP hydrolysis []. Mutations in SMC1A gene cause Cornelia de Lange syndrome 2 (CDLS2), which is a form of Cornelia de Lange syndrome, a clinically heterogeneous developmental disorder associated with malformations affecting multiple systems [, ].
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Publication
28116354 | J:258185
First Author: Li Z
Year: 2017
Journal: Sci Adv
Title: ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis.
Volume: 3
Issue: 1
Pages: e1601602
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Publication
37939182 | J:342398
First Author: Chatzinikolaou G
Year: 2023
Journal: Sci Adv
Title: XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes.
Volume: 9
Issue: 45
Pages: eadi2095
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HT Experiment
GSE234064 | Unexpected nuclear hormone receptor and chromatin dynamics regulate estrous cycle dependent gene expression [RNA-seq]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
26438359 | J:229031
First Author: Mullenders J
Year: 2015
Journal: J Exp Med
Title: Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms.
Volume: 212
Issue: 11
Pages: 1833-50
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Publication
32321712 | J:288307
 
First Author: Ou MY
Year: 2020
Journal: Development
Title: Heterogeneous nuclear ribonucleoprotein A3 controls mitotic progression of neural progenitors via interaction with cohesin.
Volume: 147
Issue: 10
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Protein
Q6A0B0
Organism: Mus musculus/domesticus
Length: 236  
Fragment?: true
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Protein
Q6PIE1
Organism: Mus musculus/domesticus
Length: 831  
Fragment?: true
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Protein
A0JLM6
Organism: Mus musculus/domesticus
Length: 679  
Fragment?: true
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Protein
Q9CU62
Organism: Mus musculus/domesticus
Length: 1233  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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