|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 300 out of 998 for Snca

<< First    < Previous  |  Next >    Last >>
0.027s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
22045698 | J:179713
First Author: Tomás-Zapico C
Year: 2012
Journal: Hum Mol Genet
Title: α-Synuclein accumulates in huntingtin inclusions but forms independent filaments and its deficiency attenuates early phenotype in a mouse model of Huntington's disease.
Volume: 21
Issue: 3
Pages: 495-510
•
•
•
•
•
Publication
18053987 | J:134020
First Author: Alvarez-Fischer D
Year: 2008
Journal: Exp Neurol
Title: Characterization of the striatal 6-OHDA model of Parkinson's disease in wild type and alpha-synuclein-deleted mice.
Volume: 210
Issue: 1
Pages: 182-93
•
•
•
•
•
Publication
26719256 | J:230514
First Author: Beatman EL
Year: 2015
Journal: J Virol
Title: Alpha-Synuclein Expression Restricts RNA Viral Infections in the Brain.
Volume: 90
Issue: 6
Pages: 2767-82
•
•
•
•
•
Publication
23161999 | J:191204
First Author: Luk KC
Year: 2012
Journal: Science
Title: Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice.
Volume: 338
Issue: 6109
Pages: 949-53
•
•
•
•
•
Publication
21734300 | J:174555
First Author: Lim Y
Year: 2011
Journal: J Neurosci
Title: α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies.
Volume: 31
Issue: 27
Pages: 10076-87
•
•
•
•
•
Publication
12388586 | J:79784
First Author: Cabin DE
Year: 2002
Journal: J Neurosci
Title: Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein.
Volume: 22
Issue: 20
Pages: 8797-807
•
•
•
•
•
Publication
19361478 | J:148932
First Author: Watson JB
Year: 2009
Journal: Neuroscience
Title: Alterations in corticostriatal synaptic plasticity in mice overexpressing human alpha-synuclein.
Volume: 159
Issue: 2
Pages: 501-13
•
•
•
•
•
Publication
17035541 | J:113229
First Author: Austin SA
Year: 2006
Journal: J Neurosci
Title: Alpha-synuclein expression modulates microglial activation phenotype.
Volume: 26
Issue: 41
Pages: 10558-63
•
•
•
•
•
Publication
28117497 | J:268174
First Author: Sarafian TA
Year: 2017
Journal: J Neurosci Res
Title: Stimulation of synaptoneurosome glutamate release by monomeric and fibrillated α-synuclein.
Volume: 95
Issue: 9
Pages: 1871-1887
•
•
•
•
•
Publication
23667637 | J:202180
First Author: Sarafian TA
Year: 2013
Journal: PLoS One
Title: Impairment of mitochondria in adult mouse brain overexpressing predominantly full-length, N-terminally acetylated human α-synuclein.
Volume: 8
Issue: 5
Pages: e63557
•
•
•
•
•
Publication
16260631 | J:102361
First Author: Ellis CE
Year: 2005
Journal: Mol Cell Biol
Title: Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein.
Volume: 25
Issue: 22
Pages: 10190-201
•
•
•
•
•
Publication
21091473 | J:170263
First Author: Steidinger TU
Year: 2011
Journal: J Neurochem
Title: A neuroprotective role for angiogenin in models of Parkinson's disease.
Volume: 116
Issue: 3
Pages: 334-41
•
•
•
•
•
Publication
16734431 | J:109641
First Author: Golovko MY
Year: 2006
Journal: Biochemistry
Title: Acyl-CoA synthetase activity links wild-type but not mutant alpha-synuclein to brain arachidonate metabolism.
Volume: 45
Issue: 22
Pages: 6956-66
•
•
•
•
•
Publication
15938614 | J:99690
First Author: Golovko MY
Year: 2005
Journal: Biochemistry
Title: Alpha-synuclein gene deletion decreases brain palmitate uptake and alters the palmitate metabolism in the absence of alpha-synuclein palmitate binding.
Volume: 44
Issue: 23
Pages: 8251-9
•
•
•
•
•
Publication
11359883 | J:69529
First Author: Rathke-Hartlieb S
Year: 2001
Journal: J Neurochem
Title: Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice.
Volume: 77
Issue: 4
Pages: 1181-4
•
•
•
•
•
Publication
16872721 | J:128051
First Author: Freichel C
Year: 2007
Journal: Neurobiol Aging
Title: Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice.
Volume: 28
Issue: 9
Pages: 1421-35
•
•
•
•
•
Publication
12438441 | J:80181
First Author: Neumann M
Year: 2002
Journal: J Clin Invest
Title: Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies.
Volume: 110
Issue: 10
Pages: 1429-39
•
•
•
•
•
Publication
19272424 | J:149844
First Author: Schell H
Year: 2009
Journal: Neuroscience
Title: Nuclear and neuritic distribution of serine-129 phosphorylated alpha-synuclein in transgenic mice.
Volume: 160
Issue: 4
Pages: 796-804
•
•
•
•
•
Publication
11733371 | J:100981
First Author: Kahle PJ
Year: 2001
Journal: Am J Pathol
Title: Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model.
Volume: 159
Issue: 6
Pages: 2215-25
•
•
•
•
•
Publication
30092270 | J:268718
 
First Author: Paiva I
Year: 2018
Journal: Neurobiol Dis
Title: Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function.
Volume: 119
Pages: 121-135
•
•
•
•
•
Publication
12062037 | J:76657
First Author: Giasson BI
Year: 2002
Journal: Neuron
Title: Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.
Volume: 34
Issue: 4
Pages: 521-33
•
•
•
•
•
Publication
25209277 | J:310696
First Author: Sacino AN
Year: 2014
Journal: J Neurosci
Title: Brain injection of α-synuclein induces multiple proteinopathies, gliosis, and a neuronal injury marker.
Volume: 34
Issue: 37
Pages: 12368-78
•
•
•
•
•
Publication
38822421 | J:349176
First Author: Choi SG
Year: 2024
Journal: Acta Neuropathol Commun
Title: Alpha-synuclein aggregates are phosphatase resistant.
Volume: 12
Issue: 1
Pages: 84
•
•
•
•
•
Publication
29976670 | J:277499
 
First Author: Ayers JI
Year: 2018
Journal: J Virol
Title: Localized Induction of Wild-Type and Mutant Alpha-Synuclein Aggregation Reveals Propagation along Neuroanatomical Tracts.
Volume: 92
Issue: 18
•
•
•
•
•
Publication
33632316 | J:327681
First Author: Ferreira N
Year: 2021
Journal: Acta Neuropathol Commun
Title: Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain.
Volume: 9
Issue: 1
Pages: 31
•
•
•
•
•
Publication
25002524 | J:212256
First Author: Sacino AN
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.
Volume: 111
Issue: 29
Pages: 10732-7
•
•
•
•
•
Publication
21445308 | J:171676
First Author: Wills J
Year: 2011
Journal: PLoS One
Title: Tauopathic changes in the striatum of A53T α-synuclein mutant mouse model of Parkinson's disease.
Volume: 6
Issue: 3
Pages: e17953
•
•
•
•
•
Publication
22537068 | J:186510
First Author: Xie W
Year: 2012
Journal: J Neurochem
Title: Alpha-synuclein impairs normal dynamics of mitochondria in cell and animal models of Parkinson's disease.
Volume: 122
Issue: 2
Pages: 404-14
•
•
•
•
•
Publication
29355568 | J:339101
 
First Author: Wang W
Year: 2018
Journal: Neurochem Int
Title: Genomic DNA levels of mutant alpha-synuclein correlate with non-motor symptoms in an A53T Parkinson's disease mouse model.
Volume: 114
Pages: 71-79
•
•
•
•
•
Publication
34572500 | J:339102
 
First Author: Ma X
Year: 2021
Journal: Biomolecules
Title: Blood-Derived α-Synuclein Aggregated in the Substantia Nigra of Parabiotic Mice.
Volume: 11
Issue: 9
•
•
•
•
•
Publication
23560093 | J:199878
First Author: Oaks AW
Year: 2013
Journal: PLoS One
Title: Age-dependent effects of A53T alpha-synuclein on behavior and dopaminergic function.
Volume: 8
Issue: 4
Pages: e60378
•
•
•
•
•
Publication
32017806 | J:292673
First Author: Woerman AL
Year: 2020
Journal: PLoS Pathog
Title: Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy.
Volume: 16
Issue: 2
Pages: e1008222
•
•
•
•
•
Publication
24117685 | J:206612
First Author: Farrell KF
Year: 2014
Journal: J Neurochem
Title: Non-motor parkinsonian pathology in aging A53T α-synuclein mice is associated with progressive synucleinopathy and altered enzymatic function.
Volume: 128
Issue: 4
Pages: 536-46
•
•
•
•
•
Publication
20152114 | J:167658
First Author: Nemani VM
Year: 2010
Journal: Neuron
Title: Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis.
Volume: 65
Issue: 1
Pages: 66-79
•
•
•
•
•
Publication
11442360 | J:70209
First Author: Matsuoka Y
Year: 2001
Journal: Neurobiol Dis
Title: Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter.
Volume: 8
Issue: 3
Pages: 535-9
•
•
•
•
•
Publication
10678833 | J:60638
First Author: Masliah E
Year: 2000
Journal: Science
Title: Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders.
Volume: 287
Issue: 5456
Pages: 1265-9
•
•
•
•
•
Publication
20071342 | J:161080
First Author: Lee HJ
Year: 2010
Journal: J Biol Chem
Title: Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies.
Volume: 285
Issue: 12
Pages: 9262-72
•
•
•
•
•
Publication
23626796 | J:200633
First Author: Bender A
Year: 2013
Journal: PLoS One
Title: TOM40 mediates mitochondrial dysfunction induced by α-synuclein accumulation in Parkinson's disease.
Volume: 8
Issue: 4
Pages: e62277
•
•
•
•
•
Publication
12009758 | J:76482
First Author: Richfield EK
Year: 2002
Journal: Exp Neurol
Title: Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice.
Volume: 175
Issue: 1
Pages: 35-48
•
•
•
•
•
Publication
38351057 | J:352009
 
First Author: Keomanivong C
Year: 2024
Journal: eNeuro
Title: Mice Expressing A53T/A30P Mutant Alpha-Synuclein in Dopamine Neurons Do Not Display Behavioral Deficits.
Volume: 11
Issue: 2
•
•
•
•
•
Publication
37981650 | J:354471
First Author: McFleder RL
Year: 2023
Journal: Nat Commun
Title: Brain-to-gut trafficking of alpha-synuclein by CD11c(+) cells in a mouse model of Parkinson's disease.
Volume: 14
Issue: 1
Pages: 7529
•
•
•
•
•
Publication
15840579 | J:100267
First Author: Liu CW
Year: 2005
Journal: J Biol Chem
Title: A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease.
Volume: 280
Issue: 24
Pages: 22670-8
•
•
•
•
•
Publication
15684072 | J:96471
First Author: Li W
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations.
Volume: 102
Issue: 6
Pages: 2162-7
•
•
•
•
•
Publication
30249789 | J:267419
First Author: Teravskis PJ
Year: 2018
Journal: J Neurosci
Title: A53T Mutant Alpha-Synuclein Induces Tau-Dependent Postsynaptic Impairment Independently of Neurodegenerative Changes.
Volume: 38
Issue: 45
Pages: 9754-9767
•
•
•
•
•
Publication
15743798 | J:96778
First Author: Stefanova N
Year: 2005
Journal: Am J Pathol
Title: Oxidative stress in transgenic mice with oligodendroglial alpha-synuclein overexpression replicates the characteristic neuropathology of multiple system atrophy.
Volume: 166
Issue: 3
Pages: 869-76
•
•
•
•
•
Publication
30116778 | J:287434
First Author: Sumitomo A
Year: 2018
Journal: Sci Adv
Title: A mouse model of 22q11.2 deletions: Molecular and behavioral signatures of Parkinson's disease and schizophrenia.
Volume: 4
Issue: 8
Pages: eaar6637
•
•
•
•
•
Publication
36167783 | J:353062
First Author: Kulkarni VV
Year: 2022
Journal: J Neurosci
Title: Retrograde Axonal Autophagy and Endocytic Pathways Are Parallel and Separate in Neurons.
Volume: 42
Issue: 45
Pages: 8524-8541
•
•
•
•
•
Publication
19228951 | J:146833
First Author: Lu XH
Year: 2009
Journal: J Neurosci
Title: Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein.
Volume: 29
Issue: 7
Pages: 1962-76
•
•
•
•
•
Publication
31346295 | J:279709
First Author: Henderson MX
Year: 2019
Journal: Nat Neurosci
Title: Spread of α-synuclein pathology through the brain connectome is modulated by selective vulnerability and predicted by network analysis.
Volume: 22
Issue: 8
Pages: 1248-1257
•
•
•
•
•
Publication
31754648 | J:288696
 
First Author: Trubetckaia O
Year: 2019
Journal: Commun Biol
Title: Alpha-synuclein is strategically positioned for afferent modulation of midbrain dopamine neurons and is essential for cocaine preference.
Volume: 2
Pages: 418
•
•
•
•
•
Publication
39426376 | J:358174
     
First Author: Matsuo K
Year: 2024
Journal: Cell
Title: RNA G-quadruplexes form scaffolds that promote neuropathological α-synuclein aggregation.
•
•
•
•
•
Publication
28576704 | J:259157
 
First Author: Abdelmotilib H
Year: 2017
Journal: Neurobiol Dis
Title: α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration.
Volume: 105
Pages: 84-98
•
•
•
•
•
Publication
34233191 | J:328722
First Author: Fonseca-Ornelas L
Year: 2021
Journal: Cell Rep
Title: Altered conformation of α-synuclein drives dysfunction of synaptic vesicles in a synaptosomal model of Parkinson's disease.
Volume: 36
Issue: 1
Pages: 109333
•
•
•
•
•
Publication
30538177 | J:284406
 
First Author: Kim T
Year: 2018
Journal: Sci Signal
Title: The microRNA miR-7a-5p ameliorates ischemic brain damage by repressing α-synuclein.
Volume: 11
Issue: 560
•
•
•
•
•
Publication
30308173 | J:268903
First Author: Nuber S
Year: 2018
Journal: Neuron
Title: Abrogating Native α-Synuclein Tetramers in Mice Causes a L-DOPA-Responsive Motor Syndrome Closely Resembling Parkinson's Disease.
Volume: 100
Issue: 1
Pages: 75-90.e5
•
•
•
•
•
Publication
25009275 | J:353741
First Author: Games D
Year: 2014
Journal: J Neurosci
Title: Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models.
Volume: 34
Issue: 28
Pages: 9441-54
•
•
•
•
•
Publication
25961568 | J:235336
First Author: Schreglmann SR
Year: 2015
Journal: PLoS One
Title: The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice.
Volume: 10
Issue: 5
Pages: e0126261
•
•
•
•
•
Publication
30509990 | J:269264
First Author: Yan R
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB.
Volume: 115
Issue: 51
Pages: E12053-E12062
•
•
•
•
•
Publication
24746855 | J:214012
 
First Author: Savolainen MH
Year: 2014
Journal: Neurobiol Dis
Title: The beneficial effect of a prolyl oligopeptidase inhibitor, KYP-2047, on alpha-synuclein clearance and autophagy in A30P transgenic mouse.
Volume: 68
Pages: 1-15
•
•
•
•
•
Publication
23643841 | J:197984
 
First Author: Hansen C
Year: 2013
Journal: Neurobiol Dis
Title: A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP.
Volume: 56
Pages: 145-55
•
•
•
•
•
Publication
15797547 | J:99814
First Author: Yazawa I
Year: 2005
Journal: Neuron
Title: Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration.
Volume: 45
Issue: 6
Pages: 847-59
•
•
•
•
•
Publication
21966373 | J:177661
First Author: Rieker C
Year: 2011
Journal: PLoS One
Title: Neuropathology in mice expressing mouse alpha-synuclein.
Volume: 6
Issue: 9
Pages: e24834
•
•
•
•
•
Publication
16291942 | J:102867
First Author: Shults CW
Year: 2005
Journal: J Neurosci
Title: Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy.
Volume: 25
Issue: 46
Pages: 10689-99
•
•
•
•
•
Publication
15765523 | J:238692
First Author: Rockenstein E
Year: 2005
Journal: J Neurosci Res
Title: Lysosomal pathology associated with alpha-synuclein accumulation in transgenic models using an eGFP fusion protein.
Volume: 80
Issue: 2
Pages: 247-59
•
•
•
•
•
Publication
32996158 | J:301897
First Author: Nuber S
Year: 2021
Journal: Ann Neurol
Title: A Stearoyl-Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α-Synuclein Mice.
Volume: 89
Issue: 1
Pages: 74-90
•
•
•
•
•
Publication
35179202 | J:351405
First Author: Geertsma HM
Year: 2022
Journal: Hum Mol Genet
Title: Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor impairment and cortical dysfunction, independent of protein aggregation.
Volume: 31
Issue: 21
Pages: 3613-3628
•
•
•
•
•
Publication
10978144 | J:64149
First Author: Rochet JC
Year: 2000
Journal: Biochemistry
Title: Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein.
Volume: 39
Issue: 35
Pages: 10619-26
•
•
•
•
•
Publication
17475220 | J:122473
First Author: Nakai M
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Expression of alpha-synuclein, a presynaptic protein implicated in Parkinson's disease, in erythropoietic lineage.
Volume: 358
Issue: 1
Pages: 104-10
•
•
•
•
•
Publication
20106983 | J:165946
First Author: Doxakis E
Year: 2010
Journal: J Biol Chem
Title: Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153.
Volume: 285
Issue: 17
Pages: 12726-34
•
•
•
•
•
Publication
16959795 | J:154831
First Author: Kontopoulos E
Year: 2006
Journal: Hum Mol Genet
Title: Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity.
Volume: 15
Issue: 20
Pages: 3012-23
•
•
•
•
•
Publication
21563316 | J:212791
First Author: Esposito G
Year: 2012
Journal: Dev Neurobiol
Title: Synaptic vesicle trafficking and Parkinson's disease.
Volume: 72
Issue: 1
Pages: 134-44
•
•
•
•
•
Publication
21127069 | J:168706
First Author: Qureshi HY
Year: 2011
Journal: J Biol Chem
Title: Parkinsonian neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and alpha-synuclein mutations promote Tau protein phosphorylation at Ser262 and destabilize microtubule cytoskeleton in vitro.
Volume: 286
Issue: 7
Pages: 5055-68
•
•
•
•
•
Publication
17222866 | J:212805
First Author: Volles MJ
Year: 2007
Journal: J Mol Biol
Title: Relationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity.
Volume: 366
Issue: 5
Pages: 1510-22
•
•
•
•
•
Publication
11113617 | J:66439
First Author: Sommer B
Year: 2000
Journal: Exp Gerontol
Title: Mouse models of alpha-synucleinopathy and Lewy pathology.
Volume: 35
Issue: 9-10
Pages: 1389-403
•
•
•
•
•
Publication
10786830 | J:61686
First Author: Dawson TM
Year: 2000
Journal: Cell
Title: New animal models for Parkinson's disease.
Volume: 101
Issue: 2
Pages: 115-8
•
•
•
•
•
Publication
10799001 | J:61769
First Author: Dawson VL
Year: 2000
Journal: Science
Title: Neurobiology. Of flies and mice.
Volume: 288
Issue: 5466
Pages: 631-2
•
•
•
•
•
Publication
16242637 | J:102823
First Author: Yavich L
Year: 2005
Journal: Neurobiol Dis
Title: Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human alpha-synuclein.
Volume: 20
Issue: 2
Pages: 303-13
•
•
•
•
•
Publication
15639180 | J:115466
First Author: Siegmund A
Year: 2005
Journal: Behav Brain Res
Title: Differences in extinction of conditioned fear in C57BL/6 substrains are unrelated to expression of alpha-synuclein.
Volume: 157
Issue: 2
Pages: 291-8
•
•
•
•
•
Publication
17108165 | J:116160
First Author: Larsen KE
Year: 2006
Journal: J Neurosci
Title: Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis.
Volume: 26
Issue: 46
Pages: 11915-22
•
•
•
•
•
Publication
18172548 | J:131061
First Author: Martinez-Vicente M
Year: 2008
Journal: J Clin Invest
Title: Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy.
Volume: 118
Issue: 2
Pages: 777-88
•
•
•
•
•
Publication
19286568 | J:147053
First Author: Nakayama K
Year: 2009
Journal: Am J Pathol
Title: Microtubule depolymerization suppresses alpha-synuclein accumulation in a mouse model of multiple system atrophy.
Volume: 174
Issue: 4
Pages: 1471-80
•
•
•
•
•
Publication
18992718 | J:147817
 
First Author: Ikeda M
Year: 2009
Journal: Brain Res
Title: Motor impairment and aberrant production of neurochemicals in human alpha-synuclein A30P+A53T transgenic mice with alpha-synuclein pathology.
Volume: 1250
Pages: 232-41
•
•
•
•
•
Publication
20485674 | J:160921
First Author: Unni VK
Year: 2010
Journal: PLoS One
Title: In vivo imaging of alpha-synuclein in mouse cortex demonstrates stable expression and differential subcellular compartment mobility.
Volume: 5
Issue: 5
Pages: e10589
•
•
•
•
•
Publication
21055449 | J:170285
 
First Author: Kim YH
Year: 2011
Journal: Neuroscience
Title: Inducible dopaminergic glutathione depletion in an α-synuclein transgenic mouse model results in age-related olfactory dysfunction.
Volume: 172
Pages: 379-86
•
•
•
•
•
Publication
20550572 | J:171788
First Author: Feng LR
Year: 2010
Journal: Eur J Neurosci
Title: Alpha-synuclein mediates alterations in membrane conductance: a potential role for alpha-synuclein oligomers in cell vulnerability.
Volume: 32
Issue: 1
Pages: 10-7
•
•
•
•
•
Publication
21982369 | J:178534
First Author: Volpicelli-Daley LA
Year: 2011
Journal: Neuron
Title: Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death.
Volume: 72
Issue: 1
Pages: 57-71
•
•
•
•
•
Publication
21840348 | J:180897
First Author: Park SN
Year: 2011
Journal: Neurosci Res
Title: α-Synuclein deficiency and efferent nerve degeneration in the mouse cochlea: a possible cause of early-onset presbycusis.
Volume: 71
Issue: 3
Pages: 303-10
•
•
•
•
•
Publication
22033456 | J:184032
 
First Author: Huang Z
Year: 2011
Journal: Neuroscience
Title: Determining nuclear localization of alpha-synuclein in mouse brains.
Volume: 199
Pages: 318-32
•
•
•
•
•
Publication
23100443 | J:192170
First Author: Burré J
Year: 2012
Journal: J Neurosci
Title: Systematic mutagenesis of α-synuclein reveals distinct sequence requirements for physiological and pathological activities.
Volume: 32
Issue: 43
Pages: 15227-42
•
•
•
•
•
Publication
24381286 | J:205588
First Author: Guardia-Laguarta C
Year: 2014
Journal: J Neurosci
Title: α-Synuclein is localized to mitochondria-associated ER membranes.
Volume: 34
Issue: 1
Pages: 249-59
•
•
•
•
•
Publication
24058406 | J:206500
First Author: Gardai SJ
Year: 2013
Journal: PLoS One
Title: Elevated alpha-synuclein impairs innate immune cell function and provides a potential peripheral biomarker for Parkinson's disease.
Volume: 8
Issue: 8
Pages: e71634
•
•
•
•
•
Publication
24382629 | J:207504
First Author: Reyes JF
Year: 2014
Journal: Glia
Title: Alpha-synuclein transfers from neurons to oligodendrocytes.
Volume: 62
Issue: 3
Pages: 387-98
•
•
•
•
•
Publication
25471588 | J:218741
First Author: Aelvoet SA
Year: 2014
Journal: J Neurosci
Title: Noninvasive bioluminescence imaging of α-synuclein oligomerization in mouse brain using split firefly luciferase reporters.
Volume: 34
Issue: 49
Pages: 16518-32
•
•
•
•
•
Publication
26076669 | J:223029
 
First Author: Dettmer U
Year: 2015
Journal: Nat Commun
Title: Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation.
Volume: 6
Pages: 7314
•
•
•
•
•
Publication
25428949 | J:228849
 
First Author: Tank J
Year: 2014
Journal: Physiol Rep
Title: Preserved functional autonomic phenotype in adult mice overexpressing moderate levels of human alpha-synuclein in oligodendrocytes.
Volume: 2
Issue: 11
•
•
•
•
•
Publication
30219847 | J:268226
First Author: Pinho R
Year: 2019
Journal: Hum Mol Genet
Title: Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein.
Volume: 28
Issue: 1
Pages: 31-50
•
•
•
•
•
Publication
31358782 | J:283944
First Author: Schaser AJ
Year: 2019
Journal: Sci Rep
Title: Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders.
Volume: 9
Issue: 1
Pages: 10919
•
•
•
•
•
Publication
30796692 | J:295558
First Author: Yan DY
Year: 2019
Journal: Neurotox Res
Title: Mn-Induced Neurocytes Injury and Autophagy Dysfunction in Alpha-Synuclein Wild-Type and Knock-Out Mice: Highlighting the Role of Alpha-Synuclein.
Volume: 36
Issue: 1
Pages: 66-80
•
•
•
•
•
Publication
32817196 | J:302434
 
First Author: Parajuli LK
Year: 2020
Journal: eNeuro
Title: Developmental Changes in Dendritic Spine Morphology in the Striatum and Their Alteration in an A53T α-Synuclein Transgenic Mouse Model of Parkinson's Disease.
Volume: 7
Issue: 4
•
•
•
•
•
Publication
34121985 | J:343007
 
First Author: Li H
Year: 2021
Journal: Front Neurosci
Title: Dl-3-n-Butylphthalide Alleviates Behavioral and Cognitive Symptoms Via Modulating Mitochondrial Dynamics in the A53T-α-Synuclein Mouse Model of Parkinson's Disease.
Volume: 15
Pages: 647266
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom