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to 209 out of 209 for
Soat2
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Type
Details
Score
Publication
First Author:
Chang C
Year:
2006
Journal:
Acta Biochim Biophys Sin (Shanghai)
Title:
Human acyl-CoA:cholesterol acyltransferase (ACAT) and its potential as a target for pharmaceutical intervention against atherosclerosis.
Volume:
38
Issue:
3
Pages:
151-6
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Protein Domain
Type:
Family
Description:
Sterol O-acyltransferase 1 (SOAT1; also known as ACAT1) and sterol O-acyltransferase 2 (SOAT2; also known as ACAT2) both play a role in the formation of fatty acid-cholesterol esters []. Cholesterol esters are less soluble in membranes than cholesterol and accumulate in atherosclerotic lesions, making ACAT inhibitors a pharmacological target against atherosclerosis [, ]. SOAT1 is present in steroidogenic tissues, kidneys, sebaceous glands and macrophages. SOAT2 is expressed predominantly in the liver and small intestine [, ].
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Publication
First Author:
Pramfalk C
Year:
2014
Journal:
J Lipid Res
Title:
TG-interacting factor 1 acts as a transcriptional repressor of sterol O-acyltransferase 2.
Volume:
55
Issue:
4
Pages:
709-17
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Publication
First Author:
Devlin AM
Year:
2010
Journal:
J Nutr
Title:
Hepatic acyl-coenzyme a:cholesterol acyltransferase-2 expression is decreased in mice with hyperhomocysteinemia.
Volume:
140
Issue:
2
Pages:
231-7
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Protein
Organism:
Mus musculus/domesticus
Length:
525
Fragment?:
false
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Protein
Organism:
Mus musculus/domesticus
Length:
540
Fragment?:
false
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Protein
Organism:
Mus musculus/domesticus
Length:
462
Fragment?:
true
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Protein
Organism:
Mus musculus/domesticus
Length:
540
Fragment?:
false
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Publication
First Author:
Wang R
Year:
2013
Journal:
Gene
Title:
Differential expression of genes and changes in glucose metabolism in the liver of liver-specific glucokinase gene knockout mice.
Volume:
516
Issue:
2
Pages:
248-54
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