|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 300 out of 309 for Sorcs2

<< First    < Previous  |  Next >    Last >>
0.041s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:2677005
Assay Type: RNA in situ
Annotation Date: 2003-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:2677010
Age: embryonic day 16.5
Image: 2C
Specimen Label: 2C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6189572
Assay Type: RNA in situ
Annotation Date: 2018-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6189602
Age: postnatal day 3
Image: 5I
Specimen Label: 5I
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6189572
Assay Type: RNA in situ
Annotation Date: 2018-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6189602
Age: postnatal day 3
Specimen Label: Table 2 P3
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6189572
Assay Type: RNA in situ
Annotation Date: 2018-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189602
Age: postnatal day 7
Specimen Label: Table 2 P7
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6189572
Assay Type: RNA in situ
Annotation Date: 2018-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189602
Age: postnatal adult
Specimen Label: Table 2 adult
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6189572
Assay Type: RNA in situ
Annotation Date: 2018-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3566727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6189602
Age: postnatal day 3
Image: 5C
Specimen Label: 5C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6189572
Assay Type: RNA in situ
Annotation Date: 2018-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3566728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189602
Age: postnatal day 7
Image: 6C
Specimen Label: 6C
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6189572
Assay Type: RNA in situ
Annotation Date: 2018-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3566727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6189602
Age: postnatal day 3
Specimen Label: Table 2 P3
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6189572
Assay Type: RNA in situ
Annotation Date: 2018-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3566728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189602
Age: postnatal day 7
Specimen Label: Table 2 P7
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6189572
Assay Type: RNA in situ
Annotation Date: 2018-07-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3591026
Stage: TS26
Assay Id: MGI:6189602
Age: embryonic day 18.0
Image: 4F
Specimen Label: 4F
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4424909
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828381
Age: embryonic day 14.5
Image: euxassay_014493_07
Specimen Label: euxassay_014493_07
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4424909
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828381
Age: embryonic day 14.5
Image: euxassay_014493_08
Specimen Label: euxassay_014493_08
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4424909
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828381
Age: embryonic day 14.5
Image: euxassay_014493_09
Specimen Label: euxassay_014493_09
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4424909
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828381
Age: embryonic day 14.5
Image: euxassay_014493_10
Specimen Label: euxassay_014493_10
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4424909
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828381
Age: embryonic day 14.5
Image: euxassay_014493_13
Specimen Label: euxassay_014493_13
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4424909
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828381
Age: embryonic day 14.5
Image: euxassay_014493_14
Specimen Label: euxassay_014493_14
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4424909
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828381
Age: embryonic day 14.5
Image: euxassay_014493_15
Specimen Label: euxassay_014493_15
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:2677005
Assay Type: RNA in situ
Annotation Date: 2003-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3273024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:2677010
Age: embryonic day 16.5
Image: 2C
Specimen Label: 2C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:2677005
Assay Type: RNA in situ
Annotation Date: 2003-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3273022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:2677010
Age: embryonic day 14.5
Image: 2B
Specimen Label: 2B
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:2677005
Assay Type: RNA in situ
Annotation Date: 2003-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:2677010
Age: embryonic day 14.5
Image: 2G
Note: Expression is in the ventral spinal cord extending dorsally.
Specimen Label: 2G
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:2677005
Assay Type: RNA in situ
Annotation Date: 2003-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:2677010
Age: embryonic day 16.5
Image: 2M
Note: Strong signals over the ependymal layer and weak signals over the substantia nigra.
Specimen Label: 2M
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:2677005
Assay Type: RNA in situ
Annotation Date: 2003-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:2677010
Age: postnatal adult
Note: The authors state that this gene was differentially expressed in the adult brain, but did not provide details.
Specimen Label: Not Shown
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6189572
Assay Type: RNA in situ
Annotation Date: 2018-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6189602
Age: embryonic day 12.0
Image: 3C
Note: Expression is in the medial and posterior neuroepithelium.
Specimen Label: 3C
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:2677005
Assay Type: RNA in situ
Annotation Date: 2003-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:2677010
Age: embryonic day 16.5
Image: 3A
Note: Expression is in facial mesenchyme.
Specimen Label: 3A
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:2677005
Assay Type: RNA in situ
Annotation Date: 2003-10-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1726019
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:2677010
Age: embryonic day 11.5
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:2677005
Assay Type: RNA in situ
Annotation Date: 2003-10-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1726019
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:2677010
Age: embryonic day 11.5
Image: 2H
Specimen Label: 2H
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6189572
Assay Type: RNA in situ
Annotation Date: 2018-07-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3591126
Stage: TS26
Assay Id: MGI:6189602
Age: embryonic day 18.0
Image: 4F
Specimen Label: 4F
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3585083
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3585920
Age: embryonic day 14.0
Note: Expression was detected in a subset of cells in the outer neuroblastic layer.
Specimen Label: E14
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6189572
Assay Type: RNA in situ
Annotation Date: 2018-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3673128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189602
Age: postnatal adult
Specimen Label: Table 2 adult
Detected: true
Specimen Num: 17
•
•
•
•
•
Publication
24715575 | J:217851
First Author: Oetjen S
Year: 2014
Journal: J Comp Neurol
Title: Spatiotemporal expression analysis of the growth factor receptor SorCS3.
Volume: 522
Issue: 15
Pages: 3386-402
•
•
•
•
•
Publication
34611268 | J:312837
First Author: Vignoli B
Year: 2021
Journal: Commun Biol
Title: Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention.
Volume: 4
Issue: 1
Pages: 1152
•
•
•
•
•
Publication
23091165 | J:190893
First Author: Siao CJ
Year: 2012
Journal: J Exp Med
Title: ProNGF, a cytokine induced after myocardial infarction in humans, targets pericytes to promote microvascular damage and activation.
Volume: 209
Issue: 12
Pages: 2291-305
•
•
•
•
•
Publication
14645517 | J:86868
First Author: Simon R
Year: 2003
Journal: Mol Cell Biol
Title: Postnatal lethality in mice lacking the Sax2 homeobox gene homologous to Drosophila S59/slouch: evidence for positive and negative autoregulation.
Volume: 23
Issue: 24
Pages: 9046-60
•
•
•
•
•
Publication
12465718 | J:86755
First Author: Okazaki N
Year: 2002
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 9
Issue: 5
Pages: 179-88
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
•
•
•
•
•
Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
•
•
•
•
•
Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
•
•
•
•
•
Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
•
•
•
•
•
Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
•
•
•
•
Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
•
•
•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Component
Component
Name: SorCS2 122 kDa chain
•
•
•
•
•
Component
Component
Name: SorCS2 104 kDa chain
•
•
•
•
•
Component
Component
Name: SorCS2 18 kDa chain
•
•
•
•
•
UniProt Feature
UniProt Feature
 
Description: SorCS2 122 kDa chain
Type: chain
End: 1159
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 50
Description: VPS10 domain-containing receptor SorCS2
Type: chain
End: 1159
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 118
Description: SorCS2 104 kDa chain
Type: chain
End: 1030
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 1031
Description: SorCS2 18 kDa chain
Type: chain
End: 1159
•
•
•
•
•
Protein
Q9EPR5
Organism: Mus musculus/domesticus
Length: 1159  
Fragment?: false
•
•
•
•
•
Protein
D3YYF4
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
•
•
•
•
•
Protein
Q8BI74
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: false
•
•
•
•
•
Interaction Experiment
Glerup S (2016)
Description: SorCS2 is required for BDNF-dependent plasticity in the hippocampus.
•
•
•
•
•
Publication
30061605 | -
First Author: Leloup N
Year: 2018
Journal: Nat Commun
Title: Structural insights into SorCS2-Nerve Growth Factor complex formation.
Volume: 9
Issue: 1
Pages: 2979
•
•
•
•
•
Publication
22155786 | J:260288
First Author: Deinhardt K
Year: 2011
Journal: Sci Signal
Title: Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac.
Volume: 4
Issue: 202
Pages: ra82
•
•
•
•
•
Publication
29909994 | J:267910
First Author: Giza JI
Year: 2018
Journal: Neuron
Title: The BDNF Val66Met Prodomain Disassembles Dendritic Spines Altering Fear Extinction Circuitry and Behavior.
Volume: 99
Issue: 1
Pages: 163-178.e6
•
•
•
•
•
Publication
11499680 | -
First Author: Hampe W
Year: 2001
Journal: Hum Genet
Title: The genes for the human VPS10 domain-containing receptors are large and contain many small exons.
Volume: 108
Issue: 6
Pages: 529-36
•
•
•
•
•
Protein Domain
IPR022409 | PKD/Chitinase_dom
Type: Domain
Description: The PKD (Polycystic Kidney Disease) domain was first identified in the Polycystic Kidney Disease protein, polycystin-1 (PDK1 gene), and contains an Ig-like fold consisting of a β-sandwich of seven strands in two sheets with a Greek key topology, although some members have additional strands []. Polycystin-1 is a large cell-surface glycoprotein involved in adhesive protein-protein and protein-carbohydrate interactions; however it is not clear if the PKD domain mediates any of these interactions. PKD domains are also found in other proteins, usually in the extracellular parts of proteins involved in interactions with other proteins. For example, domains with a PKD-type fold are found in archaeal surface layer proteins that protect the cell from extreme environments [], and in the human VPS10 domain-containing receptor SorCS2 [].
•
•
•
•
•
Publication
12377130 | -
First Author: Jing H
Year: 2002
Journal: Structure
Title: Archaeal surface layer proteins contain beta propeller, PKD, and beta helix domains and are related to metazoan cell surface proteins.
Volume: 10
Issue: 10
Pages: 1453-64
•
•
•
•
•
Publication
19656770 | -
First Author: Gundry RL
Year: 2009
Journal: Mol Cell Proteomics
Title: The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.
Volume: 8
Issue: 11
Pages: 2555-69
•
•
•
•
•
Protein
Q99P91
Organism: Mus musculus/domesticus
Length: 574  
Fragment?: false
•
•
•
•
•
Protein
Q8K135
Organism: Mus musculus/domesticus
Length: 1048  
Fragment?: false
•
•
•
•
•
Protein
Q5SZV5
Organism: Mus musculus/domesticus
Length: 1081  
Fragment?: false
•
•
•
•
•
Protein
Q60696
Organism: Mus musculus/domesticus
Length: 626  
Fragment?: false
•
•
•
•
•
Protein
Q5DU58
Organism: Mus musculus/domesticus
Length: 838  
Fragment?: true
•
•
•
•
•
Protein
Q3TWC7
Organism: Mus musculus/domesticus
Length: 574  
Fragment?: false
•
•
•
•
•
Protein
Q9CZB2
Organism: Mus musculus/domesticus
Length: 626  
Fragment?: false
•
•
•
•
•
Protein
Q8BVA0
Organism: Mus musculus/domesticus
Length: 526  
Fragment?: false
•
•
•
•
•
Protein
Q3TAV1
Organism: Mus musculus/domesticus
Length: 574  
Fragment?: false
•
•
•
•
•
Protein
Q3TBB0
Organism: Mus musculus/domesticus
Length: 574  
Fragment?: false
•
•
•
•
•
Protein
F2Z497
Organism: Mus musculus/domesticus
Length: 782  
Fragment?: false
•
•
•
•
•
Protein
Q3UFC3
Organism: Mus musculus/domesticus
Length: 985  
Fragment?: true
•
•
•
•
•
Protein
Z4YK56
Organism: Mus musculus/domesticus
Length: 1085  
Fragment?: false
•
•
•
•
•
Protein
Q3TXG7
Organism: Mus musculus/domesticus
Length: 574  
Fragment?: false
•
•
•
•
•
Publication
9889186 | -
First Author: Bycroft M
Year: 1999
Journal: EMBO J
Title: The structure of a PKD domain from polycystin-1: implications for polycystic kidney disease.
Volume: 18
Issue: 2
Pages: 297-305
•
•
•
•
•
Protein
Q8R526
Organism: Mus musculus/domesticus
Length: 2615  
Fragment?: false
•
•
•
•
•
Protein
A0A0A0MQK4
Organism: Mus musculus/domesticus
Length: 2521  
Fragment?: true
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom