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Search results 201 to 300 out of 309 for Sp4

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:5792138
Assay Type: RNA in situ
Annotation Date: 2016-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5792140
Age: embryonic day 12.0
Image: 5E
Specimen Label: 5E
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:5792138
Assay Type: RNA in situ
Annotation Date: 2016-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:5792140
Age: embryonic day 16.0
Specimen Label: E16 not shown
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
Probe: MGI:5792138
Assay Type: RNA in situ
Annotation Date: 2016-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1609816
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:5792140
Age: embryonic day 10.0
Image: 4B
Note: Weaker expression in cephalic mesenchymal tissue adjacent to the brain and neural tube.
Specimen Label: 4B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5792138
Assay Type: RNA in situ
Annotation Date: 2016-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1609816
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:5792140
Age: embryonic day 10.0
Image: 4C
Note: Low level of expression in much of the primitive mesenchymal tissue in the head region, including the branchial arches.
Specimen Label: 4C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5792138
Assay Type: RNA in situ
Annotation Date: 2016-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1609820
Pattern: Diffuse
Stage: TS20
Assay Id: MGI:5792140
Age: embryonic day 12.0
Image: 5A
Note: Weak, diffuse expression throughout facial mesenchymal tissue surrounding the nasopharyngeal cavity.
Specimen Label: 5A
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5792138
Assay Type: RNA in situ
Annotation Date: 2016-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1609820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5792140
Age: embryonic day 12.0
Image: 5B
Note: Weak, diffuse expression in facial mesenchyme.
Specimen Label: 5B
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:5792138
Assay Type: RNA in situ
Annotation Date: 2016-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1609820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5792140
Age: embryonic day 12.0
Note: Weak expression throughout most mesenchymal tissue in the head and neck region, limbs, and abdominal cavity.
Specimen Label: E12 not shown
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:5792138
Assay Type: RNA in situ
Annotation Date: 2016-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1796221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5792140
Age: embryonic day 13.0
Specimen Label: E13 not shown
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:5792138
Assay Type: RNA in situ
Annotation Date: 2016-09-14
Strength: Weak
Sex: Male
Emaps: EMAPS:1689321
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5792140
Age: embryonic day 13.0
Image: 6A
Note: Low level of expression in mesenchymal tissue in the abdominal wall.
Specimen Label: 6A
Detected: true
Specimen Num: 9
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Publication
16430881 | J:107057
First Author: St Amand TR
Year: 2006
Journal: Dev Biol
Title: Distinct roles of HF-1b/Sp4 in ventricular and neural crest cells lineages affect cardiac conduction system development.
Volume: 291
Issue: 2
Pages: 208-17
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Publication
27889927 | J:238550
First Author: Wegener A
Year: 2017
Journal: J Neurochem
Title: Sp2 is the only glutamine-rich specificity protein with minor impact on development and differentiation in myelinating glia.
Volume: 140
Issue: 2
Pages: 245-256
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Publication
14988733 | J:88876
First Author: Dreveny I
Year: 2004
Journal: EMBO J
Title: Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47.
Volume: 23
Issue: 5
Pages: 1030-9
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Publication
11007485 | J:77375
First Author: Nguyên-Trân VT
Year: 2000
Journal: Cell
Title: A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages.
Volume: 102
Issue: 5
Pages: 671-82
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Publication
36577384 | J:332407
First Author: Gu Y
Year: 2022
Journal: Cell Rep
Title: Multi-omics profiling visualizes dynamics of cardiac development and functions.
Volume: 41
Issue: 13
Pages: 111891
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Publication
15820306 | J:97532
First Author: Suske G
Year: 2005
Journal: Genomics
Title: Mammalian SP/KLF transcription factors: bring in the family.
Volume: 85
Issue: 5
Pages: 551-6
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Publication
22174793 | J:182258
First Author: Taher L
Year: 2011
Journal: PLoS One
Title: Global gene expression analysis of murine limb development.
Volume: 6
Issue: 12
Pages: e28358
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: Transcription factor Sp4
Type: chain
End: 782
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Gene
108719922 | sp4.S
Type: gene
Organism: frog, African clawed
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Gene
398919 | sp4.L
Type: gene
Organism: frog, African clawed
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Strain
MGI:4834479 | B6.129P2-Sp4<tm1Sus>/Cnrm
Attribute String: mutant strain, targeted mutation, congenic
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Publication
7607696 | J:25711
First Author: Kalff-Suske M
Year: 1995
Journal: Genomics
Title: Human Sp4 transcription factor gene (SP4) maps to chromosome 7p15.
Volume: 26
Issue: 3
Pages: 631-3
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Protein
Q9JMJ7
Organism: Mus musculus/domesticus
Length: 39  
Fragment?: true
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7579184
Age: embryonic day 18.5
Note: Co-localization of expression with Sp4 in cortex.
Specimen Label: 9 P450scc Whiskers
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7579184
Age: embryonic day 9.5
Note: Expression co-localized with Sp4 in Rathke's pouch.
Specimen Label: 7 P450scc (lower)
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607315
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7579184
Age: embryonic day 9.5
Note: Expression co-localized with Sp4 in ventral neurectoderm.
Specimen Label: 7 P450scc (lower)
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611715
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7579184
Age: embryonic day 9.5
Note: Expression co-localized with Sp4 in branchial arches.
Specimen Label: 7 P450scc (lower)
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579184
Age: embryonic day 18.5
Note: Co-localization of expression with Sp1 and Sp4 in cortical plate.
Specimen Label: 8 P450scc Cortex
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:7579181
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579189
Age: embryonic day 18.5
Note: Co-localization of expression with Cyp11a1 and Sp4 in cortical plate.
Specimen Label: 8 Sp1 Cortex
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579184
Age: embryonic day 18.5
Note: Co-localization of expression with Sp1 and Sp4 in hippocampal neuroepithelium.
Specimen Label: 8 P450scc Hippocampus
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:7579181
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579189
Age: embryonic day 18.5
Note: Co-localization of expression with Cyp11a1 and Sp4 in hippocampal neuroeipithelium.
Specimen Label: 8 Sp1 Hippocampus
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579184
Age: embryonic day 18.5
Note: Co-localization of expression with Sp1 and Sp4 in trigeminal ganglia.
Specimen Label: 9 P450scc Trigeminal Ganglion (upper)
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579184
Age: embryonic day 18.5
Note: Co-localization of expression with Sp1 and Sp4 in neurons.
Specimen Label: 9 P450scc Trigeminal Ganglion (lower)
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
 
Probe: MGI:7579181
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579189
Age: embryonic day 18.5
Note: Co-localization of expression with Cyp11a1 and Sp4 in trigeminal ganglia
Specimen Label: 9 Sp1 Trigeminal Ganglion (upper)
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:7579181
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579189
Age: embryonic day 18.5
Note: Co-localization of expression with Cyp11a1 and Sp4 in neurons.
Specimen Label: 9 Sp1 Trigeminal Ganglion (lower)
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3599826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579184
Age: embryonic day 18.5
Note: Co-localization of expression with Sp1 and Sp4 in pituitary primordium.
Specimen Label: 8 P450scc Pituitary
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
 
Probe: MGI:7579181
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3599826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579189
Age: embryonic day 18.5
Note: Co-localization of expression with Cyp11a1 and Sp4 in pituitary primordium.
Specimen Label: 8 Sp1 Pituitary
Detected: true
Specimen Num: 5
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Publication
7559627 | -
First Author: Hagen G
Year: 1995
Journal: J Biol Chem
Title: Functional analyses of the transcription factor Sp4 reveal properties distinct from Sp1 and Sp3.
Volume: 270
Issue: 42
Pages: 24989-94
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579184
Age: embryonic day 18.5
Note: Co-localization of expression with Sp1 and Sp4 in amacrine cells of retina.
Specimen Label: 8 P450scc Retina
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:7579181
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579189
Age: embryonic day 18.5
Note: Co-localization of expression with Cyp11a1 and Sp4 in amacrine cells of retina.
Specimen Label: 8 Sp1 Retina
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579184
Age: embryonic day 18.5
Note: Co-localization of expression with Sp1 and Sp4 in ganglion cell layer and inner nuclear layer.
Specimen Label: 8 P450scc Retina
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:7579181
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579189
Age: embryonic day 18.5
Note: Co-localization of expression with Cyp11a1 and Sp4 in ganglion cell layer and inner nuclear layer
Specimen Label: 8 Sp1 Retina
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7579181
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7579189
Age: embryonic day 18.5
Note: Co-localization of expression with Cyp11a1 and Sp4 in molecular layer of neocortex.
Specimen Label: 8 Sp1 Cortex
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579184
Age: embryonic day 18.5
Note: Co-localization of expression with Sp1 and Sp4 in dorsal root ganglia.
Specimen Label: 9 P450scc Dorsal Root Ganglion
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:7579181
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579189
Age: embryonic day 18.5
Note: Co-localization of expression with Cyp11a1 and Sp4 in dorsal root ganglia.
Specimen Label: 9 Sp1 Dorsal Root Ganglion
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579184
Age: embryonic day 18.5
Note: Co-localization of expression with Sp1 and Sp4 in Purkinje cell layer of cerebellum.
Specimen Label: 8 P450scc Cerebellum
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:7579181
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579189
Age: embryonic day 18.5
Note: Co-localization of expression with Cyp11a1 and Sp4 in Purkinje cell layer of cerebellum.
Specimen Label: 8 Sp1 Cerebellum
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573926
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579184
Age: embryonic day 18.5
Note: Co-localization of expression with Sp1 and Sp4 in ganglion cell layer and inner nuclear layer.
Specimen Label: 8 P450scc Retina
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:7579181
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573926
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579189
Age: embryonic day 18.5
Note: Co-localization of expression with Cyp11a1 and Sp4 in ganglion cell layer and inner nuclear layer
Specimen Label: 8 Sp1 Retina
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642217
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7579184
Age: embryonic day 10.5
Note: Expression co-localized with Sp4 in cells that appear to be in position of cells migrating from neural crest.
Specimen Label: P450scc E10.5 not shown
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:7579178
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7579184
Age: embryonic day 18.5
Note: Co-localization of expression with Sp1 and Sp4 in molecular layer of neocortex. Expression appears to be glial.
Specimen Label: 8 P450scc Cortex
Detected: true
Specimen Num: 13
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Allele
lgl | MGI:1856934
 
Name: legless
Allele Type: Transgenic
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Publication
3406741 | J:9298
First Author: McNeish JD
Year: 1988
Journal: Science
Title: Legless, a novel mutation found in PHT1-1 transgenic mice.
Volume: 241
Issue: 4867
Pages: 837-9
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Publication
9651475 | J:49210
First Author: Bell SM
Year: 1998
Journal: Mech Dev
Title: The loss of ventral ectoderm identity correlates with the inability to form an AER in the legless hindlimb bud.
Volume: 74
Issue: 1-2
Pages: 41-50
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Publication
8026630 | J:19197
First Author: Scott WJ
Year: 1994
Journal: Dev Biol
Title: Enhanced expression of limb malformations and axial skeleton alterations in legless mutants by transplacental exposure to retinoic acid.
Volume: 164
Issue: 1
Pages: 277-89
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Publication
2313245 | J:19362
First Author: McNeish JD
Year: 1990
Journal: J Exp Zool
Title: Phenotypic characterization of the transgenic mouse insertional mutation, legless.
Volume: 253
Issue: 2
Pages: 151-62
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Publication
8115388 | J:18438
 
First Author: Scott WJ
Year: 1993
Journal: Prog Clin Biol Res
Title: Exacerbation of limb malformations in legless (lgl) homozygotes by retinoic acid (RA).
Volume: 383B
Pages: 735-8
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Publication
1748282 | J:1861
First Author: Singh G
Year: 1991
Journal: Genes Dev
Title: legless insertional mutation: morphological, molecular, and genetic characterization.
Volume: 5
Issue: 12A
Pages: 2245-55
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Publication
8344471 | J:13167
First Author: Schreiner CM
Year: 1993
Journal: Dev Biol
Title: Correlation of forelimb malformation asymmetries with visceral organ situs in the transgenic mouse insertional mutation, legless.
Volume: 158
Issue: 2
Pages: 560-2
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Genotype
Genotype
Symbol: lgl/lgl
Background: involves: C3H * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: lgl/lgl<+>
Background: involves: C3H * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Publication
9353118 | J:44093
First Author: Supp DM
Year: 1997
Journal: Nature
Title: Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice.
Volume: 389
Issue: 6654
Pages: 963-6
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•
•
•
Publication
9438343 | J:45219
First Author: Meyer RA
Year: 1997
Journal: Dev Genet
Title: Developmental regulation and asymmetric expression of the gene encoding Cx43 gap junctions in the mouse limb bud.
Volume: 21
Issue: 4
Pages: 290-300
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Genotype
Genotype
Symbol: lgl/lgl<+> Sp8/Sp8<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
14526104 | J:86196
First Author: Bell SM
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Sp8 is crucial for limb outgrowth and neuropore closure.
Volume: 100
Issue: 21
Pages: 12195-200
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Allele
Sp4<tm3(Sp4)Krc> | MGI:3663671
Name: trans-acting transcription factor 4; targeted mutation 3, Kenneth R Chien
Allele Type: Targeted
Attribute String: Conditional ready, Hypomorph, Reporter
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Publication
29361554 | J:257929
 
First Author: Solanki A
Year: 2018
Journal: Development
Title: Gli3 in fetal thymic epithelial cells promotes thymocyte positive selection and differentiation by repression of Shh.
Volume: 145
Issue: 3
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Publication
9920775 | J:53658
First Author: Yamaguchi H
Year: 1999
Journal: Biochem Biophys Res Commun
Title: A PEA3 site flanked by SP1, SP4, and GATA sites positively regulates the differentiation-dependent expression of Brachyury in embryonal carcinoma P19 cells.
Volume: 254
Issue: 3
Pages: 542-7
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Strain
MGI:5911812 | 129/Sv-Sp4<tm3(Sp4)Krc>/Mmnc
Attribute String: mutant stock, targeted mutation
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Genotype
Genotype
Symbol: Sp4/Sp4
Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss
Zygosity: hm
Has Mutant Allele: true
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•
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