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Search results 201 to 210 out of 210 for Spc25

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Type Details Score
Protein
Organism: Mus musculus/domesticus
Length: 226  
Fragment?: false
Publication
First Author: Wei RR
Year: 2006
Journal: Structure
Title: Structure of a central component of the yeast kinetochore: the Spc24p/Spc25p globular domain.
Volume: 14
Issue: 6
Pages: 1003-9
Protein Domain
Type: Homologous_superfamily
Description: Spc24 is a component of the evolutionarily conserved kinetochore-associated Ndc80 complex, which is implicated in several essential outer kinetochore functions, including microtubule binding and control the spindle assembly checkpoint [, ].The Ndc80 complex appears to be a long rod with globular 'heads'. Ndc80 and Nuf2 contribute to one head and to the intervening shaft; Spc24 and Spc25 complete the shaft and contribute to the other head. Spc24 and Spc25 fold tightly together. TheC-terminal globular domains of Spc24 and Spc25 form the 'inner' head, which faces the centromere [].
Protein Domain
Type: Domain
Description: The Ndc80 complex is a conserved outer kinetochore protein complex consisting of Ndc80 (Hec1), Nuf2, Spc24 and Spc25. The Ndc80 complex is required for chromosome segregation and spindle checkpoint activity [, , ].This entry represents the C-terminal domain of Spc25 [].
Publication
First Author: Kalies KU
Year: 1996
Journal: J Biol Chem
Title: Membrane topology of the 12- and the 25-kDa subunits of the mammalian signal peptidase complex.
Volume: 271
Issue: 7
Pages: 3925-9
Publication
First Author: Kim S
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Structure of human Mad1 C-terminal domain reveals its involvement in kinetochore targeting.
Volume: 109
Issue: 17
Pages: 6549-54
Publication
First Author: Pathania R
Year: 2016
Journal: Cancer Res
Title: Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth.
Volume: 76
Issue: 11
Pages: 3224-35
Publication      
First Author: Keller MP
Year: 2023
Journal: Diabetes
Title: An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets.
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112