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Search results 201 to 228 out of 228 for Spns2

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Type Details Score
lncRNA Gene
MGI_C57BL6J_5623079 | -
Type: lncRNA_gene
Organism: mouse, laboratory
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Protein
Q91VM4
Organism: Mus musculus/domesticus
Length: 549  
Fragment?: false
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Protein
Q91VM4-2
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: false
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Allele
Spns2<em1Smoc> | MGI:7292569
Name: SPNS lysolipid transporter 2, sphingosine-1-phosphate; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6355222 | C57BL/6JSmoc-Spns2<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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DO Term
DOID:0111643 | autosomal recessive nonsyndromic deafness 115
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Protein
F6WK70
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: true
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Protein
Q3TN98
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Publication
21562262 | -
First Author: Yuva-Aydemir Y
Year: 2011
Journal: J Neurosci
Title: Spinster controls Dpp signaling during glial migration in the Drosophila eye.
Volume: 31
Issue: 19
Pages: 7005-15
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Publication
26966342 | -
 
First Author: Aoki M
Year: 2016
Journal: Mediators Inflamm
Title: Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential.
Volume: 2016
Pages: 8606878
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Protein Domain
IPR044770 | MFS_spinster-like
Type: Family
Description: The entry includes Drosophila protein spinster [], its vertebrate homologues, and the MFS-type efflux pumps from bacteria. Humans contain three homologues called protein spinster homologues 1 (SPNS1), 2 (SPNS2), and 3 (SPNS3). Protein spinster and its homologues may be sphingolipid transporters that play central roles in endosomes and/or lysosomes storage. SPNS2 is also called sphingosine 1-phosphate (S1P) transporter and is required for migration of myocardial precursors. S1P is a secreted lipid mediator that plays critical roles in cardiovascular, immunological, and neural development and function [, , ]. These proteins belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Also included in this family are the probable sphingolipid transporter spinster homologues 1-3 from Arabidopsis thaliana.
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Publication
25333900 | J:222451
 
First Author: Keller J
Year: 2014
Journal: Nat Commun
Title: Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts.
Volume: 5
Pages: 5215
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Publication
27343196 | J:236415
First Author: Harijith A
Year: 2016
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium.
Volume: 311
Issue: 2
Pages: L337-51
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Publication
28351953 | J:259347
 
First Author: Andrieu G
Year: 2017
Journal: Sci Signal
Title: Sphingosine 1-phosphate signaling through its receptor S1P5 promotes chromosome segregation and mitotic progression.
Volume: 10
Issue: 472
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Publication
38451736 | J:346909
 
First Author: Ha HT
Year: 2024
Journal: JCI Insight
Title: Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models.
Volume: 9
Issue: 8
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Publication
30279138 | J:270464
First Author: Pierucci F
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Involvement of released sphingosine 1-phosphate/sphingosine 1-phosphate receptor axis in skeletal muscle atrophy.
Volume: 1864
Issue: 12
Pages: 3598-3614
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Publication
35976996 | J:330059
First Author: Tanaka S
Year: 2022
Journal: Sci Transl Med
Title: Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney.
Volume: 14
Issue: 658
Pages: eabj2681
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Protein
Q8R0G7
Organism: Mus musculus/domesticus
Length: 528  
Fragment?: false
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Protein
Q9D232
Organism: Mus musculus/domesticus
Length: 514  
Fragment?: false
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Protein
D3YWA9
Organism: Mus musculus/domesticus
Length: 453  
Fragment?: false
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Protein
D3YWU4
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: true
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Protein
Q3U1F5
Organism: Mus musculus/domesticus
Length: 472  
Fragment?: true
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Protein
D3YTR6
Organism: Mus musculus/domesticus
Length: 476  
Fragment?: false
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Protein
A0A0U1RPY3
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: true
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Protein
D6REG2
Organism: Mus musculus/domesticus
Length: 165  
Fragment?: false
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Protein
A0A0U1RNZ2
Organism: Mus musculus/domesticus
Length: 167  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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