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Search results 201 to 254 out of 254 for Srgap1

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Type

Details

Score

GXD Expression

Probe:	MGI:7619948
Assay Type:	RNA in situ
Annotation Date:	2024-04-17
Strength:	Strong
Sex:	Not Specified
Emaps:	EMAPS:3561127
Pattern:	Not Specified
Stage:	TS27
Assay Id:	MGI:7621438
Age:	postnatal day 1
Image:	5D

Specimen Label:	5D
Detected:	true
Specimen Num:	17

•

GXD Expression

Probe:	MGI:7619948
Assay Type:	RNA in situ
Annotation Date:	2024-04-17
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3561122
Pattern:	Not Specified
Stage:	TS22
Assay Id:	MGI:7621438
Age:	embryonic day 14.5


Specimen Label:	Table 1 E14.5
Detected:	true
Specimen Num:	23

•

GXD Expression

Probe:	MGI:7619948
Assay Type:	RNA in situ
Annotation Date:	2024-04-17
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3561124
Pattern:	Not Specified
Stage:	TS24
Assay Id:	MGI:7621438
Age:	embryonic day 16.5


Specimen Label:	Table 1 E16.5
Detected:	true
Specimen Num:	24

•

GXD Expression

Probe:	MGI:7619948
Assay Type:	RNA in situ
Annotation Date:	2024-04-17
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3561127
Pattern:	Not Specified
Stage:	TS27
Assay Id:	MGI:7621438
Age:	postnatal day 1


Specimen Label:	Table 1 P1
Detected:	true
Specimen Num:	25

•

GXD Expression

Probe:	MGI:7619948
Assay Type:	RNA in situ
Annotation Date:	2024-04-17
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3791722
Pattern:	Scattered
Stage:	TS22
Assay Id:	MGI:7621438
Age:	embryonic day 14.5
Image:	5A
Note:	Expression is in some scattered neurons of the ganglion layer.
Specimen Label:	5A
Detected:	true
Specimen Num:	16

•

GXD Expression

Probe:	MGI:7619948
Assay Type:	RNA in situ
Annotation Date:	2024-04-17
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3791721
Pattern:	Regionally restricted
Stage:	TS21
Assay Id:	MGI:7621438
Age:	embryonic day 13.5

Note:	Expression is in the mitral layer and is absent in the granule cell layer.
Specimen Label:	Table 1 E13.5
Detected:	true
Specimen Num:	22

•

GXD Expression

Probe:	MGI:7619948
Assay Type:	RNA in situ
Annotation Date:	2024-04-17
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3791722
Pattern:	Regionally restricted
Stage:	TS22
Assay Id:	MGI:7621438
Age:	embryonic day 14.5

Note:	Expression is in the granule cell layer.
Specimen Label:	Table 1 E14.5
Detected:	true
Specimen Num:	23

•

GXD Expression

Probe:	MGI:7619948
Assay Type:	RNA in situ
Annotation Date:	2024-04-17
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3826128
Pattern:	Not Specified
Stage:	TS28
Assay Id:	MGI:7621438
Age:	postnatal day 7


Specimen Label:	Table 1 P7
Detected:	true
Specimen Num:	26

•

Publication

21655271 | J:223910

First Author:	Bacon C
Year:	2011
Journal:	PLoS One
Title:	Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.
Volume:	6
Issue:	5
Pages:	e19887

•

Publication

21931791 | J:177885

First Author:	Brunskill EW
Year:	2011
Journal:	PLoS One
Title:	Defining the molecular character of the developing and adult kidney podocyte.
Volume:	6
Issue:	9
Pages:	e24640

•

Publication

- | J:66660

First Author:	Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year:	2001

Title:	LocusLink Collaboration

•

Publication

- | J:68100

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2001

Title:	RIKEN Data Curation in Mouse Genome Informatics

•

Publication

- | J:84900

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2003
Journal:	Database Download
Title:	Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database

•

Publication

- | J:204812

First Author:	International Mouse Strain Resource
Year:	2014
Journal:	Database Download
Title:	MGI download of germline transmission data for alleles from IMSR strain data

•

Publication

- | J:148605

First Author:	Wellcome Trust Sanger Institute
Year:	2009
Journal:	MGI Direct Data Submission
Title:	Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute

•

Publication

16602821 | J:162220

First Author:	Magdaleno S
Year:	2006
Journal:	PLoS Biol
Title:	BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume:	4
Issue:	4
Pages:	e86

•

Publication

- | J:78475

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2002

Title:	Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database

•

Publication

11217851 | J:65060

First Author:	Kawai J
Year:	2001
Journal:	Nature
Title:	Functional annotation of a full-length mouse cDNA collection.
Volume:	409
Issue:	6821
Pages:	685-90

•

Publication

- | J:293217

First Author:	GemPharmatech
Year:	2020

Title:	GemPharmatech Website.

•

Publication

21677750 | J:173534

First Author:	Skarnes WC
Year:	2011
Journal:	Nature
Title:	A conditional knockout resource for the genome-wide study of mouse gene function.
Volume:	474
Issue:	7351
Pages:	337-42

•

Publication

12466851 | J:80000

First Author:	Okazaki Y
Year:	2002
Journal:	Nature
Title:	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume:	420
Issue:	6915
Pages:	563-73

•

Publication

21267068 | J:153498

First Author:	Diez-Roux G
Year:	2011
Journal:	PLoS Biol
Title:	A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume:	9
Issue:	1
Pages:	e1000582

•

Publication

- | J:161428

First Author:	Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year:	2010

Title:	Annotation inferences using phylogenetic trees

•

Publication

- | J:63103

First Author:	Mouse Genome Database and National Center for Biotechnology Information
Year:	2000
Journal:	Database Release
Title:	Entrez Gene Load

•

Publication

- | J:262123

First Author:	Allen Institute for Brain Science
Year:	2004
Journal:	Allen Institute
Title:	Allen Brain Atlas: mouse riboprobes

•

Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

•

Publication

- | J:155721

First Author:	Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year:	2010
Journal:	Database Download
Title:	Consensus CDS project

•

Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

•

Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

•

Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

•

Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

•

Publication

20944010 | J:165791

First Author:	Ye BQ
Year:	2010
Journal:	J Immunol
Title:	Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation.
Volume:	185
Issue:	10
Pages:	6294-305

•

Protein

Q91Z69

Organism:	Mus musculus/domesticus
Length:	1062
Fragment?:	false

•

Publication

16857672 | -

First Author:	Li X
Year:	2006
Journal:	J Biol Chem
Title:	Structural basis of Robo proline-rich motif recognition by the srGAP1 Src homology 3 domain in the Slit-Robo signaling pathway.
Volume:	281
Issue:	38
Pages:	28430-7

•

Publication

22467852 | -

First Author:	Coutinho-Budd J
Year:	2012
Journal:	J Cell Sci
Title:	The F-BAR domains from srGAP1, srGAP2 and srGAP3 regulate membrane deformation differently.
Volume:	125
Issue:	Pt 14
Pages:	3390-401

•

Publication

22159416 | -

First Author:	Endris V
Year:	2011
Journal:	J Cell Sci
Title:	SrGAP3 interacts with lamellipodin at the cell membrane and regulates Rac-dependent cellular protrusions.
Volume:	124
Issue:	Pt 23
Pages:	3941-55

•

Protein Domain

IPR035648 | srGAP1/2/3_SH3

Type:

Domain

Description:

This entry represents the SH3 domain found in srGAP proteins 1, 2 and 3. srGAP1 (also called ARHGAP13) is a key GTPase activating protein (GAP) downstream of Slit-Robo pathway, and has been shown to inhibit neuronal migration and glioma cell invasion by reducing the activation of Cdc42 []. srGAP2 (ARHGAP34) regulates neuronal morphogenesis through the ability of its F-BAR domain to regulate membrane deformation and induce filopodia formation []. srGAP3 (ARHGAP14) interacts with lamellipodin at the cell membrane and regulates Rac-dependent cellular protrusions []. The SLIT-ROBO Rho GTPase-activating protein (srGAP) family consists of four members: srGAP1, -2, -3 and -4. They contain F-BAR, RhoGAP and SH3 domains. Their RhoGAP domain is involved in negative regulation of Rho GTPase activities important for cytoskeleton rearrangement []. The srGAP family members have an "inverse F-BAR"or IF-BAR domain that is distinct from other F-BAR domains such as FBP17. They are multifunctional adaptor proteins involved in various aspects of neuronal development [].

•

Publication

32973238 | J:296236

First Author:	Kandilya D
Year:	2020
Journal:	Sci Rep
Title:	High glucose alters the DNA methylation pattern of neurodevelopment associated genes in human neural progenitor cells in vitro.
Volume:	10
Issue:	1
Pages:	15676

•

Publication

23505444 | -

First Author:	Ma Y
Year:	2013
Journal:	PLoS One
Title:	The inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cells.
Volume:	8
Issue:	3
Pages:	e57865

•

Publication

20810653 | -

First Author:	Guo S
Year:	2010
Journal:	J Biol Chem
Title:	srGAP2 arginine methylation regulates cell migration and cell spreading through promoting dimerization.
Volume:	285
Issue:	45
Pages:	35133-41

•

Protein

A0A087WS73

Organism:	Mus musculus/domesticus
Length:	267
Fragment?:	true

•

Protein

Q91Z68

Organism:	Mus musculus/domesticus
Length:	150
Fragment?:	true

•

Protein

Q3TSN4

Organism:	Mus musculus/domesticus
Length:	342
Fragment?:	false

•

Protein

A0A087WS59

Organism:	Mus musculus/domesticus
Length:	451
Fragment?:	true

•

Protein

A0A087WSQ1

Organism:	Mus musculus/domesticus
Length:	649
Fragment?:	true

•

Protein

Q91Z67

Organism:	Mus musculus/domesticus
Length:	1071
Fragment?:	false

•

Protein

Q812A2

Organism:	Mus musculus/domesticus
Length:	1099
Fragment?:	false

•

Protein

D3YZW1

Organism:	Mus musculus/domesticus
Length:	1085
Fragment?:	false

•

Protein

A0A087WNM1

Organism:	Mus musculus/domesticus
Length:	858
Fragment?:	false

•

Protein

E9QN14

Organism:	Mus musculus/domesticus
Length:	1075
Fragment?:	false

•

Protein

F8VPQ4

Organism:	Mus musculus/domesticus
Length:	1099
Fragment?:	false

•

Protein

A0A2X0SZ45

Organism:	Mus musculus/domesticus
Length:	1106
Fragment?:	true

•

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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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