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Search results 201 to 251 out of 251 for Taf5

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0.02s
Type Details Score
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
GXD Expression    
Probe: MGI:7641292
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641360
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf5 -/-
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7641292
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641360
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf5 -/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7641292
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641360
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf5 +/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7641292
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641360
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf5 +/-
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7641291
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641364
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf5 -/-
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7641291
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641364
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf5 -/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7641291
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641364
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf5 +/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7641291
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641364
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf5 +/-
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7641290
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641365
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf5 -/-
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7641290
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641365
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf5 -/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7641290
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641365
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf5 +/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7641290
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641365
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf5 +/-
Detected: true
Specimen Num: 4
Publication
First Author: Bhattacharya S
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Structural analysis and dimerization potential of the human TAF5 subunit of TFIID.
Volume: 104
Issue: 4
Pages: 1189-94
Publication
First Author: Scheer E
Year: 2012
Journal: J Biol Chem
Title: TFIID TAF6-TAF9 complex formation involves the HEAT repeat-containing C-terminal domain of TAF6 and is modulated by TAF5 protein.
Volume: 287
Issue: 33
Pages: 27580-92
Protein Domain
Type: Homologous_superfamily
Description: This region is an all-alpha domain associated with the WD40 helical bundle of the TAF5 subunit of transcription factor TFIID. The domain has distant structural similarity to RNA polymerase II CTD interacting factors. It contains several conserved clefts that are likely to be critical for TFIID complex assembly []. The TAF5 subunit is present twice in the TFIID complex and is critical for the function and assembly of the complex, and the NTD2 (second N-terminal domain) and N-terminal domain are crucial for homodimerisation []. TAF5 has a paralogue gene (TAF5L) which has a redundant function [].The TATA Binding Protein (TBP) Associated Factor 5 (TAF5) is one of several TAFs that bind TBP and are involved in forming Transcription Factor IID (TFIID) complex. TFIID plays an important role in the recognition of promoter DNA and assembly of the preinitiation complex. TFIID complex is composed of the TBP and at least 13 TAFs. In yeast and human cells, TAFs have been found as components of other complexes besides TFIID [].The N-terminal domain of TAF5 has a multihelical structure with a C-terminal beta-alpha(2)-beta motif, one central buried helix and parallel β-ribbon.
Publication
First Author: Romier C
Year: 2007
Journal: J Mol Biol
Title: Crystal structure, biochemical and genetic characterization of yeast and E. cuniculi TAF(II)5 N-terminal domain: implications for TFIID assembly.
Volume: 368
Issue: 5
Pages: 1292-306
Publication
First Author: Chistiakov DA
Year: 2005
Journal: Autoimmunity
Title: The TAF5L gene on chromosome 1q42 is associated with type 1 diabetes in Russian affected patients.
Volume: 38
Issue: 4
Pages: 283-93
Allele
Name: TATA-box binding protein associated factor 5; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Protein Domain
Type: Domain
Description: This region is an all-alpha domain associated with the WD40 helical bundle of the TAF5 subunit of transcription factor TFIID. The domain has distant structural similarity to RNA polymerase II CTD interacting factors. It contains several conserved clefts that are likely to be critical for TFIID complex assembly []. The TAF5 subunit is present twice in the TFIID complex and is critical for the function and assembly of the complex, and the NTD2 (second N-terminal domain) and N-terminal domain are crucial for homodimerisation []. TAF5 has a paralogue gene (TAF5L) which has a redundant function [].The TATA Binding Protein (TBP) Associated Factor 5 (TAF5) is one of several TAFs that bind TBP and are involved in forming Transcription Factor IID (TFIID) complex. TFIID plays an important role in the recognition of promoter DNA and assembly of the preinitiation complex. TFIID complex is composed of the TBP and at least 13 TAFs. In yeast and human cells, TAFs have been found as components of other complexes besides TFIID [].
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Taf5/Taf5
Background: C57BL/6NJ-Taf5/Mmjax
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Taf5/Taf5<+>
Background: C57BL/6NJ-Taf5/Mmjax
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Papai G
Year: 2020
Journal: Nature
Title: Structure of SAGA and mechanism of TBP deposition on gene promoters.
Volume: 577
Issue: 7792
Pages: 711-716
Publication
First Author: Wang H
Year: 2020
Journal: Nature
Title: Structure of the transcription coactivator SAGA.
Volume: 577
Issue: 7792
Pages: 717-720
Publication
First Author: Nagy Z
Year: 2009
Journal: Mol Cell Biol
Title: The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.
Volume: 29
Issue: 6
Pages: 1649-60
Publication
First Author: Wu CJ
Year: 2021
Journal: Mol Plant
Title: Three functionally redundant plant-specific paralogs are core subunits of the SAGA histone acetyltransferase complex in Arabidopsis.
Volume: 14
Issue: 7
Pages: 1071-1087
Protein Domain
Type: Domain
Description: This entry represents the SEP domain found in Spt20 from yeast and human [, , ]. The Spt20 protein is part of the SAGA complex which is a large complex mediating histone deacetylation. Yeast Spt20 has been shown to play a role in structural integrity of the SAGA complex as as no intact SAGA could be purified in spt20 deletion strains. Spt20 is indispensable under endoplasmic reticulum (ER) stress conditions, being involved in the regulation of stress-responsive genes transcription. This domain interacts with LisH motif helices of Taf5 []. This domain is also found in Protein PHYTOCHROME-DEPENDENT LATE-FLOWERING (PHL), which is involved in the phytochrome B-dependent regulation of flowering [, , ].
Publication
First Author: Green MR
Year: 2000
Journal: Trends Biochem Sci
Title: TBP-associated factors (TAFIIs): multiple, selective transcriptional mediators in common complexes.
Volume: 25
Issue: 2
Pages: 59-63
Protein
Organism: Mus musculus/domesticus
Length: 530  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 529  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 784  
Fragment?: false
Publication
First Author: Endo M
Year: 2014
Journal: Plant Signal Behav
Title: Light-dependent destabilization of PHL in Arabidopsis.
Volume: 9
Issue: 3
Pages: e28118
Publication
First Author: Endo M
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: PHYTOCHROME-DEPENDENT LATE-FLOWERING accelerates flowering through physical interactions with phytochrome B and CONSTANS.
Volume: 110
Issue: 44
Pages: 18017-22