Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3506349 |
Assay Type: |
RNA in situ |
Annotation Date: |
2004-12-03 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3267927 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3507870 |
Age: |
postnatal newborn |
Image: |
2 |
|
Specimen Label: |
2 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506349 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2852723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5539365 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5667 |
|
Specimen Label: |
GUDMAP:5667 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3273028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691142 |
Age: |
postnatal adult |
Image: |
BCM_2398109 |
|
Specimen Label: |
BCM_2398109 |
Detected: |
true |
Specimen Num: |
20 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506349 |
Assay Type: |
RNA in situ |
Annotation Date: |
2004-12-03 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757721 |
|
Stage: |
TS21 |
Assay Id: |
MGI:3507870 |
Age: |
embryonic day 13.5 |
Image: |
1 |
|
Specimen Label: |
1 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506349 |
Assay Type: |
RNA in situ |
Annotation Date: |
2004-12-03 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757727 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3507870 |
Age: |
postnatal newborn |
Image: |
2 |
|
Specimen Label: |
2 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1757728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691142 |
Age: |
postnatal adult |
Image: |
BCM_1249197 |
|
Specimen Label: |
BCM_1249197 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1757728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691142 |
Age: |
postnatal adult |
Image: |
BCM_1249199 |
|
Specimen Label: |
BCM_1249199 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3281228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691142 |
Age: |
postnatal adult |
Image: |
BCM_2398107 |
|
Specimen Label: |
BCM_2398107 |
Detected: |
true |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3281228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691142 |
Age: |
postnatal adult |
Image: |
BCM_2398108 |
|
Specimen Label: |
BCM_2398108 |
Detected: |
true |
Specimen Num: |
19 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506349 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2850023 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539365 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5667 |
|
Specimen Label: |
GUDMAP:5667 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2991528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691142 |
Age: |
postnatal adult |
Image: |
BCM_1249209 |
|
Specimen Label: |
BCM_1249209 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691142 |
Age: |
postnatal adult |
Image: |
BCM_1249189 |
|
Specimen Label: |
BCM_1249189 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691142 |
Age: |
postnatal adult |
Image: |
BCM_1249191 |
|
Specimen Label: |
BCM_1249191 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691142 |
Age: |
postnatal adult |
Image: |
BCM_2398105 |
|
Specimen Label: |
BCM_2398105 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kurakin AV |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Atypical recognition consensus of CIN85/SETA/Ruk SH3 domains revealed by target-assisted iterative screening. |
Volume: |
278 |
Issue: |
36 |
Pages: |
34102-9 |
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•
•
•
•
•
|
Publication |
First Author: |
Pointud JC |
Year: |
2003 |
Journal: |
J Cell Sci |
Title: |
The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation. |
Volume: |
116 |
Issue: |
Pt 9 |
Pages: |
1847-58 |
|
•
•
•
•
•
|
Publication |
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Cheng Y |
Year: |
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Journal: |
Mol Cell Biol |
Title: |
Abnormal sperm in mice lacking the Taf7l gene. |
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7 |
Pages: |
2582-9 |
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•
•
•
•
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Publication |
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Guermah M |
Year: |
2003 |
Journal: |
Mol Cell |
Title: |
The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis. |
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4 |
Pages: |
991-1001 |
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•
•
•
•
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Publication |
First Author: |
Brand M |
Year: |
2001 |
Journal: |
EMBO J |
Title: |
UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation. |
Volume: |
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12 |
Pages: |
3187-96 |
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•
•
•
•
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Publication |
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Brand M |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction. |
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26 |
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18285-9 |
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•
•
•
•
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Publication |
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Zhao Y |
Year: |
2008 |
Journal: |
Mol Cell |
Title: |
A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing. |
Volume: |
29 |
Issue: |
1 |
Pages: |
92-101 |
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•
•
•
•
•
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Publication |
First Author: |
O'Leary J |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Global analysis of gene expression in the developing brain of Gtf2ird1 knockout mice. |
Volume: |
6 |
Issue: |
8 |
Pages: |
e23868 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alpern D |
Year: |
2014 |
Journal: |
Elife |
Title: |
TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation. |
Volume: |
3 |
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Pages: |
e03613 |
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•
•
•
•
•
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Publication |
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Tatarakis A |
Year: |
2008 |
Journal: |
Mol Cell |
Title: |
Dominant and redundant functions of TFIID involved in the regulation of hepatic genes. |
Volume: |
31 |
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4 |
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531-43 |
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•
•
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Publication |
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Jiang D |
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2020 |
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J Comp Neurol |
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Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae. |
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528 |
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5 |
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729-755 |
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•
•
•
•
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Publication |
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El-Saafin F |
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2022 |
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Cell Death Differ |
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Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. |
Volume: |
29 |
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5 |
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1013-1027 |
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•
•
•
•
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Publication |
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Bardot P |
Year: |
2017 |
Journal: |
Development |
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The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo. |
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144 |
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20 |
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3808-3818 |
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•
•
•
•
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Publication |
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2016 |
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Nat Commun |
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Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation. |
Volume: |
7 |
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Pages: |
11063 |
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•
•
•
•
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Publication |
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Kamileri I |
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2012 |
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Proc Natl Acad Sci U S A |
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Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. |
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109 |
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8 |
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2995-3000 |
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•
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Publication |
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Overbeek PA |
Year: |
2011 |
Journal: |
MGI Direct Data Submission |
Title: |
Direct Data Submission for Overbeek Lentiviral Transgenic Lines |
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•
•
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Publication |
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2006 |
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Mamm Genome |
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Quantitative trait loci for body size components in mice. |
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6 |
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526-37 |
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•
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Publication |
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Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom |
Year: |
2023 |
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Title: |
Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity |
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Publication |
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Guo G |
Year: |
2010 |
Journal: |
Dev Cell |
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Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. |
Volume: |
18 |
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4 |
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675-85 |
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Publication |
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Yokoyama S |
Year: |
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Dev Cell |
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A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
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6 |
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836-48 |
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Publication |
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Mouse Genome Informatics Scientific Curators |
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2005 |
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Title: |
Mouse Synonym Curation |
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Publication |
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Hansen J |
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2003 |
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Proc Natl Acad Sci U S A |
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A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
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Publication |
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Science |
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Mouse brain organization revealed through direct genome-scale TF expression analysis. |
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5705 |
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A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
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Publication |
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Nucleic Acids Res |
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The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
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Database issue |
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Publication |
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International Knockout Mouse Consortium |
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Database Download |
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MGI download of modified allele data from IKMC and creation of new knockout alleles |
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Publication |
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Velocigene |
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MGI Direct Data Submission |
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Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
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International Mouse Strain Resource |
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Database Download |
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MGI download of germline transmission data for alleles from IMSR strain data |
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Publication |
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Wellcome Trust Sanger Institute |
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MGI Direct Data Submission |
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Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
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GUDMAP Consortium |
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GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
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Helmholtz Zentrum Muenchen GmbH |
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MGI Direct Data Submission |
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Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
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Gene Ontology annotation through association of InterPro records with GO terms |
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Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Scheer E |
Year: |
2012 |
Journal: |
J Biol Chem |
Title: |
TFIID TAF6-TAF9 complex formation involves the HEAT repeat-containing C-terminal domain of TAF6 and is modulated by TAF5 protein. |
Volume: |
287 |
Issue: |
33 |
Pages: |
27580-92 |
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Publication |
First Author: |
Dahiya R |
Year: |
2018 |
Journal: |
FEBS J |
Title: |
Mutational analysis of TAF6 revealed the essential requirement of the histone-fold domain and the HEAT repeat domain for transcriptional activation. |
Volume: |
285 |
Issue: |
8 |
Pages: |
1491-1510 |
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Protein Domain |
Type: |
Homologous_superfamily |
Description: |
This is the C-terminal domain of the TAF6 subunit of the general transcription factor TFIID. The crystal structure reveals the presence of five conserved HEAT repeats. This region is necessary for the complexing together of the subunits TAF5, TAF6 and TAF9 [, ]. |
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Protein Domain |
Type: |
Domain |
Description: |
This is the C-terminal domain of the TAF6 subunit of the general transcription factor TFIID. The crystal structure reveals the presence of five conserved HEAT repeats. This region is necessary for the complexing together of the subunits TAF5, TAF6 and TAF9 [, ]. |
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Publication |
First Author: |
Xie X |
Year: |
1996 |
Journal: |
Nature |
Title: |
Structural similarity between TAFs and the heterotetrameric core of the histone octamer. |
Volume: |
380 |
Issue: |
6572 |
Pages: |
316-22 |
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Publication |
First Author: |
Cler E |
Year: |
2009 |
Journal: |
Cell Mol Life Sci |
Title: |
Recent advances in understanding the structure and function of general transcription factor TFIID. |
Volume: |
66 |
Issue: |
13 |
Pages: |
2123-34 |
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Publication |
First Author: |
Gangloff YG |
Year: |
2001 |
Journal: |
Trends Biochem Sci |
Title: |
The histone fold is a key structural motif of transcription factor TFIID. |
Volume: |
26 |
Issue: |
4 |
Pages: |
250-7 |
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Publication |
First Author: |
Frontini M |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9. |
Volume: |
25 |
Issue: |
11 |
Pages: |
4638-49 |
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Protein Domain |
Type: |
Family |
Description: |
Human transcription initiation factor TFIID is composed of the TATA-binding polypeptide (TBP) and at least 13 TBP-associated factors (TAFs) that collectively or individually are involved in activator-dependent transcription [, , ]. This entry represents the N terminus of the 31kDa subunit (42kDa in Drosophila) of transcription initiation factor IID (TAFII31), also known astranscription initiation factor TFIID subunit 9 (TAF9). It has been shown that TAF9 interacts directly with different transcription factors such as p53, herpes simplex virus activator vp16 and the basal transcription factor TFIIB. Binding to p53 is an essential requirement for p53 mediated transcription activation.TAF9 is a component other TBP-free TAF complexes containing the GCN5-type histone acetyltransferase. Several TAFs interact via histone-fold (HFD) motifs; HFD is the interaction motif involved in heterodimerization of the core histones and their assembly into nucleosome octamers. The minimal HFD contains three α-helices linked by two loops and is found in core histones, TAFS and many other transcription factors. TFIID has a histone octamer-like substructure. TFIID has a histone octamer-like substructure. TAF9 is a shared subunit of both, histone acetyltransferase complex (SAGA) and TFIID complexes. TAF9 domain interacts with TAF6 to form a novel histone-like heterodimer that is structurally related to the histone H3 and H4 oligomer [, , , ]. |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
249
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
264
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
80
 |
Fragment?: |
true |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
293
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
181
 |
Fragment?: |
true |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
155
 |
Fragment?: |
true |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
170
 |
Fragment?: |
true |
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Publication |
First Author: |
Hisatake K |
Year: |
1995 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Evolutionary conservation of human TATA-binding-polypeptide-associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors. |
Volume: |
92 |
Issue: |
18 |
Pages: |
8195-9 |
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Publication |
First Author: |
Tora L |
Year: |
2002 |
Journal: |
Genes Dev |
Title: |
A unified nomenclature for TATA box binding protein (TBP)-associated factors (TAFs) involved in RNA polymerase II transcription. |
Volume: |
16 |
Issue: |
6 |
Pages: |
673-5 |
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Publication |
First Author: |
Green MR |
Year: |
2000 |
Journal: |
Trends Biochem Sci |
Title: |
TBP-associated factors (TAFIIs): multiple, selective transcriptional mediators in common complexes. |
Volume: |
25 |
Issue: |
2 |
Pages: |
59-63 |
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