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Search results 201 to 300 out of 661 for Tec

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Type Details Score
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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UniProt Feature
UniProt Feature
Begin: 81
Description: Phosphotyrosine; by TEC
Type: modified residue
End: 81
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UniProt Feature
UniProt Feature
Begin: 1
Description: Tyrosine-protein kinase Tec
Type: chain
End: 630
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Publication
11684687 | -
First Author: Pursglove SE
Year: 2002
Journal: J Biol Chem
Title: The solution structure and intramolecular associations of the Tec kinase SRC homology 3 domain.
Volume: 277
Issue: 1
Pages: 755-62
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Protein
F6W1T9
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: true
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Gene
108706583 | tec.S
Type: gene
Organism: frog, African clawed
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Gene
734996 | tec.L
Type: gene
Organism: frog, African clawed
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Protein
D6RJM5
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: false
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Allele
Tec<em1Smoc> | MGI:7292720
Name: tec protein tyrosine kinase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Protein
P24604
Organism: Mus musculus/domesticus
Length: 630  
Fragment?: false
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Publication
21362140 | J:190802
First Author: Ellmeier W
Year: 2011
Journal: FEBS J
Title: Tec family kinases: regulation of FcεRI-mediated mast-cell activation.
Volume: 278
Issue: 12
Pages: 1990-2000
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Publication
15123627 | J:91612
First Author: Fischer AM
Year: 2004
Journal: J Biol Chem
Title: Regulation of CXC chemokine receptor 4-mediated migration by the Tec family tyrosine kinase ITK.
Volume: 279
Issue: 28
Pages: 29816-20
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Publication
11702066 | J:72934
First Author: Schaeffer EM
Year: 2001
Journal: Nat Immunol
Title: Mutation of Tec family kinases alters T helper cell differentiation.
Volume: 2
Issue: 12
Pages: 1183-8
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Publication
28439878 | J:249605
First Author: Brunk F
Year: 2017
Journal: Eur J Immunol
Title: Dissecting and modeling the emergent murine TEC compartment during ontogeny.
Volume: 47
Issue: 7
Pages: 1153-1159
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Publication
11015440 | J:115113
First Author: Schaeffer EM
Year: 2000
Journal: J Exp Med
Title: Tec family kinases modulate thresholds for thymocyte development and selection.
Volume: 192
Issue: 7
Pages: 987-1000
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Protein
P24604-3
Organism: Mus musculus/domesticus
Length: 624  
Fragment?: false
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Protein
P24604-2
Organism: Mus musculus/domesticus
Length: 527  
Fragment?: false
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Protein
P24604-4
Organism: Mus musculus/domesticus
Length: 602  
Fragment?: false
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Protein
P24604-6
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: false
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Protein
P24604-5
Organism: Mus musculus/domesticus
Length: 608  
Fragment?: false
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Protein
A0A0R4J1V5
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: false
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Protein
A0A0J9YV29
Organism: Mus musculus/domesticus
Length: 44  
Fragment?: true
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Publication
20543088 | -
First Author: Zhang MJ
Year: 2010
Journal: Am J Physiol Heart Circ Physiol
Title: Stress signaling by Tec tyrosine kinase in the ischemic myocardium.
Volume: 299
Issue: 3
Pages: H713-22
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Publication
12614356 | J:82480
 
First Author: Lucas JA
Year: 2003
Journal: Immunol Rev
Title: The role of Tec family kinases in T cell development and function.
Volume: 191
Pages: 119-38
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Publication
18281276 | J:136557
First Author: Lee SH
Year: 2008
Journal: J Biol Chem
Title: The tec family tyrosine kinase Btk Regulates RANKL-induced osteoclast maturation.
Volume: 283
Issue: 17
Pages: 11526-34
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Strain
MGI:6355243 | C57BL/6JSmoc-Tec<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
9872994 | -
First Author: Yang WC
Year: 1999
Journal: J Biol Chem
Title: The role of Tec protein-tyrosine kinase in T cell signaling.
Volume: 274
Issue: 2
Pages: 607-17
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Publication
16237085 | J:119338
First Author: Finkelstein LD
Year: 2005
Journal: J Immunol
Title: Tec kinases regulate TCR-mediated recruitment of signaling molecules and integrin-dependent cell adhesion.
Volume: 175
Issue: 9
Pages: 5923-30
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Publication
8632917 | J:31642
First Author: Ohta Y
Year: 1996
Journal: Oncogene
Title: Human Txk: genomic organization, structure and contiguous physical linkage with the Tec gene.
Volume: 12
Issue: 4
Pages: 937-42
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Publication
10213685 | J:54449
First Author: Schaeffer EM
Year: 1999
Journal: Science
Title: Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity.
Volume: 284
Issue: 5414
Pages: 638-41
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Publication
21362141 | J:190801
First Author: Qi Q
Year: 2011
Journal: FEBS J
Title: Tec family kinases: Itk signaling and the development of NKT αβ and γδ T cells.
Volume: 278
Issue: 12
Pages: 1970-9
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Publication
16860759 | J:113408
First Author: Atherly LO
Year: 2006
Journal: Immunity
Title: The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells.
Volume: 25
Issue: 1
Pages: 79-91
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Publication
30770814 | J:275414
First Author: Cho HS
Year: 2019
Journal: Nat Commun
Title: The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine.
Volume: 10
Issue: 1
Pages: 784
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Publication
10562318 | J:58493
First Author: Sommers CL
Year: 1999
Journal: J Exp Med
Title: A role for the Tec family tyrosine kinase Txk in T cell activation and thymocyte selection.
Volume: 190
Issue: 10
Pages: 1427-38
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Publication
14647425 | J:88384
First Author: Gérard A
Year: 2004
Journal: Oncogene
Title: Functional interaction of RasGAP-binding proteins Dok-1 and Dok-2 with the Tec protein tyrosine kinase.
Volume: 23
Issue: 8
Pages: 1594-8
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Allele
Tec<+> | MGI:2432154
   
Name: tec protein tyrosine kinase; wild type
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Publication
8877094 | -
First Author: Miyazato A
Year: 1996
Journal: Cell Growth Differ
Title: Tec protein tyrosine kinase is involved in the signaling mechanism of granulocyte colony-stimulating factor receptor.
Volume: 7
Issue: 9
Pages: 1135-9
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Publication
10382746 | -
First Author: Yang WC
Year: 1999
Journal: Eur J Immunol
Title: Tec kinase is involved in transcriptional regulation of IL-2 and IL-4 in the CD28 pathway.
Volume: 29
Issue: 6
Pages: 1842-9
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Publication
15214045 | -
First Author: Garçon F
Year: 2004
Journal: Eur J Immunol
Title: The SH3 domain of Tec kinase is essential for its targeting to activated CD28 costimulatory molecule.
Volume: 34
Issue: 7
Pages: 1972-80
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Publication
21094130 | -
First Author: Li F
Year: 2011
Journal: Biochem Biophys Res Commun
Title: TEC protein tyrosine kinase is involved in the Erk signaling pathway induced by HGF.
Volume: 404
Issue: 1
Pages: 79-85
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Publication
15771581 | -
 
First Author: Berg LJ
Year: 2005
Journal: Annu Rev Immunol
Title: Tec family kinases in T lymphocyte development and function.
Volume: 23
Pages: 549-600
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Publication
18523250 | J:137249
First Author: Iyer AS
Year: 2008
Journal: J Immunol
Title: The Tec family kinase, IL-2-inducible T cell kinase, differentially controls mast cell responses.
Volume: 180
Issue: 12
Pages: 7869-77
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Publication
19416854 | J:148531
First Author: Felices M
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo.
Volume: 106
Issue: 20
Pages: 8308-13
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Publication
23378428 | J:193616
First Author: Yin CC
Year: 2013
Journal: J Immunol
Title: The Tec kinase ITK regulates thymic expansion, emigration, and maturation of γδ NKT cells.
Volume: 190
Issue: 6
Pages: 2659-69
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Publication
23982207 | J:260002
First Author: Joseph RE
Year: 2013
Journal: Sci Signal
Title: Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases.
Volume: 6
Issue: 290
Pages: ra76
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Publication
34566971 | J:311199
 
First Author: Thelen F
Year: 2021
Journal: Front Immunol
Title: The Tec Kinase Itk Integrates Naïve T Cell Migration and In Vivo Homeostasis.
Volume: 12
Pages: 716405
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Publication
30061015 | J:273960
 
First Author: Lau CI
Year: 2018
Journal: J Autoimmun
Title: Foxa1 and Foxa2 in thymic epithelial cells (TEC) regulate medullary TEC and regulatory T-cell maturation.
Volume: 93
Pages: 131-138
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Publication
18025201 | J:154808
First Author: Lucas JA
Year: 2007
Journal: J Immunol
Title: Subtle defects in pre-TCR signaling in the absence of the Tec kinase Itk.
Volume: 179
Issue: 11
Pages: 7561-7
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Publication
18292523 | J:131540
First Author: Felices M
Year: 2008
Journal: J Immunol
Title: The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival.
Volume: 180
Issue: 5
Pages: 3007-18
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Publication
16860760 | J:113409
First Author: Broussard C
Year: 2006
Journal: Immunity
Title: Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk.
Volume: 25
Issue: 1
Pages: 93-104
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Publication
21362139 | J:190803
First Author: Gomez-Rodriguez J
Year: 2011
Journal: FEBS J
Title: Tec family kinases Itk and Rlk / Txk in T lymphocytes: cross-regulation of cytokine production and T-cell fates.
Volume: 278
Issue: 12
Pages: 1980-9
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Publication
9473212 | -
First Author: Yamashita Y
Year: 1998
Journal: Blood
Title: Tec and Jak2 kinases cooperate to mediate cytokine-driven activation of c-fos transcription.
Volume: 91
Issue: 5
Pages: 1496-507
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Publication
8621063 | -
First Author: Mano H
Year: 1996
Journal: FASEB J
Title: Tec protein-tyrosine kinase is an effector molecule of Lyn protein-tyrosine kinase.
Volume: 10
Issue: 5
Pages: 637-42
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Publication
16631752 | J:127466
First Author: Hao S
Year: 2006
Journal: FEBS Lett
Title: A kinase independent function for Tec kinase ITK in regulating antigen receptor induced serum response factor activation.
Volume: 580
Issue: 11
Pages: 2691-7
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Publication
21518255 | J:190798
First Author: Hussain A
Year: 2011
Journal: FEBS J
Title: TEC family kinases in health and disease--loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK.
Volume: 278
Issue: 12
Pages: 2001-10
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Publication
23011795 | J:190333
First Author: Nayar R
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation.
Volume: 109
Issue: 41
Pages: E2794-802
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Publication
7579892 | J:27723
First Author: Haire RN
Year: 1995
Journal: Mamm Genome
Title: The murine form of TXK, a novel TEC kinase expressed in thymus maps to chromosome 5.
Volume: 6
Issue: 7
Pages: 476-80
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Publication
29867988 | J:309668
 
First Author: Montero-Herradón S
Year: 2018
Journal: Front Immunol
Title: Altered Maturation of Medullary TEC in EphB-Deficient Thymi Is Recovered by RANK Signaling Stimulation.
Volume: 9
Pages: 1020
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Publication
10556826 | J:243546
First Author: Su YW
Year: 1999
Journal: Eur J Immunol
Title: Interaction of SLP adaptors with the SH2 domain of Tec family kinases.
Volume: 29
Issue: 11
Pages: 3702-11
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Publication
34452995 | J:309571
 
First Author: Gallagher MP
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Hierarchy of signaling thresholds downstream of the T cell receptor and the Tec kinase ITK.
Volume: 118
Issue: 35
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Publication
15817477 | -
First Author: Kane LP
Year: 2005
Journal: J Biol Chem
Title: Dynamic regulation of Tec kinase localization in membrane-proximal vesicles of a T cell clone revealed by total internal reflection fluorescence and confocal microscopy.
Volume: 280
Issue: 23
Pages: 21949-54
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Publication
17383541 | -
 
First Author: Felices M
Year: 2007
Journal: Adv Immunol
Title: Tec kinases in T cell and mast cell signaling.
Volume: 93
Pages: 145-84
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Publication
12573241 | -
First Author: Nore BF
Year: 2003
Journal: Biochim Biophys Acta
Title: Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases.
Volume: 1645
Issue: 2
Pages: 123-32
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Allele
Tec<tm1Welm> | MGI:2450883
Name: tec protein tyrosine kinase; targeted mutation 1, Wilfred Ellmeier
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Tec<Gt(OST176962)Lex> | MGI:4216735
 
Name: tec protein tyrosine kinase; gene trap OST176962, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Tec<em2Cya> | MGI:7587010
Name: tec protein tyrosine kinase; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Interaction Experiment
Yoshida K (2000)
Description: Mediation by the protein-tyrosine kinase Tec of signaling between the B cell antigen receptor and Dok-1.
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Publication
32493815 | J:291694
First Author: Conley JM
Year: 2020
Journal: J Immunol
Title: Activation of the Tec Kinase ITK Controls Graded IRF4 Expression in Response to Variations in TCR Signal Strength.
Volume: 205
Issue: 2
Pages: 335-345
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Publication
8070576 | -
First Author: Vihinen M
Year: 1994
Journal: FEBS Lett
Title: Tec homology (TH) adjacent to the PH domain.
Volume: 350
Issue: 2-3
Pages: 263-5
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Publication
21212279 | J:170527
First Author: Iyer AS
Year: 2011
Journal: J Biol Chem
Title: Absence of Tec family kinases interleukin-2 inducible T cell kinase (Itk) and Bruton's tyrosine kinase (Btk) severely impairs Fc epsilonRI-dependent mast cell responses.
Volume: 286
Issue: 11
Pages: 9503-13
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Publication
10518561 | -
First Author: Ohya K
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning of a docking protein, BRDG1, that acts downstream of the Tec tyrosine kinase.
Volume: 96
Issue: 21
Pages: 11976-81
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Publication
29744875 | J:312818
First Author: Pham TL
Year: 2018
Journal: J Cell Physiol
Title: Expression of Pannexin 1 and Pannexin 3 during skeletal muscle development, regeneration, and Duchenne muscular dystrophy.
Volume: 233
Issue: 10
Pages: 7057-7070
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Publication
30774584 | J:341572
 
First Author: Krol A
Year: 2019
Journal: Front Neural Circuits
Title: Two eARCHT3.0 Lines for Optogenetic Silencing of Dopaminergic and Serotonergic Neurons.
Volume: 13
Pages: 4
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Publication
17624943 | -
 
First Author: Gomez-Rodriguez J
Year: 2007
Journal: Immunol Rev
Title: Tec kinases, actin, and cell adhesion.
Volume: 218
Pages: 45-64
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Publication
7543527 | J:27201
First Author: Sugihara S
Year: 1995
Journal: J Immunol
Title: Self-thyroid epithelial cell (TEC)-reactive CD8+ T cell lines/clones derived from autoimmune thyroiditis lesions. They recognize self-thyroid antigens directly on TEC to exhibit T helper cell 1-type lymphokine production and cytotoxicity against TEC.
Volume: 155
Issue: 3
Pages: 1619-28
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Allele
Tec<tm1e(EUCOMM)Wtsi> | MGI:4441793
Name: tec protein tyrosine kinase; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Tec<tm1a(EUCOMM)Wtsi> | MGI:4441893
Name: tec protein tyrosine kinase; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Tec<em1(IMPC)Ccpcz> | MGI:6388374
Name: tec protein tyrosine kinase; endonuclease-mediated mutation 1, Institute of Molecular Genetics
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7589121 | C57BL/6J-Tec<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Tec/Tec
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Protein
Q9QZB6
Organism: Mus musculus/domesticus
Length: 627  
Fragment?: false
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Protein
Q9QZB6-2
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
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Publication
17479128 | -
First Author: Berg LJ
Year: 2007
Journal: Nat Rev Immunol
Title: Signalling through TEC kinases regulates conventional versus innate CD8(+) T-cell development.
Volume: 7
Issue: 6
Pages: 479-85
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Publication
19290924 | -
First Author: Prince AL
Year: 2009
Journal: Immunol Rev
Title: The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development.
Volume: 228
Issue: 1
Pages: 115-31
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Publication
17060314 | -
First Author: Qi Q
Year: 2006
Journal: J Biol Chem
Title: Tec kinase Itk forms membrane clusters specifically in the vicinity of recruiting receptors.
Volume: 281
Issue: 50
Pages: 38529-34
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Publication
20206686 | -
First Author: Bradshaw JM
Year: 2010
Journal: Cell Signal
Title: The Src, Syk, and Tec family kinases: distinct types of molecular switches.
Volume: 22
Issue: 8
Pages: 1175-84
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Publication
20305788 | J:158899
First Author: Berge T
Year: 2010
Journal: PLoS One
Title: T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.
Volume: 5
Issue: 3
Pages: e9761
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Publication
11859127 | -
First Author: Takeba Y
Year: 2002
Journal: J Immunol
Title: Txk, a member of nonreceptor tyrosine kinase of Tec family, acts as a Th1 cell-specific transcription factor and regulates IFN-gamma gene transcription.
Volume: 168
Issue: 5
Pages: 2365-70
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Publication
20052711 | -
First Author: Marcotte DJ
Year: 2010
Journal: Protein Sci
Title: Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases.
Volume: 19
Issue: 3
Pages: 429-39
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Publication
17420479 | -
First Author: Bogin Y
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK.
Volume: 104
Issue: 16
Pages: 6638-43
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Publication
17177976 | -
First Author: Maruyama T
Year: 2007
Journal: Clin Exp Immunol
Title: Txk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cells.
Volume: 147
Issue: 1
Pages: 164-75
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Strain
MGI:7853186 | C57BL/6NCrl-Tec<em1(IMPC)Ccpcz>/Ph
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Coding Gene
MGI:1352457 | Nr4a3
Type: protein_coding_gene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Btk/Btk Tec/Tec
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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HT Experiment
GSE220270 | Klf6 is required in thymic epithelial cells for normal thymus development [scRNA-seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
8985255 | -
First Author: Andreotti AH
Year: 1997
Journal: Nature
Title: Regulatory intramolecular association in a tyrosine kinase of the Tec family.
Volume: 385
Issue: 6611
Pages: 93-7
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Publication
8943565 | -
First Author: King PD
Year: 1996
Journal: Int Immunol
Title: CD2 signaling in T cells involves tyrosine phosphorylation and activation of the Tec family kinase, EMT/ITK/TSK.
Volume: 8
Issue: 11
Pages: 1707-14
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Publication
15492005 | -
First Author: Tomlinson MG
Year: 2004
Journal: J Biol Chem
Title: SHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase.
Volume: 279
Issue: 53
Pages: 55089-96
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