Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:6185031 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191446 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Tcfcp2 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506718 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796223 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539697 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:12171 |
|
Specimen Label: |
GUDMAP:12171 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384673 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-16 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3148828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7384683 |
Age: |
postnatal week 12 |
|
|
Specimen Label: |
3C Maturation stage |
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384673 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-16 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3148828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7384683 |
Age: |
postnatal week 12 |
|
|
Specimen Label: |
3D Release stage |
Detected: |
false |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384673 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-16 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3148828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7384683 |
Age: |
postnatal week 12 |
|
|
Specimen Label: |
3G Maturation stage |
Detected: |
false |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384673 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-16 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3148828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7384683 |
Age: |
postnatal week 12 |
|
|
Specimen Label: |
3H Release stage |
Detected: |
false |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384673 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-16 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3148828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7384683 |
Age: |
postnatal week 12 |
|
|
Specimen Label: |
Table 1 Elongation stage |
Detected: |
false |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384673 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-16 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3148828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7384683 |
Age: |
postnatal week 12 |
|
|
Specimen Label: |
Table 1 Grouping stage |
Detected: |
false |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384673 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-16 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3148828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7384683 |
Age: |
postnatal week 12 |
|
|
Specimen Label: |
Table 1 Maturation stage |
Detected: |
false |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384673 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-16 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3148828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7384683 |
Age: |
postnatal week 12 |
|
|
Specimen Label: |
Table 1 Release stage |
Detected: |
false |
Specimen Num: |
12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kang HC |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
Erythroid cell-specific alpha-globin gene regulation by the CP2 transcription factor family. |
Volume: |
25 |
Issue: |
14 |
Pages: |
6005-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rodda S |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
CRTR-1, a developmentally regulated transcriptional repressor related to the CP2 family of transcription factors. |
Volume: |
276 |
Issue: |
5 |
Pages: |
3324-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lim LC |
Year: |
1993 |
Journal: |
J Biol Chem |
Title: |
Characterization of the molecularly cloned murine alpha-globin transcription factor CP2. |
Volume: |
268 |
Issue: |
24 |
Pages: |
18008-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cunningham JM |
Year: |
1995 |
Journal: |
Genomics |
Title: |
The human transcription factor CP2 (TFCP2), a component of the human gamma-globin stage selector protein, maps to chromosome region 12q13 and is within 250 kb of the NF-E2 gene. |
Volume: |
30 |
Issue: |
2 |
Pages: |
398-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu Y |
Year: |
2007 |
Journal: |
Cell Death Differ |
Title: |
Intracellular domains of amyloid precursor-like protein 2 interact with CP2 transcription factor in the nucleus and induce glycogen synthase kinase-3beta expression. |
Volume: |
14 |
Issue: |
1 |
Pages: |
79-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim MY |
Year: |
2018 |
Journal: |
Nucleic Acids Res |
Title: |
Mbd2-CP2c loop drives adult-type globin gene expression and definitive erythropoiesis. |
Volume: |
46 |
Issue: |
10 |
Pages: |
4933-4949 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim JS |
Year: |
2016 |
Journal: |
Acta Histochem |
Title: |
Reciprocal localization of transcription factors YY1 and CP2c in spermatogonial stem cells and their putative roles during spermatogenesis. |
Volume: |
118 |
Issue: |
7 |
Pages: |
685-692 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saxena UH |
Year: |
2009 |
Journal: |
Mol Cell Biol |
Title: |
Phosphorylation by cyclin C/cyclin-dependent kinase 2 following mitogenic stimulation of murine fibroblasts inhibits transcriptional activity of LSF during G1 progression. |
Volume: |
29 |
Issue: |
9 |
Pages: |
2335-45 |
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•
•
•
•
•
|
Publication |
First Author: |
Porta-de-la-Riva M |
Year: |
2011 |
Journal: |
Biochem J |
Title: |
TFCP2c/LSF/LBP-1c is required for Snail1-induced fibronectin gene expression. |
Volume: |
435 |
Issue: |
3 |
Pages: |
563-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ramamurthy L |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
Targeted disruption of the CP2 gene, a member of the NTF family of transcription factors. |
Volume: |
276 |
Issue: |
11 |
Pages: |
7836-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kudryavtseva EI |
Year: |
2003 |
Journal: |
Dev Dyn |
Title: |
Identification and characterization of Grainyhead-like epithelial transactivator (GET-1), a novel mammalian Grainyhead-like factor. |
Volume: |
226 |
Issue: |
4 |
Pages: |
604-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Swendeman SL |
Year: |
1994 |
Journal: |
J Biol Chem |
Title: |
Characterization of the genomic structure, chromosomal location, promoter, and development expression of the alpha-globin transcription factor CP2. |
Volume: |
269 |
Issue: |
15 |
Pages: |
11663-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
University of California, Davis |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the University of California, Davis |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Guo G |
Year: |
2010 |
Journal: |
Dev Cell |
Title: |
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. |
Volume: |
18 |
Issue: |
4 |
Pages: |
675-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
RIKEN Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yokoyama S |
Year: |
2009 |
Journal: |
Dev Cell |
Title: |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
Volume: |
17 |
Issue: |
6 |
Pages: |
836-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gray PA |
Year: |
2004 |
Journal: |
Science |
Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
Volume: |
306 |
Issue: |
5705 |
Pages: |
2255-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
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Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
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Title: |
GemPharmatech Website. |
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|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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•
•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
•
•
•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384666 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-17 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3148228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7384819 |
Age: |
postnatal week 12 |
|
Note: |
Co-localization of Yy1 and Tfcp2 in spermatogonia. |
Specimen Label: |
4C |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384666 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-17 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3148228 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7384819 |
Age: |
postnatal week 12 |
|
Note: |
Nuclear co-localization of Yy1 and Tfcp2 in spermatogonia at Grouping stage seminiferous tubule. |
Specimen Label: |
4B |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384666 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-17 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3148428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7384819 |
Age: |
postnatal week 12 |
|
Note: |
Yy1 and Tfcp2 localized in the nucleus and cytoplasm of spermatocytes, respectively. |
Specimen Label: |
4A1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384666 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-17 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3148428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7384819 |
Age: |
postnatal week 12 |
|
Note: |
Yy1 and Tfcp2 localized in the nucleus and cytoplasm of spermatocytes, respectively. |
Specimen Label: |
4A2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kokoszynska K |
Year: |
2008 |
Journal: |
Cell Cycle |
Title: |
The fold recognition of CP2 transcription factors gives new insights into the function and evolution of tumor suppressor protein p53. |
Volume: |
7 |
Issue: |
18 |
Pages: |
2907-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sato Y |
Year: |
2010 |
Journal: |
Mol Cell Biochem |
Title: |
The male-determining gene SRY is a hybrid of DGCR8 and SOX3, and is regulated by the transcription factor CP2. |
Volume: |
337 |
Issue: |
1-2 |
Pages: |
267-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jane SM |
Year: |
1995 |
Journal: |
EMBO J |
Title: |
Hemoglobin switching in man and chicken is mediated by a heteromeric complex between the ubiquitous transcription factor CP2 and a developmentally specific protein. |
Volume: |
14 |
Issue: |
1 |
Pages: |
97-105 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
TFCP2 (CP2 transcription factor) is a critical regulator of erythroid gene expression [, ]. It also regulates the expressison of the male-dominant sex-determining gene SRY []. TFCP2 can interact with NF-E4 proteins forming heteromeric stage selector protein complex (SSP); this complex is able to bind stage selector element (SSE) and regulate embryonic globin expression in fetal-erythroid cells [].TFCP2 has an N-terminal DNA-binding CP2 domain, a central predicted SAM domain and a C-terminal dimerization domain. This entry represents the SAM domain. |
|
•
•
•
•
•
|
Publication |
First Author: |
Kotarba G |
Year: |
2018 |
Journal: |
Cancer Lett |
Title: |
TFCP2/TFCP2L1/UBP1 transcription factors in cancer. |
Volume: |
420 |
|
Pages: |
72-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hsu WH |
Year: |
2023 |
Journal: |
Cancer Discov |
Title: |
Oncogenic KRAS Drives Lipofibrogenesis to Promote Angiogenesis and Colon Cancer Progression. |
Volume: |
13 |
Issue: |
12 |
Pages: |
2652-2673 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
502
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
326
 |
Fragment?: |
true |
|
•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
505
 |
Fragment?: |
false |
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