Type |
Details |
Score |
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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|
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
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•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
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•
•
•
•
•
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Publication |
First Author: |
Kim CM |
Year: |
2016 |
Journal: |
Appl Biochem Biotechnol |
Title: |
Functional Analysis of CP2-Like Domain and SAM-Like Domain in TFCP2L1, Novel Pluripotency Factor of Embryonic Stem Cells. |
Volume: |
179 |
Issue: |
4 |
Pages: |
650-8 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
TFCP2L1 (also known as LBP9) is involved in transcriptional regulation from early development to terminal differentiation. In mice, it is required for proper maturation of the duct of the salivary gland and the kidney []. In humans, it is involved in the regulation of P450scc (the cholesterol side-chain cleavage enzyme, cytochrome) in placental JEG-3 cells []. TFCP2L1 is also involved in establishment and maintenance of pluripotency in embryonic stem cells through formation of complex transcriptional networks with the other transcription factors, OCT4, SOX2, and NANOG []. TFCP2L1 contains an N-terminal DNA-binding CP2 domain, a central predicted SAM domain and a C-terminal dimerization domain. In vitro, TFCP2L1 is hexamerized in solution via the C-terminal SAM domain []. This entry represents the SAM domain found in TFCP2L1. |
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•
•
•
•
•
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Publication |
First Author: |
Huang N |
Year: |
2005 |
Journal: |
Mol Endocrinol |
Title: |
LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells. |
Volume: |
19 |
Issue: |
2 |
Pages: |
409-20 |
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•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
479
 |
Fragment?: |
false |
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•
•
•
•
•
|
Publication |
First Author: |
Sardina JL |
Year: |
2018 |
Journal: |
Cell Stem Cell |
Title: |
Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate. |
Volume: |
23 |
Issue: |
5 |
Pages: |
727-741.e9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yan H |
Year: |
2021 |
Journal: |
EMBO Rep |
Title: |
Fatty acid oxidation is required for embryonic stem cell survival during metabolic stress. |
Volume: |
22 |
Issue: |
6 |
Pages: |
e52122 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kotarba G |
Year: |
2018 |
Journal: |
Cancer Lett |
Title: |
TFCP2/TFCP2L1/UBP1 transcription factors in cancer. |
Volume: |
420 |
|
Pages: |
72-79 |
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•
•
•
•
•
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