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Search results 201 to 300 out of 382 for Tgm6

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Type Details Score
Publication
First Author: Katlinskaya YV
Year: 2016
Journal: Cell Rep
Title: Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression.
Volume: 15
Issue: 1
Pages: 171-80
Publication
First Author: Cesarini V
Year: 2017
Journal: Oncogene
Title: Sox2 is not required for melanomagenesis, melanoma growth and melanoma metastasis in vivo.
Volume: 36
Issue: 31
Pages: 4508-4515
Publication
First Author: Shurin GV
Year: 2019
Journal: Cancer Res
Title: Melanoma-Induced Reprogramming of Schwann Cell Signaling Aids Tumor Growth.
Volume: 79
Issue: 10
Pages: 2736-2747
Publication
First Author: Kim SH
Year: 2017
Journal: J Invest Dermatol
Title: Phenformin Inhibits Myeloid-Derived Suppressor Cells and Enhances theĀ Anti-Tumor Activity of PD-1 Blockade inĀ Melanoma.
Volume: 137
Issue: 8
Pages: 1740-1748
Publication  
First Author: Huang F
Year: 2021
Journal: J Clin Invest
Title: Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses.
Volume: 131
Issue: 8
Publication
First Author: Lui JW
Year: 2019
Journal: J Cancer
Title: The Efficiency of Verteporfin as a Therapeutic Option in Pre-Clinical Models of Melanoma.
Volume: 10
Issue: 1
Pages: 1-10
Publication
First Author: Luo X
Year: 2014
Journal: Cell Rep
Title: Isolation and molecular characterization of circulating melanoma cells.
Volume: 7
Issue: 3
Pages: 645-53
Publication
First Author: Di Leo L
Year: 2021
Journal: Nat Commun
Title: Loss of Ambra1 promotes melanoma growth and invasion.
Volume: 12
Issue: 1
Pages: 2550
Publication
First Author: Brady DC
Year: 2017
Journal: Cancer Res
Title: Copper Chelation Inhibits BRAFV600E-Driven Melanomagenesis and Counters Resistance to BRAFV600E and MEK1/2 Inhibitors.
Volume: 77
Issue: 22
Pages: 6240-6252
Publication
First Author: Long JE
Year: 2019
Journal: Cell Death Differ
Title: Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation.
Volume: 26
Issue: 11
Pages: 2416-2429
Publication
First Author: Perna D
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model.
Volume: 112
Issue: 6
Pages: E536-45
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Strain
Attribute String: mutant stock, congenic, transgenic, targeted mutation
Strain
Attribute String: transgenic, targeted mutation, mutant strain, congenic
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Publication
First Author: Le Gal K
Year: 2015
Journal: Sci Transl Med
Title: Antioxidants can increase melanoma metastasis in mice.
Volume: 7
Issue: 308
Pages: 308re8
Publication
First Author: Crawford M
Year: 2017
Journal: Biol Open
Title: A reporter mouse model for in vivo tracing and in vitro molecular studies of melanocytic lineage cells and their diseases.
Volume: 6
Issue: 8
Pages: 1219-1228
Publication
First Author: Peng W
Year: 2016
Journal: Cancer Discov
Title: Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.
Volume: 6
Issue: 2
Pages: 202-16
Publication
First Author: Rahman H
Year: 2021
Journal: J Invest Dermatol
Title: Aspirin Protects Melanocytes and Keratinocytes against UVB-Induced DNA Damage InĀ Vivo.
Volume: 141
Issue: 1
Pages: 132-141.e3
Publication
First Author: Pandita A
Year: 2021
Journal: Am J Pathol
Title: Intussusceptive Angiogenesis in Human Metastatic Malignant Melanoma.
Volume: 191
Issue: 11
Pages: 2023-2038
Publication
First Author: Muinonen-Martin AJ
Year: 2014
Journal: PLoS Biol
Title: Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal.
Volume: 12
Issue: 10
Pages: e1001966
Publication
First Author: Chen HC
Year: 2018
Journal: Oncotarget
Title: Activation of Grm1 expression by mutated BRaf (V600E) in vitro and in vivo.
Volume: 9
Issue: 5
Pages: 5861-5875
Publication
First Author: Claps G
Year: 2016
Journal: Cell Rep
Title: A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis.
Volume: 15
Issue: 9
Pages: 1884-92
Publication
First Author: Pastura P
Year: 2024
Journal: Pediatr Blood Cancer
Title: NRAS(Q61R) mutation drives elevated angiopoietin-2 expression in human endothelial cells and a genetic mouse model.
Volume: 71
Issue: 7
Pages: e31032
Publication
First Author: Liu S
Year: 2018
Journal: Nat Commun
Title: Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis.
Volume: 9
Issue: 1
Pages: 5426
Publication
First Author: Zhu B
Year: 2018
Journal: Nat Commun
Title: The protective role of DOT1L in UV-induced melanomagenesis.
Volume: 9
Issue: 1
Pages: 259
Publication    
First Author: Ruiz-Vega R
Year: 2020
Journal: Elife
Title: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes.
Volume: 9
Publication
First Author: Chen S
Year: 2019
Journal: Nat Commun
Title: Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads.
Volume: 10
Issue: 1
Pages: 877
Genotype
Symbol: Cdkn2a/Cdkn2a Ctnnb1/Ctnnb1 Pten/Pten Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129/Sv * C57BL/6J * FVB * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a<+> Kras/Kras<+> Trp53/Trp53<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a Kras/Kras<+> Trp53/Trp53 Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a Trp53/Trp53 Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Kras/Kras<+> Trp53/Trp53 Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a Kras/Kras<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Braf/Braf Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Tyr-cre/ERT2)13Bos/? TgTn(sb-T2/Onc)#Dla/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox10/Sox10<+> Tg(Tyr-cre/ERT2)13Bos/? Tg(Tyr-NRAS*Q61K)1Bee/?
Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Trp53/Trp53 Tg(Tyr-cre/ERT2)13Bos/? Tg(Tyr-NRAS*Q61K)1Bee/?
Background: FVB.Cg-Tg(Tyr-cre/ERT2)13Bos Trp53 Tg(Tyr-NRAS*Q61K)1Bee
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: C3FeJ.Cg-Tg(Tyr-cre/ERT2)13Bos Gt(ROSA)26Sor/Cvrk
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a Nras/Nras Tg(Tyr-cre/ERT2)13Bos/?
Background: B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nras Cdkn2a
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a Nras/Nras Tg(Tyr-cre/ERT2)13Bos/?
Background: B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nras Cdkn2a
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a Kras/Kras<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Cdkn2a Kras
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Braf/Braf<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Braf/Braf Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Braf/Braf<+> Pten/Pten Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Braf/Braf<+> Pten/Pten Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Braf/Braf<+> Pten/Pten<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ednrb/Ednrb Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ednrb/Ednrb Tg(Dct-lacZ)#Ove/? Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mc1r/Mc1r Tg(Dct-lacZ)#Ove/? Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pikfyve/Pikfyve Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: C57BL/6 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Braf/Braf<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a Nras/Nras<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129 * 129S4/SvJae * 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: B6.Cg-Tg(Tyr-cre/ERT2)13Bos Gt(ROSA)26Sor
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Chen S
Year: 2017
Journal: Nature
Title: Palmitoylation-dependent activation of MC1R prevents melanomagenesis.
Volume: 549
Issue: 7672
Pages: 399-403
Publication
First Author: Levy C
Year: 2010
Journal: Cell
Title: Lineage-specific transcriptional regulation of DICER by MITF in melanocytes.
Volume: 141
Issue: 6
Pages: 994-1005
Publication
First Author: Sharma S
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Targeting the cyclin-dependent kinase 5 in metastatic melanoma.
Volume: 117
Issue: 14
Pages: 8001-8012
Publication
First Author: Lee EK
Year: 2013
Journal: Mol Cell Biol
Title: The FBXO4 tumor suppressor functions as a barrier to BRAFV600E-dependent metastatic melanoma.
Volume: 33
Issue: 22
Pages: 4422-33
Publication
First Author: Kwong LN
Year: 2015
Journal: J Clin Invest
Title: Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma.
Volume: 125
Issue: 4
Pages: 1459-70
Publication
First Author: Fufa TD
Year: 2015
Journal: Hum Mol Genet
Title: Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes.
Volume: 24
Issue: 19
Pages: 5433-50
Publication
First Author: Held MA
Year: 2010
Journal: Cancer Res
Title: Characterization of melanoma cells capable of propagating tumors from a single cell.
Volume: 70
Issue: 1
Pages: 388-97
Publication
First Author: Hill KS
Year: 2019
Journal: Mol Cancer Res
Title: PTPN11 Plays Oncogenic Roles and Is a Therapeutic Target for BRAF Wild-Type Melanomas.
Volume: 17
Issue: 2
Pages: 583-593
Publication
First Author: Uka R
Year: 2020
Journal: Oncogene
Title: Temporal activation of WNT/β-catenin signaling is sufficient to inhibit SOX10 expression and block melanoma growth.
Volume: 39
Issue: 20
Pages: 4132-4154
Publication
First Author: Liu W
Year: 2012
Journal: Cancer Cell
Title: LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanoma.
Volume: 21
Issue: 6
Pages: 751-64
Publication
First Author: Schaefer SM
Year: 2017
Journal: Oncogene
Title: Sox2 is dispensable for primary melanoma and metastasis formation.
Volume: 36
Issue: 31
Pages: 4516-4524
Publication  
First Author: Zingg D
Year: 2015
Journal: Nat Commun
Title: The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.
Volume: 6
Pages: 6051
Publication
First Author: Rai K
Year: 2015
Journal: Cancer Discov
Title: Dual Roles of RNF2 in Melanoma Progression.
Volume: 5
Issue: 12
Pages: 1314-27
Strain
Attribute String: mutant stock, targeted mutation, transgenic
Publication
First Author: Harris ML
Year: 2013
Journal: PLoS Genet
Title: A dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitors.
Volume: 9
Issue: 7
Pages: e1003644
Publication
First Author: Huang JL
Year: 2015
Journal: Cancer Res
Title: Oncogenic G Protein GNAQ Induces Uveal Melanoma and Intravasation in Mice.
Volume: 75
Issue: 16
Pages: 3384-97
Publication
First Author: Damsky W
Year: 2015
Journal: Cancer Cell
Title: mTORC1 activation blocks BrafV600E-induced growth arrest but is insufficient for melanoma formation.
Volume: 27
Issue: 1
Pages: 41-56
Publication
First Author: Tonks ID
Year: 2017
Journal: Oncogene
Title: Melanocyte transformation requires complete loss of all pocket protein function via a mechanism that mitigates the need for MAPK pathway activation.
Volume: 36
Issue: 26
Pages: 3789-3795
Publication
First Author: Yu Y
Year: 2018
Journal: Cancer Cell
Title: Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.
Volume: 33
Issue: 2
Pages: 322-336.e8
Strain
Attribute String: transgenic, targeted mutation, mutant strain, congenic
Publication  
First Author: Le HH
Year: 2021
Journal: EBioMedicine
Title: Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells.
Volume: 73
Pages: 103646
Publication  
First Author: Bonet C
Year: 2017
Journal: J Natl Cancer Inst
Title: Deciphering the Role of Oncogenic MITFE318K in Senescence Delay and Melanoma Progression.
Volume: 109
Issue: 8
Publication
First Author: Zhai Y
Year: 2020
Journal: Pigment Cell Melanoma Res
Title: Differences in tumor initiation and progression of melanoma in the BrafCA ;Tyr-CreERT2;Ptenf/f model between male and female mice.
Volume: 33
Issue: 1
Pages: 119-121
Publication
First Author: Zhao F
Year: 2018
Journal: Cancer Immunol Res
Title: Stromal Fibroblasts Mediate Anti-PD-1 Resistance via MMP-9 and Dictate TGFβ Inhibitor Sequencing in Melanoma.
Volume: 6
Issue: 12
Pages: 1459-1471
Publication
First Author: Chhabra G
Year: 2022
Journal: J Invest Dermatol
Title: Antimelanoma Effects of Concomitant Inhibition of SIRT1 and SIRT3 in Braf(V600E)/Pten(NULL) Mice.
Volume: 142
Issue: 4
Pages: 1145-1157.e7
Publication
First Author: Ishak Gabra MB
Year: 2020
Journal: Nat Commun
Title: Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth.
Volume: 11
Issue: 1
Pages: 3326
Publication  
First Author: RodrĆ­guez CI
Year: 2018
Journal: Cancer Lett
Title: Elevated cyclic AMP levels promote BRAFCA/Pten-/- mouse melanoma growth but pCREB is negatively correlated with human melanoma progression.
Volume: 414
Pages: 268-277
Publication
First Author: Spitzer MH
Year: 2017
Journal: Cell
Title: Systemic Immunity Is Required for Effective Cancer Immunotherapy.
Volume: 168
Issue: 3
Pages: 487-502.e15
Publication
First Author: Niu L
Year: 2024
Journal: Sci Adv
Title: Noncovalently particle-anchored cytokines with prolonged tumor retention safely elicit potent antitumor immunity.
Volume: 10
Issue: 16
Pages: eadk7695
Publication
First Author: Ferretti R
Year: 2016
Journal: Genes Dev
Title: BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistance.
Volume: 30
Issue: 1
Pages: 18-33
Publication
First Author: RodrĆ­guez CI
Year: 2017
Journal: Mol Cancer Res
Title: EPAC-RAP1 Axis-Mediated Switch in the Response of Primary and Metastatic Melanoma to Cyclic AMP.
Volume: 15
Issue: 12
Pages: 1792-1802
Publication  
First Author: Mikheil D
Year: 2023
Journal: Cancers (Basel)
Title: Notch Signaling Suppresses Melanoma Tumor Development in BRAF/Pten Mice.
Volume: 15
Issue: 2
Publication
First Author: Jahid S
Year: 2022
Journal: Cell Rep
Title: Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer.
Volume: 39
Issue: 1
Pages: 110641
Publication
First Author: Bagati A
Year: 2019
Journal: Oncogene
Title: KLF9-dependent ROS regulate melanoma progression in stage-specific manner.
Volume: 38
Issue: 19
Pages: 3585-3597
Publication  
First Author: Neubert NJ
Year: 2018
Journal: Sci Transl Med
Title: T cell-induced CSF1 promotes melanoma resistance to PD1 blockade.
Volume: 10
Issue: 436
Publication
First Author: Hanna SC
Year: 2013
Journal: J Clin Invest
Title: HIF1α and HIF2α independently activate SRC to promote melanoma metastases.
Volume: 123
Issue: 5
Pages: 2078-93
Publication
First Author: Choi YS
Year: 2022
Journal: Cell
Title: Topical therapy for regression and melanoma prevention of congenital giant nevi.
Volume: 185
Issue: 12
Pages: 2071-2085.e12
Strain
Attribute String: transgenic, targeted mutation, mutant strain, congenic
Publication
First Author: Ni TK
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Low-copy piggyBac transposon mutagenesis in mice identifies genes driving melanoma.
Volume: 110
Issue: 38
Pages: E3640-9
Publication
First Author: Vittoria MA
Year: 2022
Journal: Nat Commun
Title: Inactivation of the Hippo tumor suppressor pathway promotes melanoma.
Volume: 13
Issue: 1
Pages: 3732
Publication
First Author: Marsh Durban V
Year: 2013
Journal: J Clin Invest
Title: Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma.
Volume: 123
Issue: 12
Pages: 5104-18
Publication      
First Author: Dong B
Year: 2022
Journal: J Invest Dermatol
Title: FZD6 Promotes Melanoma Cell Invasion but Not Proliferation by Regulating Canonical Wnt Signaling and Epithelial‒Mesenchymal Transition.
Publication
First Author: Brighton HE
Year: 2018
Journal: Cancer Res
Title: New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging.
Volume: 78
Issue: 2
Pages: 542-557
Publication
First Author: Deuker MM
Year: 2015
Journal: Cancer Discov
Title: PI3'-kinase inhibition forestalls the onset of MEK1/2 inhibitor resistance in BRAF-mutated melanoma.
Volume: 5
Issue: 2
Pages: 143-53
Publication
First Author: Ho PC
Year: 2014
Journal: Cancer Res
Title: Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ.
Volume: 74
Issue: 12
Pages: 3205-17