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Search results 201 to 228 out of 228 for Tnfrsf18

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0.018s

Type

Details

Score

Publication

- | J:161428

First Author:	Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year:	2010

Title:	Annotation inferences using phylogenetic trees

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Publication

- | J:63103

First Author:	Mouse Genome Database and National Center for Biotechnology Information
Year:	2000
Journal:	Database Release
Title:	Entrez Gene Load

•

Publication

- | J:262123

First Author:	Allen Institute for Brain Science
Year:	2004
Journal:	Allen Institute
Title:	Allen Brain Atlas: mouse riboprobes

•

Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

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Publication

- | J:155721

First Author:	Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year:	2010
Journal:	Database Download
Title:	Consensus CDS project

•

Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

•

Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

•

Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

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Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

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Publication

21445534 | -

First Author:	Velavan TP
Year:	2011
Journal:	Braz J Med Biol Res
Title:	Novel regulatory SNPs in the promoter region of the TNFRSF18 gene in a Gabonese population.
Volume:	44
Issue:	5
Pages:	418-20

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Allele

Tnfrsf18<tm1(TNFRSF18)Smoc> | MGI:7292879

Name:	tumor necrosis factor receptor superfamily, member 18; targeted mutation 1, Shanghai Model Organisms Center
Allele Type:	Targeted
Attribute String:	Humanized sequence, Inserted expressed sequence

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Publication

15770698 | -

First Author:	Nocentini G
Year:	2005
Journal:	Eur J Immunol
Title:	GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily.
Volume:	35
Issue:	4
Pages:	1016-22

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Publication

22516990 | -

First Author:	Pan Y
Year:	2012
Journal:	Beijing Da Xue Xue Bao
Title:	[Effects of glucocorticoids on the expression of GTIR and apoptosis of the CD4(+)CD25(+)CD127(dim/-) T cells in patients with systemic lupus erythematosus].
Volume:	44
Issue:	2
Pages:	215-20

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Publication

22911397 | -

First Author:	Pedroza-Gonzalez A
Year:	2013
Journal:	Hepatology
Title:	Activated tumor-infiltrating CD4+ regulatory T cells restrain antitumor immunity in patients with primary or metastatic liver cancer.
Volume:	57
Issue:	1
Pages:	183-94

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Publication

23785514 | -

First Author:	Liu Y
Year:	2013
Journal:	PLoS One
Title:	Novel tumor suppressor function of glucocorticoid-induced TNF receptor GITR in multiple myeloma.
Volume:	8
Issue:	6
Pages:	e66982

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Publication

23935647 | -

First Author:	Gan X
Year:	2013
Journal:	Clin Dev Immunol
Title:	Correlation of increased blood levels of GITR and GITRL with disease severity in patients with primary Sjögren's syndrome.
Volume:	2013

Pages:	340751

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Publication

22309286 | -

First Author:	von Rahden BH
Year:	2012
Journal:	Colorectal Dis
Title:	Glucocorticoid-induced tumour necrosis factor receptor expression: a potential molecular link between steroid intake and complicated diverticulitis?
Volume:	14
Issue:	10
Pages:	1276-86

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Publication

11812990 | -

First Author:	Shimizu J
Year:	2002
Journal:	Nat Immunol
Title:	Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance.
Volume:	3
Issue:	2
Pages:	135-42

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Protein Domain

IPR034018 | TNFRSF18_N

Type:

Domain

Description:

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also known as activation-inducible TNF receptor (AITR), glucocorticoid-induced tumor necrosis factor receptor family-related protein (GITR), CD357, or GITR-D, has increased expression upon T-cell activation, and is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells []. In inflammatory cells, GITR expression indicates a possible molecular link between steroid use and complicated acute sigmoid diverticulitis; increased MMP-9 expression by GITR signaling might explain morphological changes in the colonic wall in diverticulitis []. Its ligand, GITRL, activates GITR which could then influence the activity of effector and regulatory T cells, participating in the development of several autoimmune and inflammatory diseases, including autoimmune thyroid disease and rheumatoid arthritis [, ]. In systemic lupus erythematosus (SLE) patients, serum GITRL levels are increased compared with healthy controls []. GITR and its ligand, GITRL, are possibly involved in the pathogenesis of primary Sjogren's syndrome (pSS) [].GITR is inactivated during tumor progression in Multiple Myeloma (MM); restoration of GITR expression in GITR deficient MM cells leads to inhibition of MM proliferation and induction of apoptosis, thus playing a pivotal role in MM pathogenesis and disease progression []. Regulatory T-cells (Tregs) in liver tumor up-regulate the expression of GITR compared with Tregs in tumor-free liver tissue and blood []. Regulatory single nucleotide polymorphisms (SNPs) in the promoter regions of the TNFRSF18 gene have been identified in a group of male Gabonese individuals exposed to a wide array of parasitic diseases such as malaria, filariasis and schistosomiasis, and may serve as a basis to study parasite susceptibility in association studies [].This entry represents the N-terminal domain of TNFRSF18. TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number and type of modules can vary in different members of the family [, , ].

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Protein

O35714

Organism:	Mus musculus/domesticus
Length:	228
Fragment?:	false

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Protein

Q540M6

Organism:	Mus musculus/domesticus
Length:	228
Fragment?:	false

•

Protein

B1ASL6

Organism:	Mus musculus/domesticus
Length:	314
Fragment?:	false

•

Protein

Q8C4K3

Organism:	Mus musculus/domesticus
Length:	250
Fragment?:	false

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Publication

9538693 | -

First Author:	Naismith JH
Year:	1998
Journal:	Trends Biochem Sci
Title:	Modularity in the TNF-receptor family.
Volume:	23
Issue:	2
Pages:	74-9

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Publication

11796220 | -

First Author:	Bodmer JL
Year:	2002
Journal:	Trends Biochem Sci
Title:	The molecular architecture of the TNF superfamily.
Volume:	27
Issue:	1
Pages:	19-26

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Publication

8387891 | -

First Author:	Banner DW
Year:	1993
Journal:	Cell
Title:	Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation.
Volume:	73
Issue:	3
Pages:	431-45

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