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Search results 201 to 300 out of 8113 for Trp53

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Type Details Score
Publication
37579145 | J:345289
First Author: Dibra D
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Triple-negative breast tumors are dependent on mutant p53 for growth and survival.
Volume: 120
Issue: 34
Pages: e2308807120
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Publication
20587514 | J:162466
First Author: Zhu F
Year: 2010
Journal: Cancer Res
Title: Mouse models for the p53 R72P polymorphism mimic human phenotypes.
Volume: 70
Issue: 14
Pages: 5851-9
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Publication
26399548 | J:227224
 
First Author: Lee CL
Year: 2015
Journal: Nat Commun
Title: Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma.
Volume: 6
Pages: 8477
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Publication
35320355 | J:324785
First Author: Xiong S
Year: 2022
Journal: Cancer Res
Title: Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo.
Volume: 82
Issue: 10
Pages: 1926-1936
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Publication
34515734 | J:324223
 
First Author: Sepaniac LA
Year: 2021
Journal: J Cell Biol
Title: Micronuclei in Kif18a mutant mice form stable micronuclear envelopes and do not promote tumorigenesis.
Volume: 220
Issue: 11
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Publication
11137995 | J:66733
First Author: Jackson-Grusby L
Year: 2001
Journal: Nat Genet
Title: Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation.
Volume: 27
Issue: 1
Pages: 31-9
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Publication
8846919 | J:54288
First Author: Bowman T
Year: 1996
Journal: Genes Dev
Title: Tissue-specific inactivation of p53 tumor suppression in the mouse.
Volume: 10
Issue: 7
Pages: 826-35
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Publication
35322202 | J:327070
First Author: Li Q
Year: 2022
Journal: Cell Death Differ
Title: Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development.
Volume: 29
Issue: 8
Pages: 1596-1610
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Publication
21915858 | J:180024
First Author: Camboni M
Year: 2012
Journal: J Pathol
Title: Induction of a regenerative microenvironment in skeletal muscle is sufficient to induce embryonal rhabdomyosarcoma in p53-deficient mice.
Volume: 226
Issue: 1
Pages: 40-9
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Publication
23841896 | J:331085
 
First Author: Herfindal L
Year: 2013
Journal: BMC Cancer
Title: Functional p53 is required for rapid restoration of daunorubicin-induced lesions of the spleen.
Volume: 13
Pages: 341
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Publication
30064974 | J:267091
First Author: Fink EC
Year: 2018
Journal: Blood
Title: Crbn I391V is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice.
Volume: 132
Issue: 14
Pages: 1535-1544
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Publication
15509522 | J:93631
First Author: Plummer NW
Year: 2004
Journal: Am J Pathol
Title: Loss of p53 sensitizes mice with a mutation in Ccm1 (KRIT1) to development of cerebral vascular malformations.
Volume: 165
Issue: 5
Pages: 1509-18
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Publication
30304535 | J:270064
First Author: Little JN
Year: 2019
Journal: Hum Mol Genet
Title: p53 deletion rescues lethal microcephaly in a mouse model with neural stem cell abscission defects.
Volume: 28
Issue: 3
Pages: 434-447
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Publication
18418377 | J:134785
First Author: Akala OO
Year: 2008
Journal: Nature
Title: Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors.
Volume: 453
Issue: 7192
Pages: 228-32
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Publication
25197075 | J:216364
First Author: Caprio C
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: p53 Suppression partially rescues the mutant phenotype in mouse models of DiGeorge syndrome.
Volume: 111
Issue: 37
Pages: 13385-90
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Publication
32994318 | J:297493
 
First Author: Matos-Rodrigues GE
Year: 2020
Journal: Dis Model Mech
Title: Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome.
Volume: 13
Issue: 10
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Publication
33289702 | J:305955
First Author: Castañeda-Zegarra S
Year: 2020
Journal: Aging (Albany NY)
Title: Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI.
Volume: 12
Issue: 23
Pages: 23578-23597
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Publication
23385064 | J:198324
First Author: Ma X
Year: 2013
Journal: Carcinogenesis
Title: Interaction of the oncogenic miR-21 microRNA and the p53 tumor suppressor pathway.
Volume: 34
Issue: 6
Pages: 1216-23
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Publication
21899604 | J:178012
First Author: Gil-Perotin S
Year: 2011
Journal: Eur J Neurosci
Title: Roles of p53 and p27(Kip1) in the regulation of neurogenesis in the murine adult subventricular zone.
Volume: 34
Issue: 7
Pages: 1040-52
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Publication
16260620 | J:102381
First Author: Ahkter S
Year: 2005
Journal: Mol Cell Biol
Title: Snm1-deficient mice exhibit accelerated tumorigenesis and susceptibility to infection.
Volume: 25
Issue: 22
Pages: 10071-8
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Publication
21467166 | J:171978
First Author: Yang A
Year: 2011
Journal: Cancer Res
Title: Increased survival following tumorigenesis in Ts65Dn mice that model Down syndrome.
Volume: 71
Issue: 10
Pages: 3573-81
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Publication
10191063 | J:54226
First Author: Tebbs RS
Year: 1999
Journal: Dev Biol
Title: Requirement for the Xrcc1 DNA base excision repair gene during early mouse development.
Volume: 208
Issue: 2
Pages: 513-29
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Publication
14506698 | J:85920
First Author: Schreiner B
Year: 2003
Journal: Genes Chromosomes Cancer
Title: Pattern of secondary genomic changes in pancreatic tumors of Tgf alpha/Trp53+/- transgenic mice.
Volume: 38
Issue: 3
Pages: 240-8
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Publication
28504719 | J:247823
First Author: Kawauchi D
Year: 2017
Journal: Oncogene
Title: Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells.
Volume: 36
Issue: 37
Pages: 5231-5242
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Publication
34237032 | J:310617
 
First Author: González-Martínez J
Year: 2021
Journal: JCI Insight
Title: Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias.
Volume: 6
Issue: 16
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Publication
12833065 | J:84051
First Author: Wikonkal NM
Year: 2003
Journal: Nat Cell Biol
Title: Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice.
Volume: 5
Issue: 7
Pages: 655-60
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Publication
34183771 | J:310773
First Author: Majhi PD
Year: 2021
Journal: Oncogene
Title: Genetic modifiers regulating DNA replication and double-strand break repair are associated with differences in mammary tumors in mouse models of Li-Fraumeni syndrome.
Volume: 40
Issue: 31
Pages: 5026-5037
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Publication
28714964 | J:248158
First Author: Rodriguez-Blanco J
Year: 2017
Journal: Oncogene
Title: Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma.
Volume: 36
Issue: 45
Pages: 6306-6314
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Publication
23382688 | J:195156
First Author: Watkins-Chow DE
Year: 2013
Journal: PLoS Genet
Title: Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes.
Volume: 9
Issue: 1
Pages: e1003094
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Publication
33382987 | J:307754
 
First Author: Reedich EJ
Year: 2021
Journal: Exp Neurol
Title: Spinal motor neuron loss occurs through a p53-and-p21-independent mechanism in the Smn2B/- mouse model of spinal muscular atrophy.
Volume: 337
Pages: 113587
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Publication
24788519 | J:211289
First Author: Fantauzzo KA
Year: 2014
Journal: Genes Dev
Title: PI3K-mediated PDGFRα signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways.
Volume: 28
Issue: 9
Pages: 1005-17
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Publication
28710252 | J:251326
First Author: Collin R
Year: 2017
Journal: J Immunol
Title: An Unbiased Linkage Approach Reveals That the p53 Pathway Is Coupled to NK Cell Maturation.
Volume: 199
Issue: 4
Pages: 1490-1504
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Publication
34009137 | J:308022
First Author: Flowers BM
Year: 2021
Journal: Cancer Discov
Title: Cell of Origin Influences Pancreatic Cancer Subtype.
Volume: 11
Issue: 3
Pages: 660-677
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Publication
30579708 | J:286916
 
First Author: Castañeda-Zegarra S
Year: 2019
Journal: DNA Repair (Amst)
Title: Synthetic lethality between DNA repair factors Xlf and Paxx is rescued by inactivation of Trp53.
Volume: 73
Pages: 164-169
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Publication
34601382 | J:320381
 
First Author: Prakash R
Year: 2021
Journal: DNA Repair (Amst)
Title: XRCC3 loss leads to midgestational embryonic lethality in mice.
Volume: 108
Pages: 103227
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Publication
20110418 | J:158515
First Author: Yan H
Year: 2010
Journal: Am J Pathol
Title: Pathways contributing to development of spontaneous mammary tumors in BALB/c-Trp53+/- mice.
Volume: 176
Issue: 3
Pages: 1421-32
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Publication
10749126 | J:61421
First Author: Cheo DL
Year: 2000
Journal: Cancer Res
Title: Ultraviolet B radiation-induced skin cancer in mice defective in the Xpc, Trp53, and Apex (HAP1) genes: genotype-specific effects on cancer predisposition and pathology of tumors.
Volume: 60
Issue: 6
Pages: 1580-4
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Publication
26578713 | J:235907
First Author: Hallenborg P
Year: 2016
Journal: Am J Physiol Endocrinol Metab
Title: p53 regulates expression of uncoupling protein 1 through binding and repression of PPARγ coactivator-1α.
Volume: 310
Issue: 2
Pages: E116-28
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Publication
19421407 | J:148887
First Author: Efeyan A
Year: 2009
Journal: PLoS One
Title: Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.
Volume: 4
Issue: 5
Pages: e5475
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Publication
27880895 | J:241243
First Author: McConnell AM
Year: 2016
Journal: Cell Rep
Title: p53 Regulates Progenitor Cell Quiescence and Differentiation in the Airway.
Volume: 17
Issue: 9
Pages: 2173-2182
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Publication
11417997 | J:70644
First Author: Zelazny E
Year: 2001
Journal: Exp Mol Pathol
Title: Cooperating oncogenic events in murine mammary tumorigenesis: assessment of ErbB2, mutant p53, and mouse mammary tumor virus.
Volume: 70
Issue: 3
Pages: 183-93
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Publication
10706103 | J:61217
First Author: Zhang Z
Year: 2000
Journal: Cancer Res
Title: A germ-line p53 mutation accelerates pulmonary tumorigenesis: p53-independent efficacy of chemopreventive agents green tea or dexamethasone/myo-inositol and chemotherapeutic agents taxol or adriamycin.
Volume: 60
Issue: 4
Pages: 901-7
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Publication
25088193 | J:222536
First Author: Bardot B
Year: 2015
Journal: Oncogene
Title: Mice engineered for an obligatory Mdm4 exon skipping express higher levels of the Mdm4-S isoform but exhibit increased p53 activity.
Volume: 34
Issue: 22
Pages: 2943-8
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Publication
23612969 | J:199607
First Author: Odell AF
Year: 2013
Journal: J Biol Chem
Title: A novel p53 mutant found in iatrogenic urothelial cancers is dysfunctional and can be rescued by a second-site global suppressor mutation.
Volume: 288
Issue: 23
Pages: 16704-14
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Publication
26982726 | J:232714
First Author: Liu Y
Year: 2016
Journal: Nature
Title: Deletions linked to TP53 loss drive cancer through p53-independent mechanisms.
Volume: 531
Issue: 7595
Pages: 471-475
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Publication
29479066 | J:263565
First Author: Zheng L
Year: 2018
Journal: Leukemia
Title: Utx loss causes myeloid transformation.
Volume: 32
Issue: 6
Pages: 1458-1465
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Publication
25254962 | J:222499
First Author: Hassan NM
Year: 2014
Journal: PLoS One
Title: Brm inhibits the proliferative response of keratinocytes and corneal epithelial cells to ultraviolet radiation-induced damage.
Volume: 9
Issue: 9
Pages: e107931
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Publication
15377654 | J:95193
First Author: Freie BW
Year: 2004
Journal: J Biol Chem
Title: A role for the Fanconi anemia C protein in maintaining the DNA damage-induced G2 checkpoint.
Volume: 279
Issue: 49
Pages: 50986-93
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Publication
23435420 | J:351451
First Author: Böhringer M
Year: 2013
Journal: Oncogene
Title: siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/- with susceptibility versus C57BL/6-Trp53+/- mice with resistance to mammary tumors.
Volume: 32
Issue: 48
Pages: 5458-70
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Publication
34391772 | J:314694
First Author: Douchi D
Year: 2021
Journal: Gastroenterology
Title: Induction of Gastric Cancer by Successive Oncogenic Activation in the Corpus.
Volume: 161
Issue: 6
Pages: 1907-1923.e26
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Publication
22708734 | J:307682
 
First Author: Loffler KA
Year: 2012
Journal: BMC Cancer
Title: Menin and p53 have non-synergistic effects on tumorigenesis in mice.
Volume: 12
Pages: 252
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Publication
10757812 | J:61567
First Author: Lombard DB
Year: 2000
Journal: Mol Cell Biol
Title: Mutations in the WRN gene in mice accelerate mortality in a p53-null background.
Volume: 20
Issue: 9
Pages: 3286-91
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Publication
22621437 | J:214714
First Author: Wang H
Year: 2012
Journal: Aging Cell
Title: Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated aging.
Volume: 11
Issue: 4
Pages: 704-13
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Publication
22815056 | J:263530
First Author: Wang G
Year: 2012
Journal: Birth Defects Res A Clin Mol Teratol
Title: Mutations in Lyar and p53 are synergistically lethal in female mice.
Volume: 94
Issue: 9
Pages: 729-37
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Protein Coding Gene
MGI:1913876 | Cdip1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
21317887 | J:170904
First Author: Schramek D
Year: 2011
Journal: Nat Genet
Title: The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression.
Volume: 43
Issue: 3
Pages: 212-9
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Publication
25985365 | J:314874
First Author: Belgardt BF
Year: 2015
Journal: Nat Med
Title: The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes.
Volume: 21
Issue: 6
Pages: 619-27
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Publication
16397217 | J:105038
First Author: Reilly KM
Year: 2006
Journal: Cancer Res
Title: An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model.
Volume: 66
Issue: 1
Pages: 62-8
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Publication
15289317 | J:91874
First Author: Blackburn AC
Year: 2004
Journal: Cancer Res
Title: Loss of heterozygosity occurs via mitotic recombination in Trp53+/- mice and associates with mammary tumor susceptibility of the BALB/c strain.
Volume: 64
Issue: 15
Pages: 5140-7
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Publication
10786799 | J:61973
First Author: Gao Y
Year: 2000
Journal: Nature
Title: Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development.
Volume: 404
Issue: 6780
Pages: 897-900
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Publication
16757976 | J:109354
First Author: Chao C
Year: 2006
Journal: EMBO J
Title: Ser18 and 23 phosphorylation is required for p53-dependent apoptosis and tumor suppression.
Volume: 25
Issue: 11
Pages: 2615-22
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Publication
34610416 | J:314038
 
First Author: Kanagasabai T
Year: 2021
Journal: Cancer Lett
Title: MicroRNA-21 deficiency suppresses prostate cancer progression through downregulation of the IRS1-SREBP-1 signaling pathway.
Volume: 525
Pages: 46-54
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Publication
16007165 | J:101759
First Author: Casanovas O
Year: 2005
Journal: Oncogene
Title: Incomplete inhibition of the Rb tumor suppressor pathway in the context of inactivated p53 is sufficient for pancreatic islet tumorigenesis.
Volume: 24
Issue: 44
Pages: 6597-604
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Publication
31433989 | J:285688
First Author: Di Mitri D
Year: 2019
Journal: Cell Rep
Title: Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer.
Volume: 28
Issue: 8
Pages: 2156-2168.e5
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Publication
32066953 | J:292988
First Author: Wang H
Year: 2020
Journal: Nat Immunol
Title: CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors.
Volume: 21
Issue: 3
Pages: 298-308
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Publication
30220967 | J:335866
First Author: Wu SC
Year: 2018
Journal: Oncotarget
Title: Chromatin remodeling protein HELLS is upregulated by inactivation of the RB-E2F pathway and is nonessential for osteosarcoma tumorigenesis.
Volume: 9
Issue: 66
Pages: 32580-32592
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Publication
26659571 | J:234128
First Author: Chen Y
Year: 2015
Journal: Sci Transl Med
Title: RANKL blockade prevents and treats aggressive osteosarcomas.
Volume: 7
Issue: 317
Pages: 317ra197
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Publication
22611036 | J:187012
First Author: Singh M
Year: 2012
Journal: J Pathol
Title: Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models.
Volume: 227
Issue: 4
Pages: 417-30
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Publication
12096340 | J:77982
First Author: Vooijs M
Year: 2002
Journal: Oncogene
Title: Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells.
Volume: 21
Issue: 30
Pages: 4635-45
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Publication
10783170 | J:61961
First Author: Marino S
Year: 2000
Journal: Genes Dev
Title: Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum.
Volume: 14
Issue: 8
Pages: 994-1004
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Publication
20676140 | J:165292
First Author: Cheng L
Year: 2010
Journal: Oncogene
Title: Rb inactivation accelerates neoplastic growth and substitutes for recurrent amplification of cIAP1, cIAP2 and Yap1 in sporadic mammary carcinoma associated with p53 deficiency.
Volume: 29
Issue: 42
Pages: 5700-11
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Publication
12810584 | J:83783
First Author: Marino S
Year: 2003
Journal: Development
Title: Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence.
Volume: 130
Issue: 15
Pages: 3359-68
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Publication
32591410 | J:296309
First Author: Yamauchi Y
Year: 2020
Journal: Cancer Res
Title: Rb and p53 Execute Distinct Roles in the Development of Pancreatic Neuroendocrine Tumors.
Volume: 80
Issue: 17
Pages: 3620-3630
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Publication
12839925 | J:84345
First Author: Flesken-Nikitin A
Year: 2003
Journal: Cancer Res
Title: Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium.
Volume: 63
Issue: 13
Pages: 3459-63
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Publication
17553900 | J:122263
First Author: Zhou Z
Year: 2007
Journal: Cancer Res
Title: Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts.
Volume: 67
Issue: 12
Pages: 5683-90
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Publication
23887970 | J:204385
First Author: Henriquez NV
Year: 2013
Journal: Cancer Res
Title: Comparative expression analysis reveals lineage relationships between human and murine gliomas and a dominance of glial signatures during tumor propagation in vitro.
Volume: 73
Issue: 18
Pages: 5834-44
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Publication
29720725 | J:264010
     
First Author: Li N
Year: 2018
Journal: Oncogene
Title: Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades.
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Publication
19927122 | J:156395
First Author: Jacques TS
Year: 2010
Journal: EMBO J
Title: Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes.
Volume: 29
Issue: 1
Pages: 222-35
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Publication
16707443 | J:109060
First Author: Shakhova O
Year: 2006
Journal: Cancer Res
Title: Lack of Rb and p53 delays cerebellar development and predisposes to large cell anaplastic medulloblastoma through amplification of N-Myc and Ptch2.
Volume: 66
Issue: 10
Pages: 5190-200
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Publication
24910389 | J:316436
First Author: Xie Y
Year: 2014
Journal: Mol Oncol
Title: Slug regulates E-cadherin repression via p19Arf in prostate tumorigenesis.
Volume: 8
Issue: 7
Pages: 1355-64
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Publication
27356744 | J:264783
First Author: Xie Y
Year: 2016
Journal: Oncotarget
Title: MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo.
Volume: 7
Issue: 30
Pages: 47609-47619
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Publication
19690330 | J:260259
First Author: Chen Z
Year: 2009
Journal: Sci Signal
Title: Differential p53-independent outcomes of p19(Arf) loss in oncogenesis.
Volume: 2
Issue: 84
Pages: ra44
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Publication
29185453 | J:255776
First Author: Xie Y
Year: 2017
Journal: Sci Rep
Title: Dysregulation of YAP by ARF Stimulated with Tea-derived Carbon Nanodots.
Volume: 7
Issue: 1
Pages: 16577
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Publication
25995385 | J:225608
First Author: Dorr C
Year: 2015
Journal: Mol Cancer Res
Title: Transposon Mutagenesis Screen Identifies Potential Lung Cancer Drivers and CUL3 as a Tumor Suppressor.
Volume: 13
Issue: 8
Pages: 1238-47
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Publication
29784854 | J:264280
First Author: Saito R
Year: 2018
Journal: Cancer Res
Title: Molecular Subtype-Specific Immunocompetent Models of High-Grade Urothelial Carcinoma Reveal Differential Neoantigen Expression and Response to Immunotherapy.
Volume: 78
Issue: 14
Pages: 3954-3968
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Publication
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