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Search results 201 to 250 out of 250 for Trpc7

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Details

Score

Publication

27979597 | J:315425

First Author:	Wu YL
Year:	2017
Journal:	Kidney Int
Title:	Inhibition of TRPC6 channels ameliorates renal fibrosis and contributes to renal protection by soluble klotho.
Volume:	91
Issue:	4
Pages:	830-841

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Publication

36460692 | J:334628

First Author:	Tang N
Year:	2022
Journal:	Nat Commun
Title:	TRPC channels blockade abolishes endotoxemic cardiac dysfunction by hampering intracellular inflammation and Ca(2+) leakage.
Volume:	13
Issue:	1
Pages:	7455

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Publication

28636132 | J:244477

First Author:	Belkacemi T
Year:	2017
Journal:	Glia
Title:	TRPC1- and TRPC3-dependent Ca²⁺ signaling in mouse cortical astrocytes affects injury-evoked astrogliosis in vivo.
Volume:	65
Issue:	9
Pages:	1535-1549

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Publication

22206677 | J:180287

First Author:	Paez Espinosa EV
Year:	2012
Journal:	Biochem Biophys Res Commun
Title:	Mouse transient receptor potential channel 6: role in hemostasis and thrombogenesis.
Volume:	417
Issue:	2
Pages:	853-6

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Publication

22724068 | J:311177

First Author:	Quick K
Year:	2012
Journal:	Open Biol
Title:	TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells.
Volume:	2
Issue:	5
Pages:	120068

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Publication

23800468 | J:259997

First Author:	Harper MT
Year:	2013
Journal:	Sci Signal
Title:	Transient receptor potential channels function as a coincidence signal detector mediating phosphatidylserine exposure.
Volume:	6
Issue:	281
Pages:	ra50

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Publication

36940798 | J:349842

First Author:	May CJ
Year:	2023
Journal:	Kidney Int
Title:	Podocyte protease activated receptor 1 stimulation in mice produces focal segmental glomerulosclerosis mirroring human disease signaling events.
Volume:	104
Issue:	2
Pages:	265-278

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Publication

38528525 | J:346625

First Author:	Abcouwer SF
Year:	2024
Journal:	J Neuroinflammation
Title:	The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachment.
Volume:	21
Issue:	1
Pages:	74

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Publication

35749414 | J:334958

First Author:	Boekell KL
Year:	2022
Journal:	PLoS One
Title:	Trpc6 gain-of-function disease mutation enhances phosphatidylserine exposure in murine platelets.
Volume:	17
Issue:	6
Pages:	e0270431

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Publication

35537100 | J:325671

First Author:	Wang Z
Year:	2022
Journal:	Am J Physiol Regul Integr Comp Physiol
Title:	Transient receptor potential cation channel 6 deficiency leads to increased body weight and metabolic dysfunction.
Volume:	323
Issue:	1
Pages:	R81-R97

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Publication

26392222 | J:229037

First Author:	Weber EW
Year:	2015
Journal:	J Exp Med
Title:	TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response.
Volume:	212
Issue:	11
Pages:	1883-99

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Publication

36569761 | J:332647

First Author:	Malkmus K
Year:	2022
Journal:	Front Physiol
Title:	Deletion of classical transient receptor potential 1, 3 and 6 alters pulmonary vasoconstriction in chronic hypoxia-induced pulmonary hypertension in mice.
Volume:	13

Pages:	1080875

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Publication

31162976 | J:294014

First Author:	Numaga-Tomita T
Year:	2019
Journal:	FASEB J
Title:	TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential-dependent coupling with PTEN.
Volume:	33
Issue:	9
Pages:	9785-9796

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Publication

28646178 | J:271483

First Author:	Li W
Year:	2017
Journal:	Sci Rep
Title:	Increased glomerular filtration rate and impaired contractile function of mesangial cells in TRPC6 knockout mice.
Volume:	7
Issue:	1
Pages:	4145

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Publication

30779919 | J:277912

First Author:	Chen QZ
Year:	2019
Journal:	Exp Cell Res
Title:	TRPC6 modulates adhesion of neutrophils to airway epithelial cells via NF-κB activation and ICAM-1 expression with ozone exposure.
Volume:	377
Issue:	1-2
Pages:	56-66

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Publication

25844902 | J:222410

First Author:	Wang L
Year:	2015
Journal:	J Clin Invest
Title:	Gq signaling causes glomerular injury by activating TRPC6.
Volume:	125
Issue:	5
Pages:	1913-26

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Publication

32412783 | J:298157

First Author:	Nemeth Z
Year:	2020
Journal:	Am J Physiol Heart Circ Physiol
Title:	Pressure-induced constriction of the middle cerebral artery is abolished in TrpC6 knockout mice.
Volume:	319
Issue:	1
Pages:	H42-H50

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Publication

21768109 | J:176613

First Author:	Ding Y
Year:	2011
Journal:	J Biol Chem
Title:	Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone.
Volume:	286
Issue:	36
Pages:	31799-809

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Publication

34866402 | J:345068

First Author:	Wang Z
Year:	2022
Journal:	Am J Physiol Renal Physiol
Title:	Transient receptor potential cation channel 6 contributes to kidney injury induced by diabetes and hypertension.
Volume:	322
Issue:	1
Pages:	F76-F88

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Publication

34230483 | J:313723

First Author:	Torres-Torrelo H
Year:	2021
Journal:	Nat Commun
Title:	Lactate sensing mechanisms in arterial chemoreceptor cells.
Volume:	12
Issue:	1
Pages:	4166

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Publication

23489970 | J:316060

First Author:	Medic N
Year:	2013
Journal:	Cell Calcium
Title:	Knockout of the Trpc1 gene reveals that TRPC1 can promote recovery from anaphylaxis by negatively regulating mast cell TNF-α production.
Volume:	53
Issue:	5-6
Pages:	315-26

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Publication

36224261 | J:350158

First Author:	El Hamdaoui Y
Year:	2022
Journal:	Mol Psychiatry
Title:	Analysis of hyperforin (St. John's wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugs.
Volume:	27
Issue:	12
Pages:	5070-5085

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Publication

39625977 | J:360700

First Author:	Matsushita Y
Year:	2024
Journal:	Proc Natl Acad Sci U S A
Title:	TRPC6 is a mechanosensitive channel essential for ultrasound neuromodulation in the mammalian brain.
Volume:	121
Issue:	50
Pages:	e2404877121

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Publication

31099508 | J:289230

First Author:	Kong W
Year:	2019
Journal:	Cell Physiol Biochem
Title:	Renal Fibrosis, Immune Cell Infiltration and Changes of TRPC Channel Expression after Unilateral Ureteral Obstruction in Trpc6-/- Mice.
Volume:	52
Issue:	6
Pages:	1484-1502

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Publication

32321939 | J:298507

First Author:	Bendiks L
Year:	2020
Journal:	Sci Rep
Title:	Store-operated Ca²⁺ entry in primary murine lung fibroblasts is independent of classical transient receptor potential (TRPC) channels and contributes to cell migration.
Volume:	10
Issue:	1
Pages:	6812

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Publication

23636057 | J:204765

First Author:	Lindemann O
Year:	2013
Journal:	J Immunol
Title:	TRPC6 regulates CXCR2-mediated chemotaxis of murine neutrophils.
Volume:	190
Issue:	11
Pages:	5496-505

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Publication

24453217 | J:206567

First Author:	Seo K
Year:	2014
Journal:	Proc Natl Acad Sci U S A
Title:	Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy.
Volume:	111
Issue:	4
Pages:	1551-6

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Publication

28790356 | J:275284

First Author:	Oda S
Year:	2017
Journal:	Sci Rep
Title:	TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice.
Volume:	7
Issue:	1
Pages:	7511

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Publication

30873821 | J:291784

First Author:	Hasna J
Year:	2019
Journal:	Cell Physiol Biochem
Title:	The Deletion of TRPC6 Channels Perturbs Iron and Zinc Homeostasis and Pregnancy Outcome in Mice.
Volume:	52
Issue:	3
Pages:	455-467

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Publication

27932059 | J:254041

First Author:	Hofmann K
Year:	2017
Journal:	Biochim Biophys Acta
Title:	Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis.
Volume:	1863
Issue:	2
Pages:	560-568

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Publication

29793963 | J:290103

First Author:	Ilatovskaya DV
Year:	2018
Journal:	J Am Soc Nephrol
Title:	A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease.
Volume:	29
Issue:	7
Pages:	1917-1927

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Publication

23022034 | J:189077

First Author:	Davis J
Year:	2012
Journal:	Dev Cell
Title:	A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo.
Volume:	23
Issue:	4
Pages:	705-15

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Publication

24144647 | J:281915

First Author:	Xia Y
Year:	2014
Journal:	Hypertension
Title:	Classical transient receptor potential 1 and 6 contribute to hypoxic pulmonary hypertension through differential regulation of pulmonary vascular functions.
Volume:	63
Issue:	1
Pages:	173-80

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Publication

24520961 | J:330461

First Author:	Chen W
Year:	2014
Journal:	J Thromb Haemost
Title:	Orai1-induced store-operated Ca(2+) entry enhances phospholipase activity and modulates canonical transient receptor potential channel 6 function in murine platelets.
Volume:	12
Issue:	4
Pages:	528-39

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Publication

35194063 | J:322550

First Author:	Zheng Z
Year:	2022
Journal:	Sci Rep
Title:	Role of TRPC6 in kidney damage after acute ischemic kidney injury.
Volume:	12
Issue:	1
Pages:	3038

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Publication

22176814 | J:330460

First Author:	Ramanathan G
Year:	2012
Journal:	J Thromb Haemost
Title:	Defective diacylglycerol-induced Ca2+ entry but normal agonist-induced activation responses in TRPC6-deficient mouse platelets.
Volume:	10
Issue:	3
Pages:	419-29

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Genotype

Symbol:	Trpc6/Trpc6
Background:	involves: 129S/SvEv * C57BL/6J
Zygosity:	hm
Has Mutant Allele:	true

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Genotype

Symbol:	Trpc1/Trpc1 Trpc4/Trpc4 Trpc6/Trpc6
Background:	involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Trpc6/Trpc6
Background:	involves: 129S/SvEv
Zygosity:	hm
Has Mutant Allele:	true

•

Publication

23233529 | J:259224

First Author:	Suresh Babu S
Year:	2012
Journal:	Sci Signal
Title:	Mechanism of stretch-induced activation of the mechanotransducer zyxin in vascular cells.
Volume:	5
Issue:	254
Pages:	ra91

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Publication

23832809 | J:219324

First Author:	Loga F
Year:	2013
Journal:	Cardiovasc Res
Title:	The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone.
Volume:	100
Issue:	2
Pages:	280-7

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Publication

26391658 | J:227549

First Author:	Gopal S
Year:	2015
Journal:	J Cell Biol
Title:	Transmembrane proteoglycans control stretch-activated channels to set cytosolic calcium levels.
Volume:	210
Issue:	7
Pages:	1199-211

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Publication

34764278 | J:322041

First Author:	Kim JH
Year:	2021
Journal:	Nat Commun
Title:	Insulin-activated store-operated Ca²⁺ entry via Orai1 induces podocyte actin remodeling and causes proteinuria.
Volume:	12
Issue:	1
Pages:	6537

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Publication

31961827 | J:297228

First Author:	Ortiz-Muñoz G
Year:	2020
Journal:	J Clin Invest
Title:	Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation.
Volume:	130
Issue:	4
Pages:	2041-2053

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Publication

24838176 | J:247236

First Author:	Schleifenbaum J
Year:	2014
Journal:	Circ Res
Title:	Stretch-activation of angiotensin II type 1a receptors contributes to the myogenic response of mouse mesenteric and renal arteries.
Volume:	115
Issue:	2
Pages:	263-72

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Publication

10903843 | J:63607

First Author:	Enklaar T
Year:	2000
Journal:	Genomics
Title:	Mtr1, a novel biallelically expressed gene in the center of the mouse distal chromosome 7 imprinting cluster, is a member of the Trp gene family.
Volume:	67
Issue:	2
Pages:	179-87

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Publication

16407161 | J:248210

First Author:	Kawasaki BT
Year:	2006
Journal:	Proc Natl Acad Sci U S A
Title:	Role of Src in C3 transient receptor potential channel function and evidence for a heterogeneous makeup of receptor- and store-operated Ca2+ entry channels.
Volume:	103
Issue:	2
Pages:	335-40

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Publication

19812035 | J:314377

First Author:	Miyagi K
Year:	2009
Journal:	J Biol Chem
Title:	A pathogenic C terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7.
Volume:	284
Issue:	49
Pages:	34400-12

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Publication

26604306 | J:228125

First Author:	Riazanski V
Year:	2015
Journal:	Proc Natl Acad Sci U S A
Title:	TRPC6 channel translocation into phagosomal membrane augments phagosomal function.
Volume:	112
Issue:	47
Pages:	E6486-95

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Publication

32850844 | J:309869

First Author:	Rønning SB
Year:	2020
Journal:	Front Cell Dev Biol
Title:	Syndecan-4^-/- Mice Have Smaller Muscle Fibers, Increased Akt/mTOR/S6K1 and Notch/HES-1 Pathways, and Alterations in Extracellular Matrix Components.
Volume:	8

Pages:	730

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