Type |
Details |
Score |
Publication |
First Author: |
European Mouse Mutant Archive |
Year: |
2003 |
Journal: |
Unpublished |
Title: |
Information obtained from the European Mouse Mutant Archive (EMMA) |
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•
•
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•
•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2016 |
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Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
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•
•
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•
•
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Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
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•
•
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•
•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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•
•
•
•
•
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Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
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•
•
•
•
•
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Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
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•
•
•
•
•
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Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
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•
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•
•
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Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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•
•
•
•
•
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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|
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•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
•
•
•
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
•
•
•
•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
•
•
•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
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|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
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•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
245
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Kala M |
Year: |
2005 |
Journal: |
Immunology |
Title: |
Cathepsin S is not crucial to TSHR processing and presentation in a murine model of Graves' disease. |
Volume: |
116 |
Issue: |
4 |
Pages: |
532-40 |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Allele |
Name: |
thyroid stimulating hormone receptor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Publication |
First Author: |
Rapoport B |
Year: |
2015 |
Journal: |
J Immunol |
Title: |
A unique mouse strain that develops spontaneous, iodine-accelerated, pathogenic antibodies to the human thyrotrophin receptor. |
Volume: |
194 |
Issue: |
9 |
Pages: |
4154-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
McLachlan SM |
Year: |
2019 |
Journal: |
J Immunol |
Title: |
Nanoparticles Bearing TSH Receptor Protein and a Tolerogenic Molecule Do Not Induce Immune Tolerance but Exacerbate Thyroid Autoimmunity in hTSHR/NOD.H2h4 Mice. |
Volume: |
202 |
Issue: |
9 |
Pages: |
2570-2577 |
|
•
•
•
•
•
|
Publication |
First Author: |
McLachlan SM |
Year: |
2007 |
Journal: |
Endocrinology |
Title: |
The link between Graves' disease and Hashimoto's thyroiditis: a role for regulatory T cells. |
Volume: |
148 |
Issue: |
12 |
Pages: |
5724-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
McLachlan SM |
Year: |
2017 |
Journal: |
Endocrinology |
Title: |
Variable Effects of Dietary Selenium in Mice That Spontaneously Develop a Spectrum of Thyroid Autoantibodies. |
Volume: |
158 |
Issue: |
11 |
Pages: |
3754-3764 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mizutori Y |
Year: |
2008 |
Journal: |
Clin Exp Immunol |
Title: |
Role of the transgenic human thyrotropin receptor A-subunit in thyroiditis induced by A-subunit immunization and regulatory T cell depletion. |
Volume: |
154 |
Issue: |
3 |
Pages: |
305-15 |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 51.9, Sandra M McLachlan |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 50.6, Sandra M McLachlan |
Allele Type: |
Transgenic |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Publication |
First Author: |
Pichurin PN |
Year: |
2006 |
Journal: |
J Immunol |
Title: |
Targeted expression of the human thyrotropin receptor A-subunit to the mouse thyroid: insight into overcoming the lack of response to A-subunit adenovirus immunization. |
Volume: |
176 |
Issue: |
1 |
Pages: |
668-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
McLachlan SM |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Breaking tolerance in transgenic mice expressing the human TSH receptor A-subunit: thyroiditis, epitope spreading and adjuvant as a 'double edged sword'. |
Volume: |
7 |
Issue: |
9 |
Pages: |
e43517 |
|
•
•
•
•
•
|
Publication |
First Author: |
Misharin AV |
Year: |
2009 |
Journal: |
Endocrinology |
Title: |
Studies in mice deficient for the autoimmune regulator (Aire) and transgenic for the thyrotropin receptor reveal a role for Aire in tolerance for thyroid autoantigens. |
Volume: |
150 |
Issue: |
6 |
Pages: |
2948-56 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, transgenic, major histocompatibility congenic, congenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
transgenic, mutant strain, congenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, transgenic |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(TG-TSHR)51.9Smcl/? |
Background: |
involves: BALB/c * C57BL/6 |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Sasaki N |
Year: |
2007 |
Journal: |
Mol Endocrinol |
Title: |
A mutation in Tpst2 encoding tyrosylprotein sulfotransferase causes dwarfism associated with hypothyroidism. |
Volume: |
21 |
Issue: |
7 |
Pages: |
1713-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jansson L |
Year: |
2018 |
Journal: |
Endocrinology |
Title: |
Immunotherapy With Apitopes Blocks the Immune Response to TSH Receptor in HLA-DR Transgenic Mice. |
Volume: |
159 |
Issue: |
9 |
Pages: |
3446-3457 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okada SL |
Year: |
2006 |
Journal: |
Mol Endocrinol |
Title: |
A glycoprotein hormone expressed in corticotrophs exhibits unique binding properties on thyroid-stimulating hormone receptor. |
Volume: |
20 |
Issue: |
2 |
Pages: |
414-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dogan RN |
Year: |
2003 |
Journal: |
J Immunol |
Title: |
Absence of IL-4, and not suppression of the Th2 response, prevents development of experimental autoimmune Graves' disease. |
Volume: |
170 |
Issue: |
4 |
Pages: |
2195-204 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pichurin P |
Year: |
2003 |
Journal: |
Clin Exp Immunol |
Title: |
Thyrotrophin receptor-specific memory T cell responses require normal B cells in a murine model of Graves' disease. |
Volume: |
134 |
Issue: |
3 |
Pages: |
396-402 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seale LA |
Year: |
2021 |
Journal: |
Int J Mol Sci |
Title: |
Adaptive Thermogenesis in a Mouse Model Lacking Selenoprotein Biosynthesis in Brown Adipocytes. |
Volume: |
22 |
Issue: |
2 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Aliesky HA |
Year: |
2006 |
Journal: |
Endocrinology |
Title: |
Probing the genetic basis for thyrotropin receptor antibodies and hyperthyroidism in immunized CXB recombinant inbred mice. |
Volume: |
147 |
Issue: |
6 |
Pages: |
2789-800 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stylianou IM |
Year: |
2008 |
Journal: |
J Lipid Res |
Title: |
Differences in DBA/1J and DBA/2J reveal lipid QTL genes. |
Volume: |
49 |
Issue: |
11 |
Pages: |
2402-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wagle NM |
Year: |
1994 |
Journal: |
Autoimmunity |
Title: |
Induction of hyperthyroxinemia in BALB/C but not in several other strains of mice. |
Volume: |
18 |
Issue: |
2 |
Pages: |
103-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wagle NM |
Year: |
1995 |
Journal: |
Endocrinology |
Title: |
Thyrotropin receptor-specific antibodies in BALB/cJ mice with experimental hyperthyroxinemia show a restricted binding specificity and belong to the immunoglobulin G1 subclass. |
Volume: |
136 |
Issue: |
8 |
Pages: |
3461-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Soliman M |
Year: |
1995 |
Journal: |
J Clin Endocrinol Metab |
Title: |
Graves' disease in severe combined immunodeficient mice. |
Volume: |
80 |
Issue: |
10 |
Pages: |
2848-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nagayama Y |
Year: |
2003 |
Journal: |
J Immunol |
Title: |
Prevention of autoantibody-mediated Graves'-like hyperthyroidism in mice with IL-4, a Th2 cytokine. |
Volume: |
170 |
Issue: |
7 |
Pages: |
3522-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
McLachlan SM |
Year: |
2008 |
Journal: |
Endocrinology |
Title: |
Shared and unique susceptibility genes in a mouse model of Graves' disease determined in BXH and CXB recombinant inbred mice. |
Volume: |
149 |
Issue: |
4 |
Pages: |
2001-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Read ML |
Year: |
2011 |
Journal: |
Cancer Res |
Title: |
Proto-oncogene PBF/PTTG1IP regulates thyroid cell growth and represses radioiodide treatment. |
Volume: |
71 |
Issue: |
19 |
Pages: |
6153-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seetharamaiah GS |
Year: |
2006 |
Journal: |
Thyroid |
Title: |
Differential Susceptibility of BALB/c and BALB/cBy mice to Graves' hyperthyroidism. |
Volume: |
16 |
Issue: |
7 |
Pages: |
651-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen CR |
Year: |
2015 |
Journal: |
Mol Endocrinol |
Title: |
Crystal structure of a TSH receptor monoclonal antibody: insight into Graves' disease pathogenesis. |
Volume: |
29 |
Issue: |
1 |
Pages: |
99-107 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nagayama Y |
Year: |
2004 |
Journal: |
Clin Exp Immunol |
Title: |
TSH receptor-adenovirus-induced Graves' hyperthyroidism is attenuated in both interferon-gamma and interleukin-4 knockout mice; implications for the Th1/Th2 paradigm. |
Volume: |
138 |
Issue: |
3 |
Pages: |
417-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Land KJ |
Year: |
2006 |
Journal: |
Endocrinology |
Title: |
Differential requirement of signal transducer and activator of transcription-4 (Stat4) and Stat6 in a thyrotropin receptor-289-adenovirus-induced model of Graves' hyperthyroidism. |
Volume: |
147 |
Issue: |
1 |
Pages: |
111-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Citterio CE |
Year: |
2017 |
Journal: |
J Biol Chem |
Title: |
De novo triiodothyronine formation from thyrocytes activated by thyroid-stimulating hormone. |
Volume: |
292 |
Issue: |
37 |
Pages: |
15434-15444 |
|
•
•
•
•
•
|
Publication |
First Author: |
Song Y |
Year: |
2015 |
Journal: |
J Hepatol |
Title: |
Thyroid-stimulating hormone regulates hepatic bile acid homeostasis via SREBP-2/HNF-4α/CYP7A1 axis. |
Volume: |
62 |
Issue: |
5 |
Pages: |
1171-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
McLachlan SM |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Exceptional hyperthyroidism and a role for both major histocompatibility class I and class II genes in a murine model of Graves' disease. |
Volume: |
6 |
Issue: |
6 |
Pages: |
e21378 |
|
•
•
•
•
•
|
Publication |
First Author: |
Costagliola S |
Year: |
1994 |
Journal: |
Endocrinology |
Title: |
Recombinant thyrotropin receptor and the induction of autoimmune thyroid disease in BALB/c mice: a new animal model. |
Volume: |
135 |
Issue: |
5 |
Pages: |
2150-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2000 |
Journal: |
Genome Res |
Title: |
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. |
Volume: |
10 |
Issue: |
10 |
Pages: |
1617-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
1999 |
Journal: |
Methods Enzymol |
Title: |
High-efficiency full-length cDNA cloning. |
Volume: |
303 |
|
Pages: |
19-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shibata K |
Year: |
2000 |
Journal: |
Genome Res |
Title: |
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. |
Volume: |
10 |
Issue: |
11 |
Pages: |
1757-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Katayama S |
Year: |
2005 |
Journal: |
Science |
Title: |
Antisense transcription in the mammalian transcriptome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1564-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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•
•
•
•
•
|
Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
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•
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•
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