Type |
Details |
Score |
Publication |
First Author: |
Li Q |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Systemic autoimmunity in TAM triple knockout mice causes inflammatory brain damage and cell death. |
Volume: |
8 |
Issue: |
6 |
Pages: |
e64812 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lew ED |
Year: |
2014 |
Journal: |
Elife |
Title: |
Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities. |
Volume: |
3 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Xiong W |
Year: |
2008 |
Journal: |
Reproduction |
Title: |
Gas6 and the Tyro 3 receptor tyrosine kinase subfamily regulate the phagocytic function of Sertoli cells. |
Volume: |
135 |
Issue: |
1 |
Pages: |
77-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang J |
Year: |
2011 |
Journal: |
Stem Cells |
Title: |
Transcriptome analysis of neural progenitor cells by a genetic dual reporter strategy. |
Volume: |
29 |
Issue: |
10 |
Pages: |
1589-600 |
|
•
•
•
•
•
|
Publication |
First Author: |
Williams JC |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
Increased hematopoietic cells in the mertk-/- mouse peritoneal cavity: a result of augmented migration. |
Volume: |
184 |
Issue: |
12 |
Pages: |
6637-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sandahl M |
Year: |
2010 |
Journal: |
BMC Dev Biol |
Title: |
Epithelial cell-directed efferocytosis in the post-partum mammary gland is necessary for tissue homeostasis and future lactation. |
Volume: |
10 |
|
Pages: |
122 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deng T |
Year: |
2012 |
Journal: |
Immunology |
Title: |
Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages. |
Volume: |
135 |
Issue: |
1 |
Pages: |
40-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zagórska A |
Year: |
2014 |
Journal: |
Nat Immunol |
Title: |
Diversification of TAM receptor tyrosine kinase function. |
Volume: |
15 |
Issue: |
10 |
Pages: |
920-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Johansen JE |
Year: |
2007 |
Journal: |
Physiol Behav |
Title: |
Evidence for hypothalamic dysregulation in mouse models of anorexia as well as in humans. |
Volume: |
92 |
Issue: |
1-2 |
Pages: |
278-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Burstyn-Cohen T |
Year: |
2012 |
Journal: |
Neuron |
Title: |
Genetic dissection of TAM receptor-ligand interaction in retinal pigment epithelial cell phagocytosis. |
Volume: |
76 |
Issue: |
6 |
Pages: |
1123-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Angelillo-Scherrer A |
Year: |
2008 |
Journal: |
J Clin Invest |
Title: |
Role of Gas6 in erythropoiesis and anemia in mice. |
Volume: |
118 |
Issue: |
2 |
Pages: |
583-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsubara N |
Year: |
1996 |
Journal: |
Dev Biol |
Title: |
A receptor tyrosine kinase, Sky, and its ligand Gas 6 are expressed in gonads and support primordial germ cell growth or survival in culture. |
Volume: |
180 |
Issue: |
2 |
Pages: |
499-510 |
|
•
•
•
•
•
|
Publication |
First Author: |
Broberger C |
Year: |
1999 |
Journal: |
J Neurosci |
Title: |
Changes in neuropeptide Y receptors and pro-opiomelanocortin in the anorexia (anx/anx) mouse hypothalamus. |
Volume: |
19 |
Issue: |
16 |
Pages: |
7130-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Broberger C |
Year: |
1998 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice. |
Volume: |
95 |
Issue: |
25 |
Pages: |
15043-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Subramanian M |
Year: |
2014 |
Journal: |
J Clin Invest |
Title: |
An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo. |
Volume: |
124 |
Issue: |
3 |
Pages: |
1296-308 |
|
•
•
•
•
•
|
Publication |
First Author: |
Potluri HK |
Year: |
2022 |
Journal: |
J Immunother Cancer |
Title: |
Antitumor efficacy of (90)Y-NM600 targeted radionuclide therapy and PD-1 blockade is limited by regulatory T cells in murine prostate tumors. |
Volume: |
10 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ji R |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
TAM receptors affect adult brain neurogenesis by negative regulation of microglial cell activation. |
Volume: |
191 |
Issue: |
12 |
Pages: |
6165-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chun HS |
Year: |
2003 |
Journal: |
Neuroreport |
Title: |
Identification of genes showing differential expression in anorexia mutant mouse. |
Volume: |
14 |
Issue: |
7 |
Pages: |
1055-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lai C |
Year: |
1991 |
Journal: |
Neuron |
Title: |
An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system. |
Volume: |
6 |
Issue: |
5 |
Pages: |
691-704 |
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•
•
•
•
|
Publication |
First Author: |
Burstyn-Cohen T |
Year: |
2009 |
Journal: |
J Clin Invest |
Title: |
Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis. |
Volume: |
119 |
Issue: |
10 |
Pages: |
2942-53 |
|
•
•
•
•
•
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Publication |
First Author: |
Li N |
Year: |
2004 |
Journal: |
Hum Mol Genet |
Title: |
Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus. |
Volume: |
13 |
Issue: |
2 |
Pages: |
171-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zuberi AR |
Year: |
1998 |
Journal: |
Immunity |
Title: |
Positional cloning and molecular characterization of an immunodominant cytotoxic determinant of the mouse H3 minor histocompatibility complex. |
Volume: |
9 |
Issue: |
5 |
Pages: |
687-98 |
|
•
•
•
•
•
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Publication |
First Author: |
Zhou J |
Year: |
2018 |
Journal: |
Cell Commun Signal |
Title: |
Tyro3, Axl, and Mertk receptors differentially participate in platelet activation and thrombus formation. |
Volume: |
16 |
Issue: |
1 |
Pages: |
98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rothlin CV |
Year: |
2007 |
Journal: |
Cell |
Title: |
TAM receptors are pleiotropic inhibitors of the innate immune response. |
Volume: |
131 |
Issue: |
6 |
Pages: |
1124-36 |
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•
•
•
•
•
|
Publication |
First Author: |
Zuberi AR |
Year: |
1998 |
Journal: |
J Immunol |
Title: |
Expression screening of a yeast artificial chromosome contig refines the location of the mouse H3a minor histocompatibility antigen gene. |
Volume: |
161 |
Issue: |
2 |
Pages: |
821-8 |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Cosemans JM |
Year: |
2010 |
Journal: |
J Thromb Haemost |
Title: |
Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization. |
Volume: |
8 |
Issue: |
8 |
Pages: |
1797-808 |
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•
•
•
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•
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Publication |
First Author: |
Maltais LJ |
Year: |
1984 |
Journal: |
J Hered |
Title: |
Anorexia, a recessive mutation causing starvation in preweanling mice. |
Volume: |
75 |
Issue: |
6 |
Pages: |
468-72 |
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•
•
•
•
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Publication |
First Author: |
Schalling M |
Year: |
1999 |
Journal: |
J Intern Med |
Title: |
Genes involved in animal models of obesity and anorexia. |
Volume: |
245 |
Issue: |
6 |
Pages: |
613-9 |
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•
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•
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Publication |
First Author: |
Tole S |
Year: |
1997 |
Journal: |
Development |
Title: |
Early specification and autonomous development of cortical fields in the mouse hippocampus. |
Volume: |
124 |
Issue: |
24 |
Pages: |
4959-70 |
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•
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Publication |
First Author: |
Wilks AF |
Year: |
1989 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction. |
Volume: |
86 |
Issue: |
5 |
Pages: |
1603-7 |
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Publication |
First Author: |
Biesecker LG |
Year: |
1993 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Identification of four murine cDNAs encoding putative protein kinases from primitive embryonic stem cells differentiated in vitro. |
Volume: |
90 |
Issue: |
15 |
Pages: |
7044-8 |
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Publication |
First Author: |
Hanks SK |
Year: |
1988 |
Journal: |
Science |
Title: |
The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. |
Volume: |
241 |
Issue: |
4861 |
Pages: |
42-52 |
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Publication |
First Author: |
Salian-Mehta S |
Year: |
2014 |
Journal: |
Mol Cell Endocrinol |
Title: |
Loss of Growth arrest specific gene 6 (Gas6) results in altered GnRH neuron migration, delayed vaginal opening and sexual maturation in mice. |
Volume: |
393 |
Issue: |
1-2 |
Pages: |
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First Author: |
Fan J |
Year: |
2016 |
Journal: |
Nat Methods |
Title: |
Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis. |
Volume: |
13 |
Issue: |
3 |
Pages: |
241-4 |
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•
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•
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Allele |
Name: |
TYRO3 protein tyrosine kinase 3; targeted mutation 1, Greg Lemke |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
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•
•
•
•
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Publication |
First Author: |
Gobé C |
Year: |
2019 |
Journal: |
PLoS Genet |
Title: |
Dual role of DMXL2 in olfactory information transmission and the first wave of spermatogenesis. |
Volume: |
15 |
Issue: |
2 |
Pages: |
e1007909 |
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Publication |
First Author: |
Nicol B |
Year: |
2018 |
Journal: |
Hum Mol Genet |
Title: |
Genome-wide identification of FOXL2 binding and characterization of FOXL2 feminizing action in the fetal gonads. |
Volume: |
27 |
Issue: |
24 |
Pages: |
4273-4287 |
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Publication |
First Author: |
Sammeta N |
Year: |
2010 |
Journal: |
Mol Cell Neurosci |
Title: |
Uncx regulates proliferation of neural progenitor cells and neuronal survival in the olfactory epithelium. |
Volume: |
45 |
Issue: |
4 |
Pages: |
398-407 |
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Publication |
First Author: |
Ruiz JC |
Year: |
1994 |
Journal: |
Mech Dev |
Title: |
Identification of novel protein kinases expressed in the myocardium of the developing mouse heart. |
Volume: |
48 |
Issue: |
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First Author: |
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Year: |
2016 |
Journal: |
Nat Neurosci |
Title: |
Visceral motor neuron diversity delineates a cellular basis for nipple- and pilo-erection muscle control. |
Volume: |
19 |
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10 |
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Publication |
First Author: |
Sommers CL |
Year: |
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Journal: |
Oncogene |
Title: |
Murine txk: a protein tyrosine kinase gene regulated by T cell activation. |
Volume: |
11 |
Issue: |
2 |
Pages: |
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Publication |
First Author: |
Wen Y |
Year: |
2021 |
Journal: |
Theranostics |
Title: |
hnRNPU in Sertoli cells cooperates with WT1 and is essential for testicular development by modulating transcriptional factors Sox8/9. |
Volume: |
11 |
Issue: |
20 |
Pages: |
10030-10046 |
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First Author: |
Robinson DR |
Year: |
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Journal: |
Oncogene |
Title: |
The protein tyrosine kinase family of the human genome. |
Volume: |
19 |
Issue: |
49 |
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First Author: |
Gu Z |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. |
Volume: |
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Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
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Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
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Publication |
First Author: |
GOA curators, MGI curators |
Year: |
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Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
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First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
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Year: |
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Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
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Publication |
First Author: |
International Mouse Strain Resource |
Year: |
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Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
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UniProt Feature |
Begin: |
31 |
Description: |
Tyrosine-protein kinase receptor TYRO3 |
Type: |
chain |
End: |
880 |
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Publication |
First Author: |
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Year: |
2014 |
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Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
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Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
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Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
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Year: |
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Title: |
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Volume: |
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The Gene Ontology Consortium |
Year: |
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Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
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First Author: |
Lennon G |
Year: |
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Title: |
WashU-HHMI Mouse EST Project |
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Year: |
2024 |
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Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
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PLoS Biol |
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BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
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The Gene Ontology Consortium |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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Proc Natl Acad Sci U S A |
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Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
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UniProt-GOA |
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Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
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Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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The Jackson Laboratory Mouse Radiation Hybrid Database |
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Mouse T31 Radiation Hybrid Data Load |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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PLoS Biol |
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Allele |
Name: |
TYRO3 protein tyrosine kinase 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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Gene |
Type: |
gene |
Organism: |
frog, African clawed |
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Gene |
Type: |
gene |
Organism: |
frog, African clawed |
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Publication |
First Author: |
Chien CW |
Year: |
2016 |
Journal: |
Oncogene |
Title: |
Targeting TYRO3 inhibits epithelial-mesenchymal transition and increases drug sensitivity in colon cancer. |
Volume: |
35 |
Issue: |
45 |
Pages: |
5872-5881 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
880
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
894
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
876
 |
Fragment?: |
false |
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Publication |
First Author: |
Lan Z |
Year: |
2000 |
Journal: |
Blood |
Title: |
Transforming activity of receptor tyrosine kinase tyro3 is mediated, at least in part, by the PI3 kinase-signaling pathway. |
Volume: |
95 |
Issue: |
2 |
Pages: |
633-8 |
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Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
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Genotype |
Symbol: |
anx/anx Tg(TYRO3)1Sapc/? Tyro3/Tyro3 |
Background: |
involves: C3HeB/FeJLe * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
anx/anx Tg(Tyro3-GFP)1Sapc/? Tyro3/Tyro3 |
Background: |
involves: C3HeB/FeJLe * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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Allele |
Name: |
transgene insertion 1, Sabine Cordes |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
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Allele |
Name: |
transgene insertion 1, Sabine Cordes |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
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Interaction Experiment |
Description: |
Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration. |
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