Type |
Details |
Score |
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Liu M |
Year: |
2016 |
Journal: |
Biochem Pharmacol |
Title: |
Cadmium and arsenic override NF-κB developmental regulation of the intestinal UGT1A1 gene and control of hyperbilirubinemia. |
Volume: |
110-111 |
|
Pages: |
37-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoda E |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Isothiocyanates induce UGT1A1 in humanized UGT1 mice in a CAR dependent fashion that is highly dependent upon oxidative stress. |
Volume: |
7 |
|
Pages: |
46489 |
|
•
•
•
•
•
|
Publication |
First Author: |
Famulari ES |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Human liver stem cells express UGT1A1 and improve phenotype of immunocompromised Crigler Najjar syndrome type I mice. |
Volume: |
10 |
Issue: |
1 |
Pages: |
887 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fujiwara R |
Year: |
2012 |
Journal: |
Gastroenterology |
Title: |
Reduced expression of UGT1A1 in intestines of humanized UGT1 mice via inactivation of NF-κB leads to hyperbilirubinemia. |
Volume: |
142 |
Issue: |
1 |
Pages: |
109-118.e2 |
|
•
•
•
•
•
|
Allele |
Name: |
UDP glucuronosyltransferase 1 family, polypeptide A1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
535
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Publication |
First Author: |
Ni M |
Year: |
2007 |
Journal: |
FEBS Lett |
Title: |
ER chaperones in mammalian development and human diseases. |
Volume: |
581 |
Issue: |
19 |
Pages: |
3641-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen W |
Year: |
2008 |
Journal: |
Biochem J |
Title: |
A possible biochemical link between NADPH oxidase (Nox) 1 redox-signalling and ERp72. |
Volume: |
416 |
Issue: |
1 |
Pages: |
55-63 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents protein disulphide-isomerase A4 (also known as endoplasmic reticulum protein 72kDa or ERp-72) (), which acts as a molecular ER chaperone. ER chaperones are critical not only for quality control of proteins processed in the ER, but also for regulation of ER signalling in response to ER stress []. ERp-72 catalyses the rearrangement of -S-S- bonds in proteins. It is part a large chaperone multiprotein complex comprising CABP1, DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. ERp-72 may functionally associate with NADPH oxidase 1 (NOX1) []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Fujiwara R |
Year: |
2015 |
Journal: |
Toxicol Appl Pharmacol |
Title: |
Role of extrahepatic UDP-glucuronosyltransferase 1A1: Advances in understanding breast milk-induced neonatal hyperbilirubinemia. |
Volume: |
289 |
Issue: |
1 |
Pages: |
124-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Porro F |
Year: |
2017 |
Journal: |
EMBO Mol Med |
Title: |
Promoterless gene targeting without nucleases rescues lethality of a Crigler-Najjar syndrome mouse model. |
Volume: |
9 |
Issue: |
10 |
Pages: |
1346-1355 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yeager RL |
Year: |
2009 |
Journal: |
Toxicol Sci |
Title: |
Introducing the "TCDD-inducible AhR-Nrf2 gene battery". |
Volume: |
111 |
Issue: |
2 |
Pages: |
238-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kang HJ |
Year: |
2011 |
Journal: |
Toxicol Sci |
Title: |
Detoxification: a novel function of BRCA1 in tumor suppression? |
Volume: |
122 |
Issue: |
1 |
Pages: |
26-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen S |
Year: |
2017 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia. |
Volume: |
114 |
Issue: |
8 |
Pages: |
E1432-E1440 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen S |
Year: |
2012 |
Journal: |
Hepatology |
Title: |
Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in humanized UGT1 mice. |
Volume: |
56 |
Issue: |
2 |
Pages: |
658-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yueh MF |
Year: |
2014 |
Journal: |
J Biol Chem |
Title: |
Developmental onset of bilirubin-induced neurotoxicity involves Toll-like receptor 2-dependent signaling in humanized UDP-glucuronosyltransferase1 mice. |
Volume: |
289 |
Issue: |
8 |
Pages: |
4699-709 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fujiwara R |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Developmental hyperbilirubinemia and CNS toxicity in mice humanized with the UDP glucuronosyltransferase 1 (UGT1) locus. |
Volume: |
107 |
Issue: |
11 |
Pages: |
5024-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hinds TD Jr |
Year: |
2017 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Mice with hyperbilirubinemia due to Gilbert's syndrome polymorphism are resistant to hepatic steatosis by decreased serine 73 phosphorylation of PPARα. |
Volume: |
312 |
Issue: |
4 |
Pages: |
E244-E252 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weber AA |
Year: |
2021 |
Journal: |
Drug Metab Dispos |
Title: |
Regulation of Intestinal UDP-Glucuronosyltransferase 1A1 by the Farnesoid X Receptor Agonist Obeticholic Acid Is Controlled by Constitutive Androstane Receptor through Intestinal Maturation. |
Volume: |
49 |
Issue: |
1 |
Pages: |
12-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen S |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus. |
Volume: |
280 |
Issue: |
45 |
Pages: |
37547-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bortolussi G |
Year: |
2014 |
Journal: |
Dis Model Mech |
Title: |
Age-dependent pattern of cerebellar susceptibility to bilirubin neurotoxicity in vivo in mice. |
Volume: |
7 |
Issue: |
9 |
Pages: |
1057-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang S |
Year: |
2019 |
Journal: |
Theranostics |
Title: |
Circadian Clock Gene Bmal1 Regulates Bilirubin Detoxification: A Potential Mechanism of Feedback Control of Hyperbilirubinemia. |
Volume: |
9 |
Issue: |
18 |
Pages: |
5122-5133 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fujiwara R |
Year: |
2017 |
Journal: |
Hepatol Commun |
Title: |
Severe Neonatal Hyperbilirubinemia in Crigler-Najjar Syndrome Model Mice Can Be Reversed With Zinc Protoporphyrin. |
Volume: |
1 |
Issue: |
8 |
Pages: |
792-802 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mackenzie PI |
Year: |
1997 |
Journal: |
Pharmacogenetics |
Title: |
The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. |
Volume: |
7 |
Issue: |
4 |
Pages: |
255-69 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
638
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
641
 |
Fragment?: |
false |
|
•
•
•
•
•
|