|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 231 out of 231 for Vps33a

<< First    < Previous  |  Next >    Last >>
0.025s

Categories

Hits by Category

Hits by Strain

Type Details Score
Allele
Vps33a<Gt(RRP092)Byg> | MGI:4329203
 
Name: VPS33A CORVET/HOPS core subunit; gene trap RRP092, BayGenomics
Allele Type: Gene trapped
•
•
•
•
•
Publication
25783203 | -
First Author: Wartosch L
Year: 2015
Journal: Traffic
Title: Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes.
Volume: 16
Issue: 7
Pages: 727-42
•
•
•
•
•
Publication
23901104 | -
First Author: Graham SC
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Structural basis of Vps33A recruitment to the human HOPS complex by Vps16.
Volume: 110
Issue: 33
Pages: 13345-50
•
•
•
•
•
Strain
MGI:2161263 | STOCK + Fgf5<go> Vps33a<bf>/+ Fgf5<go> Vps33a<bf>
Attribute String: mutant stock
•
•
•
•
•
Strain
MGI:5649932 | (STOCK Hm Pgm2<b> Vps33a<bf> Gusb<b> Mdh2<a> x STOCK + Pgm2<a> + Gusb<a> Mdh2<b>)F1
Attribute String: F1 hybrid, mutant stock
•
•
•
•
•
Strain
MGI:4840001 | B6;129P2-Vps33a<Gt(RRP092)Byg>/Mmucd
Attribute String: mutant stock, gene trap
•
•
•
•
•
Allele
Vps33a<tm1e(EUCOMM)Hmgu> | MGI:5009612
Name: VPS33A CORVET/HOPS core subunit; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
•
•
•
•
•
Allele
Vps33a<em2(IMPC)Tcp> | MGI:6157271
Name: VPS33A CORVET/HOPS core subunit; endonuclease-mediated mutation 2, The Centre for Phenogenomics
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Strain
MGI:2161348 | STOCK Rw Fgf5<go> Vps33a<bf>
Attribute String: mutant stock
•
•
•
•
•
Strain
MGI:3579317 | C3H101HF1 x STOCK Kit<W-sh> Fgf5<go> Vps33a<bf>/H
Attribute String: spontaneous mutation, mutant stock, deletion, inversion
•
•
•
•
•
Strain
MGI:5650466 | (STOCK Rw Fgf5<go> Vps33a<bf>/+ Fgf5<go> Vps33a<bf> x M. spretus)F1
Attribute String: F1 hybrid, mutant stock
•
•
•
•
•
Strain
MGI:5656181 | involves: 101/H * C3H/HeH * STOCK Rw Fgf5<go> Vps33a<bf>
Attribute String: Not specified
•
•
•
•
•
Strain
MGI:5656180 | involves: STOCK Rw Fgf5<go> Vps33a<bf>
Attribute String: Not specified
•
•
•
•
•
Strain
MGI:2163576 | JGBF/LeTyJ
Attribute String: inbred strain, spontaneous mutation
•
•
•
•
•
Strain
MGI:6261468 | C57BL/6NCrl-Vps33a<em2(IMPC)Tcp>/Tcp
Attribute String: coisogenic, targeted mutation
•
•
•
•
•
Strain
MGI:6866654 | C57BL/6NCrl-Vps33a<em2(IMPC)Tcp>/TcpMmucd
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Genotype
Genotype
Symbol: Vps33a/Vps33a
Background: C57BL/6NCrl-Vps33a/Tcp
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Strain
MGI:2163891 | JGBF/LeJ
Attribute String: inbred strain, spontaneous mutation
•
•
•
•
•
Genotype
Genotype
Symbol: Vps33a/Vps33a<+>
Background: C57BL/6NCrl-Vps33a/Tcp
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Protein Domain
IPR027121 | VPS33
Type: Family
Description: Vacuolar protein sorting-associated protein 33 (Vps33) is essential for vacuolar biogenesis, maturation and function. It is involved in the sorting of vacuolar proteins from the Golgi apparatus and their targeting to the vacuole []. In worm, fly, zebrafish and mammals two homologues of yeast Vps33p have been detected (termed VPS33A and VPS33B in humans). These homologues may reflect the evolution of organelle/tissue-specific functions in multicellular organisms. It is thought that VPS33B may be required for transport to conventional lysosomes, while VPS33A is mainly involved in biogenesis of melanosomes and related lysosomal compartments [, ].
•
•
•
•
•
Publication
12868054 | -
First Author: Iwaki T
Year: 2003
Journal: Yeast
Title: Characterization of vps33+, a gene required for vacuolar biogenesis and protein sorting in Schizosaccharomyces pombe.
Volume: 20
Issue: 10
Pages: 845-55
•
•
•
•
•
Protein Domain
IPR043155 | VPS33_dom3b
Type: Homologous_superfamily
Description: Members of the Sec1 family include Sec1, Sly1, Slp1/Vps33, Vps45/Stt10 (yeast), Unc-18 (nematode), Munc-18b/muSec1, Munc-18c (mouse), Rop (Drosophila), Munc-18/n-Sec1/rbSec1A and rbSec1B (rat) [].The nSec1 polypeptide chain can be divided into three domains. The first domain, consists of a five-stranded parallel β-sheet flanked by five α-helices. The second domain, like the first one, has an α-β-alpha fold, however the β-sheet of domain 2 features five parallel strands with an additional antiparallel strand on one edge. The third domain is a large insertion between the third and fourth parallel strands of domain 2, and can be subdivided in two [].Vacuolar protein sorting-associated protein 33 (Vps33) is essential for vacuolar biogenesis, maturation and function. It is involved in the sorting of vacuolar proteins from the Golgi apparatus and their targeting to the vacuole []. In worm, fly, zebrafish and mammals two homologues of yeast Vps33p have been detected (termed VPS33A and VPS33B in humans). These homologues may reflect the evolution of organelle/tissue-specific functions in multicellular organisms. It is thought that VPS33B may be required for transport to conventional lysosomes, while VPS33A is mainly involved in biogenesis of melanosomes and related lysosomal compartments [, ].This superfamily entry represents the C-terminal region of domain 3 (called domain 3b) found in VPS33.
•
•
•
•
•
Publication
19109425 | J:159132
First Author: Zhu GD
Year: 2009
Journal: Mol Biol Cell
Title: SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery.
Volume: 20
Issue: 4
Pages: 1223-40
•
•
•
•
•
Protein
Q9D2N9
Organism: Mus musculus/domesticus
Length: 598  
Fragment?: false
•
•
•
•
•
Protein
Q80XK7
Organism: Mus musculus/domesticus
Length: 598  
Fragment?: false
•
•
•
•
•
Protein
A0A0U1RPK8
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: true
•
•
•
•
•
Protein
S4R1H4
Organism: Mus musculus/domesticus
Length: 143  
Fragment?: false
•
•
•
•
•
Protein
P59016
Organism: Mus musculus/domesticus
Length: 617  
Fragment?: false
•
•
•
•
•
Protein
Q8C076
Organism: Mus musculus/domesticus
Length: 617  
Fragment?: false
•
•
•
•
•
Publication
8769846 | J:31434
First Author: Halachmi N
Year: 1996
Journal: J Neurochem
Title: The Sec1 family: a novel family of proteins involved in synaptic transmission and general secretion.
Volume: 66
Issue: 3
Pages: 889-97
•
•
•
•
•
Publication
10746715 | -
First Author: Misura KM
Year: 2000
Journal: Nature
Title: Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex.
Volume: 404
Issue: 6776
Pages: 355-62
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom