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Search results 201 to 300 out of 602931 for Was

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Type Details Score
Publication
- | J:13626
 
First Author: Ferguson JM
Year: 1973
Journal: Mouse News Lett
Title: Stumpy
Volume: 49
Pages: 23
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Publication
23495010 | J:250041
First Author: Ritterson Lew C
Year: 2013
Journal: J Cell Biochem
Title: Aldolase sequesters WASP and affects WASP/Arp2/3-stimulated actin dynamics.
Volume: 114
Issue: 8
Pages: 1928-39
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Publication
21930784 | J:178779
First Author: Kantonen S
Year: 2011
Journal: Mol Cell Biol
Title: A novel phospholipase D2-Grb2-WASp heterotrimer regulates leukocyte phagocytosis in a two-step mechanism.
Volume: 31
Issue: 22
Pages: 4524-37
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Publication
31219639 | J:279375
First Author: Fritz KR
Year: 2019
Journal: Dev Dyn
Title: Cdc42 activation by endothelin regulates neural crest cell migration in the cardiac outflow tract.
Volume: 248
Issue: 9
Pages: 795-812
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Publication
10967094 | J:65771
First Author: Vignal E
Year: 2000
Journal: J Biol Chem
Title: Characterization of TCL, a new GTPase of the rho family related to TC10 andCcdc42.
Volume: 275
Issue: 46
Pages: 36457-64
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
8666397 | J:29221
First Author: Derry JM
Year: 1995
Journal: Genomics
Title: The mouse homolog of the Wiskott-Aldrich syndrome protein (WASP) gene is highly conserved and maps near the scurfy (sf) mutation on the X chromosome.
Volume: 29
Issue: 2
Pages: 471-7
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Publication
27069113 | J:233318
First Author: Jackson SW
Year: 2016
Journal: J Exp Med
Title: B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6.
Volume: 213
Issue: 5
Pages: 733-50
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Publication
15699074 | J:96052
First Author: Round JL
Year: 2005
Journal: J Exp Med
Title: Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells.
Volume: 201
Issue: 3
Pages: 419-30
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Publication
15169891 | J:91030
First Author: Martinez-Quiles N
Year: 2004
Journal: Mol Cell Biol
Title: Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP.
Volume: 24
Issue: 12
Pages: 5269-80
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
19144319 | J:143718
First Author: Trost M
Year: 2009
Journal: Immunity
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
Volume: 30
Issue: 1
Pages: 143-54
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Publication
10857745 | J:62168
First Author: Means GD
Year: 2000
Journal: Genomics
Title: A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation.
Volume: 65
Issue: 3
Pages: 213-23
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Publication
15102471 | J:114108
First Author: Papin J
Year: 2004
Journal: Curr Opin Biotechnol
Title: Bioinformatics and cellular signaling.
Volume: 15
Issue: 1
Pages: 78-81
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Gene
456647 | LOC456647
Type: gene
Organism: chimpanzee
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Gene
741303 | LOC741303
Type: gene
Organism: chimpanzee
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Gene
421761 | WASF1
Type: gene
Organism: chicken
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Gene
426359 | WASF2
Type: gene
Organism: chicken
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Gene
555174 | wash1
Type: gene
Organism: zebrafish
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Gene
779716 | wasf3
Type: gene
Organism: frog, western clawed
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Gene
100125121 | wasf2
Type: gene
Organism: frog, western clawed
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Publication
8643625 | -
First Author: Kolluri R
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42.
Volume: 93
Issue: 11
Pages: 5615-8
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Publication
11076964 | -
First Author: Lee WL
Year: 2000
Journal: J Cell Biol
Title: Fission yeast myosin-I, Myo1p, stimulates actin assembly by Arp2/3 complex and shares functions with WASp.
Volume: 151
Issue: 4
Pages: 789-800
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Publication
23290554 | -
First Author: Urbanek AN
Year: 2013
Journal: Curr Biol
Title: A novel actin-binding motif in Las17/WASP nucleates actin filaments independently of Arp2/3.
Volume: 23
Issue: 3
Pages: 196-203
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Protein Domain
IPR027641 | WASP
Type: Family
Description: This entry represents the Actin nucleation-promoting factor WAS (WASP). The WASP proteins signal to the cytoskeleton through the Arp2/3 complex, an actin-nucleating assembly that regulates the structure and dynamics of actin filament networks at the leading edge of the cell []. The activity of WASP can be regulated by the Rho-family GTPase, Cdc42 []. Mutations in WASP lead to the Wiskott-Aldrich syndrome, a paediatric disorder characterised by actin cytoskeletal defects in haematopoietic cells, leading clinically to thrombocytopenia, eczema and immunodeficiency [].Similar to mammalian WASP proteins, Wsp1 and Las17 also has a role in regulating actin assembly [, ]. In Saccharomyces cerevisiae, Las17 is the primary activator of Arp2/3-driven actin nucleation and is required for membrane invagination during endocytosis []. Las17 can also nucleate actin filaments independently of Arp2/3 through its polyproline domain [].WASP family members have unique N-terminal regions, followed by a central segment rich in proline, and a common C-terminal region. Their conserved C-terminal VCA domain consists of two WH2 (WASP homology 2) domains ("V"referring to either a single or multiple WH2 domains), followed by a connector domain ("C") and an acidic short extension ("A"). In the VCA region, the WH2 domain(s) bind G-actin, whereas the CA domain binds Arp2/3 complex []. Their distinct N-terminal region enables family members to activate Arp2/3 in response to differentupstream signals.
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HT Experiment
E-MTAB-6912 | Single cell RNA-sequencing of E8.5 stage embryonic neural tissue from mouse
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
E-GEOD-9812 | Transcription profiling of mouse developing retinal ganglion and amacrine cells reveals molecular heterogeneity
Series Id: GSE9812
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Gene
749983 | LOC749983
Type: gene
Organism: chimpanzee
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Gene
108708712 | wasf3.L
Type: gene
Organism: frog, African clawed
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Gene
108709524 | wasf2.S
Type: gene
Organism: frog, African clawed
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Gene
108709964 | wasf3.S
Type: gene
Organism: frog, African clawed
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Gene
733146 | wasf2.L
Type: gene
Organism: frog, African clawed
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Publication
8287470 | J:44490
First Author: Cleaver JE
Year: 1994
Journal: Cell
Title: It was a very good year for DNA repair.
Volume: 76
Issue: 1
Pages: 1-4
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Publication
38598293 | J:349712
First Author: Coulter AM
Year: 2024
Journal: Mol Biol Cell
Title: WHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane closure and cargo sequestration.
Volume: 35
Issue: 6
Pages: ar80
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Publication
15965489 | J:100105
First Author: Kawasaki K
Year: 2005
Journal: Lab Invest
Title: Helicobacter felis-induced gastritis was suppressed in mice overexpressing thioredoxin-1.
Volume: 85
Issue: 9
Pages: 1104-17
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Publication
31211512 | J:295863
First Author: Li J
Year: 2019
Journal: J Cell Mol Med
Title: Spontaneous colitis in IL-10-deficient mice was ameliorated via inhibiting glutaminase1.
Volume: 23
Issue: 8
Pages: 5632-5641
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Publication
- | J:193163
     
First Author: Cattanach BM
Year: 2013
Journal: Personal Communication through S Ball (MRC Harwell) to The Jackson Laboratory
Title: The Tp(Y)1Ct Sxr Y Chromosome was of RIII origin
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Protein Coding Gene
MGI:2142282 | Whamm
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
15890347 | J:105131
First Author: Sugino H
Year: 2005
Journal: FEBS Lett
Title: ICAM-3, a ligand for DC-SIGN, was duplicated from ICAM-1 in mammalian evolution, but was lost in the rodent genome.
Volume: 579
Issue: 13
Pages: 2901-6
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Publication
25395677 | J:218392
First Author: Stickels R
Year: 2015
Journal: Biol Reprod
Title: DAX1/NR0B1 was expressed during mammalian gonadal development and gametogenesis before it was recruited to the eutherian X chromosome.
Volume: 92
Issue: 1
Pages: 22
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Publication
28396236 | J:271874
 
First Author: Li X
Year: 2017
Journal: Clin Immunol
Title: Skin inflammation induced by lupus serum was inhibited in IL-1R deficient mice.
Volume: 180
Pages: 63-68
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Gene
415457 | WHAMM
Type: gene
Organism: chicken
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Gene
100496908 | whamm
Type: gene
Organism: frog, western clawed
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Publication
26930616 | J:261354
First Author: Greifzu F
Year: 2016
Journal: PLoS One
Title: Ocular Dominance Plasticity after Stroke Was Preserved in PSD-95 Knockout Mice.
Volume: 11
Issue: 3
Pages: e0149771
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Data Source
ENVIGO
 
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Publication
10512884 | -
First Author: Madania A
Year: 1999
Journal: Mol Biol Cell
Title: The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex.
Volume: 10
Issue: 10
Pages: 3521-38
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Publication
9616374 | J:45808
First Author: Akashi T
Year: 1998
Journal: Immunology
Title: Proliferation of CD3+ B220- single-positive normal T cells was suppressed in B-cell-deficient lpr mice.
Volume: 93
Issue: 2
Pages: 238-48
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Publication
30652497 | J:307126
First Author: Xu WJ
Year: 2019
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Inhibition of GGPPS1 attenuated LPS-induced acute lung injury and was associated with NLRP3 inflammasome suppression.
Volume: 316
Issue: 3
Pages: L567-L577
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Publication
28602864 | J:254307
 
First Author: Yang H
Year: 2017
Journal: Mol Cell Endocrinol
Title: NCKX3 was compensated by calcium transporting genes and bone resorption in a NCKX3 KO mouse model.
Volume: 454
Pages: 93-102
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Publication
28824368 | J:268808
 
First Author: Ogundele OM
Year: 2017
Journal: Front Neurosci
Title: Systemic Sympathoexcitation Was Associated with Paraventricular Hypothalamic Phosphorylation of Synaptic CaMKIIα and MAPK/ErK.
Volume: 11
Pages: 447
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Publication
- | J:25449
 
First Author: Mobraaten LE
Year: 1979
Journal: Mouse News Lett
Title: Strain name change: RIII/2J strain was outcrossed to the SEC/1ReJ strain early in the pedigree
Volume: 60
Pages: 49
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Publication
15907795 | J:110994
First Author: Yamauchi K
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Apical localization of renal K channel was not altered in mutant WNK4 transgenic mice.
Volume: 332
Issue: 3
Pages: 750-5
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Publication
37421775 | J:338855
 
First Author: Zhou J
Year: 2023
Journal: Int Immunopharmacol
Title: Heat stress-induced intestinal epithelial cells necroptosis via TLR3-TRIF-RIP3 pathway was dependent on p53.
Volume: 122
Pages: 110574
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Publication
25116321 | J:315342
 
First Author: Heuss ND
Year: 2014
Journal: J Neuroinflammation
Title: Retinal dendritic cell recruitment, but not function, was inhibited in MyD88 and TRIF deficient mice.
Volume: 11
Pages: 143
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Publication
26745679 | J:346031
First Author: Yoshimura R
Year: 2016
Journal: Biosci Biotechnol Biochem
Title: Phosphorylation of 4EBP by oral leucine administration was suppressed in the skeletal muscle of PGC-1α knockout mice.
Volume: 80
Issue: 2
Pages: 288-90
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Interaction Term
MI:0837 | pH of interaction
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Publication
19668331 | J:152475
First Author: Yau TO
Year: 2009
Journal: PLoS One
Title: Deleted in liver cancer 2 (DLC2) was dispensable for development and its deficiency did not aggravate hepatocarcinogenesis.
Volume: 4
Issue: 8
Pages: e6566
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Publication
19416870 | J:148529
First Author: Huang S
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution.
Volume: 106
Issue: 20
Pages: 8290-5
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Publication
19304755 | J:173033
First Author: Lai CB
Year: 2009
Journal: Nucleic Acids Res
Title: Creation of the two isoforms of rodent NKG2D was driven by a B1 retrotransposon insertion.
Volume: 37
Issue: 9
Pages: 3032-43
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Publication
34364289 | J:319420
 
First Author: Akbor MM
Year: 2021
Journal: Biochem Biophys Res Commun
Title: A candidate gene of Alzheimer diseases was mutated in senescence-accelerated mouse prone (SAMP) 8 mice.
Volume: 572
Pages: 112-117
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Publication
29107825 | J:318504
 
First Author: Xia J
Year: 2018
Journal: J Nutr Biochem
Title: Atrazine-induced environmental nephrosis was mitigated by lycopene via modulating nuclear xenobiotic receptors-mediated response.
Volume: 51
Pages: 80-90
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Publication
25923694 | J:235099
First Author: Li G
Year: 2015
Journal: PLoS One
Title: PPARα Protein Expression Was Increased by Four Weeks of Intermittent Hypoxic Training via AMPKα2-Dependent Manner in Mouse Skeletal Muscle.
Volume: 10
Issue: 4
Pages: e0122593
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Publication
26563351 | J:266833
First Author: Sun Y
Year: 2015
Journal: J Physiol Biochem
Title: Myeloid leukemia factor 1 interfered with Bcl-XL to promote apoptosis and its function was regulated by 14-3-3.
Volume: 71
Issue: 4
Pages: 807-21
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Publication
29728128 | J:272136
First Author: Tu X
Year: 2018
Journal: Reprod Biol Endocrinol
Title: The ovarian estrogen synthesis function was impaired in Y123F mouse and partly restored by exogenous FSH supplement.
Volume: 16
Issue: 1
Pages: 44
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Gene
108711418 | whamm.L
Type: gene
Organism: frog, African clawed
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Publication
8247536 | J:15862
First Author: Yagi T
Year: 1993
Journal: Oncogene
Title: Regional localization of Fyn in adult brain; studies with mice in which fyn gene was replaced by lacZ.
Volume: 8
Issue: 12
Pages: 3343-51
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Publication
30006294 | J:301486
 
First Author: Cho S
Year: 2018
Journal: Brain Res
Title: The recovery from transient cognitive dysfunction induced by propofol was associated with enhanced autophagic flux in normal healthy adult mice.
Volume: 1700
Pages: 99-108
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Publication
27105914 | J:235163
First Author: Zhang S
Year: 2016
Journal: Biochem Biophys Res Commun
Title: High glucose-induced Matrilin-2 expression in mouse mesangial cells was mediated by transforming growth factor beta 1 (TGF-β1).
Volume: 474
Issue: 2
Pages: 303-308
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Publication
7720411 | J:22373
First Author: Takahashi Y
Year: 1994
Journal: Chromosoma
Title: Methylation imprinting was observed of mouse mo-2 macrosatellite on the pseudoautosomal region but not on chromosome 9.
Volume: 103
Issue: 7
Pages: 450-8
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Publication
18650809 | -
First Author: Cheng HC
Year: 2008
Journal: Nature
Title: Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspF(U).
Volume: 454
Issue: 7207
Pages: 1009-13
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Publication
22847007 | -
First Author: Gaucher JF
Year: 2012
Journal: J Biol Chem
Title: Interactions of isolated C-terminal fragments of neural Wiskott-Aldrich syndrome protein (N-WASP) with actin and Arp2/3 complex.
Volume: 287
Issue: 41
Pages: 34646-59
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Protein
Q8VDD8
Organism: Mus musculus/domesticus
Length: 475  
Fragment?: false
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Pseudogene
MGI:4944175 | Cd244b
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGI:4944183 | Cd244c
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGI:4944185 | Cd244e
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGI:4944187 | Cd244f
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGI:4944202 | Cd244d
Type: pseudogene
Organism: mouse, laboratory
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Other Genome Feature
MGI:4944164 | Cd244g
Type: sequence_feature
Organism: mouse, laboratory
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HT Experiment
GSE159184 | Next-Generation Sequencing was used to conduct a quantitative analysis of Wild Type (Ctrl) and Stat3 KO (Test) long bone transcriptomes.
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
9655611 | J:85827
First Author: Shintani T
Year: 1998
Journal: Neurosci Lett
Title: Neurons as well as astrocytes express proteoglycan-type protein tyrosine phosphatase zeta/RPTPbeta: analysis of mice in which the PTPzeta/RPTPbeta gene was replaced with the LacZ gene.
Volume: 247
Issue: 2-3
Pages: 135-8
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Interaction Term
MI:0836 | temperature of interaction
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Publication
14732490 | J:77554
First Author: Kamata T
Year: 2004
Journal: Biochim Biophys Acta
Title: R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants.
Volume: 1676
Issue: 1
Pages: 51-62
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Publication
1381627 | J:2535
First Author: Tono T
Year: 1992
Journal: Blood
Title: c-kit Gene was not transcribed in cultured mast cells of mast cell-deficient Wsh/Wsh mice that have a normal number of erythrocytes and a normal c-kit coding region.
Volume: 80
Issue: 6
Pages: 1448-53
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Publication
34285285 | J:359843
First Author: Li SC
Year: 2021
Journal: Sci Rep
Title: MiR-486-3p was downregulated at microRNA profiling of adrenals of multiple endocrine neoplasia type 1 mice, and inhibited human adrenocortical carcinoma cell lines.
Volume: 11
Issue: 1
Pages: 14772
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Publication
28890385 | J:302771
 
First Author: Hanif A
Year: 2017
Journal: Prostaglandins Other Lipid Mediat
Title: Reduced coronary reactive hyperemia in mice was reversed by the soluble epoxide hydrolase inhibitor (t-AUCB): Role of adenosine A2A receptor and plasma oxylipins.
Volume: 131
Pages: 83-95
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Publication
15572149 | J:95744
First Author: Ha HY
Year: 2005
Journal: Dev Biol
Title: The axon guidance defect of the telencephalic commissures of the JSAP1-deficient brain was partially rescued by the transgenic expression of JIP1.
Volume: 277
Issue: 1
Pages: 184-99
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Gene
MGI:95973 | H26
Type: gene
Organism: mouse, laboratory
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Allele
Whamm<+> | MGI:3605744
 
Name: WAS protein homolog associated with actin, golgi membranes and microtubules; wild type
Allele Type: Not Specified
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Publication
2030914 | J:37010
First Author: Blake TJ
Year: 1991
Journal: Oncogene
Title: The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif.
Volume: 6
Issue: 4
Pages: 653-7
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Publication
23884936 | J:199795
First Author: Zamzow DR
Year: 2013
Journal: J Neurosci
Title: An increase in the association of GluN2B containing NMDA receptors with membrane scaffolding proteins was related to memory declines during aging.
Volume: 33
Issue: 30
Pages: 12300-5
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Publication
25645154 | J:220992
 
First Author: Yan WW
Year: 2015
Journal: Brain Res
Title: Long-term acarbose administration alleviating the impairment of spatial learning and memory in the SAMP8 mice was associated with alleviated reduction of insulin system and acetylated H4K8.
Volume: 1603
Pages: 22-31
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Publication
35676717 | J:361200
First Author: Hughes JF
Year: 2022
Journal: BMC Biol
Title: A gene deriving from the ancestral sex chromosomes was lost from the X and retained on the Y chromosome in eutherian mammals.
Volume: 20
Issue: 1
Pages: 133
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Publication
36408520 | J:331407
 
First Author: Nguyen PTT
Year: 2022
Journal: Front Neurol
Title: Age-related hearing loss was accelerated by apoptosis of spiral ganglion and stria vascularis cells in ApoE KO mice with hyperglycemia and hyperlipidemia.
Volume: 13
Pages: 1016654
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Publication
31410614 | J:298522
First Author: Ison JR
Year: 2019
Journal: J Assoc Res Otolaryngol
Title: Sound Localization in Preweanling Mice Was More Severely Affected by Deleting the Kcna1 Gene Compared to Deleting Kcna2, and a Curious Inverted-U Course of Development That Appeared to Exceed Adult Performance Was Observed in All Groups.
Volume: 20
Issue: 6
Pages: 565-577
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Allele
Whamm<em2Cya> | MGI:7797096
Name: WAS protein homolog associated with actin, golgi membranes and microtubules; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
10724160 | -
First Author: Kim AS
Year: 2000
Journal: Nature
Title: Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein.
Volume: 404
Issue: 6774
Pages: 151-8
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