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Search results 201 to 300 out of 373 for Xpa

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Type Details Score
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Yonemasu R
Year: 2005
Journal: DNA Repair (Amst)
Title: Disruption of mouse XAB2 gene involved in pre-mRNA splicing, transcription and transcription-coupled DNA repair results in preimplantation lethality.
Volume: 4
Issue: 4
Pages: 479-91
Protein Domain
Type: Homologous_superfamily
Description: Xeroderma pigmentosum (XP) []is a human autosomal recessive disease,characterised by a high incidence of sunlight-induced skin cancer. Skin cells of individual's with this condition are hypersensitive to ultraviolet light, dueto defects in the incision step of DNA excision repair. There are a minimum ofseven genetic complementation groups involved in this pathway: XP-A to XP-G.XP-A is the most severe form of the disease and is due to defects in a 30kDanuclear protein called XPA (or XPAC) [].The sequence of the XPA protein is conserved from higher eukaryotes []toyeast (gene RAD14) []. XPA is a hydrophilic protein of 247 to 296 amino-acidresidues which has a C4-type zinc finger motif in its central section.This superfamily represents a domain of the XPA protein.
Gene
Type: gene
Organism: frog, African clawed
DO Term
Publication
First Author: Jarrett SG
Year: 2014
Journal: Mol Cell
Title: PKA-mediated phosphorylation of ATR promotes recruitment of XPA to UV-induced DNA damage.
Volume: 54
Issue: 6
Pages: 999-1011
Publication  
First Author: Cleaver JE
Year: 1997
Journal: Biochem J
Title: The DNA damage-recognition problem in human and other eukaryotic cells: the XPA damage binding protein.
Volume: 328 ( Pt 1)
Pages: 1-12
Allele    
Name: XPA binding protein 2; wild type
Publication
First Author: Kang TH
Year: 2011
Journal: Nucleic Acids Res
Title: Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein.
Volume: 39
Issue: 8
Pages: 3176-87
Publication
First Author: Cleaver JE
Year: 1994
Journal: Somat Cell Mol Genet
Title: Mutation and expression of the XPA gene in revertants and hybrids of a xeroderma pigmentosum cell line.
Volume: 20
Issue: 4
Pages: 327-37
Protein
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: true
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Goulielmaki E
Year: 2021
Journal: Nat Commun
Title: The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing.
Volume: 12
Issue: 1
Pages: 3153
GXD Expression  
Probe: MGI:3585165
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585663
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3585165
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585663
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3585165
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585663
Age: postnatal day 6
Specimen Label: CNS
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3585165
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585663
Age: postnatal day 6
Specimen Label: CNS
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4844962
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3270519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4848751
Age: embryonic day 11.5
Note: Staining is present in the middle limb.
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3585165
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585663
Age: postnatal day 6
Specimen Label: CNS
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:3585165
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585663
Age: postnatal day 2-3
Image: P2/3
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3585165
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585663
Age: postnatal day 4-5
Image: P4/5
Note: Expression was detected in the outer neuroblastic layer but was higher in the vitreal outer neuroblastic layer.
Specimen Label: P4/5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3585165
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585663
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3585165
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585663
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3585165
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585663
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3843998
Assay Type: RNA in situ
Annotation Date: 2009-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:3844039
Age: embryonic day 10.5
Note: Expression was low in the dorsal spinal cord.
Specimen Label: Table 1
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3585165
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:3574228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585663
Age: postnatal adult
Note: Expression was detected in bipolar cells.
Specimen Label: Adult
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4844962
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1618417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4848751
Age: embryonic day 10.5
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4844962
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1618419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4848751
Age: embryonic day 11.5
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 2
Allele
Name: XPA binding protein 2; targeted mutation 1, Kiyoji Tanaka
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: XPA binding protein 2; targeted mutation 2, Kiyoji Tanaka
Allele Type: Targeted
Attribute String: Null/knockout
Publication    
First Author: Strausberg R
Year: 2002
Journal: GenBank Submission
Title: Mus musculus, similar to XPA binding protein 1; putative ATP (GTP)-binding protein, clone MGC: 27619 IMAGE: 4505118, mRNA, complete cds
Pages: BC020174
Allele
Name: XPA binding protein 2; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: XPA binding protein 2; targeted mutation 2e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: XPA binding protein 2; targeted mutation 2a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Genotype
Symbol: Xab2/Xab2
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Xab2/Xab2
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 567  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 567  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 547  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Buchko GW
Year: 1999
Journal: Biochemistry
Title: Interactions of human nucleotide excision repair protein XPA with DNA and RPA70 Delta C327: chemical shift mapping and 15N NMR relaxation studies.
Volume: 38
Issue: 46
Pages: 15116-28
Publication
First Author: Kang TH
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase.
Volume: 107
Issue: 11
Pages: 4890-5
Genotype
Symbol: Ercc2/Ercc2 Xpa/Xpa
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Allele
Name: xeroderma pigmentosum, complementation group A; targeted mutation 1, Kiyoji Tanaka
Allele Type: Targeted
Attribute String: Null/knockout
Publication
First Author: Tripsianes K
Year: 2007
Journal: Nucleic Acids Res
Title: Analysis of the XPA and ssDNA-binding surfaces on the central domain of human ERCC1 reveals evidence for subfunctionalization.
Volume: 35
Issue: 17
Pages: 5789-98
Publication
First Author: Zhang XM
Year: 2005
Journal: Invest Ophthalmol Vis Sci
Title: Transgenic mice expressing Cre-recombinase specifically in retinal rod bipolar neurons.
Volume: 46
Issue: 10
Pages: 3515-20
Genotype
Symbol: Xpa/Xpa
Background: involves: C57BL/6 * CBA
Zygosity: hm
Has Mutant Allele: true
Allele
Name: xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg
Allele Type: Targeted
Attribute String: Null/knockout
Strain
Attribute String: congenic, mutant strain, targeted mutation
Genotype
Symbol: Xpa/Xpa
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Xpa/Xpa
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Xpa/Xpa
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
Protein Domain
Type: Conserved_site
Description: Xeroderma pigmentosum (XP) []is a human autosomal recessive disease,characterised by a high incidence of sunlight-induced skin cancer. Skin cells of individual's with this condition are hypersensitive to ultraviolet light, dueto defects in the incision step of DNA excision repair. There are a minimum ofseven genetic complementation groups involved in this pathway: XP-A to XP-G.XP-A is the most severe form of the disease and is due to defects in a 30kDanuclear protein called XPA (or XPAC) [].The sequence of the XPA protein is conserved from higher eukaryotes []toyeast (gene RAD14) []. XPA is a hydrophilic protein of 247 to 296 amino-acidresidues which has a C4-type zinc finger motif in its central section.This entry contains the zinc-finger containing region in the XPA protein. It is found N-terminal to ()
Protein Domain
Type: Domain
Description: Xeroderma pigmentosum (XP) []is a human autosomal recessive disease,characterised by a high incidence of sunlight-induced skin cancer. Skin cells of individual's with this condition are hypersensitive to ultraviolet light, dueto defects in the incision step of DNA excision repair. There are a minimum ofseven genetic complementation groups involved in this pathway: XP-A to XP-G.XP-A is the most severe form of the disease and is due to defects in a 30kDanuclear protein called XPA (or XPAC) [].The sequence of the XPA protein is conserved from higher eukaryotes []toyeast (gene RAD14) []. XPA is a hydrophilic protein of 247 to 296 amino-acidresidues which has a C4-type zinc finger motif in its central section.This entry represents the uncharacterised C-terminal domain of the XPA protein.
Protein Domain
Type: Conserved_site
Description: Xeroderma pigmentosum (XP) []is a human autosomal recessive disease,characterised by a high incidence of sunlight-induced skin cancer. Skin cells of individual's with this condition are hypersensitive to ultraviolet light, dueto defects in the incision step of DNA excision repair. There are a minimum ofseven genetic complementation groups involved in this pathway: XP-A to XP-G.XP-A is the most severe form of the disease and is due to defects in a 30kDanuclear protein called XPA (or XPAC) [].The sequence of the XPA protein is conserved from higher eukaryotes []toyeast (gene RAD14) []. XPA is a hydrophilic protein of 247 to 296 amino-acidresidues which has a C4-type zinc finger motif in its central section.This entry corresponds to the second conserved site in the XPA protein. It is a highly conserved region located some 12 residues after the zinc finger region
Strain
Attribute String: congenic, mutant strain, endonuclease-mediated mutation, targeted mutation
Genotype
Symbol: Ercc2/Ercc2 Xpa/Xpa
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Trp53/Trp53<+> Xpa/Xpa
Background: involves: 129P2/OlaHsd * 129S2/SvPas
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Xpa/Xpa
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Nitta M
Year: 2000
Journal: Nucleic Acids Res
Title: A novel cytoplasmic GTPase XAB1 interacts with DNA repair protein XPA.
Volume: 28
Issue: 21
Pages: 4212-8
Protein Domain
Type: Family
Description: GPN-loop GTPase 1 (Gpn1) belongs to the GPN-loop GTPase family []. It is also known as Npa3 in budding yeasts and XAB1 in humans.Npa3 has GTPase activity that is essential for its binding to RNA polymerase II (RNAPII) and the nuclear localisation of RNAPII [].XAB1 is a cytoplasmic GTPase involved in nuclear localisation of DNA repair protein XPA []. This entry also includes archaeal GPN-loop GTPases, such as PYRAB14380 from Pyrococcus abyssi [].
Strain
Attribute String: congenic, mutant strain, targeted mutation
Genotype
Symbol: Ercc6/Ercc6 Xpa/Xpa
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ercc6/Ercc6 Xpa/Xpa
Background: B6.129P2-Xpa Ercc6
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Fishman R
Year: 2001
Journal: Acta Crystallogr D Biol Crystallogr
Title: Structure at 2.6 A resolution of phenylalanyl-tRNA synthetase complexed with phenylalanyl-adenylate in the presence of manganese.
Volume: 57
Issue: Pt 11
Pages: 1534-44
Publication
First Author: Heldwein EE
Year: 2001
Journal: Nature
Title: Crystal structure of the transcription activator BmrR bound to DNA and a drug.
Volume: 409
Issue: 6818
Pages: 378-82
Publication
First Author: de Beer T
Year: 2002
Journal: Mol Cell
Title: Insights into specific DNA recognition during the assembly of a viral genome packaging machine.
Volume: 9
Issue: 5
Pages: 981-91