| Type |
Details |
Score |
| Publication |
| First Author: |
Knauer SK |
| Year: |
2005 |
| Journal: |
Mol Cell Biol |
| Title: |
Nuclear export is evolutionarily conserved in CVC paired-like homeobox proteins and influences protein stability, transcriptional activation, and extracellular secretion. |
| Volume: |
25 |
| Issue: |
7 |
| Pages: |
2573-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gao C |
| Year: |
2006 |
| Journal: |
FEBS Lett |
| Title: |
CRM1 mediates nuclear export of HDAC7 independently of HDAC7 phosphorylation and association with 14-3-3s. |
| Volume: |
580 |
| Issue: |
21 |
| Pages: |
5096-104 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Agassandian M |
| Year: |
2012 |
| Journal: |
Mol Biol Cell |
| Title: |
Calcium-calmodulin kinase I cooperatively regulates nucleocytoplasmic shuttling of CCTα by accessing a nuclear export signal. |
| Volume: |
23 |
| Issue: |
14 |
| Pages: |
2755-69 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suárez-Sánchez R |
| Year: |
2014 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Nucleocytoplasmic shuttling of the Duchenne muscular dystrophy gene product dystrophin Dp71d is dependent on the importin α/β and CRM1 nuclear transporters and microtubule motor dynein. |
| Volume: |
1843 |
| Issue: |
5 |
| Pages: |
985-1001 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fei E |
| Year: |
2010 |
| Journal: |
J Biol Chem |
| Title: |
Nucleocytoplasmic shuttling of dysbindin-1, a schizophrenia-related protein, regulates synapsin I expression. |
| Volume: |
285 |
| Issue: |
49 |
| Pages: |
38630-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zerfaoui M |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
Poly(ADP-ribose) polymerase-1 is a determining factor in Crm1-mediated nuclear export and retention of p65 NF-kappa B upon TLR4 stimulation. |
| Volume: |
185 |
| Issue: |
3 |
| Pages: |
1894-902 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shinmura K |
| Year: |
2005 |
| Journal: |
FEBS Lett |
| Title: |
Characterization of centrosomal association of nucleophosmin/B23 linked to Crm1 activity. |
| Volume: |
579 |
| Issue: |
29 |
| Pages: |
6621-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
von Knethen A |
| Year: |
2010 |
| Journal: |
J Cell Sci |
| Title: |
Casein-kinase-II-dependent phosphorylation of PPARgamma provokes CRM1-mediated shuttling of PPARgamma from the nucleus to the cytosol. |
| Volume: |
123 |
| Issue: |
Pt 2 |
| Pages: |
192-201 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Phillips RS |
| Year: |
2002 |
| Journal: |
J Biol Chem |
| Title: |
Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling. |
| Volume: |
277 |
| Issue: |
13 |
| Pages: |
11606-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stipanovich A |
| Year: |
2008 |
| Journal: |
Nature |
| Title: |
A phosphatase cascade by which rewarding stimuli control nucleosomal response. |
| Volume: |
453 |
| Issue: |
7197 |
| Pages: |
879-84 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cong F |
| Year: |
2004 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin. |
| Volume: |
101 |
| Issue: |
9 |
| Pages: |
2882-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McKinsey TA |
| Year: |
2006 |
| Journal: |
Mol Biol Cell |
| Title: |
Class II histone deacetylases confer signal responsiveness to the ankyrin-repeat proteins ANKRA2 and RFXANK. |
| Volume: |
17 |
| Issue: |
1 |
| Pages: |
438-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Barnfield PC |
| Year: |
2005 |
| Journal: |
Differentiation |
| Title: |
Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms. |
| Volume: |
73 |
| Issue: |
8 |
| Pages: |
397-405 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Du JX |
| Year: |
2008 |
| Journal: |
J Biol Chem |
| Title: |
SUMOylation regulates nuclear localization of Krüppel-like factor 5. |
| Volume: |
283 |
| Issue: |
46 |
| Pages: |
31991-2002 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li X |
| Year: |
2020 |
| Journal: |
Cereb Cortex |
| Title: |
Inhibition of Autism-Related Crm1 Disrupts Mitosis and Induces Apoptosis of the Cortical Neural Progenitors. |
| Volume: |
30 |
| Issue: |
7 |
| Pages: |
3960-3976 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Edens BM |
| Year: |
2019 |
| Journal: |
Cell Rep |
| Title: |
FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export. |
| Volume: |
28 |
| Issue: |
4 |
| Pages: |
845-854.e5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim JY |
| Year: |
2010 |
| Journal: |
Nat Neurosci |
| Title: |
HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage. |
| Volume: |
13 |
| Issue: |
2 |
| Pages: |
180-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sakiyama H |
| Year: |
2008 |
| Journal: |
J Biol Chem |
| Title: |
Regulation of nuclear import/export of carbohydrate response element-binding protein (ChREBP): interaction of an alpha-helix of ChREBP with the 14-3-3 proteins and regulation by phosphorylation. |
| Volume: |
283 |
| Issue: |
36 |
| Pages: |
24899-908 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Eilers AL |
| Year: |
2002 |
| Journal: |
Mol Cell Biol |
| Title: |
A novel heterodimerization domain, CRM1, and 14-3-3 control subcellular localization of the MondoA-Mlx heterocomplex. |
| Volume: |
22 |
| Issue: |
24 |
| Pages: |
8514-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fernandez-L A |
| Year: |
2009 |
| Journal: |
Genes Dev |
| Title: |
YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation. |
| Volume: |
23 |
| Issue: |
23 |
| Pages: |
2729-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Samuels AL |
| Year: |
2009 |
| Journal: |
Blood |
| Title: |
Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation. |
| Volume: |
113 |
| Issue: |
16 |
| Pages: |
3845-56 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
564
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fuchs S |
| Year: |
2002 |
| Journal: |
BMC Genet |
| Title: |
Comparative transcription map of the wobbler critical region on mouse chromosome 11 and the homologous region on human chromosome 2p13-14. |
| Volume: |
3 |
|
| Pages: |
14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nagamori I |
| Year: |
2006 |
| Journal: |
J Biol Chem |
| Title: |
Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation. |
| Volume: |
281 |
| Issue: |
22 |
| Pages: |
15073-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hilditch-Maguire P |
| Year: |
2000 |
| Journal: |
Hum Mol Genet |
| Title: |
Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles. |
| Volume: |
9 |
| Issue: |
19 |
| Pages: |
2789-97 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Evsikov AV |
| Year: |
2004 |
| Journal: |
Cytogenet Genome Res |
| Title: |
Systems biology of the 2-cell mouse embryo. |
| Volume: |
105 |
| Issue: |
2-4 |
| Pages: |
240-50 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Cai Y |
| Year: |
2015 |
| Journal: |
BMC Pulm Med |
| Title: |
Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice. |
| Volume: |
15 |
|
| Pages: |
72 |
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•
•
•
•
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| Publication |
| First Author: |
Svärd J |
| Year: |
2006 |
| Journal: |
Dev Cell |
| Title: |
Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway. |
| Volume: |
10 |
| Issue: |
2 |
| Pages: |
187-97 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Maggi LB Jr |
| Year: |
2008 |
| Journal: |
Mol Cell Biol |
| Title: |
Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome. |
| Volume: |
28 |
| Issue: |
23 |
| Pages: |
7050-65 |
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•
•
•
•
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| Publication |
| First Author: |
Moon S |
| Year: |
2018 |
| Journal: |
Cell Death Dis |
| Title: |
Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis. |
| Volume: |
9 |
| Issue: |
11 |
| Pages: |
1118 |
|
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•
•
•
•
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| First Author: |
Zhou J |
| Year: |
2017 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. |
| Volume: |
1860 |
| Issue: |
12 |
| Pages: |
1159-1168 |
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•
•
•
•
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| First Author: |
Lo JC |
| Year: |
2012 |
| Journal: |
PLoS Genet |
| Title: |
RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. |
| Volume: |
8 |
| Issue: |
10 |
| Pages: |
e1002969 |
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•
•
•
•
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| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
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•
•
•
•
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| First Author: |
Centre for Modeling Human Disease |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the NorCOMM project by the Centre for Modeling Human Disease (Cmhd), Institute of Biomaterials & Biomedical Engineering, University of Toronto |
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•
•
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| First Author: |
Shanghai Model Organisms Center |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
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•
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| First Author: |
MGI and IMPC |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2001 |
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| Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
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Hansen J |
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2003 |
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Proc Natl Acad Sci U S A |
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A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
| Volume: |
100 |
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Friedel RH |
| Year: |
2007 |
| Journal: |
Brief Funct Genomic Proteomic |
| Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
| Volume: |
6 |
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3 |
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180-5 |
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Mouse Genome Informatics Scientific Curators |
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2002 |
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Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
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Nucleic Acids Res |
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GenePaint.org: an atlas of gene expression patterns in the mouse embryo. |
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Nucleic Acids Res |
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BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
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2021 |
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Front Mol Neurosci |
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Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
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Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
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UniProt-GOA |
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•
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| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
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•
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•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
564
 |
| Fragment?: |
false |
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•
•
•
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| Allele |
| Name: |
exportin 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Conditional ready, No functional change |
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•
•
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| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
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•
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| Publication |
| First Author: |
Kim WK |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
Androgen deprivation induces double-null prostate cancer via aberrant nuclear export and ribosomal biogenesis through HGF and Wnt activation. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
1231 |
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•
•
•
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| Publication |
| First Author: |
Brunetti L |
| Year: |
2018 |
| Journal: |
Cancer Cell |
| Title: |
Mutant NPM1 Maintains the Leukemic State through HOX Expression. |
| Volume: |
34 |
| Issue: |
3 |
| Pages: |
499-512.e9 |
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•
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•
•
•
|
| Publication |
| First Author: |
Tan M |
| Year: |
2014 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
Novel inhibitors of nuclear transport cause cell cycle arrest and decrease cyst growth in ADPKD associated with decreased CDK4 levels. |
| Volume: |
307 |
| Issue: |
11 |
| Pages: |
F1179-86 |
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•
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•
•
•
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| Publication |
| First Author: |
Chaudhry S |
| Year: |
2024 |
| Journal: |
Leukemia |
| Title: |
Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition. |
| Volume: |
38 |
| Issue: |
9 |
| Pages: |
1894-1905 |
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•
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•
•
•
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| Publication |
| First Author: |
Schmidt J |
| Year: |
2013 |
| Journal: |
Leukemia |
| Title: |
Genome-wide studies in multiple myeloma identify XPO1/CRM1 as a critical target validated using the selective nuclear export inhibitor KPT-276. |
| Volume: |
27 |
| Issue: |
12 |
| Pages: |
2357-65 |
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•
•
•
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| Publication |
| First Author: |
Hing ZA |
| Year: |
2015 |
| Journal: |
Blood |
| Title: |
Selinexor is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia. |
| Volume: |
125 |
| Issue: |
20 |
| Pages: |
3128-32 |
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•
•
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| Publication |
| First Author: |
Machlus KR |
| Year: |
2017 |
| Journal: |
Blood |
| Title: |
Selinexor-induced thrombocytopenia results from inhibition of thrombopoietin signaling in early megakaryopoiesis. |
| Volume: |
130 |
| Issue: |
9 |
| Pages: |
1132-1143 |
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•
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•
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| Publication |
| First Author: |
Kim J |
| Year: |
2016 |
| Journal: |
Nature |
| Title: |
XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer. |
| Volume: |
538 |
| Issue: |
7623 |
| Pages: |
114-117 |
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•
•
•
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| Publication |
| First Author: |
Sáinz-Jaspeado M |
| Year: |
2021 |
| Journal: |
Circulation |
| Title: |
Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium. |
| Volume: |
144 |
| Issue: |
20 |
| Pages: |
1629-1645 |
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•
•
•
|
| Publication |
| First Author: |
Kawai J |
| Year: |
2001 |
| Journal: |
Nature |
| Title: |
Functional annotation of a full-length mouse cDNA collection. |
| Volume: |
409 |
| Issue: |
6821 |
| Pages: |
685-90 |
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•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2000 |
| Journal: |
Genome Res |
| Title: |
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. |
| Volume: |
10 |
| Issue: |
10 |
| Pages: |
1617-30 |
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•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
1999 |
| Journal: |
Methods Enzymol |
| Title: |
High-efficiency full-length cDNA cloning. |
| Volume: |
303 |
|
| Pages: |
19-44 |
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•
•
•
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| Publication |
| First Author: |
Shibata K |
| Year: |
2000 |
| Journal: |
Genome Res |
| Title: |
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. |
| Volume: |
10 |
| Issue: |
11 |
| Pages: |
1757-71 |
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•
•
•
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| Publication |
| First Author: |
Katayama S |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
Antisense transcription in the mammalian transcriptome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1564-6 |
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•
•
•
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| Publication |
| First Author: |
Gerhard DS |
| Year: |
2004 |
| Journal: |
Genome Res |
| Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
| Volume: |
14 |
| Issue: |
10B |
| Pages: |
2121-7 |
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