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Search results 201 to 300 out of 426 for Zp3

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Type Details Score
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication  
First Author: Lou YH
Year: 1996
Journal: J Reprod Fertil Suppl
Title: Influence of autoimmune ovarian disease pathogenesis on ZP3 contraceptive vaccine design.
Volume: 50
Pages: 159-63
Publication
First Author: van Duin M
Year: 1993
Journal: Cytogenet Cell Genet
Title: The human gene for the zona pellucida glycoprotein ZP3 and a second polymorphic locus are located on chromosome 7.
Volume: 63
Issue: 2
Pages: 111-3
Transgene
Type: transgene
Organism: mouse, laboratory
Allele
Name: transgene insertion 1, Frank Grosveld
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: transgene insertion 82, Barbara B Knowles
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: transgene insertion 1, Gerald W Hart
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: transgene insertion 1, Eli Y Adashi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 2, Eli Y Adashi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: mutant strain, transgenic, coisogenic
Publication      
First Author: de Vries W
Year: 2011
Journal: Personal Communication
Title: Tg(Zp3-cre)82Knw inserted into Chromosome 2
Allele
Name: transgene insertion 1, Kathleen Molyneaux
Allele Type: Transgenic
Attribute String: Knockdown, Reporter
Allele
Name: transgene insertion ZP3, Jurrien Dean
Allele Type: Transgenic
Attribute String: Recombinase, Reporter
Publication
First Author: Shi S
Year: 2004
Journal: Mol Cell Biol
Title: Inactivation of the Mgat1 gene in oocytes impairs oogenesis, but embryos lacking complex and hybrid N-glycans develop and implant.
Volume: 24
Issue: 22
Pages: 9920-9
Strain
Attribute String: transgenic, mutant strain
Strain
Attribute String: mutant stock, transgenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Allele
Name: transgene insertion 76.12, Mouse Clinical Institute
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Genotype
Symbol: Tg(Zp3-siH1foo)1Eya/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Zp3-siH1foo)2Eya/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Figla-EGFP,-icre)ZP3Dean/?
Background: FVB/N-Tg(Figla-EGFP,-icre)ZP3Dean
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Williams SA
Year: 2007
Journal: J Cell Sci
Title: Fertilization in mouse does not require terminal galactose or N-acetylglucosamine on the zona pellucida glycans.
Volume: 120
Issue: Pt 8
Pages: 1341-9
Allele
Name: gastrulation brain homeobox 2; targeted mutation 1.1, Gail R Martin
Allele Type: Targeted
Attribute String: Null/knockout
Publication
First Author: Alfieri JA
Year: 2003
Journal: J Cell Sci
Title: Infertility in female mice with an oocyte-specific knockout of GPI-anchored proteins.
Volume: 116
Issue: Pt 11
Pages: 2149-55
Publication
First Author: Shafi R
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny.
Volume: 97
Issue: 11
Pages: 5735-9
Publication
First Author: Kaune H
Year: 2015
Journal: Theriogenology
Title: Oocyte-derived Smad4 is not required for development of the oocyte or the preimplantation embryo.
Volume: 83
Issue: 5
Pages: 897-903
Publication
First Author: Christensen AP
Year: 2015
Journal: Dev Biol
Title: Oocyte glycoproteins regulate the form and function of the follicle basal lamina and theca cells.
Volume: 401
Issue: 2
Pages: 287-98
Publication
First Author: Williams SA
Year: 2009
Journal: Reproduction
Title: Oocyte-specific deletion of complex and hybrid N-glycans leads to defects in preovulatory follicle and cumulus mass development.
Volume: 137
Issue: 2
Pages: 321-31
Strain
Attribute String: congenic, mutant strain, targeted mutation
Genotype
Symbol: Mgat1/Mgat1 Tg(Zp3-cre)1Gwh/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Piga/Piga Tg(Zp3-cre)1Gwh/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ogt/? Tg(Zp3-cre)1Gwh/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ogt/Ogt<+> Tg(Zp3-cre)1Gwh/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ogt/Ogt Tg(Zp3-cre)1Gwh/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Grasa P
Year: 2015
Journal: FASEB J
Title: Oocytes lacking O-glycans alter follicle development and increase fertility by increasing follicle FSH sensitivity, decreasing apoptosis, and modifying GDF9:BMP15 expression.
Volume: 29
Issue: 2
Pages: 525-39
Publication
First Author: Schmid RS
Year: 2008
Journal: Neuroreport
Title: A methyl-CpG-binding protein 2-enhanced green fluorescent protein reporter mouse model provides a new tool for studying the neuronal basis of Rett syndrome.
Volume: 19
Issue: 4
Pages: 393-8
Publication
First Author: Ploutarchou P
Year: 2015
Journal: Reproduction
Title: Molecular analysis of the cumulus matrix: insights from mice with O-glycan-deficient oocytes.
Volume: 149
Issue: 5
Pages: 533-43
Publication  
First Author: Sheikh S
Year: 2023
Journal: Front Cell Dev Biol
Title: Rescue of follicle development after oocyte-induced ovary dysfunction and infertility in a model of POI.
Volume: 11
Pages: 1202411
Allele
Name: transgene insertion 1, Jurrien Dean
Allele Type: Transgenic
Attribute String: Reporter
Genotype
Symbol: Mgat1/Mgat1 Tg(Zp3-cre)1Gwh/?
Background: involves: 129/Sv * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: C1galt1/C1galt1 Mgat1/Mgat1 Tg(Zp3-cre)1Gwh/?
Background: involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: C1galt1/C1galt1 Tg(Zp3-cre)1Gwh/?
Background: involves: 129S1/Sv * 129S1/SvImJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: C1galt1/C1galt1 Mgat1/Mgat1 Tg(Zp3-cre)1Gwh/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ror2/Ror2 Tg(Zp3-cre)82Knw/?
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 653  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 652  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 312  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 641  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 195  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 641  
Fragment?: false
Protein Domain
Type: Domain
Description: The zona pellucida (ZP) domain is a protein polymerisation module of ~260amino acid module, which is found at the C terminus of many secretedeukaryotic glycoproteins that play fundamental roles in development, hearing,immunity, and cancer [, , , ].Proteins containing a ZP domain include:Sperm receptor proteins ZP2 and ZP3. Along with protein ZP1, proteins ZP2and ZP3 are responsible for sperm-adhesion to the zona pellucida. ZP3 firstbinds to specific sperm proteins, thus mediating sperm contacts with theoocyte. ZP2 acts as a second sperm receptor reinforcing the interactions.ZP1 cross-links the polymers formed by ZP2 and ZP3.Zona pellucida sperm-binding protein B (ZP-B) (also known as ZP-X in rabbitand ZP-3 alpha in pig).Glycoprotein GP2, the major component of pancreatic secretory granulemembranes.TGF-beta receptor type III (also known as betaglycan). This protein is aproteoglycan that binds to TGF-beta and could be involved in capturing andretaining TGF-beta for presentation to the signalling receptors.Uromodulin (also known as Tamm-Horsfall urinary glycoprotein). The functionof this protein, which is the most abundant in human urine, is not yetclear.Chicken beta-tectorin, a major glycoprotein of avian tectorial membrane.Most ZP domain proteins are synthesized as precursors with carboxy-terminaltransmembrane domains or glycosyl phosphatidylinositol (GPI) anchors [].The ZP domain contains eight strictly conserved cysteines, which formdisulphide bridges. The disulphide bonds within the ZP domains are divided intotwo groups, suggesting that the ZP domain consists of two subdomains. Inaddition to the conserved cysteines, only a few aromatic or hydrophobic aminoacids are absolutely invariant, probably as a result of structural rather thanfunctional constraints [, , ].
Publication
First Author: Ohtsubo K
Year: 2005
Journal: Cell
Title: Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin secretion in suppressing diabetes.
Volume: 123
Issue: 7
Pages: 1307-21
Strain
Attribute String: congenic, mutant strain, targeted mutation
Publication
First Author: Wassarman KM
Year: 1997
Journal: Development
Title: Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function.
Volume: 124
Issue: 15
Pages: 2923-34
Publication
First Author: Li JY
Year: 2005
Journal: Development
Title: New regulatory interactions and cellular responses in the isthmic organizer region revealed by altering Gbx2 expression.
Volume: 132
Issue: 8
Pages: 1971-81
Publication
First Author: Lin Z
Year: 2005
Journal: Development
Title: Gbx2 is required for the morphogenesis of the mouse inner ear: a downstream candidate of hindbrain signaling.
Volume: 132
Issue: 10
Pages: 2309-18
Publication
First Author: Millet S
Year: 1999
Journal: Nature
Title: A role for Gbx2 in repression of Otx2 and positioning the mid/hindbrain organizer.
Volume: 401
Issue: 6749
Pages: 161-4
Publication
First Author: Carapuço M
Year: 2005
Journal: Genes Dev
Title: Hox genes specify vertebral types in the presomitic mesoderm.
Volume: 19
Issue: 18
Pages: 2116-21
Publication
First Author: Miyashita-Lin EM
Year: 1999
Journal: Science
Title: Early neocortical regionalization in the absence of thalamic innervation.
Volume: 285
Issue: 5429
Pages: 906-9
Publication
First Author: He ZY
Year: 2003
Journal: Dev Biol
Title: None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm-egg binding and fusion.
Volume: 254
Issue: 2
Pages: 226-37
Publication  
First Author: Barraud-Lange V
Year: 2020
Journal: Int J Mol Sci
Title: Partial Sperm beta1 Integrin Subunit Deletion Proves its Involvement in Mouse Gamete Adhesion/Fusion.
Volume: 21
Issue: 22
Publication
First Author: Williams SA
Year: 2011
Journal: Endocrinology
Title: Premature ovarian failure in mice with oocytes lacking core 1-derived O-glycans and complex N-glycans.
Volume: 152
Issue: 3
Pages: 1057-66
Publication
First Author: Grasa P
Year: 2012
Journal: Reproduction
Title: Embryos generated from oocytes lacking complex N- and O-glycans have compromised development and implantation.
Volume: 144
Issue: 4
Pages: 455-65
Publication
First Author: Grasa P
Year: 2016
Journal: Reproduction
Title: Dysregulation of follicle development in a mouse model of premature ovarian insufficiency.
Volume: 152
Issue: 5
Pages: 591-601
Publication
First Author: Stahl M
Year: 2006
Journal: Cancer Res
Title: Notch1-induced transformation of RKE-1 cells requires up-regulation of cyclin D1.
Volume: 66
Issue: 15
Pages: 7562-70
Publication
First Author: Pandolfi EC
Year: 2018
Journal: Mol Neurobiol
Title: Haploinsufficiency of SIX3 Abolishes Male Reproductive Behavior Through Disrupted Olfactory Development, and Impairs Female Fertility Through Disrupted GnRH Neuron Migration.
Volume: 55
Issue: 11
Pages: 8709-8727
Allele
Name: transgene insertion 7812, Jurrien Dean
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication      
First Author: Kihara M
Year: 2005
Journal: MGI Direct Data Submission
Title: Oocytes from H1foo knockout mice develop normally
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Strain
Attribute String: mutant strain, transgenic
Strain
Attribute String: mutant strain, transgenic, coisogenic
Publication
First Author: Chen Z
Year: 2015
Journal: J Biol Chem
Title: Rictor/mTORC2 pathway in oocytes regulates folliculogenesis, and its inactivation causes premature ovarian failure.
Volume: 290
Issue: 10
Pages: 6387-96
Publication    
First Author: Farzi A
Year: 2018
Journal: Elife
Title: Arcuate nucleus and lateral hypothalamic CART neurons in the mouse brain exert opposing effects on energy expenditure.
Volume: 7
Genotype
Symbol: Gbx2/Gbx2
Background: B6.129-Gbx2
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gbx2/Gbx2
Background: either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J) or (involves: 129S1/Sv * 129X1/SvJ * FVB/N)
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gbx2/Gbx2
Background: involves: 129S1/Sv * 129X1/SvJ * Swiss Webster
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gbx2/Gbx2
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * SJL
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Gbx2/Gbx2
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Gbx2/Gbx2
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gbx2/Gbx2
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 531  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 413  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 534  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 297  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 534  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 679  
Fragment?: false
Publication
First Author: Cocchia M
Year: 2000
Journal: Genomics
Title: PLAC1, an Xq26 gene with placenta-specific expression.
Volume: 68
Issue: 3
Pages: 305-12
Publication  
First Author: Tokuhiro K
Year: 2015
Journal: Sci Rep
Title: Calreticulin is required for development of the cumulus oocyte complex and female fertility.
Volume: 5
Pages: 14254
Publication
First Author: Bruch J
Year: 1996
Journal: Cytogenet Cell Genet
Title: Mapping of type I loci from human chromosome 7 reveals segments of conserved synteny on pig chromosomes 3, 9, and 18.
Volume: 73
Issue: 3
Pages: 164-7
Publication
First Author: Garza KM
Year: 1997
Journal: Immunity
Title: Neonatal injection of an ovarian peptide induces autoimmune ovarian disease in female mice: requirement of endogenous neonatal ovaries.
Volume: 6
Issue: 1
Pages: 89-96