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Search results 2001 to 2100 out of 4306 for C3

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Type Details Score
Publication
22322303 | J:181999
First Author: Sun WY
Year: 2012
Journal: Am J Pathol
Title: Rapid histamine-induced neutrophil recruitment is sphingosine kinase-1 dependent.
Volume: 180
Issue: 4
Pages: 1740-50
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Strain
MGI:5708837 | B6;D-Tg(tetO-lacZ,-GFP/Gria2)1Rsp/Kctt
Attribute String: mutant stock, transgenic
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Strain
MGI:5708844 | B6;D-Tg(tetO-lacZ,-GFP/Gria2)6Rsp/Kcct
Attribute String: mutant stock, transgenic
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Strain
MGI:5824742 | B6.Cg-Tg(PMP22)C3Fbas
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:7610527 | B6.Cg-Tg(PMP22)C3Fbas/2J
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:5817411 | B6.Cg-Tg(PMP22)C3Fbas/J
Attribute String: congenic, mutant strain, transgenic
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Genotype
Genotype
Symbol: Prlr/Prlr Tg(C3-1-TAg)cJeg/?
Background: involves: 129P2/OlaHsd * 129S2/SvPas * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+>
Background: involves: 129S4/SvJae
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(PMP22)C3Fbas/?
Background: B6.Cg-Tg(PMP22)C3Fbas
Zygosity: ot
Has Mutant Allele: true
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Publication
12356749 | -
First Author: Matias PM
Year: 2002
Journal: J Biol Chem
Title: Sulfate respiration in Desulfovibrio vulgaris Hildenborough. Structure of the 16-heme cytochrome c HmcA AT 2.5-A resolution and a view of its role in transmembrane electron transfer.
Volume: 277
Issue: 49
Pages: 47907-16
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Publication
12467575 | -
First Author: Czjzek M
Year: 2002
Journal: Structure
Title: The crystal structure of the hexadeca-heme cytochrome Hmc and a structural model of its complex with cytochrome c(3).
Volume: 10
Issue: 12
Pages: 1677-86
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Publication
11041344 | -
First Author: Dolla A
Year: 2000
Journal: Arch Microbiol
Title: Deletion of the hmc operon of Desulfovibrio vulgaris subsp. vulgaris Hildenborough hampers hydrogen metabolism and low-redox-potential niche establishment.
Volume: 174
Issue: 3
Pages: 143-51
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Publication
10606770 | -
First Author: Aubert C
Year: 2000
Journal: Biochim Biophys Acta
Title: A sequential electron transfer from hydrogenases to cytochromes in sulfate-reducing bacteria.
Volume: 1476
Issue: 1
Pages: 85-92
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Protein Domain
IPR002322 | Cyt_c_III
Type: Family
Description: Cytochromes c (cytC) can be defined as electron-transfer proteins having one or several haem c groups, bound to the protein by one or, more generally, two thioether bonds involving sulphydryl groups of cysteine residues. The fifth haem iron ligand is always provided by a histidine residue. CytC possess a wide range of properties and function in a large number of different redox processes []. Ambler []recognised four classes of cytC.Class III comprises the low redox potential multiple haem cytochromes: cyt C7 (trihaem), C3 (tetrahaem),and high-molecular-weight cytC, HMC (hexadecahaem), with only 30-40 residues per haem group. The haem c groups, all bis-histidinyl coordinated,are structurally and functionally nonequivalent and present different redoxpotentials in the range 0 to -400 mV []. The 3D structures of a number of cyt C3 proteins have been determined. The proteinsconsist of 4-5 α-helices and 2 β-strands wrapped around a compactcore of four non-parallel haems, which present a relatively high degree of exposure to the solvent. The overall protein architecture, haem plane orientations and iron-iron distances are highly conserved [].
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Protein Domain
IPR011346 | Cyt_cc3
Type: Family
Description: Cytochromes c (cytC) can be defined as electron-transfer proteins having one or several haem c groups, bound to the protein by one or, more generally, two thioether bonds involving sulphydryl groups of cysteine residues. The fifth haem iron ligand is always provided by a histidine residue. CytC possess a wide range of properties and function in a large number of different redox processes.This family, found in sulphate-reducers, represents a cytochrome containing sixteen haem groups which forms part of a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyse reduction of sulphates []. HmcA () from Desulfovibrio vulgaris strain Hildenborough is composed of three distinct regions; an N-terminal three-haem domain homologous to cytochrome c7, a four-haem cyctochrome c3-like domain, and a C-terminal nine-haem cytochrome Hcc-like domain [, ]. This last domain is composed of two cytochrome c3-like domains with an isolated haem group inserted between them. HcmA interacts specifically with cytochrome c3 [], where the last haem group of HcmA and haem four of cytochrome c3 interact to provide the likely site of electron transfer between molecules [].
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Protein Domain
IPR020942 | Cyt_c_III_dom
Type: Domain
Description: Cytochromes c (cytC) can be defined as electron-transfer proteins having one or several haem c groups, bound to the protein by one or, more generally, two thioether bonds involving sulphydryl groups of cysteine residues. The fifth haem iron ligand is always provided by a histidine residue. CytC possess a wide range of properties and function in a large number of different redox processes [].Ambler []recognised four classes of cytC.Class III comprises the low redox potential multiple haem cytochromes: C3 (tetrahaem),and high-molecular-weight cytC, HMC (hexadecahaem), with only 30-40 residues per haem group. The haem c groups, all bis-histidinyl coordinated,are structurally andfunctionally nonequivalent and present different redoxpotentials in the range 0 to -400 mV []. The 3D structures of a number of cyt C3 proteins have been determined. The proteinsconsist of 4-5 α-helices and 2 β-strands wrapped around a compactcore of four non-parallel haems, which present a relatively high degree of exposure to the solvent. The overall protein architecture, haem plane orientations and iron-iron distances are highly conserved [].
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HT Experiment
GSE30 | Multiplex three dimensional brain gene expression mapping in a mouse model of Parkinson's disease
 
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: GEO
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Publication
8604219 | J:31869
First Author: Minta JO
Year: 1996
Journal: Mol Immunol
Title: cDNA cloning, sequencing and chromosomal assignment of the gene for mouse complement factor I (C3b/C4b inactivator): identification of a species specific divergent segment in factor I.
Volume: 33
Issue: 1
Pages: 101-12
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Publication
12213736 | J:78874
First Author: Miwa T
Year: 2002
Journal: Am J Pathol
Title: Deletion of decay-accelerating factor (CD55) exacerbates autoimmune disease development in MRL/lpr mice.
Volume: 161
Issue: 3
Pages: 1077-86
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Publication
11907125 | J:75572
First Author: Bao L
Year: 2002
Journal: J Immunol
Title: Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr mice.
Volume: 168
Issue: 7
Pages: 3601-7
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Publication
20941861 | J:165497
First Author: Kimura Y
Year: 2010
Journal: J Clin Invest
Title: Genetic and therapeutic targeting of properdin in mice prevents complement-mediated tissue injury.
Volume: 120
Issue: 10
Pages: 3545-54
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Publication
19036700 | J:145551
First Author: Kinderlerer AR
Year: 2009
Journal: Blood
Title: Heme oxygenase-1 expression enhances vascular endothelial resistance to complement-mediated injury through induction of decay-accelerating factor: a role for increased bilirubin and ferritin.
Volume: 113
Issue: 7
Pages: 1598-607
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Publication
17947652 | J:153009
First Author: Lalli PN
Year: 2007
Journal: J Immunol
Title: Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production.
Volume: 179
Issue: 9
Pages: 5793-802
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Publication
14764738 | J:88060
First Author: Lin F
Year: 2004
Journal: J Immunol
Title: Respective roles of decay-accelerating factor and CD59 in circumventing glomerular injury in acute nephrotoxic serum nephritis.
Volume: 172
Issue: 4
Pages: 2636-42
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Publication
9892684 | J:52968
First Author: Sun X
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Role of decay-accelerating factor in regulating complement activation on the erythrocyte surface as revealed by gene targeting.
Volume: 96
Issue: 2
Pages: 628-33
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Strain
MGI:5425110 | C57BL/6JArc
Attribute String: inbred strain
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Publication
28739878 | J:251071
First Author: Banda NK
Year: 2017
Journal: J Immunol
Title: Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein-Associated Serine Protease 2.
Volume: 199
Issue: 5
Pages: 1835-1845
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Publication
9275178 | J:42822
First Author: Nakagawa T
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.
Volume: 94
Issue: 18
Pages: 9654-9
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Publication
24378336 | J:206879
First Author: Huang T
Year: 2014
Journal: Dev Biol
Title: BDNF and NT4 play interchangeable roles in gustatory development.
Volume: 386
Issue: 2
Pages: 308-20
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Publication
21536733 | J:171415
First Author: Castro DS
Year: 2011
Journal: Genes Dev
Title: A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets.
Volume: 25
Issue: 9
Pages: 930-45
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Publication
1610875 | -
First Author: Gietl C
Year: 1992
Journal: Biochim Biophys Acta
Title: Malate dehydrogenase isoenzymes: cellular locations and role in the flow of metabolites between the cytoplasm and cell organelles.
Volume: 1100
Issue: 3
Pages: 217-34
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Publication
17222594 | -
First Author: Ruzicka FJ
Year: 2007
Journal: Biochim Biophys Acta
Title: Glutamate 2,3-aminomutase: a new member of the radical SAM superfamily of enzymes.
Volume: 1774
Issue: 2
Pages: 286-96
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Publication
18536718 | -
First Author: Fredslund F
Year: 2008
Journal: Nat Immunol
Title: Structure of and influence of a tick complement inhibitor on human complement component 5.
Volume: 9
Issue: 7
Pages: 753-60
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Publication
8182049 | -
First Author: DeMartino JA
Year: 1994
Journal: J Biol Chem
Title: The amino terminus of the human C5a receptor is required for high affinity C5a binding and for receptor activation by C5a but not C5a analogs.
Volume: 269
Issue: 20
Pages: 14446-50
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Protein Domain
IPR001252 | Malate_DH_AS
Type: Active_site
Description: Malate dehydrogenase () (MDH) []catalyzes the interconversionof malate to oxaloacetate utilizing the NAD/NADH cofactor system. The enzymeparticipates in the citric acid cycle and exists in allaerobics organisms.While prokaryotic organisms contains a single form of MDH, in eukaryotic cellsthere are two isozymes: one which is located in the mitochondrial matrix andthe other in the cytoplasm. Fungi and plants also harbor a glyoxysomal formwhich functions in the glyoxylate pathway. In plants chloroplast there is anadditional NADP-dependent form of MDH () which is essential forboth the universal C3 photosynthesis (Calvin) cycle and the more specialisedC4 cycle.The pattern for this enzyme includestwo residues involved in the catalytic mechanism []: an aspartic acid whichis involved in a proton relay mechanism, and an arginine which binds thesubstrate.
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Protein Domain
IPR037562 | Complement_C5
Type: Family
Description: This entry represents complement factor 5 (C5; MEROPS identifier I39.952). C5 is a component of the lytic complex consisting of factors C5-C9 which attacks bacterial cell membranes. C5 is synthesized as a precursor and is activated by a C5 convertase. The anaphylatoxin C5a is released and is a mediator of local inflammation. C5a is also a chemokine, directing polymorphonuclear leukocytes to the site of infammation. C5a binds to the receptor C5AR1, which results in intracellular calcium release, smooth muscle contraction, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes []. The tertiary structure of C5 has been solved and the fold is similar to that of complement C3 and the peptidase inhibitor alpha2-macroglobulin [].
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Protein Domain
IPR000199 | Peptidase_C3A/C3B_picornavir
Type: Domain
Description: Viruses in the order Picornavirales infect different vertebrate, invertebrate, and plant hosts and are responsible for a variety of human, animal, and plant diseases. These viruses have a single-stranded, positive sense RNA genome that generally translates a large precursor polyprotein which is proteolytically cleaved after translation to generate mature functional viral proteins. This process is usually mediated by (more than one) proteases, and a 3C (for the family Picornaviridae) or 3C-like (3CL) protease (for other families) plays a central role in the cleavage of the viral precursor polyprotein. In addition to this key role, 3C/3C-like protease is able to cleave a number of host proteins to remodel the cellular environment for virus reproduction [, , , , , ]. The Picornavirales 3C/3C-like protease domain forms the MEROPS peptidase family C3 (picornain family) of clan PA.The 3C/3CL protease domain adopts a chymotrypsin-like fold with a cysteine nucleophile in place of a commonly found serine which suggests that the cysteine and serine perform an analogous catalytic function. The catalytic triad is made of a histidine, an aspartate/glutamate and the conserved cysteine in this sequential order. The 3C/3CL protease domain folds into two antiparallel beta barrels that are linked by a loop with a short α-helix in its middle, and flanked by two other α-helices at the N- and C-terminal. The two barrels are topologically equivalent and are formed by six antiparallel beta strands with the first four organised into a Greek key motif. The active-site residues are located in the cleft between the two barrels with the nucleophilic Cys from the C-terminal barrel and the general acid base His-Glu/Asp from the N-terminal barrel [, , ].This entry includes cysteine peptidases that belong to MEROPS peptidase family C3 (picornain, clan PA(C)), subfamilies C3A and C3B.
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Publication
20502675 | J:160677
First Author: Yang J
Year: 2010
Journal: PLoS Genet
Title: Ablation of whirlin long isoform disrupts the USH2 protein complex and causes vision and hearing loss.
Volume: 6
Issue: 5
Pages: e1000955
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Publication
39178128 | J:355223
 
First Author: Cassinotti LR
Year: 2024
Journal: JCI Insight
Title: Hidden hearing loss in a Charcot-Marie-Tooth type 1A mouse model.
Volume: 9
Issue: 19
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Publication
16862169 | J:117839
First Author: Oakes SR
Year: 2007
Journal: Oncogene
Title: Loss of mammary epithelial prolactin receptor delays tumor formation by reducing cell proliferation in low-grade preinvasive lesions.
Volume: 26
Issue: 4
Pages: 543-53
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Publication
27799486 | J:292972
First Author: Bajwa A
Year: 2017
Journal: J Am Soc Nephrol
Title: Sphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-γ.
Volume: 28
Issue: 4
Pages: 1145-1161
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Publication
18424450 | J:137634
First Author: Wu YP
Year: 2008
Journal: Hum Mol Genet
Title: Sphingosine kinase 1/S1P receptor signaling axis controls glial proliferation in mice with Sandhoff disease.
Volume: 17
Issue: 15
Pages: 2257-64
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Publication
16141391 | J:104208
First Author: Wang Z
Year: 2005
Journal: Endocrinology
Title: Disruption of growth hormone signaling retards early stages of prostate carcinogenesis in the C3(1)/T antigen mouse.
Volume: 146
Issue: 12
Pages: 5188-96
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Publication
16916863 | J:116587
First Author: Zhang X
Year: 2007
Journal: Carcinogenesis
Title: Inhibition of estrogen-independent mammary carcinogenesis by disruption of growth hormone signaling.
Volume: 28
Issue: 1
Pages: 143-50
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Publication
34043703 | J:306421
First Author: Velazquez FN
Year: 2021
Journal: PLoS One
Title: Loss of sphingosine kinase 1 increases lung metastases in the MMTV-PyMT mouse model of breast cancer.
Volume: 16
Issue: 5
Pages: e0252311
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Publication
28581527 | J:248160
First Author: Song W
Year: 2017
Journal: Oncogene
Title: Targeting EphA2 impairs cell cycle progression and growth of basal-like/triple-negative breast cancers.
Volume: 36
Issue: 40
Pages: 5620-5630
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Publication
25895971 | J:229776
First Author: Farnoud AM
Year: 2015
Journal: Infect Immun
Title: The Granuloma Response Controlling Cryptococcosis in Mice Depends on the Sphingosine Kinase 1-Sphingosine 1-Phosphate Pathway.
Volume: 83
Issue: 7
Pages: 2705-13
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Publication
22747486 | J:191026
First Author: Kharel Y
Year: 2012
Journal: Biochem J
Title: Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate.
Volume: 447
Issue: 1
Pages: 149-57
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Publication
20644167 | J:162620
First Author: Baker DA
Year: 2010
Journal: J Immunol
Title: Genetic sphingosine kinase 1 deficiency significantly decreases synovial inflammation and joint erosions in murine TNF-alpha-induced arthritis.
Volume: 185
Issue: 4
Pages: 2570-9
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Publication
36361636 | J:331578
 
First Author: Thuy AV
Year: 2022
Journal: Int J Mol Sci
Title: The Impact of Sphingosine Kinases on Inflammation-Induced Cytokine Release and Vascular Endothelial Barrier Integrity.
Volume: 23
Issue: 21
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Publication
30997640 | J:279809
First Author: Wilkerson JL
Year: 2019
Journal: Mol Neurobiol
Title: Sphingosine Kinase-1 Is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina.
Volume: 56
Issue: 10
Pages: 7188-7207
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Publication
22668972 | J:202209
First Author: Yang J
Year: 2012
Journal: Circulation
Title: Proximal cerebral arteries develop myogenic responsiveness in heart failure via tumor necrosis factor-α-dependent activation of sphingosine-1-phosphate signaling.
Volume: 126
Issue: 2
Pages: 196-206
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Publication
28082452 | J:259018
First Author: Meissner A
Year: 2017
Journal: Cardiovasc Res
Title: Sphingosine-1-phosphate signalling-a key player in the pathogenesis of Angiotensin II-induced hypertension.
Volume: 113
Issue: 2
Pages: 123-133
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Publication
25505239 | J:217879
First Author: Mizugishi K
Year: 2015
Journal: J Biol Chem
Title: Sphingolipid pathway regulates innate immune responses at the fetomaternal interface during pregnancy.
Volume: 290
Issue: 4
Pages: 2053-68
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Publication
23933064 | J:200913
First Author: Harijith A
Year: 2013
Journal: Am J Pathol
Title: Sphingosine kinase 1 deficiency confers protection against hyperoxia-induced bronchopulmonary dysplasia in a murine model: role of S1P signaling and Nox proteins.
Volume: 183
Issue: 4
Pages: 1169-82
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Publication
26283908 | J:290048
 
First Author: Canlas J
Year: 2015
Journal: Front Mol Neurosci
Title: Sphingosine kinase 2-deficiency mediated changes in spinal pain processing.
Volume: 8
Pages: 29
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Publication
22759398 | J:188547
First Author: Park SW
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: A1 adenosine receptor allosteric enhancer PD-81723 protects against renal ischemia-reperfusion injury.
Volume: 303
Issue: 5
Pages: F721-32
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Publication
21849969 | J:194715
First Author: Park SW
Year: 2011
Journal: Kidney Int
Title: Sphingosine kinase 1 protects against renal ischemia-reperfusion injury in mice by sphingosine-1-phosphate1 receptor activation.
Volume: 80
Issue: 12
Pages: 1315-27
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Publication
22095950 | J:315823
First Author: Park SW
Year: 2012
Journal: J Am Soc Nephrol
Title: Inhibition of sphingosine 1-phosphate receptor 2 protects against renal ischemia-reperfusion injury.
Volume: 23
Issue: 2
Pages: 266-80
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Publication
25180446 | J:267940
First Author: Chen J
Year: 2014
Journal: Am J Respir Crit Care Med
Title: The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension.
Volume: 190
Issue: 9
Pages: 1032-43
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Publication
20194596 | J:159182
First Author: McQuiston T
Year: 2010
Journal: Infect Immun
Title: Role of host sphingosine kinase 1 in the lung response against Cryptococcosis.
Volume: 78
Issue: 5
Pages: 2342-52
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Publication
23359503 | J:193463
First Author: Dillahunt SE
Year: 2013
Journal: J Immunol
Title: Usage of sphingosine kinase isoforms in mast cells is species and/or cell type determined.
Volume: 190
Issue: 5
Pages: 2058-67
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Publication
17885683 | J:127536
First Author: Mizugishi K
Year: 2007
Journal: J Clin Invest
Title: Maternal disturbance in activated sphingolipid metabolism causes pregnancy loss in mice.
Volume: 117
Issue: 10
Pages: 2993-3006
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Publication
18824518 | J:146029
First Author: Kawamori T
Year: 2009
Journal: FASEB J
Title: Role for sphingosine kinase 1 in colon carcinogenesis.
Volume: 23
Issue: 2
Pages: 405-14
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Publication
22859402 | J:188619
First Author: Lee HT
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Interleukin-11 protects against renal ischemia and reperfusion injury.
Volume: 303
Issue: 8
Pages: F1216-24
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Publication
30251698 | J:270611
First Author: Zhu X
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Sphingosine kinase 2 cooperating with Fyn promotes kidney fibroblast activation and fibrosis via STAT3 and AKT.
Volume: 1864
Issue: 11
Pages: 3824-3836
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Publication
23315259 | J:197758
First Author: Huang LS
Year: 2013
Journal: FASEB J
Title: Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis.
Volume: 27
Issue: 4
Pages: 1749-60
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Publication
28842426 | J:256409
First Author: Mizugishi K
Year: 2017
Journal: FASEB J
Title: Neutrophil extracellular traps are critical for pregnancy loss in sphingosine kinase-deficient mice on 129Sv/C57BL/6 background.
Volume: 31
Issue: 12
Pages: 5577-5591
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Publication
20671234 | J:178205
First Author: Hoefer J
Year: 2010
Journal: Circ Res
Title: Sphingosine-1-phosphate-dependent activation of p38 MAPK maintains elevated peripheral resistance in heart failure through increased myogenic vasoconstriction.
Volume: 107
Issue: 7
Pages: 923-33
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Strain
MGI:6144864 | B6.Cg-Tg(CAG-EGFP)50Osb/OsbRbrc
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:3760431 | B6;C3-Tg(CAG-EGFP)50Osb/OsbRbrc
Attribute String: mutant stock, transgenic
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Publication
2551778 | J:126028
First Author: Miyazaki J
Year: 1989
Journal: Gene
Title: Expression vector system based on the chicken beta-actin promoter directs efficient production of interleukin-5.
Volume: 79
Issue: 2
Pages: 269-77
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Genotype
Genotype
Symbol: Sphk1/Sphk1 Sphk2/Sphk2
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: C3/C3 Tg(Ins2-TFRC/OVA)296Wehi/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tcra/Tcra Tg(Mx1-cre)1Cgn/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: C3/C3 Del(2Cd59b-Cd59a)1Jha/Del(2Cd59b-Cd59a)1Jha
Background: involves: 129/Sv * 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-EGFP)50Osb/?
Background: involves: C3H/HeSlc * C57BL/6Slc
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tcra/Tcra Tg(Mx1-cre)1Cgn/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Publication
22792067 | J:195379
First Author: Ali YM
Year: 2012
Journal: PLoS Pathog
Title: The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection.
Volume: 8
Issue: 7
Pages: e1002793
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Publication
- | J:179727
 
First Author: Evans EP
Year: 1988
Journal: Mouse News Lett
Title: A splotch locus deletion visible by Giemsa banding
Volume: 81
Pages: 66
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Publication
- | J:44551
   
First Author: Morgante E
Year: 1997
Journal: Recent Adv Microscopy Cells Tissues Organs
Title: Compartmentalization of the third component of complement (C3) in 3LL murine carcinoma cells, studied by immunogold labeling.
Pages: 135-139
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Protein Coding Gene
MGI:105937 | Cfi
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0025628 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0027875 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0027833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0027798 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0027846 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027575 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_105937 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028290 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027032 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027551 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027692 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027659 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0027801 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027690 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028347 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026756 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027111 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027077 | -
Type: protein_coding_gene
Organism: Mus pahari
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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