| Type |
Details |
Score |
| Allele |
| Name: |
CDC42 effector protein 3; gene trap IST14332G8, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 2; gene trap IST14334H12, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 1; gene trap IST14362B4, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 3; gene trap IST14365C3, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 5; gene trap IST14343B8, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 1; gene trap IST14348F4, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 1; gene trap IST14451C7, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 3; gene trap IST14487E7, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 2; gene trap IST14430E5, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 1; gene trap IST14561E11, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 3; gene trap IST14530G7, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 2; gene trap IST14521H12, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 1; gene trap IST14559E12, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 3; gene trap IST14611A11, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 2; gene trap IST14641D5, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 5; gene trap IST14642F8, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 1; gene trap IST14685E6, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 4; gene trap IST14753C8, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 3; gene trap IST14834G6, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 3; gene trap IST14782D6, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 5; gene trap IST14821F11, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 1; gene trap IST14902C5, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 1; gene trap IST14854B8, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 2; gene trap IST14987H7, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 3; gene trap IST14968B3, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 3; gene trap IST14995B4, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 5; gene trap IST14950A4, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 2; gene trap IST14978C10, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 3; gene trap IST14959B7, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 3; gene trap IST15024A5, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 1; gene trap IST15035A4, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 3; gene trap IST15049A7, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 2; gene trap IST15052H10, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 4; gene trap IST15010G11, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 2; gene trap IST15082A11, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 2; gene trap IST15022H9, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 binding protein kinase beta; targeted mutation 1a, Wellcome Trust Sanger Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 4; targeted mutation 1a, Wellcome Trust Sanger Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 small effector 2; targeted mutation 1a, Wellcome Trust Sanger Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, targeted mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 effector protein 3; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 binding protein kinase gamma; endonuclease-mediated mutation 1, Baylor College of Medicine |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Allele |
| Name: |
CDC42 guanine nucleotide exchange factor 9; endonuclease-mediated mutation 1, Cyagen Biosciences |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cdc42ep1/Cdc42ep1 |
| Background: |
B6.Cg-Cdc42ep1 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cdc42ep4/Cdc42ep4 |
| Background: |
involves: C57BL/6 * C57BL/6N |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cdc42bpb/Cdc42bpb |
| Background: |
C57BL/6NJ-Cdc42bpb/J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Krause-Gruszczynska M |
| Year: |
2011 |
| Journal: |
Cell Commun Signal |
| Title: |
The signaling pathway of Campylobacter jejuni-induced Cdc42 activation: Role of fibronectin, integrin beta1, tyrosine kinases and guanine exchange factor Vav2. |
| Volume: |
9 |
|
| Pages: |
32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rudolph MG |
| Year: |
1998 |
| Journal: |
J Biol Chem |
| Title: |
The Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formation. |
| Volume: |
273 |
| Issue: |
29 |
| Pages: |
18067-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
de Groot C |
| Year: |
2017 |
| Journal: |
PLoS Genet |
| Title: |
RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of α2 GABAA receptors. |
| Volume: |
13 |
| Issue: |
10 |
| Pages: |
e1007073 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kalantry S |
| Year: |
2001 |
| Journal: |
Nat Genet |
| Title: |
The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain. |
| Volume: |
27 |
| Issue: |
4 |
| Pages: |
412-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Selimi F |
| Year: |
2009 |
| Journal: |
PLoS Biol |
| Title: |
Proteomic studies of a single CNS synapse type: the parallel fiber/purkinje cell synapse. |
| Volume: |
7 |
| Issue: |
4 |
| Pages: |
e83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Soykan T |
| Year: |
2014 |
| Journal: |
EMBO J |
| Title: |
A conformational switch in collybistin determines the differentiation of inhibitory postsynapses. |
| Volume: |
33 |
| Issue: |
18 |
| Pages: |
2113-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang XX |
| Year: |
2021 |
| Journal: |
J Biol Chem |
| Title: |
MRCKβ links Dasm1 to actin rearrangements to promote dendrite development. |
|
|
| Pages: |
100730 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1580
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ono Y |
| Year: |
2000 |
| Journal: |
Oncogene |
| Title: |
Two actions of frabin: direct activation of Cdc42 and indirect activation of Rac. |
| Volume: |
19 |
| Issue: |
27 |
| Pages: |
3050-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fu Y |
| Year: |
1999 |
| Journal: |
Nature |
| Title: |
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion. |
| Volume: |
401 |
| Issue: |
6750 |
| Pages: |
293-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Larocca MC |
| Year: |
2004 |
| Journal: |
Mol Biol Cell |
| Title: |
AKAP350 interaction with cdc42 interacting protein 4 at the Golgi apparatus. |
| Volume: |
15 |
| Issue: |
6 |
| Pages: |
2771-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Humphries AC |
| Year: |
2014 |
| Journal: |
J Cell Sci |
| Title: |
Cdc42 and the Rho GEF intersectin-1 collaborate with Nck to promote N-WASP-dependent actin polymerisation. |
| Volume: |
127 |
| Issue: |
Pt 3 |
| Pages: |
673-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Leung T |
| Year: |
1998 |
| Journal: |
Mol Cell Biol |
| Title: |
Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization. |
| Volume: |
18 |
| Issue: |
1 |
| Pages: |
130-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Morreale A |
| Year: |
2000 |
| Journal: |
Nat Struct Biol |
| Title: |
Structure of Cdc42 bound to the GTPase binding domain of PAK. |
| Volume: |
7 |
| Issue: |
5 |
| Pages: |
384-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rodal AA |
| Year: |
2008 |
| Journal: |
J Neurosci |
| Title: |
Nervous wreck and Cdc42 cooperate to regulate endocytic actin assembly during synaptic growth. |
| Volume: |
28 |
| Issue: |
33 |
| Pages: |
8316-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Steenblock C |
| Year: |
2014 |
| Journal: |
J Biol Chem |
| Title: |
The Cdc42 guanine nucleotide exchange factor FGD6 coordinates cell polarity and endosomal membrane recycling in osteoclasts. |
| Volume: |
289 |
| Issue: |
26 |
| Pages: |
18347-59 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schwamborn JC |
| Year: |
2004 |
| Journal: |
Nat Neurosci |
| Title: |
The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity. |
| Volume: |
7 |
| Issue: |
9 |
| Pages: |
923-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang B |
| Year: |
1998 |
| Journal: |
J Biol Chem |
| Title: |
Negative regulation of Rho family GTPases Cdc42 and Rac2 by homodimer formation. |
| Volume: |
273 |
| Issue: |
40 |
| Pages: |
25728-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kulkarni K |
| Year: |
2011 |
| Journal: |
J Biol Chem |
| Title: |
Multiple factors confer specific Cdc42 and Rac protein activation by dedicator of cytokinesis (DOCK) nucleotide exchange factors. |
| Volume: |
286 |
| Issue: |
28 |
| Pages: |
25341-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dubois T |
| Year: |
2005 |
| Journal: |
Med Sci (Paris) |
| Title: |
[ARHGAP10, a novel RhoGAP at the cross-road between ARF1 and Cdc42 pathways, regulates Arp2/3 complex and actin dynamics on Golgi membranes]. |
| Volume: |
21 |
| Issue: |
8-9 |
| Pages: |
692-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Oshima T |
| Year: |
2011 |
| Journal: |
Biol Pharm Bull |
| Title: |
Role of FGD1, a Cdc42 guanine nucleotide exchange factor, in epidermal growth factor-stimulated c-Jun NH2-terminal kinase activation and cell migration. |
| Volume: |
34 |
| Issue: |
1 |
| Pages: |
54-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aspenström P |
| Year: |
1997 |
| Journal: |
Curr Biol |
| Title: |
A Cdc42 target protein with homology to the non-kinase domain of FER has a potential role in regulating the actin cytoskeleton. |
| Volume: |
7 |
| Issue: |
7 |
| Pages: |
479-87 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Arhgef9/? |
| Background: |
B6.129P2-Arhgef9 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Arhgef9/? Tg(Camk2a-cre)2834Lusc/? |
| Background: |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cdc42bpb/Cdc42bpb<+> |
| Background: |
C57BL/6NJ-Cdc42bpb/J |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cdc42ep3/Cdc42ep3 |
| Background: |
C57BL/6NCrl-Cdc42ep3/Mmucd |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cdc42ep5/Cdc42ep5 |
| Background: |
C57BL/6N-Cdc42ep5/Nju |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miyamoto Y |
| Year: |
2007 |
| Journal: |
Exp Cell Res |
| Title: |
Dock6, a Dock-C subfamily guanine nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth. |
| Volume: |
313 |
| Issue: |
4 |
| Pages: |
791-804 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okabe T |
| Year: |
2003 |
| Journal: |
J Biol Chem |
| Title: |
RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling. |
| Volume: |
278 |
| Issue: |
11 |
| Pages: |
9920-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai K |
| Year: |
2007 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
START-GAP3/DLC3 is a GAP for RhoA and Cdc42 and is localized in focal adhesions regulating cell morphology. |
| Volume: |
364 |
| Issue: |
4 |
| Pages: |
783-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yakir-Tamang L |
| Year: |
2009 |
| Journal: |
Mol Biol Cell |
| Title: |
A phosphatidylinositol-transfer protein and phosphatidylinositol-4-phosphate 5-kinase control Cdc42 to regulate the actin cytoskeleton and secretory pathway in yeast. |
| Volume: |
20 |
| Issue: |
15 |
| Pages: |
3583-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Funasaka K |
| Year: |
2010 |
| Journal: |
FEBS J |
| Title: |
Cas utilizes Nck2 to activate Cdc42 and regulate cell polarization during cell migration in response to wound healing. |
| Volume: |
277 |
| Issue: |
17 |
| Pages: |
3502-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sudhaharan T |
| Year: |
2011 |
| Journal: |
PLoS One |
| Title: |
Rho GTPase Cdc42 is a direct interacting partner of Adenomatous Polyposis Coli protein and can alter its cellular localization. |
| Volume: |
6 |
| Issue: |
2 |
| Pages: |
e16603 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1062
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1099
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
965
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
971
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1266
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kneussel M |
| Year: |
2001 |
| Journal: |
Eur J Neurosci |
| Title: |
Distribution of transcripts for the brain-specific GDP/GTP exchange factor collybistin in the developing mouse brain. |
| Volume: |
13 |
| Issue: |
3 |
| Pages: |
487-92 |
|
•
•
•
•
•
|