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Search results 2001 to 2100 out of 2260 for Erbb2

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Type Details Score
Publication
First Author: Reddy HK
Year: 2005
Journal: Cancer Res
Title: Cyclin-dependent kinase 4 expression is essential for neu-induced breast tumorigenesis.
Volume: 65
Issue: 22
Pages: 10174-8
Publication
First Author: Li Y
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells.
Volume: 100
Issue: 26
Pages: 15853-8
Publication
First Author: Wakefield A
Year: 2013
Journal: Cancer Res
Title: Bcl3 selectively promotes metastasis of ERBB2-driven mammary tumors.
Volume: 73
Issue: 2
Pages: 745-55
Strain
Attribute String: congenic, mutant strain, transgenic
Publication
First Author: McHenry PR
Year: 2010
Journal: Breast Cancer Res
Title: P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis.
Volume: 12
Issue: 5
Pages: R73
Publication
First Author: Bridges AE
Year: 2020
Journal: Cancer Res
Title: RAD51AP1 Deficiency Reduces Tumor Growth by Targeting Stem Cell Self-Renewal.
Volume: 80
Issue: 18
Pages: 3855-3866
Publication
First Author: Ciraolo E
Year: 2008
Journal: Sci Signal
Title: Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development.
Volume: 1
Issue: 36
Pages: ra3
Publication
First Author: Homer-Bouthiette C
Year: 2018
Journal: BMC Cancer
Title: Deletion of the murine ortholog of the 8q24 gene desert has anti-cancer effects in transgenic mammary cancer models.
Volume: 18
Issue: 1
Pages: 1233
Publication
First Author: Babu E
Year: 2015
Journal: Biochem J
Title: Deletion of the amino acid transporter Slc6a14 suppresses tumour growth in spontaneous mouse models of breast cancer.
Volume: 469
Issue: 1
Pages: 17-23
Publication
First Author: Zhao Z
Year: 2016
Journal: Cancer Res
Title: In Vivo Visualization and Characterization of Epithelial-Mesenchymal Transition in Breast Tumors.
Volume: 76
Issue: 8
Pages: 2094-2104
Publication  
First Author: Grasso S
Year: 2017
Journal: Nat Commun
Title: The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries.
Volume: 8
Pages: 14797
Publication
First Author: Hao M
Year: 2021
Journal: Dev Cell
Title: Autophagy Blockade Limits HER2+ Breast Cancer Tumorigenesis by Perturbing HER2 Trafficking and Promoting Release Via Small Extracellular Vesicles.
Volume: 56
Issue: 3
Pages: 341-355.e5
Publication  
First Author: Achyut BR
Year: 2020
Journal: Cancer Lett
Title: Oncoprotein GT198 vaccination delays tumor growth in MMTV-PyMT mice.
Volume: 476
Pages: 57-66
Publication
First Author: Koyama H
Year: 2007
Journal: Am J Pathol
Title: Hyperproduction of hyaluronan in neu-induced mammary tumor accelerates angiogenesis through stromal cell recruitment: possible involvement of versican/PG-M.
Volume: 170
Issue: 3
Pages: 1086-99
Publication  
First Author: Manna PR
Year: 2023
Journal: Int J Mol Sci
Title: Expression and Function of StAR in Cancerous and Non-Cancerous Human and Mouse Breast Tissues: New Insights into Diagnosis and Treatment of Hormone-Sensitive Breast Cancer.
Volume: 24
Issue: 1
Publication  
First Author: Sarrio D
Year: 2022
Journal: Front Cell Dev Biol
Title: Gasdermin-B Pro-Tumor Function in Novel Knock-in Mouse Models Depends on the in vivo Biological Context.
Volume: 10
Pages: 813929
Publication
First Author: Goldman SJ
Year: 2011
Journal: PLoS One
Title: Use of the ODD-luciferase transgene for the non-invasive imaging of spontaneous tumors in mice.
Volume: 6
Issue: 3
Pages: e18269
Publication
First Author: Song SJ
Year: 2013
Journal: Cell
Title: MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling.
Volume: 154
Issue: 2
Pages: 311-324
Publication
First Author: Ramachandran S
Year: 2021
Journal: Biochem J
Title: Expression and function of SLC38A5, an amino acid-coupled Na+/H+ exchanger, in triple-negative breast cancer and its relevance to macropinocytosis.
Volume: 478
Issue: 21
Pages: 3957-3976
Publication
First Author: Tosi G
Year: 2024
Journal: Nat Commun
Title: Cancer cell stiffening via CoQ(10) and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer.
Volume: 15
Issue: 1
Pages: 8214
Publication    
First Author: Yeo SK
Year: 2020
Journal: Elife
Title: Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer.
Volume: 9
Publication
First Author: Uribesalgo I
Year: 2019
Journal: EMBO Mol Med
Title: Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy.
Volume: 11
Issue: 8
Pages: e9266
Publication
First Author: Jeselsohn R
Year: 2010
Journal: Cancer Cell
Title: Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis.
Volume: 17
Issue: 1
Pages: 65-76
Publication
First Author: Taverna D
Year: 2005
Journal: Cancer Res
Title: A direct test of potential roles for beta3 and beta5 integrins in growth and metastasis of murine mammary carcinomas.
Volume: 65
Issue: 22
Pages: 10324-9
Publication
First Author: Bui T
Year: 2019
Journal: Cell Rep
Title: Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer.
Volume: 29
Issue: 3
Pages: 589-602.e6
Publication
First Author: Iliopoulos D
Year: 2009
Journal: Sci Signal
Title: MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells.
Volume: 2
Issue: 92
Pages: ra62
Publication
First Author: Feng WW
Year: 2019
Journal: Cell Rep
Title: CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies.
Volume: 29
Issue: 11
Pages: 3405-3420.e5
Publication
First Author: Ramovs V
Year: 2019
Journal: Breast Cancer Res
Title: Absence of integrin α3β1 promotes the progression of HER2-driven breast cancer in vivo.
Volume: 21
Issue: 1
Pages: 63
Publication
First Author: Klover PJ
Year: 2010
Journal: Neoplasia
Title: Loss of STAT1 from mouse mammary epithelium results in an increased Neu-induced tumor burden.
Volume: 12
Issue: 11
Pages: 899-905
Publication
First Author: Meyer DS
Year: 2011
Journal: Cancer Res
Title: Luminal expression of PIK3CA mutant H1047R in the mammary gland induces heterogeneous tumors.
Volume: 71
Issue: 13
Pages: 4344-51
Publication
First Author: Chan CH
Year: 2012
Journal: Cell
Title: The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis.
Volume: 149
Issue: 5
Pages: 1098-111
Publication
First Author: Bienvenu F
Year: 2010
Journal: Nature
Title: Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.
Volume: 463
Issue: 7279
Pages: 374-8
Publication
First Author: Strumane K
Year: 2009
Journal: J Cancer Res Clin Oncol
Title: Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice.
Volume: 135
Issue: 1
Pages: 69-80
Publication
First Author: Brown NE
Year: 2012
Journal: Cancer Res
Title: Cyclin D1 activity regulates autophagy and senescence in the mammary epithelium.
Volume: 72
Issue: 24
Pages: 6477-89
Publication
First Author: Nair HB
Year: 2012
Journal: Horm Cancer
Title: Estrogen receptor-beta mediates the protective effects of aromatase induction in the MMTV-Her-2/neu x aromatase double transgenic mice.
Volume: 3
Issue: 1-2
Pages: 26-36
Publication  
First Author: Goyette MA
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels.
Volume: 118
Issue: 29
Publication
First Author: Patra KC
Year: 2013
Journal: Cancer Cell
Title: Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer.
Volume: 24
Issue: 2
Pages: 213-228
Publication
First Author: Ursini-Siegel J
Year: 2008
Journal: EMBO J
Title: ShcA signalling is essential for tumour progression in mouse models of human breast cancer.
Volume: 27
Issue: 6
Pages: 910-20
Publication
First Author: Ray D
Year: 2007
Journal: Cancer Res
Title: Hemizygous disruption of Cdc25A inhibits cellular transformation and mammary tumorigenesis in mice.
Volume: 67
Issue: 14
Pages: 6605-11
Publication
First Author: Ray D
Year: 2007
Journal: Cancer Res
Title: Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability.
Volume: 67
Issue: 3
Pages: 984-91
Publication
First Author: de Candia P
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Angiogenesis impairment in Id-deficient mice cooperates with an Hsp90 inhibitor to completely suppress HER2/neu-dependent breast tumors.
Volume: 100
Issue: 21
Pages: 12337-42
Publication
First Author: Schreiber C
Year: 2013
Journal: PLoS One
Title: Autochthonous mouse melanoma and mammary tumors do not express the pluripotency genes Oct4 and Nanog.
Volume: 8
Issue: 2
Pages: e57465
Publication
First Author: Utermark T
Year: 2012
Journal: Genes Dev
Title: The p110α and p110β isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis.
Volume: 26
Issue: 14
Pages: 1573-86
Publication
First Author: Bigi A
Year: 2016
Journal: Oncogene
Title: Cyclophilin D counteracts P53-mediated growth arrest and promotes Ras tumorigenesis.
Volume: 35
Issue: 39
Pages: 5132-43
Publication  
First Author: Lyu C
Year: 2021
Journal: JCI Insight
Title: Targeting Gi/o protein-coupled receptor signaling blocks HER2-induced breast cancer development and enhances HER2-targeted therapy.
Volume: 6
Issue: 18
Publication
First Author: Lai J
Year: 2020
Journal: Nat Immunol
Title: Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity.
Volume: 21
Issue: 8
Pages: 914-926
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: Goel S
Year: 2016
Journal: Cancer Cell
Title: Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors.
Volume: 29
Issue: 3
Pages: 255-69
Publication
First Author: Hayworth CR
Year: 2006
Journal: J Neurosci
Title: Induction of neuregulin signaling in mouse schwann cells in vivo mimics responses to denervation.
Volume: 26
Issue: 25
Pages: 6873-84
Publication
First Author: Al-Zahrani KN
Year: 2020
Journal: Oncogene
Title: Loss of the Ste20-like kinase induces a basal/stem-like phenotype in HER2-positive breast cancers.
Volume: 39
Issue: 23
Pages: 4592-4602
Publication
First Author: Thorpe LM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α.
Volume: 114
Issue: 27
Pages: 7095-7100
Publication
First Author: Andrechek ER
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential.
Volume: 106
Issue: 38
Pages: 16387-92
Publication
First Author: Siegel PM
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis.
Volume: 100
Issue: 14
Pages: 8430-5
Genotype
Symbol: Akt2/Akt2 Tg(MMTV-Erbb2)NK1Mul/Tg(MMTV-Erbb2)NK1Mul
Background: involves: 129 * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Esr1/Esr1 Tg(MMTV-Erbb2)NK1Mul/?
Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-Has2)99Nita/? Tg(MMTV-cre)4Mam/? Tg(MMTVneu)202Mul/?
Background: FVB.Cg-Tg(CAG-Has2)99Nita Tg(MMTV-cre)4Mam Tg(MMTVneu)202Mul
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Erbb3/Erbb3<+> Tg(MMTV-Erbb2*)NDL2-5Mul/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Erbb3/Erbb3 Tg(MMTV-Erbb2*)NDL2-5Mul/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ccnd1/Ccnd1 Tg(CAG-cre/Esr1*)5Amc/? Tg(MMTV-Erbb2)NK1Mul/?
Background: involves: 129S2/SvPas * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(MMTV-rtTA)1Lach/? Tg(tetO-ERBB2)#Jjz/?
Background: involves: FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Slc6a14/Slc6a14 Tg(MMTVneu)202Mul/?
Background: involves: FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Nmi/Nmi Tg(KRT14-cre)1Amc/? Tg(MMTVneu)202Mul/?
Background: involves: 129S/SvEv * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Fujita Y
Year: 1994
Journal: Biochem Biophys Res Commun
Title: A novel heparin-binding protein, HBp15, is identified as mammalian ribosomal protein L22.
Volume: 199
Issue: 2
Pages: 706-13
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Kim A
Year: 2005
Journal: Breast Cancer Res
Title: Functional interaction between mouse erbB3 and wild-type rat c-neu in transgenic mouse mammary tumor cells.
Volume: 7
Issue: 5
Pages: R708-18
Publication  
First Author: Mitchell R
Year: 2020
Journal: Neurobiol Dis
Title: ErbB1-dependent signalling and vesicular trafficking in primary afferent nociceptors associated with hypersensitivity in neuropathic pain.
Volume: 142
Pages: 104961
Protein  
Organism: Mus musculus/domesticus
Length:  
Publication
First Author: Floerchinger A
Year: 2021
Journal: Cell Rep
Title: Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging.
Volume: 36
Issue: 11
Pages: 109689
Publication
First Author: Eyermann CE
Year: 2021
Journal: Cell Death Dis
Title: ΔN63 suppresses the ability of pregnancy-identified mammary epithelial cells (PIMECs) to drive HER2-positive breast cancer.
Volume: 12
Issue: 6
Pages: 525
Publication
First Author: Feng Y
Year: 2014
Journal: Cancer Discov
Title: SPSB1 promotes breast cancer recurrence by potentiating c-MET signaling.
Volume: 4
Issue: 7
Pages: 790-803
Publication
First Author: Payne AW
Year: 2014
Journal: Cancer Res
Title: Ceramide kinase promotes tumor cell survival and mammary tumor recurrence.
Volume: 74
Issue: 21
Pages: 6352-63
Publication
First Author: Alvarez JV
Year: 2013
Journal: Cancer Cell
Title: Par-4 downregulation promotes breast cancer recurrence by preventing multinucleation following targeted therapy.
Volume: 24
Issue: 1
Pages: 30-44
Publication  
First Author: Pathania R
Year: 2015
Journal: Nat Commun
Title: DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis.
Volume: 6
Pages: 6910
Publication
First Author: Balavenkatraman KK
Year: 2011
Journal: Mol Cancer Res
Title: Epithelial protein-tyrosine phosphatase 1B contributes to the induction of mammary tumors by HER2/Neu but is not essential for tumor maintenance.
Volume: 9
Issue: 10
Pages: 1377-84
Publication
First Author: Zhang Q
Year: 2011
Journal: Cancer Res
Title: Cyclin D3 compensates for the loss of cyclin D1 during ErbB2-induced mammary tumor initiation and progression.
Volume: 71
Issue: 24
Pages: 7513-24
Publication
First Author: Landis MW
Year: 2006
Journal: Cancer Cell
Title: Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis.
Volume: 9
Issue: 1
Pages: 13-22
Publication
First Author: Zhang Y
Year: 2024
Journal: Nat Immunol
Title: Tumor editing suppresses innate and adaptive antitumor immunity and is reversed by inhibiting DNA methylation.
Volume: 25
Issue: 10
Pages: 1858-1870
Publication
First Author: Nie L
Year: 2019
Journal: Nat Commun
Title: CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer.
Volume: 10
Issue: 1
Pages: 5114
Publication
First Author: Bosch-Marcé M
Year: 2011
Journal: Hum Mol Genet
Title: Increased IGF-1 in muscle modulates the phenotype of severe SMA mice.
Volume: 20
Issue: 9
Pages: 1844-53
Publication
First Author: González-Martín A
Year: 2011
Journal: Cancer Res
Title: Maximal T cell-mediated antitumor responses rely upon CCR5 expression in both CD4(+) and CD8(+) T cells.
Volume: 71
Issue: 16
Pages: 5455-66
Publication
First Author: Trimboli AJ
Year: 2009
Journal: Nature
Title: Pten in stromal fibroblasts suppresses mammary epithelial tumours.
Volume: 461
Issue: 7267
Pages: 1084-91
Publication
First Author: Mikaelian I
Year: 2004
Journal: Breast Cancer Res
Title: Proteotypic classification of spontaneous and transgenic mammary neoplasms.
Volume: 6
Issue: 6
Pages: R668-79
Publication
First Author: Fu R
Year: 2019
Journal: Nat Commun
Title: A ZEB1/p53 signaling axis in stromal fibroblasts promotes mammary epithelial tumours.
Volume: 10
Issue: 1
Pages: 3210
Publication
First Author: Kouros-Mehr H
Year: 2008
Journal: Cancer Cell
Title: GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model.
Volume: 13
Issue: 2
Pages: 141-52
Publication
First Author: Vega-Rubín-de-Celis S
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Increased autophagy blocks HER2-mediated breast tumorigenesis.
Volume: 115
Issue: 16
Pages: 4176-4181
Publication
First Author: Fischer KR
Year: 2015
Journal: Nature
Title: Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance.
Volume: 527
Issue: 7579
Pages: 472-6
Publication
First Author: Dibra D
Year: 2024
Journal: Sci Adv
Title: Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo.
Volume: 10
Issue: 7
Pages: eadk1835
Publication
First Author: Dibra D
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Triple-negative breast tumors are dependent on mutant p53 for growth and survival.
Volume: 120
Issue: 34
Pages: e2308807120
Publication
First Author: Wu J
Year: 2022
Journal: Mol Cancer Res
Title: Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner.
Volume: 20
Issue: 8
Pages: 1233-1246
Publication
First Author: Khalil S
Year: 2012
Journal: PLoS One
Title: Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse.
Volume: 7
Issue: 3
Pages: e33421
Publication
First Author: Koyama H
Year: 2008
Journal: Am J Pathol
Title: Significance of tumor-associated stroma in promotion of intratumoral lymphangiogenesis: pivotal role of a hyaluronan-rich tumor microenvironment.
Volume: 172
Issue: 1
Pages: 179-93
Publication
First Author: Pruitt HC
Year: 2018
Journal: Oncogene
Title: Conditional knockout of N-Myc and STAT interactor disrupts normal mammary development and enhances metastatic ability of mammary tumors.
Volume: 37
Issue: 12
Pages: 1610-1623
Publication
First Author: Cheung KJ
Year: 2013
Journal: Cell
Title: Collective invasion in breast cancer requires a conserved basal epithelial program.
Volume: 155
Issue: 7
Pages: 1639-51
Publication
First Author: Cianciaruso C
Year: 2019
Journal: Cell Rep
Title: Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles.
Volume: 27
Issue: 10
Pages: 3062-3080.e11
Publication
First Author: Maroulakou IG
Year: 2007
Journal: Cancer Res
Title: Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice.
Volume: 67
Issue: 1
Pages: 167-77
Publication
First Author: Rowald K
Year: 2016
Journal: Cell Rep
Title: Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth.
Volume: 15
Issue: 12
Pages: 2679-91
Publication
First Author: Domingues PH
Year: 2017
Journal: Cancer Res
Title: Cellular Prion Protein PrPC and Ecto-5'-Nucleotidase Are Markers of the Cellular Stress Response to Aneuploidy.
Volume: 77
Issue: 11
Pages: 2914-2926
Publication
First Author: Pan F
Year: 2023
Journal: Cell Death Dis
Title: FOXM1 is critical for the fitness recovery of chromosomally unstable cells.
Volume: 14
Issue: 7
Pages: 430
Publication
First Author: Podmore L
Year: 2023
Journal: Cell Rep
Title: Insulin receptor loss impairs mammary tumorigenesis in mice.
Volume: 42
Issue: 11
Pages: 113251