| Type |
Details |
Score |
| Allele |
| Name: |
fibroblast growth factor receptor 1; targeted mutation 1, Philip Leder |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
fibroblast growth factor receptor 1; targeted mutation 2.1, Chu-Xia Deng |
| Allele Type: |
Targeted |
| Attribute String: |
Humanized sequence |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, targeted mutation |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fgfr1op2/Fgfr1op2 |
| Background: |
C57BL/6N-Fgfr1op2/MbpMmucd |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Allele |
| Name: |
fibroblast growth factor receptor 2; targeted mutation 2.3, Clive Dickson |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fgfr1/Fgfr1 |
| Background: |
involves: 129S4/SvJae * NIH Black Swiss |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fgfr1/Fgfr1<+> |
| Background: |
D2.129S6(Cg)-Fgfr1 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Luyang Yu |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Epitope tag, Inserted expressed sequence |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Murcia-Belmonte V |
| Year: |
2010 |
| Journal: |
J Neurochem |
| Title: |
Biochemical dissection of Anosmin-1 interaction with FGFR1 and components of the extracellular matrix. |
| Volume: |
115 |
| Issue: |
5 |
| Pages: |
1256-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Persaud A |
| Year: |
2011 |
| Journal: |
EMBO J |
| Title: |
Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function. |
| Volume: |
30 |
| Issue: |
16 |
| Pages: |
3259-73 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fgfr1op2/Fgfr1op2<+> |
| Background: |
C57BL/6N-Fgfr1op2/MbpMmucd |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fgfr2/Fgfr2<+> |
| Background: |
involves: 129 * C57BL/6 * FVB/N |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guasch G |
| Year: |
2000 |
| Journal: |
Blood |
| Title: |
FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33). |
| Volume: |
95 |
| Issue: |
5 |
| Pages: |
1788-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kiselyov VV |
| Year: |
2003 |
| Journal: |
Structure |
| Title: |
Structural basis for a direct interaction between FGFR1 and NCAM and evidence for a regulatory role of ATP. |
| Volume: |
11 |
| Issue: |
6 |
| Pages: |
691-701 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
660
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
529
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
646
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
649
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 4775, Jeffrey Rosen |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Luyang Yu |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Epitope tag, Inserted expressed sequence |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, Wallace L McKeenan |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schwertfeger KL |
| Year: |
2006 |
| Journal: |
Cancer Res |
| Title: |
A critical role for the inflammatory response in a mouse model of preneoplastic progression. |
| Volume: |
66 |
| Issue: |
11 |
| Pages: |
5676-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bohrer LR |
| Year: |
2014 |
| Journal: |
Cancer Res |
| Title: |
Activation of the FGFR-STAT3 pathway in breast cancer cells induces a hyaluronan-rich microenvironment that licenses tumor formation. |
| Volume: |
74 |
| Issue: |
1 |
| Pages: |
374-86 |
|
•
•
•
•
•
|
| Allele |
| Name: |
collagen, type I, alpha 1; targeted mutation 15, The Netherlands Cancer Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE41260 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
410
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
444
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, Pei-San Tsai |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion, Wallace L McKeehan |
| Allele Type: |
Transgenic |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion, David M Ornitz |
| Allele Type: |
Transgenic |
| Attribute String: |
Constitutively active, Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
fibroblast growth factor receptor 1; targeted mutation 11.1, Philippe Soriano |
| Allele Type: |
Targeted |
| Attribute String: |
No functional change, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
fibroblast growth factor receptor 1; targeted mutation 12.1, Philippe Soriano |
| Allele Type: |
Targeted |
| Attribute String: |
No functional change, Reporter |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dong S |
| Year: |
2016 |
| Journal: |
Cancer Cell |
| Title: |
A New Role for Lyn in the CLL Microenvironment. |
| Volume: |
30 |
| Issue: |
4 |
| Pages: |
511-512 |
|
•
•
•
•
•
|
| Allele |
| Name: |
fibroblast growth factor receptor 1; targeted mutation 14.1, Philippe Soriano |
| Allele Type: |
Targeted |
| Attribute String: |
Epitope tag |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
fibroblast growth factor receptor 1; targeted mutation 15.1, Philippe Soriano |
| Allele Type: |
Targeted |
| Attribute String: |
Epitope tag |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Arr2/Pbsn-FGFR1K656E)1Wmck/? |
| Background: |
involves: FVB |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
245
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ferone G |
| Year: |
2016 |
| Journal: |
Cancer Cell |
| Title: |
SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin. |
| Volume: |
30 |
| Issue: |
4 |
| Pages: |
519-532 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
333
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
427
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
315
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tsai PS |
| Year: |
2005 |
| Journal: |
Mol Endocrinol |
| Title: |
Targeted expression of a dominant-negative fibroblast growth factor (FGF) receptor in gonadotropin-releasing hormone (GnRH) neurons reduces FGF responsiveness and the size of GnRH neuronal population. |
| Volume: |
19 |
| Issue: |
1 |
| Pages: |
225-36 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
targeted mutation, mutant strain, coisogenic |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Gnrh1-Fgfr1)1Tsai/Tg(Gnrh1-Fgfr1)1Tsai |
| Background: |
involves: C57BL/6J * DBA/2J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fgfr1/Fgfr1<+> |
| Background: |
129S4/SvJaeSor-Fgfr1 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
162
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
264
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
209
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Armand AS |
| Year: |
2006 |
| Journal: |
Biochim Biophys Acta |
| Title: |
FGF6 in myogenesis. |
| Volume: |
1763 |
| Issue: |
8 |
| Pages: |
773-8 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
695
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
850
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
251
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
207
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
202
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
154
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
211
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
216
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
155
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
208
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Reilly JF |
| Year: |
2000 |
| Journal: |
J Biol Chem |
| Title: |
Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14. Characterization of a new receptor binding partner. |
| Volume: |
275 |
| Issue: |
11 |
| Pages: |
7771-8 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Pbsn-FGFR1*K656E)#Wmck/? |
| Background: |
involves: FVB |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Arr2/Pbsn-FGFR1K656E)1Wmck/? Tg(Pbsn-FGFR2_iiib*)#Ng/? |
| Background: |
involves: FVB |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
822
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
268
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
208
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Davidson D |
| Year: |
2005 |
| Journal: |
J Biol Chem |
| Title: |
Fibroblast growth factor (FGF) 18 signals through FGF receptor 3 to promote chondrogenesis. |
| Volume: |
280 |
| Issue: |
21 |
| Pages: |
20509-15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Patra D |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. |
| Volume: |
9 |
| Issue: |
8 |
| Pages: |
e105674 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
751
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
492
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1014
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Keegan K |
| Year: |
1993 |
| Journal: |
Cytogenet Cell Genet |
| Title: |
The fibroblast growth factor receptor 3 gene (FGFR3) is assigned to human chromosome 4. |
| Volume: |
62 |
| Issue: |
2-3 |
| Pages: |
172-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yousaf R |
| Year: |
2018 |
| Journal: |
J Clin Invest |
| Title: |
Modifier variant of METTL13 suppresses human GAB1-associated profound deafness. |
| Volume: |
128 |
| Issue: |
4 |
| Pages: |
1509-1522 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
207
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
124
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
83
 |
| Fragment?: |
true |
|
•
•
•
•
•
|