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Search results 2001 to 2100 out of 12470 for Impact

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Type Details Score
Publication
37858461 | J:342556
First Author: Feng Y
Year: 2023
Journal: Cell Rep
Title: Stress regulates Alzheimer's disease progression via selective enrichment of CD8(+) T cells.
Volume: 42
Issue: 10
Pages: 113313
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Publication
25088770 | J:263583
First Author: Oliphant CJ
Year: 2014
Journal: Immunity
Title: MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion.
Volume: 41
Issue: 2
Pages: 283-95
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Publication
26523868 | J:234441
First Author: Halim TY
Year: 2016
Journal: Nat Immunol
Title: Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responses.
Volume: 17
Issue: 1
Pages: 57-64
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Publication
38413714 | J:354545
First Author: Dong H
Year: 2024
Journal: Nat Cancer
Title: Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity.
Volume: 5
Issue: 4
Pages: 601-624
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Publication
29907525 | J:267611
First Author: Halim TYF
Year: 2018
Journal: Immunity
Title: Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells.
Volume: 48
Issue: 6
Pages: 1195-1207.e6
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Publication
29183988 | J:257625
First Author: Harly C
Year: 2018
Journal: J Exp Med
Title: Development and differentiation of early innate lymphoid progenitors.
Volume: 215
Issue: 1
Pages: 249-262
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Publication
24509509 | J:209928
First Author: Schwickert TA
Year: 2014
Journal: Nat Immunol
Title: Stage-specific control of early B cell development by the transcription factor Ikaros.
Volume: 15
Issue: 3
Pages: 283-93
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Publication
35263149 | J:326756
First Author: Schwartz C
Year: 2022
Journal: Sci Transl Med
Title: Innate PD-L1 limits T cell-mediated adipose tissue inflammation and ameliorates diet-induced obesity.
Volume: 14
Issue: 635
Pages: eabj6879
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Publication
28514688 | J:258946
First Author: Miyazaki M
Year: 2017
Journal: Immunity
Title: The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development.
Volume: 46
Issue: 5
Pages: 818-834.e4
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Publication
37285842 | J:337870
First Author: Ferreira ACF
Year: 2023
Journal: Immunity
Title: Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation.
Volume: 56
Issue: 7
Pages: 1468-1484.e7
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Publication
31248899 | J:336874
First Author: Rana BMJ
Year: 2019
Journal: J Exp Med
Title: A stromal cell niche sustains ILC2-mediated type-2 conditioning in adipose tissue.
Volume: 216
Issue: 9
Pages: 1999-2009
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Publication
37300435 | J:337403
     
First Author: Murray GC
Year: 2023
Journal: G3 (Bethesda)
Title: An allelic series of spontaneous Rorb mutant mice exhibit a gait phenotype, changes in retina morphology and behavior, and gene expression signatures associated with the unfolded protein response.
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Publication
11955625 | J:76235
First Author: Sato H
Year: 2002
Journal: Biochim Biophys Acta
Title: ik3-2, a relative to ik3-1/cables, is associated with cdk3, cdk5, and c-abl.
Volume: 1574
Issue: 2
Pages: 157-63
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Publication
15363845 | J:92984
 
First Author: Suzuki K
Year: 2004
Journal: Gene
Title: Molecular evolution of epididymal lipocalin genes localized on mouse chromosome 2.
Volume: 339
Pages: 49-59
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HT Experiment
E-GEOD-5317 | Transcription profiling of mouse day 0 versus day 1 involuting mammary gland
Series Id: GSE5317
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
GSE79087 | REV-ERBalpha influences stability and nuclear localization of the glucocorticoid receptor
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
11809823 | J:168212
First Author: Sharer JD
Year: 2002
Journal: Mol Biol Cell
Title: ARL2 and BART enter mitochondria and bind the adenine nucleotide transporter.
Volume: 13
Issue: 1
Pages: 71-83
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Protein
Q9QWF0
Organism: Mus musculus/domesticus
Length: 911  
Fragment?: false
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Publication
7680958 | J:43378
First Author: Zhou A
Year: 1993
Journal: Cell
Title: Expression cloning of 2-5A-dependent RNAase: a uniquely regulated mediator of interferon action.
Volume: 72
Issue: 5
Pages: 753-65
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Protein
Q3T9T6
Organism: Mus musculus/domesticus
Length: 227  
Fragment?: false
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Protein
D3YXE4
Organism: Mus musculus/domesticus
Length: 60  
Fragment?: true
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Publication
11906833 | -
First Author: Jakoby M
Year: 2002
Journal: Trends Plant Sci
Title: bZIP transcription factors in Arabidopsis.
Volume: 7
Issue: 3
Pages: 106-11
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Protein Domain
IPR002552 | Spike_S2_CoV
Type: Domain
Description: The type I glycoprotein S of Coronavirus, trimers of which constitute the typical viral spikes, is assembled into virions through noncovalent interactions with the M protein. The spike glycoprotein is translated as a large polypeptide that is subsequently cleaved to S1 () and S2 []. The cleavage of S can occur at two distinct sites: S2 or S2' []. The spike is present in two very different forms: pre-fusion (the form on mature virions) and post-fusion (the form after membrane fusion has been completed). The spike is cleaved sequentially by host proteases at two sites: first at the S1/S2 boundary (i.e. S1/S2 site) and second within S2 (i.e. S2' site). After the cleavages, S1 dissociates from S2, allowing S2 to transition to the post-fusion structure []. Both chimeric S proteins appeared to cause cell fusion when expressed individually, suggesting that they were biologically fully active []. The spike is a type I membrane glycoprotein that possesses a conserved transmembrane anchor and an unusual cysteine-rich (cys) domain that bridges the putative junction of the anchor and the cytoplasmic tail [].SARS-CoV S is largely uncleaved after biosynthesis. It can be later processed by endosomal cathepsin L, trypsin, thermolysin, and elastase, which are shown to induce syncytia formation and virus entry. Other proteases that are of potential biological relevance in potentiating SARS-CoV S include TMPRSS2, TMPRSS11a, and HAT which are localized on the cell surface and are highly expressed in the human airway []. The furin-like S2' cleavage site at KR/SF with P1 and P2 basic residues and a P2' hydrophobic Phe downstream of the IFP is identical between the SARS-CoV-2 and SARS-CoV. One or more furin-like enzymes would cleave the S2' site at KR/SF [, ]. Deletion of SARS-CoV-2 furin cleavage site suggests that it may not be required for viral entry but may affect replication kinetics and altered sites have been still seen proteolytically cleaved. Several substitutions within the S2' cleavage domain of SARS-COV-2 have been reported, including P812L/S/T, S813I/G, F817L, I818S/V, but further experimental study of their consequences and the replication properties of the altered viruses are required to understand the role of furin cleavage in SARS-CoV-2 infection and virulence []. The S2 subunit normally contains multiple key components, including one or more fusion peptides (FP), a second proteolytic site (S2') and two conserved heptad repeats (HRs), driving membrane penetration and virus-cell fusion. The HRs can trimerize into a coiled-coil structure built of three HR1-HR2 helical hairpins presenting as a canonical six-helix bundle and drag the virus envelope and the host cell bilayer into close proximity, preparing for fusion to occur []. The fusion core is composed of HR1 and HR2 and at least three membranotropic regions that are denoted as the fusion peptide (FP), internal fusion peptide (IFP), and pretransmembrane domain (PTM). The HR regions are further flanked by the three membranotropic components. Both FP and IFP are located upstream of HR1, while PTM is distally downstream of HR2 and directly precedes the transmembrane domain of SARS-CoV S. All of these three components are able to partition into the phospholipid bilayer to disturb membrane integrity. []. During the pandemic, many conservative amino acid changes in FP segment of SARS-CoV-2 have been reported (i.e., L821I, L822F, K825R, V826L, T827I, L828P, A829T, D830G/A, A831V/S/T, G832C/S, F833S, I834T), although their impact is not known as the active conformation and mode of insertion of SARS-CoV-2 fusion peptide have not been experimentally characterised. Differences in HR1 sequences between SARS-CoV and SARS-CoV-2 suggest that SARS-CoV-2 HR2 makes stronger interactions with HR1. However, the substitutions observed in the solvent accessible surface of the HR1 domain (e.g., D936Y, S943P, S939F) of SARS-CoV-2 do not seem to be involved in stabilizing interactions with HR2. Substitutions in HR2 (e.g., K1073N, V1176F) or the TM or cytoplasmic tail domains have also been observed, but further experimental work is required to determine the effects of these changes [].
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Protein
P10922
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: false
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Protein
P43275
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: false
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Protein
P15864
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: false
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Protein
Q3TEA8
Organism: Mus musculus/domesticus
Length: 554  
Fragment?: false
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Protein
P43277
Organism: Mus musculus/domesticus
Length: 221  
Fragment?: false
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Protein
P43274
Organism: Mus musculus/domesticus
Length: 219  
Fragment?: false
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Protein
Q07133
Organism: Mus musculus/domesticus
Length: 208  
Fragment?: false
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Protein
P43276
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: false
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Protein
I7HFT9
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: false
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Protein
Q3B7C1
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: true
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Protein
Z4YKB8
Organism: Mus musculus/domesticus
Length: 554  
Fragment?: false
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Protein
Q3UXH2
Organism: Mus musculus/domesticus
Length: 136  
Fragment?: true
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Protein
Z4YKA3
Organism: Mus musculus/domesticus
Length: 516  
Fragment?: false
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Protein
A2AM63
Organism: Mus musculus/domesticus
Length: 208  
Fragment?: true
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Protein
Q3U292
Organism: Mus musculus/domesticus
Length: 221  
Fragment?: false
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Protein
Q8C1Y3
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
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Protein
A2AM65
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: true
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Protein
Q1WWK3
Organism: Mus musculus/domesticus
Length: 222  
Fragment?: true
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Protein
Q3U4Y0
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: false
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Protein
Q5SZA3
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: false
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Protein
Q80ZM5
Organism: Mus musculus/domesticus
Length: 188  
Fragment?: false
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Protein
Q149Z9
Organism: Mus musculus/domesticus
Length: 221  
Fragment?: false
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Publication
28751364 | J:244975
First Author: Kriebs A
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity.
Volume: 114
Issue: 33
Pages: 8776-8781
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Publication
22327075 | J:181846
First Author: Swiecki M
Year: 2012
Journal: J Immunol
Title: Cutting edge: paradoxical roles of BST2/tetherin in promoting type I IFN response and viral infection.
Volume: 188
Issue: 6
Pages: 2488-92
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Publication
25200183 | J:272987
First Author: Ryu D
Year: 2014
Journal: Cell Metab
Title: A SIRT7-dependent acetylation switch of GABPβ1 controls mitochondrial function.
Volume: 20
Issue: 5
Pages: 856-869
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Publication
27105113 | J:243518
First Author: Goudarzi A
Year: 2016
Journal: Mol Cell
Title: Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters.
Volume: 62
Issue: 2
Pages: 169-80
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Publication
32460033 | J:291970
First Author: Takemoto K
Year: 2020
Journal: Cell Rep
Title: Meiosis-Specific C19orf57/4930432K21Rik/BRME1 Modulates Localization of RAD51 and DMC1 to DSBs in Mouse Meiotic Recombination.
Volume: 31
Issue: 8
Pages: 107686
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Publication
26359501 | J:243471
First Author: Cattin ME
Year: 2015
Journal: J Biol Chem
Title: Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptation.
Volume: 290
Issue: 44
Pages: 26699-714
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Publication
12433368 | J:85616
First Author: Priatel JJ
Year: 2002
Journal: Immunity
Title: RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation.
Volume: 17
Issue: 5
Pages: 617-27
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Publication
32231671 | J:306211
 
First Author: Beck S
Year: 2020
Journal: Front Immunol
Title: ANP32B Deficiency Protects Mice From Lethal Influenza A Virus Challenge by Dampening the Host Immune Response.
Volume: 11
Pages: 450
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Publication
27745970 | J:243512
First Author: Geiger R
Year: 2016
Journal: Cell
Title: L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.
Volume: 167
Issue: 3
Pages: 829-842.e13
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Publication
18286643 | J:273546
First Author: Gunnarson E
Year: 2008
Journal: Glia
Title: Identification of a molecular target for glutamate regulation of astrocyte water permeability.
Volume: 56
Issue: 6
Pages: 587-96
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Publication
25232112 | J:216499
First Author: Wang SH
Year: 2014
Journal: J Neurosci
Title: Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.
Volume: 34
Issue: 38
Pages: 12745-61
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Publication
21982743 | J:179646
First Author: Patwari P
Year: 2011
Journal: Cell Metab
Title: The arrestin domain-containing 3 protein regulates body mass and energy expenditure.
Volume: 14
Issue: 5
Pages: 671-83
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Publication
20368432 | J:159285
First Author: Olson DP
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake.
Volume: 107
Issue: 16
Pages: 7598-603
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Publication
25784538 | J:221875
 
First Author: Mignogna ML
Year: 2015
Journal: Nat Commun
Title: The intellectual disability protein RAB39B selectively regulates GluA2 trafficking to determine synaptic AMPAR composition.
Volume: 6
Pages: 6504
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Publication
32862441 | J:298767
First Author: Dobenecker MW
Year: 2020
Journal: FEBS Lett
Title: The catalytic domain of the histone methyltransferase NSD2/MMSET is required for the generation of B1 cells in mice.
Volume: 594
Issue: 20
Pages: 3324-3337
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Publication
26194095 | J:224449
 
First Author: Graham DB
Year: 2015
Journal: Nat Commun
Title: Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst.
Volume: 6
Pages: 7838
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Publication
19528298 | J:150420
First Author: Li Y
Year: 2009
Journal: J Cell Biol
Title: HUMMR, a hypoxia- and HIF-1alpha-inducible protein, alters mitochondrial distribution and transport.
Volume: 185
Issue: 6
Pages: 1065-81
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Publication
27796300 | J:242633
 
First Author: Iwata H
Year: 2016
Journal: Nat Commun
Title: PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation.
Volume: 7
Pages: 12849
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Publication
27524497 | J:236984
First Author: Murga M
Year: 2016
Journal: Mol Cell
Title: POLD3 Is Haploinsufficient for DNA Replication in Mice.
Volume: 63
Issue: 5
Pages: 877-83
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Publication
21209208 | J:167848
First Author: Reich A
Year: 2011
Journal: J Neurosci
Title: Fas/CD95 regulatory protein Faim2 is neuroprotective after transient brain ischemia.
Volume: 31
Issue: 1
Pages: 225-33
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Publication
26833026 | J:233036
First Author: Wang B
Year: 2016
Journal: Cell Metab
Title: Intestinal Phospholipid Remodeling Is Required for Dietary-Lipid Uptake and Survival on a High-Fat Diet.
Volume: 23
Issue: 3
Pages: 492-504
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Publication
26882873 | J:234743
 
First Author: Doi M
Year: 2016
Journal: Nat Commun
Title: Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour.
Volume: 7
Pages: 10583
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Publication
27508872 | J:251899
First Author: Khetarpal SA
Year: 2016
Journal: Cell Metab
Title: Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents.
Volume: 24
Issue: 2
Pages: 234-45
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Publication
27178841 | J:260533
First Author: Behrens J
Year: 2016
Journal: Eur J Cell Biol
Title: Coronin 1C-free primary mouse fibroblasts exhibit robust rearrangements in the orientation of actin filaments, microtubules and intermediate filaments.
Volume: 95
Issue: 8
Pages: 239-51
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Publication
11786910 | J:73753
First Author: Wallenius V
Year: 2002
Journal: Nat Med
Title: Interleukin-6-deficient mice develop mature-onset obesity.
Volume: 8
Issue: 1
Pages: 75-9
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Publication
24837677 | J:215244
First Author: Preußner M
Year: 2014
Journal: Mol Cell
Title: Rhythmic U2af26 alternative splicing controls PERIOD1 stability and the circadian clock in mice.
Volume: 54
Issue: 4
Pages: 651-62
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Publication
19948886 | J:156507
First Author: Hirschberg A
Year: 2010
Journal: Mol Cell Biol
Title: Gene deletion mutants reveal a role for semaphorin receptors of the plexin-B family in mechanisms underlying corticogenesis.
Volume: 30
Issue: 3
Pages: 764-80
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Publication
15843560 | J:98403
First Author: Zhu M
Year: 2005
Journal: J Immunol
Title: Negative regulation of lymphocyte activation by the adaptor protein LAX.
Volume: 174
Issue: 9
Pages: 5612-9
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Publication
10839463 | J:66341
First Author: Muntau AC
Year: 2000
Journal: Biol Chem
Title: Genomic organization, expression analysis, and chromosomal localization of the mouse PEX3 gene encoding a peroxisomal assembly protein.
Volume: 381
Issue: 4
Pages: 337-42
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Publication
24656816 | J:211827
First Author: Pan H
Year: 2014
Journal: Cell Rep
Title: Negative elongation factor controls energy homeostasis in cardiomyocytes.
Volume: 7
Issue: 1
Pages: 79-85
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Publication
10777580 | J:61767
First Author: Boehmelt G
Year: 2000
Journal: J Biol Chem
Title: Cloning and characterization of the murine glucosamine-6-phosphate acetyltransferase EMeg32. Differential expression and intracellular membrane association.
Volume: 275
Issue: 17
Pages: 12821-32
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Publication
11136708 | J:66943
First Author: Blanco G
Year: 2001
Journal: Hum Mol Genet
Title: The kyphoscoliosis (ky) mouse is deficient in hypertrophic responses and is caused by a mutation in a novel muscle-specific protein.
Volume: 10
Issue: 1
Pages: 9-16
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Publication
29996098 | J:271270
First Author: Deng W
Year: 2018
Journal: Cell Rep
Title: The Circadian Clock Controls Immune Checkpoint Pathway in Sepsis.
Volume: 24
Issue: 2
Pages: 366-378
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Publication
19401332 | J:150487
First Author: Huang Y
Year: 2009
Journal: J Cell Sci
Title: The collagen receptor DDR1 regulates cell spreading and motility by associating with myosin IIA.
Volume: 122
Issue: Pt 10
Pages: 1637-46
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Publication
23785158 | J:199640
First Author: Schmid T
Year: 2013
Journal: J Neurosci
Title: Loss of NSCL-2 in gonadotropin releasing hormone neurons leads to reduction of pro-opiomelanocortin neurons in specific hypothalamic nuclei and causes visceral obesity.
Volume: 33
Issue: 25
Pages: 10459-70
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Publication
27088444 | J:236888
 
First Author: O'Leary CE
Year: 2016
Journal: Nat Commun
Title: Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells.
Volume: 7
Pages: 11226
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Publication
26668358 | J:228287
First Author: Ogasawara D
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition.
Volume: 113
Issue: 1
Pages: 26-33
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Publication
20453062 | J:161320
First Author: Aguado C
Year: 2010
Journal: Hum Mol Genet
Title: Laforin, the most common protein mutated in Lafora disease, regulates autophagy.
Volume: 19
Issue: 14
Pages: 2867-76
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Publication
30297459 | J:293083
 
First Author: Li ML
Year: 2019
Journal: Mol Cell Biol
Title: Phosphorylation of TIP60 Suppresses 53BP1 Localization at DNA Damage Sites.
Volume: 39
Issue: 1
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Publication
20871598 | J:165573
First Author: Depianto D
Year: 2010
Journal: Nat Genet
Title: Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin.
Volume: 42
Issue: 10
Pages: 910-4
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Publication
24813610 | J:214397
First Author: Alpatov R
Year: 2014
Journal: Cell
Title: A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response.
Volume: 157
Issue: 4
Pages: 869-81
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Publication
26575286 | J:228054
 
First Author: Martin EA
Year: 2015
Journal: Elife
Title: The intellectual disability gene Kirrel3 regulates target-specific mossy fiber synapse development in the hippocampus.
Volume: 4
Pages: e09395
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Publication
32839608 | J:301637
First Author: Ng SS
Year: 2020
Journal: Nat Immunol
Title: The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation.
Volume: 21
Issue: 10
Pages: 1205-1218
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Publication
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