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Search results 2001 to 2100 out of 8321 for Src

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Hits by Pathway

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Hits by Strain

Type Details Score
Allele
Skap2<Gt(OST31022)Lex> | MGI:4151057
 
Name: src family associated phosphoprotein 2; gene trap OST31022, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST31465)Lex> | MGI:4151353
 
Name: src family associated phosphoprotein 1; gene trap OST31465, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST36493)Lex> | MGI:4154544
 
Name: src family associated phosphoprotein 2; gene trap OST36493, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST39355)Lex> | MGI:4156287
 
Name: src family associated phosphoprotein 2; gene trap OST39355, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST43394)Lex> | MGI:4158611
 
Name: src family associated phosphoprotein 2; gene trap OST43394, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST50794)Lex> | MGI:4161739
 
Name: src family associated phosphoprotein 2; gene trap OST50794, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST54889)Lex> | MGI:4163826
 
Name: src family associated phosphoprotein 2; gene trap OST54889, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST59163)Lex> | MGI:4166564
 
Name: src family associated phosphoprotein 2; gene trap OST59163, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST65741)Lex> | MGI:4170742
 
Name: src family associated phosphoprotein 2; gene trap OST65741, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST76581)Lex> | MGI:4174907
 
Name: src family associated phosphoprotein 1; gene trap OST76581, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST78414)Lex> | MGI:4175702
 
Name: src family associated phosphoprotein 2; gene trap OST78414, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST78362)Lex> | MGI:4175679
 
Name: src family associated phosphoprotein 2; gene trap OST78362, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Srcin1<Gt(OST106332)Lex> | MGI:4185790
 
Name: SRC kinase signaling inhibitor 1; gene trap OST106332, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST111779)Lex> | MGI:4188196
 
Name: src family associated phosphoprotein 1; gene trap OST111779, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST122228)Lex> | MGI:4193165
 
Name: src family associated phosphoprotein 1; gene trap OST122228, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST122230)Lex> | MGI:4193167
 
Name: src family associated phosphoprotein 1; gene trap OST122230, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST122239)Lex> | MGI:4193175
 
Name: src family associated phosphoprotein 1; gene trap OST122239, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST122316)Lex> | MGI:4193248
 
Name: src family associated phosphoprotein 1; gene trap OST122316, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST122318)Lex> | MGI:4193250
 
Name: src family associated phosphoprotein 1; gene trap OST122318, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST122321)Lex> | MGI:4193253
 
Name: src family associated phosphoprotein 1; gene trap OST122321, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST122266)Lex> | MGI:4193200
 
Name: src family associated phosphoprotein 1; gene trap OST122266, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST122349)Lex> | MGI:4193275
 
Name: src family associated phosphoprotein 1; gene trap OST122349, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST122350)Lex> | MGI:4193276
 
Name: src family associated phosphoprotein 1; gene trap OST122350, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST122285)Lex> | MGI:4193218
 
Name: src family associated phosphoprotein 1; gene trap OST122285, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST122289)Lex> | MGI:4193222
 
Name: src family associated phosphoprotein 1; gene trap OST122289, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST122399)Lex> | MGI:4193319
 
Name: src family associated phosphoprotein 1; gene trap OST122399, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST122360)Lex> | MGI:4193285
 
Name: src family associated phosphoprotein 1; gene trap OST122360, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST122408)Lex> | MGI:4193328
 
Name: src family associated phosphoprotein 1; gene trap OST122408, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST132243)Lex> | MGI:4198263
 
Name: src family associated phosphoprotein 2; gene trap OST132243, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST135081)Lex> | MGI:4199525
 
Name: src family associated phosphoprotein 2; gene trap OST135081, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST137387)Lex> | MGI:4200507
 
Name: src family associated phosphoprotein 1; gene trap OST137387, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST138415)Lex> | MGI:4200966
 
Name: src family associated phosphoprotein 2; gene trap OST138415, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST166400)Lex> | MGI:4211515
 
Name: src family associated phosphoprotein 2; gene trap OST166400, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST172351)Lex> | MGI:4214464
 
Name: src family associated phosphoprotein 2; gene trap OST172351, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST174038)Lex> | MGI:4215410
 
Name: src family associated phosphoprotein 2; gene trap OST174038, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST178160)Lex> | MGI:4217200
 
Name: src family associated phosphoprotein 2; gene trap OST178160, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST184274)Lex> | MGI:4219954
 
Name: src family associated phosphoprotein 2; gene trap OST184274, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST198492)Lex> | MGI:4227786
 
Name: src family associated phosphoprotein 2; gene trap OST198492, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST211889)Lex> | MGI:4234562
 
Name: src family associated phosphoprotein 1; gene trap OST211889, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST230789)Lex> | MGI:4242334
 
Name: src family associated phosphoprotein 1; gene trap OST230789, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST233060)Lex> | MGI:4243308
 
Name: src family associated phosphoprotein 2; gene trap OST233060, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST265980)Lex> | MGI:4256845
 
Name: src family associated phosphoprotein 2; gene trap OST265980, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Srcin1<Gt(OST270973)Lex> | MGI:4258436
 
Name: SRC kinase signaling inhibitor 1; gene trap OST270973, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST317706)Lex> | MGI:4278158
 
Name: src family associated phosphoprotein 2; gene trap OST317706, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST317717)Lex> | MGI:4278164
 
Name: src family associated phosphoprotein 1; gene trap OST317717, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST319006)Lex> | MGI:4278826
 
Name: src family associated phosphoprotein 1; gene trap OST319006, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST326160)Lex> | MGI:4281328
 
Name: src family associated phosphoprotein 2; gene trap OST326160, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST357999)Lex> | MGI:4293134
 
Name: src family associated phosphoprotein 2; gene trap OST357999, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST358226)Lex> | MGI:4293197
 
Name: src family associated phosphoprotein 2; gene trap OST358226, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST379585)Lex> | MGI:4300392
 
Name: src family associated phosphoprotein 2; gene trap OST379585, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST380024)Lex> | MGI:4300541
 
Name: src family associated phosphoprotein 2; gene trap OST380024, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST413303)Lex> | MGI:4309246
 
Name: src family associated phosphoprotein 2; gene trap OST413303, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST422215)Lex> | MGI:4311927
 
Name: src family associated phosphoprotein 2; gene trap OST422215, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST443259)Lex> | MGI:4319223
 
Name: src family associated phosphoprotein 2; gene trap OST443259, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(OST455696)Lex> | MGI:4323587
 
Name: src family associated phosphoprotein 2; gene trap OST455696, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST465416)Lex> | MGI:4326457
 
Name: src family associated phosphoprotein 1; gene trap OST465416, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap1<Gt(OST473407)Lex> | MGI:4328864
 
Name: src family associated phosphoprotein 1; gene trap OST473407, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Skap2<Gt(VICTR20)21Lex> | MGI:4353991
Name: src family associated phosphoprotein 2; gene trap 21, Lexicon Genetics
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
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Allele
Srcin1<tm1(KOMP)Vlcg> | MGI:5293024
Name: SRC kinase signaling inhibitor 1; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Shf<tm1(KOMP)Vlcg> | MGI:5312363
Name: Src homology 2 domain containing F; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Lyn<M1Btlr> | MGI:5603319
Name: LYN proto-oncogene, Src family tyrosine kinase; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Hypomorph
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Allele
Srcin1<tm1.1(KOMP)Vlcg> | MGI:5603577
Name: SRC kinase signaling inhibitor 1; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Lyn<M2Btlr> | MGI:5613173
Name: LYN proto-oncogene, Src family tyrosine kinase; mutation 2, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Allele
Skap2<tm1Momo> | MGI:5645965
Name: src family associated phosphoprotein 2; targeted mutation 1, Takashi Momoi
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Lyn<M3Btlr> | MGI:5806331
Name: LYN proto-oncogene, Src family tyrosine kinase; mutation 3, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Allele
Lyn<m4Btlr> | MGI:6285919
Name: LYN proto-oncogene, Src family tyrosine kinase; mutation 4, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Allele
Srcin1<tm1.1Pdfi> | MGI:6423109
Name: SRC kinase signaling inhibitor 1; targeted mutation 1.1, Paola Defilippi
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Skap2<em1Cya> | MGI:7796147
Name: src family associated phosphoprotein 2; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Skap2<em2Cya> | MGI:7796148
Name: src family associated phosphoprotein 2; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Lyn/Lyn
Background: C57BL/6-Lyn
Zygosity: hm
Has Mutant Allele: true
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Publication
15284240 | -
First Author: Shapiro MJ
Year: 2004
Journal: J Biol Chem
Title: The ALX Src homology 2 domain is both necessary and sufficient to inhibit T cell receptor/CD28-mediated up-regulation of RE/AP.
Volume: 279
Issue: 39
Pages: 40647-52
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Publication
10517501 | J:59531
First Author: Maddalena AS
Year: 1999
Journal: Brain Pathol
Title: No complementation between TP53 or RB-1 and v-src in astrocytomas of GFAP-v-src transgenic mice.
Volume: 9
Issue: 4
Pages: 627-37
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Publication
21187437 | J:168915
First Author: Kamen LA
Year: 2011
Journal: J Immunol
Title: Pyk2 is required for neutrophil degranulation and host defense responses to bacterial infection.
Volume: 186
Issue: 3
Pages: 1656-65
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GO Term
GO:0034996 | RasGAP-Fyn-Lyn-Yes complex
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Publication
17086186 | J:116120
First Author: Mócsai A
Year: 2006
Journal: Nat Immunol
Title: Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs.
Volume: 7
Issue: 12
Pages: 1326-33
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Publication
10809671 | J:62182
First Author: Lai KM
Year: 2000
Journal: Genes Dev
Title: The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryo.
Volume: 14
Issue: 9
Pages: 1132-45
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Protein
P98083
Organism: Mus musculus/domesticus
Length: 579  
Fragment?: false
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Publication
11684687 | -
First Author: Pursglove SE
Year: 2002
Journal: J Biol Chem
Title: The solution structure and intramolecular associations of the Tec kinase SRC homology 3 domain.
Volume: 277
Issue: 1
Pages: 755-62
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Publication
17537434 | -
First Author: Rönty M
Year: 2007
Journal: Exp Cell Res
Title: Palladin interacts with SH3 domains of SPIN90 and Src and is required for Src-induced cytoskeletal remodeling.
Volume: 313
Issue: 12
Pages: 2575-85
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Publication
18432193 | -
First Author: Ziegenfuss JS
Year: 2008
Journal: Nature
Title: Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling.
Volume: 453
Issue: 7197
Pages: 935-9
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Publication
19362019 | J:147963
First Author: Charles N
Year: 2009
Journal: Immunity
Title: Lyn kinase controls basophil GATA-3 transcription factor expression and induction of Th2 cell differentiation.
Volume: 30
Issue: 4
Pages: 533-43
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Publication
26777396 | J:259937
First Author: Volmering S
Year: 2016
Journal: Immunity
Title: The Neutrophil Btk Signalosome Regulates Integrin Activation during Sterile Inflammation.
Volume: 44
Issue: 1
Pages: 73-87
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Publication
20624892 | J:163472
First Author: Scapini P
Year: 2010
Journal: J Exp Med
Title: Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.
Volume: 207
Issue: 8
Pages: 1757-73
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Publication
29077881 | J:295872
First Author: Costantino S
Year: 2019
Journal: Eur Heart J
Title: Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity.
Volume: 40
Issue: 4
Pages: 383-391
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Publication
9817027 | -
First Author: Sawyer TK
Year: 1998
Journal: Biopolymers
Title: Src homology-2 domains: structure, mechanisms, and drug discovery.
Volume: 47
Issue: 3
Pages: 243-61
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Publication
18194650 | -
First Author: Gavard J
Year: 2008
Journal: Dev Cell
Title: Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia.
Volume: 14
Issue: 1
Pages: 25-36
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Publication
9712716 | -
First Author: Miyatake S
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Src family tyrosine kinases associate with and phosphorylate CTLA-4 (CD152).
Volume: 249
Issue: 2
Pages: 444-8
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Protein Coding Gene
MGI:107357 | Inpp5d
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:893579 | Khdrbs1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1345171 | Sh2b2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
31278282 | J:297007
First Author: Singh BN
Year: 2019
Journal: Sci Rep
Title: Etv2 transcriptionally regulates Yes1 and promotes cell proliferation during embryogenesis.
Volume: 9
Issue: 1
Pages: 9736
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Publication
25075770 | J:278464
First Author: Shahzad K
Year: 2015
Journal: Kidney Int
Title: Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy.
Volume: 87
Issue: 1
Pages: 74-84
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Publication
19828641 | J:156802
First Author: Giles AJ
Year: 2009
Journal: J Immunol
Title: The adaptor protein Shc plays a key role during early B cell development.
Volume: 183
Issue: 9
Pages: 5468-76
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Publication
15064729 | J:89585
First Author: Weissenberger J
Year: 2004
Journal: Oncogene
Title: IL-6 is required for glioma development in a mouse model.
Volume: 23
Issue: 19
Pages: 3308-16
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Publication
17218386 | J:145325
First Author: Cain JA
Year: 2007
Journal: Blood
Title: Myeloproliferative disease induced by TEL-PDGFRB displays dynamic range sensitivity to Stat5 gene dosage.
Volume: 109
Issue: 9
Pages: 3906-14
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Publication
21860019 | J:178397
First Author: Shao B
Year: 2011
Journal: Blood
Title: Carcinoma mucins trigger reciprocal activation of platelets and neutrophils in a murine model of Trousseau syndrome.
Volume: 118
Issue: 15
Pages: 4015-23
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Publication
26124096 | J:223727
First Author: Shao B
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: O-glycans direct selectin ligands to lipid rafts on leukocytes.
Volume: 112
Issue: 28
Pages: 8661-6
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Publication
8206383 | J:18729
First Author: Hébert B
Year: 1994
Journal: Gene
Title: Protein tyrosine kinases transcribed in a murine thymic medullary epithelial cell line.
Volume: 143
Issue: 2
Pages: 257-60
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Publication
38261611 | J:360275
First Author: Yin M
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: Tracking the role of Aire in immune tolerance to the eye with a TCR transgenic mouse model.
Volume: 121
Issue: 5
Pages: e2311487121
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Publication
31386299 | J:293547
First Author: Abou Nader N
Year: 2019
Journal: Genesis
Title: Yes-associated protein expression in germ cells is dispensable for spermatogenesis in mice.
Volume: 57
Issue: 10
Pages: e23330
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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