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Details |
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Asayesh A |
| Year: |
2006 |
| Journal: |
Genes Dev |
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Spleen versus pancreas: strict control of organ interrelationship revealed by analyses of Bapx1-/- mice. |
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20 |
| Issue: |
16 |
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2208-13 |
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•
•
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| First Author: |
Nishiyama S |
| Year: |
2010 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Over-expression of Tfam improves the mitochondrial disease phenotypes in a mouse model system. |
| Volume: |
401 |
| Issue: |
1 |
| Pages: |
26-31 |
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•
•
•
•
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| First Author: |
Yu HM |
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2005 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Development of a unique system for spatiotemporal and lineage-specific gene expression in mice. |
| Volume: |
102 |
| Issue: |
24 |
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•
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Morita T |
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Proc Natl Acad Sci U S A |
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A mouse homolog of the Escherichia coli recA and Saccharomyces cerevisiae RAD51 genes. |
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| Issue: |
14 |
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•
•
•
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| First Author: |
Encinas JA |
| Year: |
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Proc Natl Acad Sci U S A |
| Title: |
Cloning, expression, and genetic mapping of Sema W, a member of the semaphorin family. |
| Volume: |
96 |
| Issue: |
5 |
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•
•
•
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| First Author: |
Nguyen NT |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism. |
| Volume: |
107 |
| Issue: |
46 |
| Pages: |
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•
•
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| First Author: |
Kavaliers M |
| Year: |
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| Journal: |
Proc Natl Acad Sci U S A |
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Inadvertent social information and the avoidance of parasitized male mice: a role for oxytocin. |
| Volume: |
103 |
| Issue: |
11 |
| Pages: |
4293-8 |
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•
•
•
•
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| First Author: |
Liu NA |
| Year: |
2011 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Targeting zebrafish and murine pituitary corticotroph tumors with a cyclin-dependent kinase (CDK) inhibitor. |
| Volume: |
108 |
| Issue: |
20 |
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8414-9 |
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•
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| First Author: |
Díaz-Amarilla P |
| Year: |
2011 |
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Proc Natl Acad Sci U S A |
| Title: |
Phenotypically aberrant astrocytes that promote motoneuron damage in a model of inherited amyotrophic lateral sclerosis. |
| Volume: |
108 |
| Issue: |
44 |
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| First Author: |
Zhang Y |
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2014 |
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Proc Natl Acad Sci U S A |
| Title: |
An amphioxus RAG1-like DNA fragment encodes a functional central domain of vertebrate core RAG1. |
| Volume: |
111 |
| Issue: |
1 |
| Pages: |
397-402 |
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| First Author: |
Sun EW |
| Year: |
2019 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Lipid transporter TMEM24/C2CD2L is a Ca2+-regulated component of ER-plasma membrane contacts in mammalian neurons. |
| Volume: |
116 |
| Issue: |
12 |
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| First Author: |
Kumra H |
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Proc Natl Acad Sci U S A |
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Fibulin-4 exerts a dual role in LTBP-4L-mediated matrix assembly and function. |
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Massart J |
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Altered miR-29 Expression in Type 2 Diabetes Influences Glucose and Lipid Metabolism in Skeletal Muscle. |
| Volume: |
66 |
| Issue: |
7 |
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Üner AG |
| Year: |
2019 |
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Sci Rep |
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Role of POMC and AgRP neuronal activities on glycaemia in mice. |
| Volume: |
9 |
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1 |
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•
•
•
•
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| First Author: |
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Proc Natl Acad Sci U S A |
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Cloning of a phospholipase A2-activating protein. |
| Volume: |
88 |
| Issue: |
12 |
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•
•
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| First Author: |
Lee HJ |
| Year: |
2009 |
| Journal: |
Dev Dyn |
| Title: |
Novel markers of early ovarian pre-granulosa cells are expressed in an Sry-like pattern. |
| Volume: |
238 |
| Issue: |
4 |
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Guo Y |
| Year: |
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iScience |
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Steroidogenic factor 1 protects mice from obesity-induced glucose intolerance via improving glucose-stimulated insulin secretion by beta cells. |
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26 |
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4 |
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Hoshino A |
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Int Immunol |
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STAT6-mediated signaling in Th2-dependent allergic asthma: critical role for the development of eosinophilia, airway hyper-responsiveness and mucus hypersecretion, distinct from its role in Th2 differentiation. |
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| First Author: |
Lyubimova A |
| Year: |
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J Clin Invest |
| Title: |
Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice. |
| Volume: |
120 |
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2 |
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•
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| First Author: |
Semont A |
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Oncogene |
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Involvement of p53 and Fas/CD95 in murine neural progenitor cell response to ionizing irradiation. |
| Volume: |
23 |
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52 |
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•
•
•
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Seneviratne A |
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2020 |
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Circ Res |
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Hematoma Resolution In Vivo Is Directed by Activating Transcription Factor 1. |
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7 |
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| First Author: |
Miranda A |
| Year: |
2011 |
| Journal: |
PLoS One |
| Title: |
Prion protein expression regulates embryonic stem cell pluripotency and differentiation. |
| Volume: |
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4 |
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e18422 |
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Matsuzawa A |
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Eur J Immunol |
| Title: |
Lymphadenopathy induced by the cooperation between lprcg and gld genes is of lpr but not of gld phenotype. |
| Volume: |
24 |
| Issue: |
7 |
| Pages: |
1714-6 |
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•
•
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Chea S |
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2016 |
| Journal: |
Sci Signal |
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Notch signaling in group 3 innate lymphoid cells modulates their plasticity. |
| Volume: |
9 |
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426 |
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•
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| First Author: |
Buch BT |
| Year: |
2020 |
| Journal: |
FASEB J |
| Title: |
Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner. |
| Volume: |
34 |
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6 |
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Chaudhuri A |
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Mol Biol Evol |
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Evolution of messenger RNA structure and regulation in the genus Mus: the androgen-inducible RP2 mRNAs. |
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Millanes-Romero A |
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Mol Cell |
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Regulation of heterochromatin transcription by Snail1/LOXL2 during epithelial-to-mesenchymal transition. |
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Elledge HM |
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Proc Natl Acad Sci U S A |
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Structure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily members. |
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Aryl hydrocarbon receptor activation in genital tubercle, palate, and other embryonic tissues in 2,3,7, 8-tetrachlorodibenzo-p-dioxin-responsive lacZ mice. |
| Volume: |
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Defining the Microglia Response during the Time Course of Chronic Neurodegeneration. |
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| Organism: |
Mus musculus/domesticus |
| Length: |
86
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| Fragment?: |
true |
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Hsu LC |
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2015 |
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Proc Natl Acad Sci U S A |
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Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis. |
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Proc Natl Acad Sci U S A |
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TWEAK and RIPK1 mediate a second wave of cell death during AKI. |
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115 |
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Bøggild A |
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The crystal structure of the intact E. coli RelBE toxin-antitoxin complex provides the structural basis for conditional cooperativity. |
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10 |
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Nat Cell Biol |
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The armadillo protein p0071 regulates Rho signalling during cytokinesis. |
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Vera A |
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Front Cell Neurosci |
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SCO-spondin from embryonic cerebrospinal fluid is required for neurogenesis during early brain development. |
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Röhl A |
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EMBO Rep |
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Hop/Sti1 phosphorylation inhibits its co-chaperone function. |
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Solymosi EA |
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Proc Natl Acad Sci U S A |
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Chloride transport-driven alveolar fluid secretion is a major contributor to cardiogenic lung edema. |
| Volume: |
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PKC eta directs induction of IRF-4 expression and Ig kappa gene rearrangement in pre-BCR signaling pathway. |
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Tissue Antigens |
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Investigation of killer cell immunoglobulin-like receptor (KIR) gene diversity: KIR2DL2, KIR2DL5 and KIR2DS5. |
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An essential quality control mechanism at the eukaryotic basal body prior to intraflagellar transport. |
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Purohit A |
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J Cell Biol |
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Direct interaction of pericentrin with cytoplasmic dynein light intermediate chain contributes to mitotic spindle organization. |
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Fischer A |
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J Plant Physiol |
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Chan JC |
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Proc Natl Acad Sci U S A |
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A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. |
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Hum Mol Genet |
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CX3CR1 reduces Ly6Chigh-monocyte motility within and release from the bone marrow after chemotherapy in mice. |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
740
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| Fragment?: |
false |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
101
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| Fragment?: |
true |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
192
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| Fragment?: |
false |
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| Protein Domain |
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Family |
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A large group of bacterial exotoxins are referred to as "A/B toxins", essentially because they are formed from two subunits []. The "A"subunitpossesses enzyme activity, and is transferred to the host cell following a conformational change in the membrane-bound transport "B"subunit [].Bordetella pertussis is the causative agent of whooping cough, and is a Gram-negative aerobic coccus. Its major virulence factor is the pertussis toxin, an A/B exotoxin that mediates both colonisation and toxaemic stagesof the the disease [, ]. Recombinant, inactive forms of the 5 subunits that make up the toxin have proven to be good vaccines.The S1 ("A") subunit of pertussis toxin causes the characteristic sound of the "whoop"in whooping cough. It achieves this through ADP-ribosylation of host Gi alpha-units, an adenylate cyclase inhibitor [, ]. Uninhibited, this enzyme produces elevated levels of cAMP, leading to increased cell exudate and inflammation in the lungs [].The crystal structure of pertussis toxin has been determined to 2.9A resolution []. The catalytic A-subunit (S1) shares structural similarity with other ADP-ribosylating bacterial toxins, although differences in the C-terminal portion explain its unique activation mechanism. Despite itsheterogeneous subunit composition, the structure of the cell-bindingB-oligomer (S2, S3, two copies of S4, and S5) resembles the symmetricalB-pentamers of the cholera and shiga toxin families, but it interactsdifferently with the A-subunit and there is virtually no sequence similarity between B-subunits of the different toxins. |
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