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Search results 20701 to 20800 out of 23840 for Sry

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Type Details Score
Publication
18624832 | J:140421
First Author: Shibata S
Year: 2008
Journal: J Anat
Title: An in situ hybridization study of Runx2, Osterix, and Sox9 in the anlagen of mouse mandibular condylar cartilage in the early stages of embryogenesis.
Volume: 213
Issue: 3
Pages: 274-83
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Publication
19022741 | J:138685
 
First Author: de Vries WN
Year: 2008
Journal: Cold Spring Harb Symp Quant Biol
Title: Reprogramming and differentiation in mammals: motifs and mechanisms.
Volume: 73
Pages: 33-8
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Publication
19161225 | J:144181
First Author: Meng H
Year: 2009
Journal: Dev Dyn
Title: Differential expression of sphingosine-1-phosphate receptors 1-5 in the developing nervous system.
Volume: 238
Issue: 2
Pages: 487-500
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Publication
19287386 | J:150525
First Author: Cheng LC
Year: 2009
Journal: Nat Neurosci
Title: miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche.
Volume: 12
Issue: 4
Pages: 399-408
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Publication
19712269 | J:153077
First Author: Satake H
Year: 2009
Journal: Dev Growth Differ
Title: Spatio-temporal expression of activating transcription factor 5 in the skeletal development of mouse limb.
Volume: 51
Issue: 7
Pages: 669-76
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Publication
19952280 | J:158460
First Author: Vrljicak P
Year: 2010
Journal: Physiol Genomics
Title: Genomic analysis distinguishes phases of early development of the mouse atrio-ventricular canal.
Volume: 40
Issue: 3
Pages: 150-7
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Publication
20235171 | J:162681
First Author: Herde MK
Year: 2010
Journal: J Comp Neurol
Title: Developmental expression of the actin depolymerizing factor ADF in the mouse inner ear and spiral ganglia.
Volume: 518
Issue: 10
Pages: 1724-41
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Publication
19759178 | J:164476
First Author: Amano K
Year: 2009
Journal: Mol Biol Cell
Title: Sox9 family members negatively regulate maturation and calcification of chondrocytes through up-regulation of parathyroid hormone-related protein.
Volume: 20
Issue: 21
Pages: 4541-51
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Publication
21038449 | J:165546
First Author: García-Andrés C
Year: 2010
Journal: Dev Dyn
Title: Comparative expression pattern analysis of the highly conserved chemokines SDF1 and CXCL14 during amniote embryonic development.
Volume: 239
Issue: 10
Pages: 2769-77
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Publication
21472480 | J:173578
First Author: Parker MA
Year: 2011
Journal: J Assoc Res Otolaryngol
Title: TAK1 expression in the cochlea: a specific marker for adult supporting cells.
Volume: 12
Issue: 4
Pages: 471-83
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Publication
20646110 | J:175097
First Author: Lee SH
Year: 2010
Journal: J Anat
Title: Dynamic methylation and expression of Oct4 in early neural stem cells.
Volume: 217
Issue: 3
Pages: 203-13
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Publication
21699792 | J:175558
First Author: Wang X
Year: 2011
Journal: Gastroenterology
Title: Analysis of the sacral neural crest cell contribution to the hindgut enteric nervous system in the mouse embryo.
Volume: 141
Issue: 3
Pages: 992-1002.e1-6
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Publication
21872590 | J:176426
First Author: Yang J
Year: 2011
Journal: FEBS Lett
Title: MiR-140 is co-expressed with Wwp2-C transcript and activated by Sox9 to target Sp1 in maintaining the chondrocyte proliferation.
Volume: 585
Issue: 19
Pages: 2992-7
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Publication
21703370 | J:176483
First Author: Holmes G
Year: 2011
Journal: Bone
Title: The Sox2 high mobility group transcription factor inhibits mature osteoblast function in transgenic mice.
Volume: 49
Issue: 4
Pages: 653-61
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Publication
22072985 | J:177991
First Author: Leung VY
Year: 2011
Journal: PLoS Genet
Title: SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression.
Volume: 7
Issue: 11
Pages: e1002356
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Publication
22085726 | J:178822
First Author: Bergsland M
Year: 2011
Journal: Genes Dev
Title: Sequentially acting Sox transcription factors in neural lineage development.
Volume: 25
Issue: 23
Pages: 2453-64
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Publication
22546692 | J:185807
First Author: Nowotschin S
Year: 2012
Journal: Dev Biol
Title: Interaction of Wnt3a, Msgn1 and Tbx6 in neural versus paraxial mesoderm lineage commitment and paraxial mesoderm differentiation in the mouse embryo.
Volume: 367
Issue: 1
Pages: 1-14
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Publication
22223437 | J:186281
First Author: Ding M
Year: 2012
Journal: J Cell Physiol
Title: Targeting Runx2 expression in hypertrophic chondrocytes impairs endochondral ossification during early skeletal development.
Volume: 227
Issue: 10
Pages: 3446-56
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Publication
22973011 | J:188114
First Author: Munnamalai V
Year: 2012
Journal: J Neurosci
Title: Notch prosensory effects in the Mammalian cochlea are partially mediated by Fgf20.
Volume: 32
Issue: 37
Pages: 12876-84
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Publication
23277114 | J:194992
First Author: Zhu MY
Year: 2013
Journal: Gene Expr Patterns
Title: The expression of NOTCH2, HES1 and SOX9 during mouse retinal development.
Volume: 13
Issue: 3-4
Pages: 78-83
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Publication
23474895 | J:195303
First Author: Aksoy I
Year: 2013
Journal: EMBO J
Title: Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm.
Volume: 32
Issue: 7
Pages: 938-53
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Publication
23449223 | J:200656
First Author: Mead TJ
Year: 2013
Journal: Nucleic Acids Res
Title: A far-upstream (-70 kb) enhancer mediates Sox9 auto-regulation in somatic tissues during development and adult regeneration.
Volume: 41
Issue: 8
Pages: 4459-69
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Publication
23644063 | J:202185
First Author: Bondurand N
Year: 2013
Journal: Dev Biol
Title: The role of SOX10 during enteric nervous system development.
Volume: 382
Issue: 1
Pages: 330-43
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Publication
24038449 | J:203065
First Author: Sugiyama T
Year: 2013
Journal: Dev Dyn
Title: The germinal matrices in the developing dentate gyrus are composed of neuronal progenitors at distinct differentiation stages.
Volume: 242
Issue: 12
Pages: 1442-53
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Publication
24990742 | J:213642
First Author: Cooper KL
Year: 2014
Journal: Nature
Title: Patterning and post-patterning modes of evolutionary digit loss in mammals.
Volume: 511
Issue: 7507
Pages: 41-5
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Publication
23720416 | J:226380
First Author: Bery A
Year: 2014
Journal: Cereb Cortex
Title: Characterization of enhancers active in the mouse embryonic cerebral cortex suggests Sox/Pou cis-regulatory logics and heterogeneity of cortical progenitors.
Volume: 24
Issue: 11
Pages: 2822-34
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Publication
26494792 | J:226612
First Author: Bankaitis ED
Year: 2015
Journal: Genes Dev
Title: Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche.
Volume: 29
Issue: 20
Pages: 2203-16
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Publication
26538639 | J:227121
First Author: Gaete M
Year: 2015
Journal: Biol Open
Title: Epithelial topography for repetitive tooth formation.
Volume: 4
Issue: 12
Pages: 1625-34
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Publication
26453549 | J:227640
 
First Author: Economou C
Year: 2015
Journal: BMC Dev Biol
Title: Intrinsic factors and the embryonic environment influence the formation of extragonadal teratomas during gestation.
Volume: 15
Pages: 35
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Publication
27585883 | J:236786
First Author: Bergeron KF
Year: 2016
Journal: Dis Model Mech
Title: Upregulation of the Nr2f1-A830082K12Rik gene pair in murine neural crest cells results in a complex phenotype reminiscent of Waardenburg syndrome type 4.
Volume: 9
Issue: 11
Pages: 1283-1293
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Publication
27250101 | J:238162
First Author: Muinos-López E
Year: 2016
Journal: Stem Cells
Title: Hypoxia and Reactive Oxygen Species Homeostasis in Mesenchymal Progenitor Cells Define a Molecular Mechanism for Fracture Nonunion.
Volume: 34
Issue: 9
Pages: 2342-53
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Publication
27369076 | J:238590
First Author: Hayashi K
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Involvement of the T-box transcription factor Brachyury in early-stage embryonic mouse salivary gland.
Volume: 477
Issue: 4
Pages: 814-819
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Publication
28013293 | J:241435
First Author: Jin F
Year: 2017
Journal: Hum Mol Genet
Title: Deficient TSC1/TSC2-complex suppression of SOX9-osteopontin-AKT signalling cascade constrains tumour growth in tuberous sclerosis complex.
Volume: 26
Issue: 2
Pages: 407-419
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Publication
39629665 | J:359861
 
First Author: Kay RGG
Year: 2024
Journal: Development
Title: Gonadal sex reversal at single-cell resolution in Znrf3-deficient mice.
Volume: 151
Issue: 23
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Publication
28733161 | J:249803
First Author: Guerrero-Flores G
Year: 2017
Journal: Dev Biol
Title: Functional determination of the differentiation potential of ventral mesencephalic neural precursor cells during dopaminergic neurogenesis.
Volume: 429
Issue: 1
Pages: 56-70
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Publication
29023691 | J:257638
First Author: Higashiyama H
Year: 2018
Journal: J Anat
Title: Anatomy and development of the extrahepatic biliary system in mouse and rat: a perspective on the evolutionary loss of the gallbladder.
Volume: 232
Issue: 1
Pages: 134-145
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Publication
29383478 | J:261596
First Author: Schilders K
Year: 2018
Journal: Transgenic Res
Title: Generation of a biotinylatable Sox2 mouse model to identify Sox2 complexes in vivo.
Volume: 27
Issue: 1
Pages: 75-85
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Publication
29929043 | J:265842
 
First Author: Palagano E
Year: 2018
Journal: Bone
Title: Mutations in the Neuroblastoma Amplified Sequence gene in a family affected by Acrofrontofacionasal Dysostosis type 1.
Volume: 114
Pages: 125-136
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Publication
30737693 | J:274906
 
First Author: McGlinn E
Year: 2019
Journal: Methods Mol Biol
Title: Detection of Gene and Protein Expression in Mouse Embryos and Tissue Sections.
Volume: 1920
Pages: 183-218
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Publication
31160421 | J:278226
 
First Author: Bastidas-Ponce A
Year: 2019
Journal: Development
Title: Comprehensive single cell mRNA profiling reveals a detailed roadmap for pancreatic endocrinogenesis.
Volume: 146
Issue: 12
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Publication
32020708 | J:289913
First Author: Omotehara T
Year: 2020
Journal: Dev Dyn
Title: Connection between seminiferous tubules and epididymal duct is originally induced before sex differentiation in a sex-independent manner.
Volume: 249
Issue: 6
Pages: 754-764
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Publication
32852840 | J:297658
     
First Author: Kulibin AY
Year: 2020
Journal: Dev Dyn
Title: Formation of the rete testis during mouse embryonic development.
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Publication
27100146 | J:302850
First Author: Liu M
Year: 2016
Journal: Hepatology
Title: CHD1L promotes lineage reversion of hepatocellular carcinoma through opening chromatin for key developmental transcription factors.
Volume: 63
Issue: 5
Pages: 1544-59
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Publication
26806292 | J:317374
 
First Author: Zhang M
Year: 2016
Journal: Int J Biochem Cell Biol
Title: Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage.
Volume: 72
Pages: 125-134
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Publication
34276786 | J:308611
 
First Author: Bian H
Year: 2021
Journal: Front Genet
Title: Expression Profiling and Functional Analysis of Candidate Col10a1 Regulators Identified by the TRAP Program.
Volume: 12
Pages: 683939
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Publication
34266958 | J:308134
 
First Author: Yu HV
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: POU4F3 pioneer activity enables ATOH1 to drive diverse mechanoreceptor differentiation through a feed-forward epigenetic mechanism.
Volume: 118
Issue: 29
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Publication
25380565 | J:309374
First Author: Haraguchi R
Year: 2015
Journal: Cell Tissue Res
Title: Epigenetic regulation of Tbx18 gene expression during endochondral bone formation.
Volume: 359
Issue: 2
Pages: 503-512
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Publication
34184730 | J:308524
 
First Author: Morgani SM
Year: 2021
Journal: Biol Open
Title: Quantitative analysis of signaling responses during mouse primordial germ cell specification.
Volume: 10
Issue: 5
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Publication
33810480 | J:307544
 
First Author: Burtscher I
Year: 2021
Journal: Int J Mol Sci
Title: Generation of a Novel Nkx6-1 Venus Fusion Reporter Mouse Line.
Volume: 22
Issue: 7
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Publication
29969095 | J:310384
   
First Author: Bonnet F
Year: 2018
Journal: Elife
Title: Neurogenic decisions require a cell cycle independent function of the CDC25B phosphatase.
Volume: 7
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Publication
27523618 | J:310876
First Author: Jiang H
Year: 2016
Journal: Stem Cell Reports
Title: Immune Regulator MCPIP1 Modulates TET Expression during Early Neocortical Development.
Volume: 7
Issue: 3
Pages: 439-453
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Publication
34557485 | J:311153
 
First Author: Gahankari A
Year: 2021
Journal: Front Cell Dev Biol
Title: Deregulated Rac1 Activity in Neural Crest Controls Cell Proliferation, Migration and Differentiation During Midbrain Development.
Volume: 9
Pages: 704769
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Publication
24917674 | J:314657
First Author: Lin S
Year: 2014
Journal: J Biol Chem
Title: Constitutive nuclear expression of dentin matrix protein 1 fails to rescue the Dmp1-null phenotype.
Volume: 289
Issue: 31
Pages: 21533-43
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Publication
33754063 | J:308974
First Author: Guo S
Year: 2021
Journal: Theranostics
Title: Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development.
Volume: 11
Issue: 9
Pages: 4316-4334
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Publication
25754147 | J:316722
First Author: Sun S
Year: 2015
Journal: Neurosci Bull
Title: Dose-dependent regulation of oligodendrocyte specification by β-catenin signaling.
Volume: 31
Issue: 2
Pages: 271-3
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Publication
29141232 | J:313372
First Author: Braccioli L
Year: 2017
Journal: Stem Cell Reports
Title: FOXP1 Promotes Embryonic Neural Stem Cell Differentiation by Repressing Jagged1 Expression.
Volume: 9
Issue: 5
Pages: 1530-1545
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Publication
24120664 | J:310134
First Author: Adachi K
Year: 2013
Journal: Mol Cell
Title: Context-dependent wiring of Sox2 regulatory networks for self-renewal of embryonic and trophoblast stem cells.
Volume: 52
Issue: 3
Pages: 380-92
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Publication
24647733 | J:310447
First Author: Zhang P
Year: 2014
Journal: J Mol Neurosci
Title: Protocadherin 11 x regulates differentiation and proliferation of neural stem cell in vitro and in vivo.
Volume: 54
Issue: 2
Pages: 199-210
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Publication
34880251 | J:317045
First Author: Cheng W
Year: 2021
Journal: Nat Commun
Title: Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma.
Volume: 12
Issue: 1
Pages: 7142
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Publication
25708924 | J:320309
First Author: Rezza A
Year: 2015
Journal: Exp Dermatol
Title: PDGF signalling in the dermis and in dermal condensates is dispensable for hair follicle induction and formation.
Volume: 24
Issue: 6
Pages: 468-70
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Publication
32450490 | J:320539
 
First Author: Manning J
Year: 2020
Journal: J Proteomics
Title: Identification of novel interacting partners of the NEDD4 ubiquitin ligase in mouse testis.
Volume: 223
Pages: 103830
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Publication
23243273 | J:320762
First Author: Kingsley PD
Year: 2013
Journal: Blood
Title: Ontogeny of erythroid gene expression.
Volume: 121
Issue: 6
Pages: e5-e13
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Publication
36124393 | J:332292
First Author: Zhang Y
Year: 2022
Journal: Hum Mutat
Title: Mutations in the TBX15-ADAMTS2 pathway associate with a novel soft palate dysplasia.
Volume: 43
Issue: 12
Pages: 2102-2115
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Publication
35878429 | J:327294
 
First Author: Yang H
Year: 2022
Journal: Biochem Biophys Res Commun
Title: SOXE group transcription factors regulates the expression of FoxG1 during inner ear development.
Volume: 623
Pages: 96-103
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Publication
36602864 | J:333395
 
First Author: Gunawardhana KL
Year: 2023
Journal: J Clin Invest
Title: A systems biology approach identifies the role of dysregulated PRDM6 in the development of hypertension.
Volume: 133
Issue: 4
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Publication
37419903 | J:337971
First Author: Kohler TN
Year: 2023
Journal: Nat Commun
Title: Plakoglobin is a mechanoresponsive regulator of naive pluripotency.
Volume: 14
Issue: 1
Pages: 4022
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Publication
37519269 | J:340721
 
First Author: Schindler M
Year: 2023
Journal: Development
Title: Induction of kidney-related gene programs through co-option of SALL1 in mole ovotestes.
Volume: 150
Issue: 17
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Publication
36517595 | J:340447
First Author: Zhai J
Year: 2022
Journal: Nature
Title: Primate gastrulation and early organogenesis at single-cell resolution.
Volume: 612
Issue: 7941
Pages: 732-738
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Publication
37681879 | J:340444
 
First Author: Veithen M
Year: 2023
Journal: Cells
Title: Sox9 Inhibits Cochlear Hair Cell Fate by Upregulating Hey1 and HeyL Antagonists of Atoh1.
Volume: 12
Issue: 17
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Publication
37806494 | J:342842
First Author: Su D
Year: 2023
Journal: J Biol Chem
Title: Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development.
Volume: 299
Issue: 11
Pages: 105324
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Publication
33135541 | J:346179
First Author: Abe S
Year: 2021
Journal: Epigenetics
Title: A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation.
Volume: 16
Issue: 10
Pages: 1123-1134
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Publication
38791273 | J:348861
 
First Author: Aberle T
Year: 2024
Journal: Int J Mol Sci
Title: Sox10 Activity and the Timing of Schwann Cell Differentiation Are Controlled by a Tle4-Dependent Negative Feedback Loop.
Volume: 25
Issue: 10
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Publication
39168984 | J:353382
First Author: Strasser AS
Year: 2024
Journal: Nat Commun
Title: Limb reduction in an Esco2 cohesinopathy mouse model is mediated by p53-dependent apoptosis and vascular disruption.
Volume: 15
Issue: 1
Pages: 7154
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Publication
38408234 | J:353363
First Author: Gao J
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: CHD7 and SOX2 act in a common gene regulatory network during mammalian semicircular canal and cochlear development.
Volume: 121
Issue: 10
Pages: e2311720121
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Publication
38899779 | J:353660
First Author: Saeki N
Year: 2024
Journal: Hum Mol Genet
Title: Deletion of Trps1 regulatory elements recapitulates postnatal hip joint abnormalities and growth retardation of Trichorhinophalangeal syndrome in mice.
Volume: 33
Issue: 18
Pages: 1618-1629
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Publication
39684410 | J:359855
 
First Author: Gil Y
Year: 2024
Journal: Int J Mol Sci
Title: Molecular Characterization of Subdomain Specification of Cochlear Duct Based on Foxg1 and Gata3.
Volume: 25
Issue: 23
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Publication
23060611 | J:356402
First Author: Nusinow DP
Year: 2012
Journal: Bioinformatics
Title: Network-based inference from complex proteomic mixtures using SNIPE.
Volume: 28
Issue: 23
Pages: 3115-22
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Publication
26234751 | J:223062
First Author: Palmer K
Year: 2016
Journal: Dev Biol
Title: Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology.
Volume: 415
Issue: 2
Pages: 216-227
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Itgb1/Itgb1 Sox10/Sox10<+> Tg(PLAT-cre)116Sdu/?
Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Publication
- | J:159099
     
First Author: McMahon A
Year: 2010
Journal: Unpublished
Title: Summary of mouse strains characterized by GUDMAP consortium.
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Publication
23918385 | J:200671
First Author: Economides AN
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Conditionals by inversion provide a universal method for the generation of conditional alleles.
Volume: 110
Issue: 34
Pages: E3179-88
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Protein
P53784
Organism: Mus musculus/domesticus
Length: 375  
Fragment?: false
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Protein
A2AM37
Organism: Mus musculus/domesticus
Length: 450  
Fragment?: false
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Protein
Q6P564
Organism: Mus musculus/domesticus
Length: 448  
Fragment?: true
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Protein
Q4VBD8
Organism: Mus musculus/domesticus
Length: 436  
Fragment?: true
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Protein
Q5RKW0
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: true
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Publication
29393534 | J:275185
First Author: Nagasawa K
Year: 2018
Journal: Mol Reprod Dev
Title: Regionally distinct patterns of STAT3 phosphorylation in the seminiferous epithelia of mouse testes.
Volume: 85
Issue: 3
Pages: 262-270
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Publication
27742779 | J:239332
First Author: Vernet N
Year: 2016
Journal: Hum Mol Genet
Title: Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes.
Volume: 25
Issue: 24
Pages: 5300-5310
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Publication
10601091 | J:59032
First Author: Vogel T
Year: 1999
Journal: Hum Reprod
Title: Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.
Volume: 14
Issue: 12
Pages: 3023-9
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Publication
17952068 | J:128462
First Author: Quinn JJ
Year: 2007
Journal: Nat Neurosci
Title: Sex chromosome complement regulates habit formation.
Volume: 10
Issue: 11
Pages: 1398-400
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Publication
18443225 | J:136240
First Author: Smith-Bouvier DL
Year: 2008
Journal: J Exp Med
Title: A role for sex chromosome complement in the female bias in autoimmune disease.
Volume: 205
Issue: 5
Pages: 1099-108
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Genotype
Genotype
Symbol: Del(Y)1H/? Tg(Sry)2Ei/?
Background: involves: C57BL/6Ei * MF1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(Y)1H/? Tg(Sry)2Ei/?
Background: involves: MF1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(Y)2H/?
Background: mixed
Zygosity: ot
Has Mutant Allele: true
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Publication
- | J:30359
       
First Author: Sundberg JP (ed.)
Year: 1994
Title: Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools
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Protein Domain
IPR009071 | HMG_box_dom
Type: Domain
Description: High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs.HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors []; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation []; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor []; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi []; and the YABBY plant-specific transcription factors.
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Protein Domain
IPR036910 | HMG_box_dom_sf
Type: Homologous_superfamily
Description: High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs.HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors []; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation []; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor []; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi []; and the YABBY plant-specific transcription factors. Structurally, the HMG box domain is composed of three helices.
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Publication
10655590 | J:60190
First Author: Golding JP
Year: 2000
Journal: Nat Cell Biol
Title: Defects in pathfinding by cranial neural crest cells in mice lacking the neuregulin receptor ErbB4.
Volume: 2
Issue: 2
Pages: 103-9
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Publication
33854232 | J:305884
First Author: Maiani E
Year: 2021
Journal: Nature
Title: AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.
Volume: 592
Issue: 7856
Pages: 799-803
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Publication
21613327 | J:173574
First Author: Monk KR
Year: 2011
Journal: Development
Title: Gpr126 is essential for peripheral nerve development and myelination in mammals.
Volume: 138
Issue: 13
Pages: 2673-80
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